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Effects of Behavioral Contingencies on Effects of Nitrous Oxide - 12

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00000260
First Posted: September 21, 1999
Last Update Posted: May 27, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
National Institute on Drug Abuse (NIDA)
Information provided by (Responsible Party):
University of Chicago
  Purpose
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used to assess reinforcing effects. Comparisons between nitrous oxide, opiates, and benzodiazepine antagonists will be made. To examine the effects of different behavioral contingencies in modulating the reinforcing effects of nitrous oxide in healthy volunteers.

Condition Intervention
Opioid-Related Disorders Substance-Related Disorders Drug: Nitrous oxide

Study Type: Interventional
Official Title: Effects of Behavioral Contingencies on Effects of Nitrous Oxide

Resource links provided by NLM:


Further study details as provided by University of Chicago:

Primary Outcome Measures:
  • Mood
  • Choice of nitrous oxide vs placebo

Enrollment: 18
Study Start Date: June 1997
Study Completion Date: January 1998
Primary Completion Date: January 1998 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   21 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria
Please contact site for information.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000260


Locations
United States, Illinois
University of Chicago, Anesthesia & Critical Care
Chicago, Illinois, United States, 60637
Sponsors and Collaborators
University of Chicago
National Institute on Drug Abuse (NIDA)
Investigators
Principal Investigator: James Zacny, Ph.D. University of Chicago
  More Information

Responsible Party: University of Chicago
ClinicalTrials.gov Identifier: NCT00000260     History of Changes
Other Study ID Numbers: NIDA-08391-12
R01DA008391 ( U.S. NIH Grant/Contract )
R01-08391-12
First Submitted: September 20, 1999
First Posted: September 21, 1999
Last Update Posted: May 27, 2015
Last Verified: May 2015

Keywords provided by University of Chicago:
nitrous oxide
subjective effects
reinforcer
inhalant
healthy volunteer

Additional relevant MeSH terms:
Disease
Substance-Related Disorders
Opioid-Related Disorders
Pathologic Processes
Chemically-Induced Disorders
Mental Disorders
Nitrous Oxide
Anesthetics, Inhalation
Anesthetics, General
Anesthetics
Central Nervous System Depressants
Physiological Effects of Drugs
Analgesics, Non-Narcotic
Analgesics
Sensory System Agents
Peripheral Nervous System Agents