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IV Cocaine Abuse: A Laboratory Model - 4

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00000215
First Posted: September 21, 1999
Last Update Posted: January 12, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
Columbia University
Information provided by:
National Institute on Drug Abuse (NIDA)
  Purpose
The purpose of this study is to evaluate the effects of pergolide on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving in non-opiate dependent cocaine users.

Condition Intervention Phase
Cocaine-Related Disorders Drug: Pergolide Phase 2

Study Type: Interventional
Study Design: Primary Purpose: Treatment
Official Title: IV Cocaine Abuse: A Laboratory Model

Resource links provided by NLM:


Further study details as provided by National Institute on Drug Abuse (NIDA):

Primary Outcome Measures:
  • Direct cocaine effects (cardio, subjective)
  • Interaction of cocaine/pergolide on cardio
  • Interaction of coc/pergolide on coc's subjective
  • Effects of pergolide on cocaine craving

Estimated Enrollment: 0
Estimated Study Completion Date: December 2001
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 45 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria
Please contact site for information.
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000215


Locations
United States, New York
Columbia University
New York, New York, United States, 10023
Sponsors and Collaborators
National Institute on Drug Abuse (NIDA)
Columbia University
Investigators
Principal Investigator: Richard Foltin, Ph.D. Columbia University
  More Information

ClinicalTrials.gov Identifier: NCT00000215     History of Changes
Other Study ID Numbers: NIDA-06234-4
R01-06234-4
First Submitted: September 20, 1999
First Posted: September 21, 1999
Last Update Posted: January 12, 2017
Last Verified: October 2016

Keywords provided by National Institute on Drug Abuse (NIDA):
cocaine dependence

Additional relevant MeSH terms:
Cocaine-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Cocaine
Pergolide
Anesthetics, Local
Anesthetics
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Vasoconstrictor Agents
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Dopamine Agents
Neurotransmitter Agents
Dopamine Agonists