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IV Cocaine Abuse: A Laboratory Model - 2

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ClinicalTrials.gov Identifier: NCT00000213
Recruitment Status : Completed
First Posted : September 21, 1999
Last Update Posted : August 28, 2015
Sponsor:
Collaborators:
National Institute on Drug Abuse (NIDA)
Columbia University
Information provided by (Responsible Party):
New York State Psychiatric Institute

Brief Summary:
The purpose of this study is to evaluate the effects of fluoxetine maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving.

Condition or disease Intervention/treatment Phase
Cocaine-Related Disorders Drug: Fluoxetine Phase 2

Study Type : Interventional  (Clinical Trial)
Enrollment : 0 participants
Primary Purpose: Treatment
Official Title: IV Cocaine Abuse: A Laboratory Model
Study Start Date : April 1990
Actual Primary Completion Date : April 1991
Actual Study Completion Date : April 1991

Resource links provided by the National Library of Medicine





Primary Outcome Measures :
  1. Direct cocaine effects
  2. Interaction of cocaine/fluox. on cardio measures
  3. Interaction of cocaine/fluox. on coc's subjective
  4. Effects of fluoxetine on cocaine craving
  5. Drug use during outpatient fluoxetine maintenance


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Ages Eligible for Study:   18 Years to 45 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria
Please contact site for information.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000213


Locations
United States, New York
Columbia University
New York, New York, United States, 10023
Sponsors and Collaborators
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)
Columbia University
Investigators
Principal Investigator: Richard Foltin, Ph.D. Columbia University

Responsible Party: New York State Psychiatric Institute
ClinicalTrials.gov Identifier: NCT00000213     History of Changes
Other Study ID Numbers: NIDA-06234-2
R01DA006234 ( U.S. NIH Grant/Contract )
R01-06234-2
First Posted: September 21, 1999    Key Record Dates
Last Update Posted: August 28, 2015
Last Verified: December 2012

Keywords provided by New York State Psychiatric Institute:
intravenous abuse

Additional relevant MeSH terms:
Cocaine-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Cocaine
Fluoxetine
Anesthetics, Local
Anesthetics
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Vasoconstrictor Agents
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Dopamine Agents
Neurotransmitter Agents
Serotonin Uptake Inhibitors
Serotonin Agents
Antidepressive Agents, Second-Generation
Antidepressive Agents
Psychotropic Drugs
Cytochrome P-450 CYP2D6 Inhibitors
Cytochrome P-450 Enzyme Inhibitors
Enzyme Inhibitors