We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Does Lead Burden Alter Neuropsychological Development?

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00000104
First Posted: November 4, 1999
Last Update Posted: December 9, 2005
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
HRSA/Maternal and Child Health Bureau
Information provided by:
National Center for Research Resources (NCRR)
  Purpose
Inner city children are at an increased risk for lead overburden. This in turn affects cognitive functioning. However, the underlying neuropsychological effects of lead overburden and its age-specific effects have not been well delineated. This study is part of a larger study on the effects of lead overburden on the development of attention and memory. The larger study is using a multi-model approach to study the effects of lead overburden on these effects including the event-related potential (ERP), electrophysiologic measures of attention and memory are studied. Every eight months, for a total of three sessions the subjects will complete ERP measures of attention and memory which require them to watch various computer images while wearing scalp electrodes recording from 11 sites. It is this test that we are going to be doing on CRC. There will be 30 lead overburdened children recruited from the larger study for participation in the ERP studies on CRC. These 30 children will be matched with 30 children without lead overburden. This portion of the study is important in providing an index of physiological functioning to be used along with behaviorally based measures of attention and memory, and for providing information about the different measures.

Condition Intervention
Lead Poisoning Procedure: ERP measures of attention and memory

Study Type: Observational
Study Design: Observational Model: Defined Population
Time Perspective: Longitudinal

Resource links provided by NLM:


Further study details as provided by National Center for Research Resources (NCRR):

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Pregnant mothers of the Phillips neighborhood in Minneapolis, Minnesota. Subject recruitment will take place in local clinics which serve pregnant women and offspring
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00000104


Locations
United States, Minnesota
Department of Neurology 420 Delaware St. SE, Box 486 Mayo
Minneapolis, Minnesota, United States, 55455
Sponsors and Collaborators
National Center for Research Resources (NCRR)
HRSA/Maternal and Child Health Bureau
  More Information

ClinicalTrials.gov Identifier: NCT00000104     History of Changes
Other Study ID Numbers: NCRR-M01RR00400-0587
M01RR000400 ( U.S. NIH Grant/Contract )
First Submitted: November 3, 1999
First Posted: November 4, 1999
Last Update Posted: December 9, 2005
Last Verified: December 2003

Keywords provided by National Center for Research Resources (NCRR):
lead overburden

Additional relevant MeSH terms:
Poisoning
Lead Poisoning
Chemically-Induced Disorders