| 1 |
NCT02257437 |
Completed |
Acceptability of a Multiple Micronutrient-Fortified Lipid-Based Nutrient Supplement for Children Under Two in Cambodia |
|
- Dietary Supplement: LNS snack
- Dietary Supplement: Corn-soy blend ++ (CSB++)
- Dietary Supplement: Sprinkles
- Dietary Supplement: LNS + borbor
|
Interventional
|
Not Applicable |
- Institut de Recherche pour le Developpement, Cambodia
- UNICEF
- Department of Fisheries Post-harvest Technologies and Quality Control
- Institut de Recherche pour le Developpement, Cambodia
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Child's consumption
- Child's preference
- Mother's ranking
|
92 |
All |
9 Months to 23 Months (Child) |
NCT02257437 |
LNS-CAMB-INFANTS |
|
June 2015 |
July 2015 |
July 2015 |
October 6, 2014 |
September 15, 2016 |
|
- IRD Cambodia
Phnom Penh, Cambodia
|
|
| 2 |
NCT02361541 |
Completed |
Determination of HCV Prevalence in a HIV Patient Cohort in Phnom Penh, Cambodia |
|
|
Observational
|
|
- Institute of Tropical Medicine, Belgium
- Sihanouk Hospital Center of HOPE (SHCH), Phnom Penh, Cambodia
- Universiteit Antwerpen
|
Other |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
- Seroprevalence of HCV infection
- Proportion of current HCV infection
- Proportion of HCV false-positives
- (and 3 more...)
|
3045 |
All |
18 Years and older (Adult, Older Adult) |
NCT02361541 |
HCV-Epi |
HCV-Epi |
November 2014 |
April 2016 |
April 2016 |
February 11, 2015 |
May 16, 2016 |
|
- Sihanouk Hospital Center of HOPE (SHCH), Cambodia
Phnom Penh, Cambodia
|
|
| 3 |
NCT03117842 |
Recruiting |
Using a Theory-based SMS/VM Intervention to Improve Sexual and Reproductive Health of Female Entertainment Workers in Cambodia |
- Reproductive Health
- Sexual Health
|
- Other: Automated text and voice messages
|
Interventional
|
Not Applicable |
- Touro University, California
- KHANA Center for Population Health Research, Cambodia
|
Other |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Health Services Research
|
- Recent HIV Testing
- Condom Use with Clients
- Condom Use with boyfriend/husband/romantic partner
- (and 6 more...)
|
600 |
Female |
Child, Adult, Older Adult |
NCT03117842 |
mobilelinkcambodia |
|
April 1, 2018 |
September 1, 2018 |
April 1, 2019 |
April 18, 2017 |
April 20, 2018 |
|
- KHANA
Phnom Penh, Cambodia
|
|
| 4 |
NCT02628691 |
Terminated |
Monitoring Liver Disease Progression in Hepatitis C/HIV Co-infected Patients With No-to-moderate Fibrosis, in Phnom Penh, Cambodia |
|
- Other: Liver fibrosis progression
|
Observational
|
|
- Institute of Tropical Medicine, Belgium
- Sihanouk Hospital Center of HOPE
- University Hospital, Antwerp
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Short-term progression to advanced liver fibrosis
- Demographic characteristics
- Clinical characteristics
- (and 7 more...)
|
70 |
All |
18 Years and older (Adult, Older Adult) |
NCT02628691 |
HCV-Monitoring |
HCV-Monitoring |
December 17, 2015 |
July 12, 2017 |
July 12, 2017 |
December 11, 2015 |
August 23, 2017 |
|
- Sihanouk Hospital Center of HOPE (SHCH), Cambodia
Phnom Penh, Cambodia
|
|
| 5 |
NCT02653898 |
Unknown † |
Malaria Elimination Pilot Study in Military Forces in Cambodia |
- Malaria
- Parasitic Diseases
|
- Drug: DHA-PIP
- Drug: Primaquine
- Drug: Artesunate + Mefloquine
- Drug: Permethrin (Insecticide treated uniform)
|
Interventional
|
Phase 4 |
- Armed Forces Research Institute of Medical Sciences, Thailand
- National Center for Parasitology, Entomology, and Malaria Control (CNM)
- Ministry of National Defense, Royal Cambodian Armed Forces Department of Health
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- The absolute risk reduction based on the proportion of subjects remaining malaria-free at the end of 6 months between the study arms as diagnosed by PCR-corrected malaria microscopy
- Overall rate of sexual stage infections at Months 1 through 6 in each arm based on a combined endpoint of light microscopy and PCR analysis for detection of gametocyte maturity.
- Number of participants with abnormal lab values and/or Adverse Events that are related to the treatments in each arm
- (and 6 more...)
|
1200 |
All |
2 Years to 65 Years (Child, Adult, Older Adult) |
NCT02653898 |
WR2211 |
|
January 2016 |
August 2016 |
August 2016 |
January 13, 2016 |
January 29, 2016 |
|
- RCAF treatment facilities
Anlong Veng, Oddar Meancheay, Cambodia
|
|
| 6 |
NCT01593423 |
Completed |
Food Security and Nutrition in Rural Cambodia |
|
- Behavioral: plant-based Homestead Food Production
- Behavioral: Homestead Food Production plus small pond aquaculture
- Behavioral: a comparison group
|
Interventional
|
Not Applicable |
- University of British Columbia
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Change from Baseline in nutritionally related biochemical measures at 22 months
- 24-hour dietary recall
- Mid-upper arm circumference
- Household Food Security Scale
|
900 |
All |
Child, Adult, Older Adult |
NCT01593423 |
H12-00451 |
|
June 2012 |
August 2014 |
August 2014 |
May 8, 2012 |
November 17, 2016 |
|
- Rural Cambodia
Phnom Penh, Prey Veng, Cambodia
|
|
| 7 |
NCT02257762 |
Unknown † |
Efficacy of a Multiple Micronutrient-Fortified Lipid-Based Nutrient Supplement for Children Under Two in Cambodia |
|
- Dietary Supplement: LNS
- Dietary Supplement: Corn-soy blend ++ (CSB++)
- Dietary Supplement: Sprinkles
|
Interventional
|
Not Applicable |
- Institut de Recherche pour le Developpement, Cambodia
- UNICEF
- Department of Fisheries Post-harvest Technologies and Quality Control
- Institut de Recherche pour le Developpement, Cambodia
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Nutritional status
- Body composition
- Iron status
|
487 |
All |
6 Months to 12 Months (Child) |
NCT02257762 |
LNS-CAMB-INFANTS-EFF |
|
February 2016 |
October 2016 |
October 2016 |
October 6, 2014 |
September 15, 2016 |
|
- IRD Cambodia
Phnom Penh, Cambodia
|
|
| 8 |
NCT00479206 |
Completed |
Artemisinin Resistance in Cambodia |
|
|
Interventional
|
Not Applicable |
- Medical University of Vienna
- Global Emerging Infections Surveillance and Response System
- Armed Forces Research Institute of Medical Sciences, Thailand
- National Center for Parasitology, Entomology and Malaria Control
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Primary clinical outcome is cure (Adequate Clinical and Parasitological Response - ACPR as defined by WHO criteria) on Day 28.
- Secondary outcome measures are time until parasite, fever, and gametocyte clearance (PCT, FCT, and GCT).
|
|
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT00479206 |
WRAIR #1296
HSRRB A-13922 |
|
October 2006 |
|
February 2007 |
May 28, 2007 |
April 30, 2008 |
|
- Tasanh Health Center
Tasanh, Batambang, Cambodia
|
|
| 9 |
NCT02612545 |
Completed |
Efficacy, Safety, and Tolerability of Dihydroartemisinin-piperaquine + Mefloquine Compared to Dihydroartemisinin-piperaquine or Artesunate-mefloquine in Patients With Uncomplicated Falciparum Malaria in Cambodia |
|
- Drug: Dihydroartemisinin-piperaquine (DHA-PPQ)
- Drug: Mefloquine (MQ)
|
Interventional
|
Phase 1 |
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Compare the efficacy of TACT versus ACT, as defined by an adequate clinical and parasitological response (ACPR), defined as: absence of parasitemia on Day 42 (detected by blood smear, not PCR), irrespective of tympanic temperature, in subjects w...
- Compare parasite and fever clearance rates/times following TACT versus ACT
- Compare the safety and tolerability of TACT versus ACT
- Compare ECG QTc prolongation following TACT versus ACT
|
216 |
All |
2 Years to 65 Years (Child, Adult, Older Adult) |
NCT02612545 |
999916023
16-I-N023 |
|
November 20, 2015 |
October 12, 2018 |
October 12, 2018 |
November 24, 2015 |
October 17, 2018 |
|
- National Center for Parasitology, Entomology, and Malaria Controk, Ministry of H
Phnom Penh, Cambodia
|
|
| 10 |
NCT02118090 |
Completed |
Assessment of Plasmodium Vivax Chloroquine Resistance in Cambodia: |
|
- Drug: Chloroquine sulfate
- Drug: DHA-PP
|
Interventional
|
Phase 4 |
- Institut Pasteur, Cambodia
- National Institute of Allergy and Infectious Diseases (NIAID)
- Institut Pasteur, Cambodia
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Number of patients with P. vivax CQ resistant parasite
- Number of isolates characterized by whole genome sequencing and multiple Single Nucleotide Polymorphisms Bar Code
|
73 |
All |
15 Years and older (Child, Adult, Older Adult) |
NCT02118090 |
IPC_Pv_CQR_RTK
R01AI103228 |
CRePViCam |
May 2014 |
December 2014 |
March 2015 |
April 21, 2014 |
March 24, 2015 |
|
- Provincial Hospital
Ban Lung, Rattanakiri, Cambodia
|
|
| 11 |
NCT01240603 |
Completed |
Plasmodium Falciparum Clearance Rates in Response to Artesunate in Eastern Cambodia |
|
|
Observational
|
|
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Centre for Parasitology, Entomology and Malaria Control, Cambodia
- National Institutes of Health Clinical Center (CC)
|
NIH / Other |
- Time Perspective: Prospective
|
|
415 |
All |
1 Year and older (Child, Adult, Older Adult) |
NCT01240603 |
999911017
11-I-N017 |
|
October 24, 2010 |
|
September 11, 2013 |
November 15, 2010 |
April 5, 2018 |
|
- National Center for Parasitology, Entomology, and Malaria Controk, Ministry of H
Phnom Penh, Cambodia
|
|
| 12 |
NCT02297477 |
Active, not recruiting |
The ASAP Study - Therapeutic Efficacy of Atovaquone-proguanil vs. Artesunate-atovaquone-proguanil in Cambodia |
|
- Drug: atovaquone-proguanil
- Drug: artesunate-atovaquone-proguanil
|
Interventional
|
Phase 4 |
- Armed Forces Research Institute of Medical Sciences, Thailand
- National Centre for Parasitology, Entomology and Malaria Control, Cambodia
- Naval Medical Research Center, Asia (NMRC-A)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Efficacy at 42 days (with 95% confidence intervals) for AP with and without artesunate for uncomplicated P. falciparum diagnosed by positive PCR-corrected malaria microscopy.
- Efficacy at 28 days (with 95% confidence intervals) for atovaquone-proguanil and artesunate-atovaquone-proguanil for uncomplicated P. falciparum diagnosed by positive PCR-corrected malaria microscopy.
- Rates of sexual stage infections at days 1, 4, week 1 and week 2 based on a combined endpoint of light microscopy and PCR analysis for detection of gametocyte maturity.
- Comparative rates, duration and intensity of treatment-related adverse drug events, and total adverse events in each treatment group.
|
205 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT02297477 |
WR2115 |
ASAP |
December 2014 |
December 2015 |
February 2019 |
November 21, 2014 |
February 13, 2018 |
|
- Anlong Veng Referral Hospital
Anlong Veng, Oddar Meancheay, Cambodia
|
|
| 13 |
NCT02481375 |
Completed
Has Results |
Is Iron Deficiency the Cause of Anemia Among Women in Cambodia? |
- Anemia
- Iron Deficiency
- Hemoglobin Disorder
- (and 2 more...)
|
- Dietary Supplement: Multiple micronutrients
- Dietary Supplement: Iron
- Dietary Supplement: Placebo
|
Interventional
|
Not Applicable |
- University of British Columbia
- Micronutrient Initiative
- DSM Nutritional Products, Inc.
- (and 3 more...)
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Diagnostic
|
- Marginal Means (95% CI)
- Ferritin Response
- Composite Outcome Measure: Comparison of Multiple Biomarkers (Ferritin, sTfR, Reticulocyte Count, Hepcidin) Using the Area Under the Curve Analyses (Sensitivity and Specificity) to Indicate Responsiveness to Iron Therapy
|
809 |
Female |
18 Years to 45 Years (Adult) |
NCT02481375 |
H15-00933 |
|
July 2015 |
January 2016 |
January 2016 |
June 25, 2015 |
October 24, 2018 |
October 24, 2018 |
- Kampong Chhnang province
Kampong Chhnang, Kampong Chhnang Province, Cambodia
|
|
| 14 |
NCT01706419 |
Completed |
Fortified Rice for School Children in Cambodia |
|
- Dietary Supplement: Fortified rice cold extruded kernel
- Dietary Supplement: fortified rice warm extruded kernel
- Dietary Supplement: fortiified rice hot extruded kernel
|
Interventional
|
Not Applicable |
- Institut de Recherche pour le Developpement
- Department of Fisheries Post-harvest Technologies and Quality Control
- World Food Program Cambodia
- PATH
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Anthropometry
- Micronutrient status
- Cognition
- (and 4 more...)
|
9500 |
All |
6 Years to 14 Years (Child) |
NCT01706419 |
FORISCA |
FORISCA |
October 2012 |
July 2013 |
December 2014 |
October 15, 2012 |
December 18, 2014 |
|
- Department of Fisheries Post-harvest Technologies and Quality Control, Fisheries Administration
Phnom Penh, Cambodia
|
|
| 15 |
NCT01835574 |
Completed |
Cambodia Integrated HIV and Drug Prevention Implementation Program |
|
- Behavioral: Conditional cash transfer and cognitive-behavioral aftercare
|
Interventional
|
Not Applicable |
- University of California, San Francisco
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Sexual risk
- Amphetamine type stimulant use (ATS)
- Sexual risk 2
- (and 5 more...)
|
1198 |
Female |
18 Years and older (Adult, Older Adult) |
NCT01835574 |
1R01DA033672 |
CIPI |
April 2013 |
December 2016 |
December 2016 |
April 19, 2013 |
May 23, 2017 |
|
- Family Health International
Phnom Penh, Cambodia
|
|
| 16 |
NCT01736319 |
Completed |
Artemisinin-resistant Malaria in Cambodia |
- Plasmodium Falciparum Malaria
|
|
Observational
|
|
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Time Perspective: Prospective
|
|
561 |
All |
2 Years to 65 Years (Child, Adult, Older Adult) |
NCT01736319 |
999912163
12-I-N163 |
|
June 26, 2012 |
|
April 6, 2016 |
November 29, 2012 |
June 1, 2018 |
|
- National Center for Parasitology, Entomology, and Malaria Controk, Ministry of H
Phnom Penh, Cambodia
|
|
| 17 |
NCT03616288 |
Not yet recruiting |
Trial of Thiamine Supplementation in Cambodia |
|
- Dietary Supplement: thiamine (as thiamine hydrochloride)
|
Interventional
|
Not Applicable |
- Mount Saint Vincent University
- Sackler Institute for Nutrition Science at the New York Academy of Sciences
- Bill and Melinda Gates Foundation
- (and 6 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Prevention
|
- Human milk total thiamine concentration
|
320 |
Female |
18 Years to 45 Years (Adult) |
NCT03616288 |
MSVUREB2017-141
112NECHR |
|
September 2018 |
September 2019 |
August 2020 |
August 6, 2018 |
August 7, 2018 |
|
- Helen Keller International
Kampong Thom, Kapmong Thom Province, Cambodia
|
|
| 18 |
NCT00493363 |
Completed |
Clinical Investigation of In-vivo Susceptibility of P.Falciparum to Artesunate in Western Cambodia |
|
- Drug: Artesunate
- Drug: Artesunate + Mefloquine
|
Interventional
|
Not Applicable |
- University of Oxford
- World Health Organization
- NCHADS - Ministry of Health of Cambodia
- (and 4 more...)
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- parasite clearance times in relation to artesunate/DHA plasma concentrations (PK-PD)
- 56 day cure rates, in vitro sensitivity, molecular markers of drug resistance
|
40 |
All |
6 Years and older (Child, Adult, Older Adult) |
NCT00493363 |
1-Dondorp |
|
June 2007 |
December 2009 |
December 2009 |
June 28, 2007 |
May 4, 2018 |
|
- Pailin Referal Hospital
Pailin, Cambodia
|
|
| 19 |
NCT00532181 |
Unknown † |
Micro-Health Insurance in Cambodia |
- Health Insurance Sale
- Health Utilization
- Asset Sales, Investment and Saving Behaviors
|
- Behavioral: Savings Behavior and Consumer's Approach to Risk
|
Interventional
|
Early Phase 1 |
- University of California, Berkeley
- French Development Agency
- United States Agency for International Development (USAID)
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Prevention
|
- Better Understand Health Utilization Behavior in Cambodia
- Better Understand asset sales, investment and saving behaviors
|
|
All |
Child, Adult, Older Adult |
NCT00532181 |
CPHS Protocol 2007-3-48 |
|
April 2008 |
|
December 2011 |
September 20, 2007 |
September 20, 2007 |
|
- Sky Health Insurance
Phenom Phen, Cambodia
|
|
| 20 |
NCT03534245 |
Recruiting |
Investigating Vector-Borne Determinants of Aedes Transmitted Arboviral Infections in Cambodia: An Observational Longitudinal Cohort Study in Children |
|
|
Observational
|
|
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Prevalence of symptomatic and inapparent dengue infection (serotypes 1-4) as detected semiannually via ELISA assay (binary outcome present/absent) over a three-year period in Kampong Speu in children aged 2-9 years old
- Prevalence of Aedes aegypti salivary gland homogenate reactivity as detected by ELISA assay (binary outcome present/absent) during wet and dry seasons over a three-year period in Kampong Speu in children aged 2-9 years old
- Positive RT-PCR result for diagnosis of dengue, chikungunya, and Zika viruses (or IgM capture ELISAs for dengue as needed)
- (and 3 more...)
|
1200 |
All |
2 Years to 9 Years (Child) |
NCT03534245 |
999918100
18-I-N100 |
|
February 25, 2019 |
September 30, 2021 |
August 31, 2022 |
May 23, 2018 |
February 20, 2019 |
|
- Kampong Speu Referral Hospital
Chbar Mon, Kampong Speu, Cambodia
|
|
| 21 |
NCT00722150 |
Completed |
Artemisinin Resistance in Cambodia II |
|
|
Interventional
|
Not Applicable |
- Armed Forces Research Institute of Medical Sciences, Thailand
- World Health Organization
- Bill and Melinda Gates Foundation
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Primary clinical outcome is cure (Adequate Clinical and Parasitological Response - ACPR as defined by WHO criteria) on Day 28 and 42
- Safety and tolerability of oral artesunate
- Secondary outcome measures are time until parasite, fever, and gametocyte clearance (PCT, FCT, and GCT).
|
143 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT00722150 |
WRAIR 1396
HSRRB number A-14479
WHO RPC252 |
ARC II |
July 2008 |
August 2009 |
August 2009 |
July 25, 2008 |
January 25, 2011 |
|
- Tasanh Health Center
Sam Lot District, Battambang, Cambodia
|
|
| 22 |
NCT00078182 |
Withdrawn |
Daily Tenofovir DF to Prevent HIV Infection Among Sex Workers in Cambodia |
- HIV Infections
- HIV Seronegativity
|
|
Interventional
|
Phase 2
Phase 3 |
- National Institute of Allergy and Infectious Diseases (NIAID)
- NCHADS - Ministry of Health of Cambodia
- Kirby Institute
|
NIH / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Prevention
|
|
0 |
Female |
18 Years and older (Adult, Older Adult) |
NCT00078182 |
1U01AI054241-01 |
|
|
|
|
February 20, 2004 |
December 14, 2016 |
|
- NCAHDS
Phnom Penh, Cambodia
|
|
| 23 |
NCT00341003 |
Completed |
Severe Malaria and Anti-malarial Drug Resistance in Cambodia |
- Severe Malaria
- Malaria
- Antimalarial Drug Resistance
|
|
Observational
|
|
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Institutes of Health Clinical Center (CC)
|
NIH |
|
|
2090 |
All |
Child, Adult, Older Adult |
NCT00341003 |
999905210
05-I-N210 |
|
July 22, 2005 |
|
January 14, 2011 |
June 21, 2006 |
July 2, 2017 |
|
- Pursat Regional Health Center
Pursat, Cambodia
|
|
| 24 |
NCT03602690 |
Recruiting |
Evaluation of Third-line cART Regimen in Cambodia (3DICAM) |
|
- Drug: Dolutegravir + Darunavir/ritonavir + optimized NRTI
|
Interventional
|
Phase 2 |
- French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Virological effectiveness at 6 months
- Virological effectiveness at 12 months
- Incidence of adverse events (safety)
- (and 3 more...)
|
54 |
All |
15 Years and older (Child, Adult, Older Adult) |
NCT03602690 |
ANRS 12374 3DICAM |
|
October 4, 2018 |
October 3, 2020 |
October 3, 2020 |
July 27, 2018 |
November 14, 2018 |
|
- NCHADS
Phnom Penh, Cambodia
|
|
| 25 |
NCT02341586 |
Completed |
Lucky Iron Fish Home Fortification of Iron |
- Anemia
- Anemia, Iron-Deficiency
- Hemoglobinopathies
|
- Other: Lucky Iron Fish - home fortification system
- Dietary Supplement: 18 mg elemental iron
- Other: Nutrition Education
|
Interventional
|
Not Applicable |
- University of British Columbia
- NCHADS - Ministry of Health of Cambodia
- University of Guelph
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- hemoglobin concentration at endline
- Change in ferritin concentration
- Number of women in Preah Vihear, Cambodia with a genetic hemoglobin disorder
- (and 2 more...)
|
340 |
Female |
18 Years to 49 Years (Adult) |
NCT02341586 |
H14-02551 |
|
April 2015 |
May 2016 |
May 2016 |
January 19, 2015 |
March 16, 2018 |
|
- Rovieng Health Centre
Rovieng, Preah Vihear, Cambodia
|
|
| 26 |
NCT03331952 |
Active, not recruiting |
A Study of Streptococcus Pneumonia Colonisation and Invasive Disease in Cambodian Children |
|
- Other: Prospective study
- Other: Cross-sectional surveys
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Invasive pneumococcal disease hospitalisation rates
- Characteristics of invasive S. pneumoniae isolates in children <5 years of age admitted to Angkor Hospital for Children, in relation to national introduction of PCV13 in Cambodia
- Changes in pneumonia (both clinical and radiologic) hospitalisation rates in children <5 years of age, in relation to national introduction of PCV13 in Cambodia
- (and 5 more...)
|
4000 |
All |
up to 59 Months (Child) |
NCT03331952 |
COMRU1501 |
PCV |
August 3, 2015 |
August 31, 2018 |
June 30, 2019 |
November 6, 2017 |
January 11, 2019 |
|
- Angkor Hospital for Children
Siem Reap, Cambodia
|
|
| 27 |
NCT01624337 |
Terminated |
Malaria Prevention Cambodia |
|
- Drug: DHA-piperaquine
- Drug: placebo
|
Interventional
|
Not Applicable |
- Armed Forces Research Institute of Medical Sciences, Thailand
- National Centre for Parasitology, Entomology and Malaria Control, Cambodia
- Royal Cambodian Armed Forces
- United States Army Medical Materiel Development Activity
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- Protective efficacy
- Cardiac safety of piperaquine as determined by QT interval prolongation
|
231 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT01624337 |
WRAIR # 1849
A-17057 |
MPC |
May 2012 |
August 2014 |
June 2015 |
June 20, 2012 |
July 12, 2016 |
|
- Anlong Veng Referral Hospital
Anlong Veng, Oddar Meancheay, Cambodia
|
|
| 28 |
NCT02221063 |
Completed |
Thiamin Fortified Fish Sauce as a Means of Combating Infantile Beriberi in Rural Cambodia |
|
- Other: Thiamin fortified fish sauce (low concentration)
- Other: Thiamin fortified fish sauce (higher concentration)
- Other: Placebo fish sauce
|
Interventional
|
Phase 1 |
- University of British Columbia
- Helen Keller International
- Grand Challenges Canada
- (and 2 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Prevention
|
- Erythrocyte thiamin diphosphate
- Breast milk thiamin concentration
|
366 |
Female |
18 Years to 45 Years (Adult) |
NCT02221063 |
H14-00103
S6 0490-01-10 |
|
October 2014 |
April 2015 |
April 2016 |
August 20, 2014 |
May 25, 2016 |
|
- (Various Villages), Prey Veng, Cambodia
|
|
| 29 |
NCT02912975 |
Completed |
A Clinical Trial of Mirror Treatment for Phantom Pain |
- Phantom Limb Pain
- Complex Regional Pain Syndromes
|
- Other: Mirror treatment
- Other: Tactile treatment
|
Interventional
|
Not Applicable |
- Trauma Care Foundation, Norway
- University Hospital of North Norway
- NCHADS - Ministry of Health of Cambodia
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
|
45 |
All |
16 Months and older (Child, Adult, Older Adult) |
NCT02912975 |
975 905 055 |
|
March 2016 |
March 2017 |
July 15, 2017 |
September 23, 2016 |
October 18, 2017 |
|
- Trauma Care Foundation Cambodia
Battambang, Cambodia
|
|
| 30 |
NCT01413776 |
Completed |
Effects of a Fortified Dietary Supplement for Pregnant Women on Maternal and Newborn Outcomes in Kampong Chhnang Province, Cambodia |
- Maternal and Newborn Health
|
- Dietary Supplement: Corn Soya Blend+
|
Interventional
|
Not Applicable |
- University of British Columbia
- International Relief and Development
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Mean birth weight
- Mean gestational weight gain
- Mean maternal hemoglobin level
- Mean birth length and head circumference
|
547 |
Female |
18 Years to 49 Years (Adult) |
NCT01413776 |
H11-00801 |
|
August 2011 |
March 2013 |
March 2013 |
August 10, 2011 |
March 17, 2014 |
|
- 4 Health Centers
Kampong Chhnang, Cambodia
|
|
| 31 |
NCT00936767 |
Withdrawn |
Artemisone for the Treatment of Uncomplicated Falciparum Malaria in Western Cambodia |
- Uncomplicated Falciparum Malaria
|
- Drug: Artemisone/Mefloquine (AmiM3)
- Drug: Artesunate
|
Interventional
|
Phase 2
Phase 3 |
- University of Oxford
- Mahidol University
- Medicines for Malaria Venture
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Presence of light microscopic assessed peripheral blood parasitaemia at 72 hours after start of antimalarial treatment.
- Parasite clearance times (PCT, slope of the log clearance curve, PRR24, PRR48, PC50, PC90)
- Cure rate defined as clearance of asexual parasites without recrudescence within a 28 and 63-day period.
- (and 7 more...)
|
0 |
All |
16 Years and older (Child, Adult, Older Adult) |
NCT00936767 |
BAKMAL0901 |
AMOS |
October 2010 |
October 2010 |
October 2010 |
July 10, 2009 |
August 31, 2018 |
|
- Pailin Hospital
Pailin, Cambodia
|
|
| 32 |
NCT02907424 |
Active, not recruiting |
Comparison of a Locally Produced RUTF With a Commercial RUTF in the Treatment of SAM |
- Malnutrition
- Children
- Treatment
|
- Dietary Supplement: 2 months of treatment
|
Interventional
|
Not Applicable |
- Institut de Recherche pour le Developpement
- Ministry of Agriculture, Forestry and Fisheries Cambodia
- UNICEF
|
Other |
- Allocation: Randomized
- Intervention Model: Factorial Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- weight gain
- body composition
- Fatty Acid composition
|
120 |
All |
6 Months to 5 Years (Child) |
NCT02907424 |
IRD_UNICEF_DFPTQ_SAM |
FLNS_SAM |
April 1, 2016 |
January 15, 2017 |
May 2019 |
September 20, 2016 |
May 16, 2018 |
|
- Department of Fisheries Post-harvest Technologies and Quality Control, Fisheries Administration
Phnom Penh, Cambodia
|
|
| 33 |
NCT02253719 |
Completed |
Cervical Cancer Screening in HIV Positive and Negative Women in Cambodia |
- Cervical Neoplasia
- Cervical Cancer
|
- Procedure: cryotherapy, further biopsy, LEEP, surgery as indicated
|
Observational
|
|
- Sihanouk Hospital Center of HOPE
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Prevalence of cervical neoplasia in HIV positive women
- Prevalence of cervical neoplasia in HIV negative women
- Treatment of HIV positive women who screen as positive
- Treatment of HIV negative women who screen as positive
|
1000 |
Female |
30 Years to 49 Years (Adult) |
NCT02253719 |
SHCH-Cervical Screening-VIA |
|
October 2014 |
September 2015 |
September 2015 |
October 1, 2014 |
October 7, 2015 |
|
- Sihanouk Hospital, St. 134, Sangkat Vealvong, Khan 7 Makara
Phnom Pehn, Cambodia
|
|
| 34 |
NCT02271737 |
Unknown † |
Newborn Infection Control and Care Initiative for Health Facilities to Accelerate Reduction of Newborn Mortality |
|
- Behavioral: Training HC/VHSG, Health Education, and Supportive Supervision
|
Interventional
|
Not Applicable |
- National Institute of Public Health, Cambodia
- Tulane University School of Public Health and Tropical Medicine
- United States Agency for International Development (USAID)
- National Institute of Public Health, Cambodia
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- % of mothers who know at last 3 danger signs
- % of VHSG who know 6 danger signs
- % of families who seek care from an appropriate facility
- (and 11 more...)
|
1938 |
Female |
18 Years and older (Adult, Older Adult) |
NCT02271737 |
15 |
NICCI |
February 2015 |
December 2016 |
June 2017 |
October 22, 2014 |
June 12, 2015 |
|
- Selected Health Centers and Villages Under the Health Centers
Takeo, Takeo Province, Cambodia
|
|
| 35 |
NCT00263497 |
Unknown † |
Temporary Prosthesis in Traumatic Below-knee Amputation |
|
- Device: Temporary tuber-ischii bearing prosthesis
|
Interventional
|
Not Applicable |
- University Hospital of North Norway
- Medical University of Joenkoeping, Sweden
- NCHADS - Ministry of Health of Cambodia
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Pain: Patient-rated
- Pain: clinical exam rated
- Function: patient-rated
- (and 2 more...)
|
20 |
All |
15 Years to 55 Years (Child, Adult) |
NCT00263497 |
KHM1030375 |
|
March 2006 |
October 2012 |
December 2012 |
December 8, 2005 |
May 14, 2012 |
|
- Trauma Care Foundation Cambodia
Battambang, Cambodia
|
|
| 36 |
NCT03399058 |
Recruiting |
Innovative Nutrition and mHealth Evidence Building Project |
- Underweight Children Aged 6-23 Month Old (WAZ < -1)
|
- Other: Group 1 5+5+5 (Control)
- Behavioral: Group 2: 5+5+5 & PDH
- Behavioral: Group 3: 5+5+5 & PDH lite+mHealth
|
Interventional
|
Not Applicable |
- National Institute of Public Health, Cambodia
- World Vision International
- World Vision, Hong Kong
- (and 3 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change in prevalence of underweight children over time
- Change in mean of weight (grams) over time
- Change in percentage of caregivers correctly answering questions on child feeding, hygiene, health-seeking and caring practices over time
- (and 3 more...)
|
840 |
All |
Child, Adult, Older Adult |
NCT03399058 |
156NECHR |
|
November 27, 2017 |
March 30, 2020 |
March 30, 2020 |
January 16, 2018 |
January 18, 2018 |
|
- ADP Samrong Tong 2
Kampong Speu, Kamong Speu, Cambodia - ADP Boribor 2
Kampong Chhnang, Cambodia - ADP Rolea Phaea
Kampong Chhnang, Cambodia
|
|
| 37 |
NCT01849640 |
Suspended |
Antimalarial Drug Resistance With Assessment of Transmission Blocking Activity |
- Uncomplicated Plasmodium Falciparum Malaria
|
- Drug: DHA-piperaquine and Primaquine
|
Interventional
|
Not Applicable |
- David Saunders
- National Centre for Parasitology, Entomology and Malaria Control, Cambodia
- Royal Cambodian Armed Forces
- (and 2 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Clinical efficacy of DP
- Efficacy of Primaquine to treat sexual stage gametocyte infection and prevent transmission of P. falciparum gametocytes to mosquitoes.
|
150 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT01849640 |
WRAIR#1877
HRPO Log Number A-17145 |
|
December 2012 |
December 2014 |
June 2016 |
May 8, 2013 |
July 15, 2015 |
|
- Anlong Veng Referral Hospital
Anlong Veng, Oddormean Chey, Cambodia
|
|
| 38 |
NCT03726593 |
Recruiting |
Drug Combinations of Atovaquone-Proguanil (AP) With ACT |
- Plasmodium Falciparum Malaria (Drug Resistant)
|
- Drug: Artesunate and Pyronaridine
- Drug: Atovaquone Proguanil and Artesunate Pyronaridine
- Drug: Atovaquone Proguanil and Artesunate Mefloquine
|
Interventional
|
Phase 4 |
- Armed Forces Research Institute of Medical Sciences, Thailand
- National Center for Parasitology, Entomology, and Malaria Control (CNM)
- Naval Medical Research Unit-2 (NAMRU-2)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- 42-day polymerase chain reaction (PCR) corrected adequate clinical and parasitological response (ACPR), following treatment with ASPY and new drug combinations (AP+ACTs).
- Prevalence of molecular markers of drug resistance
- Drug susceptibility testing of parasite isolates against standard antimalarial drugs
- (and 13 more...)
|
252 |
All |
18 Years to 70 Years (Adult, Older Adult) |
NCT03726593 |
WR2530 |
APACT |
October 4, 2018 |
September 30, 2020 |
June 30, 2021 |
October 31, 2018 |
November 2, 2018 |
|
- Kratie Referral Hospital
Kratie, Cambodia - Anlong Veng Referral Hospital
Ânlóng Vêng, Cambodia
|
|
| 39 |
NCT00663546 |
Completed |
Malaria Studies in Cambodia |
|
|
Observational
|
|
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Institutes of Health Clinical Center (CC)
|
NIH |
- Time Perspective: Prospective
|
|
1978 |
All |
up to 100 Years (Child, Adult, Older Adult) |
NCT00663546 |
999908094
08-I-N094 |
|
March 24, 2008 |
|
December 5, 2013 |
April 22, 2008 |
August 20, 2018 |
|
- National Center for Parasitology, Entomology, and Malaria Controk, Ministry of H
Phnom Penh, Cambodia - Preah Vihear Referral Hospital
Preah Vihear Province, Cambodia - Ratanakiri Referral Hospital
Ratanakiri Province, Cambodia
|
|
| 40 |
NCT02434952 |
Completed |
Safety and Tolerability of Low Dose Primaquine |
- Malaria, Falciparum
- G6PD Deficiency
|
- Drug: Dihydroartemisinin piperaquine (DHA PP)
- Drug: Primaquine
|
Interventional
|
Phase 4 |
- Malaria Consortium
- National Centre for Parasitology, Entomology and Malaria Control, Cambodia
- Institute Pasteur, Cambodia
- (and 2 more...)
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Haemoglobin concentration
- Determine G6PD enzyme activity
- Assess usefulness of field adapted WHO haemoglobin colour card vs. Hemocue
- (and 17 more...)
|
109 |
All |
1 Year and older (Child, Adult, Older Adult) |
NCT02434952 |
015NECHR |
|
October 2014 |
July 2016 |
|
May 6, 2015 |
August 23, 2016 |
|
- Ratanakiri Provincial Hospital
Ratanakiri, Cambodia
|
|
| 41 |
NCT02389439 |
Completed |
Efficacy and Safety of Pyronaridine-artesunate for the Treatment in Uncomplicated Falciparum Malaria |
|
- Drug: Pyronaridine-artesunate
|
Interventional
|
Phase 2 |
- University of Oxford
- NCHADS - Ministry of Health of Cambodia
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- result of PCR
- hepatic biological values
- eosinophil count
- (and 8 more...)
|
123 |
All |
7 Years and older (Child, Adult, Older Adult) |
NCT02389439 |
Cambodia1 |
|
March 1, 2015 |
December 1, 2015 |
June 1, 2016 |
March 17, 2015 |
September 20, 2018 |
|
- Tasanh Health Centre, Battambang
Battambang, Cambodia - Referral hospital (Pailin)
Pailin, Cambodia - Promoy Health Centre (Pursat)
Pursat), Cambodia
|
|
| 42 |
NCT01823861 |
Unknown † |
Mobile Technology for Improved Family Planning |
- Contraception
- Post-abortion Family Planning
- mHealth
|
- Behavioral: Mobile phone-based intervention
|
Interventional
|
Not Applicable |
- Marie Stopes International
- London School of Hygiene and Tropical Medicine
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Use of a reliable contraceptive method at four-months post-abortion
- Pregnancy
- Repeat abortion
- Contraceptive discontinuation
|
500 |
Female |
18 Years and older (Adult, Older Adult) |
NCT01823861 |
MarieStopes |
MOTIF |
May 2013 |
September 2014 |
December 2014 |
April 4, 2013 |
May 28, 2014 |
|
- Marie Stopes International
Phnom Penh, Cambodia
|
|
| 43 |
NCT01280162 |
Completed |
Malaria Active Epidemiology and Treatment Study |
|
- Drug: Dihydroartemisinin piperaquine
|
Interventional
|
Not Applicable |
- Armed Forces Research Institute of Medical Sciences, Thailand
- United States Army Medical Materiel Development Activity
|
Other / U.S. Fed |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
|
222 |
All |
18 Years to 65 Years (Adult, Older Adult) |
NCT01280162 |
WRAIR # 1737
HRPO Log Number A-16251 |
|
September 2010 |
February 2011 |
December 2012 |
January 20, 2011 |
October 21, 2014 |
|
- Oddar Meancheay
Oddar Meancheay, Cambodia
|
|
| 44 |
NCT03355664 |
Recruiting |
Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and Vietnam |
|
|
Interventional
|
Phase 3 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- polymerase chain reaction corrected efficacy defined as adequate clinical and parasitological response (ACPR) by study arm
- 42-day polymerase chain reaction corrected efficacy according to site/geographic region
- Parasite clearance half-life
- (and 25 more...)
|
600 |
All |
2 Years to 65 Years (Child, Adult, Older Adult) |
NCT03355664 |
MAL17008 |
TACT-CV |
March 19, 2018 |
November 15, 2019 |
March 31, 2020 |
November 28, 2017 |
November 28, 2018 |
|
- Siem Pang Health Center
Siem Pang, Stung Treng, Cambodia - Pailin Referral Hospital
Pailin, Cambodia - Hospital for Tropical Diseases of Khanh Hoa,
Van Ninh, Khanh Hoa, Vietnam - Phuoc Long Hospital
Phuoc Long, Phuoc, Vietnam
|
|
| 45 |
NCT03632486 |
Recruiting |
Bedside Ultrasound Predicts Progression of Severity of Disease in Dengue Fever |
|
- Other: Bedside Ultrasound
|
Observational
|
|
- Timothy Gleeson
- Angkor Hospital for Children
- University of Massachusetts, Worcester
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Clinical Progression of disease
|
250 |
All |
up to 16 Years (Child) |
NCT03632486 |
H00003325 |
|
August 13, 2018 |
October 1, 2019 |
October 1, 2020 |
August 15, 2018 |
September 14, 2018 |
|
- Angkor Hospital for Children
Siem Reap, Cambodia
|
|
| 46 |
NCT02134652 |
Withdrawn |
Ability of Bedside Ultrasound to Predict Progression of Severity of Disease in Dengue Fever |
- Dengue
- Disease Progression
|
- Other: diagnostic bedside ultrasound
|
Observational
|
|
- University of Massachusetts, Worcester
|
Other |
- Time Perspective: Prospective
|
- Progression of Disease
- Clinical Care
|
0 |
All |
3 Months to 16 Years (Child) |
NCT02134652 |
EUS-3325 |
|
January 2015 |
June 2016 |
June 2016 |
May 9, 2014 |
June 11, 2015 |
|
- Angkor Hospital for Children
Siem Reap, Cambodia
|
|
| 47 |
NCT02413658 |
Unknown † |
Phenytoin in the Healing of Clean Surgical Wounds |
- Wound
- Re-Epithelialization
|
- Drug: Phenytoin
- Drug: Sugar solution
|
Interventional
|
Phase 2 |
- Children's Surgical Center, Cambodia
- Children's Surgical Center, Cambodia
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Percentage rate of re-epithelialization
- Appearance of infection
|
100 |
All |
up to 80 Years (Child, Adult, Older Adult) |
NCT02413658 |
1CSC2015 |
|
March 2015 |
April 2016 |
|
April 10, 2015 |
April 10, 2015 |
|
- Children's Surgical Centre
Phnom Penh, Cambodia
|
|
| 48 |
NCT02668406 |
Completed |
Study to Obtain Blood and Voided Urine Samples to Improve the Diagnosis of Melioidosis |
- Melioidosis
- Systemic Inflammatory Response Syndrome
- Suspected or Confirmed Bloodstream Infections
|
- Other: Venous blood sampling (2 timepoints) (Phase A and B)
- Other: Venous blood sampling (1 timepoint) (Phase A and B)
- Other: Voided urine sampling (first sample) (Phase A)
- Other: Voided urine sampling (second sample) (Phase A)
|
Observational
|
|
- Institute of Tropical Medicine, Belgium
- Sihanouk Hospital Center of HOPE
- SRI International
|
Other / Industry |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- Clinical reference panel (blood)
- Clinical reference panel (urine)
|
4203 |
All |
18 Years and older (Adult, Older Adult) |
NCT02668406 |
Melioidosis |
|
February 2016 |
September 30, 2018 |
September 30, 2018 |
January 29, 2016 |
October 23, 2018 |
|
- HOPE Community Medical Center
Phnom Penh, Cambodia - Sihanouk Hospital Center of HOPE (SHCH), Cambodia
Phnom Penh, Cambodia
|
|
| 49 |
NCT01663831 |
Completed |
Repellents as Added Control Measure to Long Lasting Insecticidal Nets |
|
- Other: Mosquito topical repellent
|
Interventional
|
Not Applicable |
- Institute of Tropical Medicine, Belgium
- NCHADS - Ministry of Health of Cambodia
- Institut Pasteur
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Change from baseline in malaria prevalence at 6 months
- Malaria incidence
|
40000 |
All |
2 Years and older (Child, Adult, Older Adult) |
NCT01663831 |
OPP1032354 |
MalaResT |
May 2012 |
December 2013 |
December 2013 |
August 13, 2012 |
February 3, 2014 |
|
- Banlung, Ratanakiri, Cambodia
|
|
| 50 |
NCT03727308 |
Recruiting |
Clinic-based Versus Self-use of Medical Abortion Pills |
- Abortion, Induced
- Pregnancy Trimester, First
- Misoprostol
- Mifepristone
|
- Behavioral: Medical abortion pills sourced from pharmacies
- Behavioral: Medical abortion pills sourced from health clinics
|
Observational
|
|
- Ipas
- University of Health Science, Phnom Penh, Cambodia
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Need for additional treatment to complete abortion
- Serious complications/ morbidity
|
4000 |
Female |
15 Years and older (Child, Adult, Older Adult) |
NCT03727308 |
0916 NECHR |
MOC |
May 30, 2018 |
March 30, 2019 |
January 30, 2020 |
November 1, 2018 |
November 1, 2018 |
|
- University of Health Sciences
Phnom Penh, Cambodia
|
|
| 51 |
NCT02937779 |
Recruiting |
Tenofovir As Prevention Of Hepatitis b Mother-to-child Transmission |
- Hepatitis B Chronic Infection
- Pregnancy
|
- Drug: Tenofovir disoproxil fumarate
- Device: Rapid tests HBe Ag
|
Interventional
|
Phase 4 |
- French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Proportion of active HBV infection in new-born at 6 months of life estimated by HBs Ag positivity
- Process and acceptability of the screening phase : Proportion of women with screening proposed among those eligible in antenatal consultation (ANC)
- Process and acceptability of the screening phase: Proportion of women with a done screening among those to whom screening was proposed
- (and 2 more...)
|
933 |
Female |
18 Years to 50 Years (Adult) |
NCT02937779 |
ANRS 12345 |
TA-PROHM |
October 4, 2017 |
October 2019 |
December 2019 |
October 19, 2016 |
January 23, 2018 |
|
- Kampong Cham Provincial Hospital
Kampong Cham, Cambodia - Calmette Hospital
Phnom Penh, Cambodia - National Mother and Child Health Center
Phnom Penh, Cambodia
|
|
| 52 |
NCT01864057 |
Completed |
Pharmacokinetics of Thiamine in Breastfeeding Mothers and Infants |
|
- Drug: thiamine hydrochloride 100 mg
|
Interventional
|
Phase 1 |
- Mayo Clinic
- Eastern Mennonite Missions
- ARUP Laboratories
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Basic Science
|
- blood thiamine concentration
- breast milk thiamine concentration
|
24 |
Female |
18 Years and older (Adult, Older Adult) |
NCT01864057 |
MCR 12-004047; NECHR 208 |
|
January 2012 |
July 2012 |
September 2012 |
May 29, 2013 |
May 29, 2013 |
|
- Mayo Clinic
Rochester, Minnesota, United States - Svai Chrum Clinic
Mesang District, Prey Veng, Cambodia
|
|
| 53 |
NCT00226434 |
Completed |
Early vs Late Introduction of Antiretroviral Therapy in HIV-infected Patients With Tuberculosis (ANRS 1295 CAMELIA) |
- HIV Infection
- Tuberculosis
|
- Procedure: Early antiretroviral treatment
- Procedure: Late antiretroviral treatment
|
Interventional
|
Phase 3 |
- French National Agency for Research on AIDS and Viral Hepatitis
- National Institutes of Health (NIH)
- French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
|
Other / NIH |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Survival rate
- Type, frequency and severity of Adverse Events that occur during the trial and to their potential relations with the drugs, HIV or TB infection
- Frequency of Immune Reconstitution Inflammatory Syndrome
- (and 8 more...)
|
661 |
All |
18 Years and older (Adult, Older Adult) |
NCT00226434 |
ANRS 1295 CAMELIA
CIPRA KH 001 |
|
January 2006 |
May 2010 |
May 2010 |
September 27, 2005 |
March 16, 2012 |
|
- Calmette Hospital
Phnom Penh, Cambodia - Khmero-Soviet Friendship Hospital
Phnom Penh, Cambodia - Siem Reap Referral Hospital
Siem Reap, Cambodia - (and 2 more...)
|
|
| 54 |
NCT01801618 |
Completed |
National Evaluation of PI-based 2nd Line Efficacy in Cambodia |
|
|
Observational
|
|
- French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
|
Other |
- Time Perspective: Cross-Sectional
|
- Prevalence of virological failure
- Prevalence of drug resistance
- Evaluation of individual risk factors associated with treatment failure
- Evaluation of structural risk factors associated with treatment failure
|
15001351 |
All |
18 Years and older (Adult, Older Adult) |
NCT01801618 |
ANRS12276 2PICAM |
|
February 2013 |
July 2014 |
December 2014 |
March 1, 2013 |
July 21, 2016 |
|
- Battambang Hospital
Battambang, Cambodia - Chey Chum Neah Hospital
Chey Chum Neah, Cambodia - Daun Keo Hospital
Daun Keo, Cambodia - (and 10 more...)
|
|
| 55 |
NCT01178736 |
Unknown † |
Early Detection of Cancers in Low Resource Countries |
- Breast Neoplasms
- Uterine Cervical Neoplasms
- Ovarian Neoplasms
- Endometrial Neoplasms
|
- Procedure: Breast Cancer Screening and Diagnosis
- Procedure: Cervical Cancer Screening and Diagnosis
- Procedure: Ovarian Cancer Screening and Diagnosis
- Procedure: Endometrial Cancer Screening and Diagnosis
|
Observational
|
|
- Woman's Cancer Foundation
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- The Effectiveness of an Innovative, Low-Cost Screening and Diagnostic Methodology
- Effectiveness of CBE and Ultrasonography for Breast Cancer Detection
|
36000 |
Female |
30 Years to 64 Years (Adult) |
NCT01178736 |
WCF-2011-BRA-IND-CAM |
|
March 2011 |
March 2014 |
March 2014 |
August 10, 2010 |
August 10, 2010 |
|
- Hospital de Cancer de Barretos
Sao Paolo, Brazil - Sihanouk Hospital Center of Hope, Hope Worldwide Cambodia
Phnom Penh, Cambodia - Manipal Healthcare Group
Goa, India
|
|
| 56 |
NCT01306383 |
Completed |
Solar Disinfection (SODIS) of Drinking Water for Use in Developing Countries or in Emergency Situations |
|
|
Interventional
|
Not Applicable |
- Royal College of Surgeons, Ireland
- ICROSS, Kenya
- International Water and Sanitation Development (IWSD), Zimbabwe
- CARE International - Cambodia (CIC), Cambodia
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Dysentery disease rate
- Diarrhoea disease rate
- Height and weight benefit
|
2400 |
All |
12 Months to 5 Years (Child) |
NCT01306383 |
SODISWATER EU 031650
SODIS Kenya, Zimbab, Cambodia |
SODISWATER |
June 2008 |
October 2009 |
May 2010 |
March 1, 2011 |
November 10, 2011 |
|
- CIC
Phnom Penh, Cambodia - ICROSS
Nairobi, Ngong Hills, Kenya - IWSD
Harare, Mount Pleasant, Zimbabwe
|
|
| 57 |
NCT01331811 |
Completed |
Improving Diagnosis of Tuberculosis in HIV Infected Children in Asia (Cambodia, Vietnam)and Africa (Burkina Faso, Cameroon) |
- HIV
- Tuberculosis
- Pediatrics
|
- Other: Development of a diagnosis algorithm
|
Interventional
|
Not Applicable |
- French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
- Institut Pasteur, Cambodia
- National Pediatric Hospital, Cambodia
- (and 13 more...)
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Tuberculosis diagnostic algorithm
- Evaluation of the QuantiFERON(R)-TB Gold In-Tube
- Comparison of two in-vitro IGRAs
- (and 6 more...)
|
441 |
All |
up to 13 Years (Child) |
NCT01331811 |
ANRS12229 PAANTHER 01 |
|
April 2011 |
March 2014 |
May 2014 |
April 8, 2011 |
August 5, 2015 |
|
- CHU Sourô Sanou
Bobo Dioulasso, Burkina Faso - National Pediatric Hospital
Phnom Penh, Cambodia - Angkor Hospital for Children
Siem Reap, Cambodia - (and 5 more...)
|
|
| 58 |
NCT02983487 |
Recruiting |
Pertussis Immunization Programs in Low Income Countries |
- Bordetella Pertussis, Whooping Cough
|
- Procedure: Nasopharyngeal sampling
- Procedure: Blood Sampling
|
Observational
|
|
- Institut Pasteur
- Institut Pasteur, Cambodia
- Institut Pasteur de Madagascar
- Agence de Médecine Préventive, France
|
Industry / Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Proportion of biologically confirmed cases of pertussis in patients under 6 months old admitted into hospital with clinical signs corresponding to whooping cough syndrome.
- Proportion of cases tested positive for B.Pertussis given by the presence of B. pertussis DNA in the nasopharyngeal sample or by the presence of an anti-pertussis toxin IgG level >100 IU/mL in the serum.
- Proportion of cases tested positive given by the presence of an anti-pertussis toxin IgG level >100 IU/mL in the serum.
- Estimation of the relative risk of the disease occurring in the contact patients based on their immunization status and age groups
|
3500 |
All |
Child, Adult, Older Adult |
NCT02983487 |
2015-055 |
PERILIC |
January 22, 2017 |
November 2019 |
November 2019 |
December 6, 2016 |
August 9, 2018 |
|
- Institut Pasteur of Cambodia
Phnom Penh, Cambodia - Institut Pasteur de Madagascar
Antananarivo, Madagascar - Agence de Médecine Préventive
Dapaong, Togo
|
|
| 59 |
NCT02406768 |
Completed |
A Sub-study of PREDICT Neurodevelopment Protocol |
- Neurocognitive Development
|
|
Observational
|
|
- The HIV Netherlands Australia Thailand Research Collaboration
- National Institute of Allergy and Infectious Diseases (NIAID)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- National Institute of Mental Health (NIMH)
|
Other / NIH |
- Observational Model: Case Control
- Time Perspective: Prospective
|
- neurodevelopment changes (composite of cognitive, fine motor and behavioral)
|
300 |
All |
1 Year to 15 Years (Child) |
NCT02406768 |
HIV-NAT 035.4 |
|
October 2010 |
August 2011 |
August 2011 |
April 2, 2015 |
April 2, 2015 |
|
- National Center for HIV/AIDS, Dermatology and STDs (NCHADS)
Phnom Penh, Cambodia - National Pediatric Hospital
Phnom Penh, Cambodia - Pediatric Infectious Diseases Unit Department of Pediatrics Faculty of Medicine Chulalongkorn University
Bangkok, Thailand - (and 7 more...)
|
|
| 60 |
NCT01766830 |
Completed |
Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever) |
- Visceral Leishmaniasis
- Human African Trypanosomiasis
- Enteric Fever
- (and 9 more...)
|
- Device: rk28 ICT
- Device: IT LEISH (rK39)
- Device: Immunochromatographic HAT test
- (and 7 more...)
|
Interventional
|
Not Applicable |
- University Hospital, Geneva
- Institute of Tropical Medicine, Belgium
- B.P. Koirala Institute of Health Sciences
- (and 3 more...)
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Prevalence of Visceral Leishmaniasis (VL), Human African Trypanosomiasis (HAT) and other Neglected Tropical Diseases (NTDs)
- Identification of clinical and laboratory diagnostic indicators
- Identification of reliable Rapid Diagnostic Tests (RDTs)
- (and 2 more...)
|
1927 |
All |
5 Years and older (Child, Adult, Older Adult) |
NCT01766830 |
WP2-01-FEV
260260 |
|
January 2013 |
October 2014 |
July 2016 |
January 11, 2013 |
October 27, 2016 |
|
- Sihanouk Hospital Center of HOPE
Phnom Penh, Cambodia - Reference Hospital Mosango and Kasay Health Centre
Mosango, Bandundu, Congo, The Democratic Republic of the - Institut National de Recherche Biomédicale
Kinshasa, Congo, The Democratic Republic of the - (and 4 more...)
|
|
| 61 |
NCT02689193 |
Active, not recruiting |
IDIS Project Work Package 2: Establishing a Biobank at ITM and Collaborating Centres |
- Salmonella Septicemia
- Salmonella Infections
- Fever
- (and 2 more...)
|
|
Observational
|
|
- Institute of Tropical Medicine, Belgium
- Sihanouk Hospital Center of HOPE
- Institut National de Recherche Biomédicale. Kinshasa, République Démocratique du Congo
- Vlaams Instituut voor Biotechnologie
|
Other |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- Detection of bacterial proteins through Selected Reaction Monitoring (SRM) measured in the unit m/z
- Quantification of bacterial proteins measured through Selected Reaction Monitoring (SRM) as ion counts
- Ranking of detected bacterial proteins based on detection per number of samples and on ion counts
- (and 3 more...)
|
2500 |
All |
2 Months and older (Child, Adult, Older Adult) |
NCT02689193 |
IDIS |
IDIS |
September 2014 |
August 2019 |
August 2019 |
February 23, 2016 |
August 28, 2018 |
|
- Institute of Tropical Medicine
Antwerp, Flandres, Belgium - Sihanouk Hospital Center of Hope (SHCH)
Phnom Penh, Cambodia - Institut National de Recherche Biomédicale
Kinshasa, Congo, The Democratic Republic of the
|
|
| 62 |
NCT01872702 |
Completed |
Targeted Chemo-elimination (TCE) of Malaria |
- Plasmodium Falciparum Malaria
|
- Drug: malaria elimination using DP and low-dose primaquine
|
Interventional
|
Not Applicable |
- University of Oxford
- Mahidol Oxford Tropical Medicine Research Unit
- National Centre for Parasitology, Entomology and Malaria Control, Cambodia
- (and 7 more...)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- prevalence of falciparum malaria measured by qPCR (quantitative real time polymerase chain reaction), 12 months after the first administration of treatment with dihydroartemisinin-piperaquine and primaquine. (1017-13 and 23-15)
- prevalence of falciparum malaria measured by qPCR (quantitative real time polymerase chain reaction), 12 months after the first administration of targeted malaria elimination (1015-13)
- prevalence of falciparum malaria measured by qPCR (quantitative real time polymerase chain reaction), 4 months after the first administration of target malaria-elimination (23-15)
- Safety and acceptability of targeted malaria elimination (1017-13 and 1015-13)
|
8000 |
All |
6 Months and older (Child, Adult, Older Adult) |
NCT01872702 |
BAKMAL1305 |
TME |
April 2013 |
July 2017 |
July 2017 |
June 7, 2013 |
August 10, 2017 |
|
- Pailin
Pailin, Cambodia - Savannakhet
Savannakhet, Lao People's Democratic Republic - Mahidol Oxford Clincal Research Unit, Myanmar
Rangoon, Myanmar - (and 2 more...)
|
|
| 63 |
NCT01350856 |
Completed |
Tracking Resistance to Artemisinin (TRAC) |
|
- Drug: Artesunate 2
- Drug: Artesunate 4
|
Interventional
|
Phase 4 |
- University of Oxford
- Mahidol University
- Worldwide Antimalarial Resistance Network
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Parasite clearance rate
- Parasite clearance time
- Parasite reduction rates and ratios
- (and 10 more...)
|
1700 |
All |
6 Months to 65 Years (Child, Adult, Older Adult) |
NCT01350856 |
BAKMAL1101 |
TRAC |
May 2011 |
April 2014 |
December 2014 |
May 10, 2011 |
June 1, 2015 |
|
- Ramu Upazila Health Complex
Cox's Bazaar, Bangladesh - Pailin General Hospital
Pailin, Cambodia - District Referral Hospital
Preah Vihear, Cambodia - (and 16 more...)
|
|
| 64 |
NCT03831906 |
Not yet recruiting
New |
TB-Speed Pneumonia |
- Tuberculosis
- Severe Pneumonia
|
- Diagnostic Test: Xpert MTB/RIF Ultra (Ultra)
|
Interventional
|
Not Applicable |
- Institut National de la Santé Et de la Recherche Médicale, France
- UNITAID
|
Other |
- Allocation: Randomized
- Intervention Model: Crossover Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- All-cause mortality 12 weeks after inclusion
- Number of children diagnosed with TB at 12 weeks
- • Proportion of children with TB treatment initiated at any time during follow-up
- (and 15 more...)
|
3780 |
All |
2 Months to 59 Months (Child) |
NCT03831906 |
C18-26 |
|
February 18, 2019 |
August 18, 2020 |
November 18, 2020 |
February 6, 2019 |
February 6, 2019 |
|
- Kampong Cham Provincial Referral Hospital
Kampong Cham, Cambodia - National Pediatric Hospital
Phnom Penh, Cambodia - Takeo Provincial Referral Hospital
Takeo, Cambodia - (and 12 more...)
|
|
| 65 |
NCT00334256 |
Completed |
Tenofovir/Emtricitabine for PMTCT in Africa and Asia (ANRS 12109 TEmAA) |
|
- Drug: Tenofovir (TDF)
- Drug: Emtricitabine (FTC)
|
Interventional
|
Phase 2 |
- French National Agency for Research on AIDS and Viral Hepatitis
- European and Developing Countries Clinical Trials Partnership (EDCTP)
- Gilead Sciences
|
Other / Industry |
- Allocation: Non-Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Pharmacokinetic parameters of TDF and FTC in the mother and child
- Safety of TDF + FTC in pregnant women
- Safety of TDF + FTC in children
- (and 3 more...)
|
72 |
Female |
18 Years and older (Adult, Older Adult) |
NCT00334256 |
ANRS 12109 TEmAA |
TEmAA |
October 2006 |
July 2009 |
December 2009 |
June 7, 2006 |
December 5, 2011 |
|
- Calmette Hospital
Phnom Penh, Cambodia - Centre de Prise en Charge et de Formation ACONDA
Abidjan, Côte D'Ivoire - PHRU
Soweto, South Africa
|
|
| 66 |
NCT01087099 |
Completed |
A Multinational Trial of the Efficacy of Albendazole Against Soil-transmitted Nematode Infections in Children |
- Infections With Soil-Transmitted Helminths (STH)
|
|
Interventional
|
Phase 4 |
- University Ghent
- World Health Organization
- George Washington University
- (and 3 more...)
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
|
1750 |
All |
6 Years to 14 Years (Child) |
NCT01087099 |
2008/322 |
WORMCON |
January 2009 |
December 2009 |
March 2010 |
March 15, 2010 |
August 2, 2011 |
|
- Instituto René Rachou, Fundação Oswaldo Cruz
Minas Gerais, Brazil - Institut Pasteur in Cambodia, Clinical Pathology Unit
Phnom Penh, Cambodia - Centre for Schistosomiasis and Parasitology, Faculty of Sciences, University of Yaoundé I
Yaounde, Cameroon - (and 4 more...)
|
|
| 67 |
NCT00234091 |
Completed |
When to Start Anti-HIV Drugs in Children Infected With HIV (The PREDICT Study) |
|
- Drug: Abacavir
- Drug: Efavirenz
- Drug: Lamivudine
- (and 4 more...)
|
Interventional
|
Phase 3 |
- National Institute of Allergy and Infectious Diseases (NIAID)
- Comprehensive International Program of Research on AIDS
|
NIH / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- AIDS-free survival
- Direct and indirect cost of treatment per patient
- Number and duration of hospitalizations
- (and 17 more...)
|
300 |
All |
1 Year to 12 Years (Child) |
NCT00234091 |
CIPRA TH001
PREDICT
10409 |
|
April 2006 |
September 2011 |
September 2011 |
October 6, 2005 |
December 4, 2013 |
|
- National Pediatric Hosp., Cambodia CIPRA CRS
Phnom Penh, Cambodia - Social Health Clinic, Cambodia CIPRA CRS
Phnom Penh, Cambodia - Hiv-Nat Cipra Crs
Pathumwan, Bangkok, Thailand - (and 6 more...)
|
|
| 68 |
NCT01550016 |
Completed |
International Research Consortium on Dengue Risk Assessment, Management, and Surveillance |
|
|
Observational
|
|
- University of Heidelberg Medical Center
- European Union
- University of Oxford
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Hospitalization or administration of IV fluid
- Development of severe disease
|
7411 |
All |
5 Years and older (Child, Adult, Older Adult) |
NCT01550016 |
281803 (EU FP7-HEALTH-2011) |
IDAMS |
October 2011 |
June 2016 |
October 2016 |
March 9, 2012 |
October 11, 2016 |
|
- International Centre for Diarrhoeal Diseases
Dhaka, Bangladesh - Fundacao Universidade Estadual do Ceara
Fortaleza, Brazil - Fundacao Oswaldo Cruz (FIOCRUZ)
Rio de Janeiro, Brazil - (and 6 more...)
|
|
| 69 |
NCT02057796 |
Active, not recruiting |
Systematic Empirical vs. Test-guided Anti-TB Treatment Impact in Severely Immunosuppressed HIV-infected Adults Initiating ART With CD4 Cell Counts <100/mm3 |
|
- Device: Xpert MTB/RIF®, Determine TB LAM, Chest X-ray
- Drug: ART (Atripla, Truvada, Efavirenz, Combivir)
- Drug: Rifampin, isoniazid, pyrazinamide, ethambutol
|
Interventional
|
Phase 4 |
- French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- All-cause mortality and incidence of invasive bacterial infections
- Incidence of confirmed/probable/possible TB
- Incidence of grade 3 or 4 adverse events
|
1050 |
All |
18 Years and older (Adult, Older Adult) |
NCT02057796 |
ANRS 12290 |
STATIS |
September 2014 |
November 2017 |
June 2018 |
February 7, 2014 |
July 12, 2017 |
|
- Sihanouk Hospital Center of Hope
Phnom Penh, Cambodia - CePReF Centre de Prise en charge de Recherche et de Formation
Abidjan, Yopougon, Côte D'Ivoire - ISS ImmunoSuppression Service
Mbarara, Uganda - Pham Ngoc Thach Hospital
Ho Chi Minh City, Vietnam
|
|
| 70 |
NCT03384498 |
Recruiting |
Malaria Genetic Surveillance |
|
|
Observational
|
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Annual maps and reports on the prevalence of drug resistance-linked genetic mutations in P. falciparum parasites in the Greater Mekong Subregion
- Allelic variations associated to drug resistance in P. falciparum at the locations surveyed
- Allelic variations associated to drug resistance in P. vivax at the locations surveyed
- (and 4 more...)
|
30000 |
All |
Child, Adult, Older Adult |
NCT03384498 |
BIOINF1602 |
|
October 2016 |
October 2019 |
December 2020 |
December 27, 2017 |
January 11, 2019 |
|
- National Centre for Malaria Control, Parasitology and Entomology (CNM)
Phnom Penh, Cambodia - Center of Malariology, Parasitology and Entomology
Vientiane, Lao People's Democratic Republic - Buntharik hospital
Ubon Ratchathani, Thailand - (and 2 more...)
|
|
| 71 |
NCT00440999 |
Completed |
Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria |
|
- Drug: Pyronaridine artesunate
- Drug: Chloroquine
|
Interventional
|
Phase 3 |
- Medicines for Malaria Venture
- Shin Poong Pharmaceuticals
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Treatment
|
- Cure rate on Day 14.
- Incidence of adverse events and of clinically significant laboratory results, ECG, vital signs or physical examination abnormalities.
- Cure rate on Days 21 and 28.
- (and 4 more...)
|
456 |
All |
3 Years to 60 Years (Child, Adult) |
NCT00440999 |
SP-C-006-06 |
|
March 2007 |
April 2008 |
September 2008 |
February 27, 2007 |
January 22, 2009 |
|
- Pailin Referral Hospital
Pailin, Pailin Province, Cambodia - Wentlock District Hospital
Mangalore, India - RSUD TC Hillers
Maumere, Nusa Tenggara Timur, Indonesia - (and 2 more...)
|
|
| 72 |
NCT01594931 |
Completed |
Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum Malaria |
- Plasmodium Falciparum Malaria
|
- Drug: pyronaridine/artesunate
|
Interventional
|
Phase 2 |
- Medicines for Malaria Venture
- Shin Poong Pharmaceutical Co. Ltd.
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double
- Primary Purpose: Treatment
|
- Cure rate on Day 28
- Safety
- Cure rate on Day 14
- (and 4 more...)
|
477 |
All |
15 Years to 60 Years (Child, Adult) |
NCT01594931 |
SP-C-002-05 |
|
July 2005 |
March 2006 |
April 2006 |
May 9, 2012 |
May 9, 2012 |
|
- Pailin General Hospital
Pailin, Cambodia - Farafenni Field Station, c/o MRC Laboratories
Faraffeni, Gambia - Bethesday Hospital
Tomohon, North Sulawesi, Indonesia - (and 3 more...)
|
|
| 73 |
NCT02453308 |
Completed |
A Study by the Tracking Resistance to Artemisinin Collaboration (TRAC) |
|
|
Interventional
|
Phase 2
Phase 3 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- PCR corrected efficacy defined as adequate clinical and parasitological response (ACPR)
- Parasite clearance half-life
- Parasite reduction rates and ratios at 24 and 48 hours assessed by microscopy
- (and 21 more...)
|
1110 |
All |
6 Months to 65 Years (Child, Adult, Older Adult) |
NCT02453308 |
BAKMAL1502 |
TRACII |
August 2015 |
March 2018 |
March 2018 |
May 25, 2015 |
May 9, 2018 |
|
- College of Medicine Chittagong
Ramu, Bangladesh - Pailin
Pailin, Cambodia - Preah Vihear
Preah Vihear, Cambodia - (and 17 more...)
|
|
| 74 |
NCT01379326 |
Completed |
Monitoring the Efficacy of Anthelmintics for the Treatment of Soil Transmitted Helminths P2 |
- Ascaris Lumbricoides
- Ascaris Suum
- Trichuris Trichiura
- (and 5 more...)
|
|
Interventional
|
Phase 4 |
- University Ghent
- Commonwealth Scientific and Industrial Research Organisation, Australia
- World Health Organization
- (and 11 more...)
|
Other / Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Reduction of fecal egg counts at 14 days post-intervention.
- Distribution of hookworms species.
|
250 |
All |
4 Years to 18 Years (Child, Adult) |
NCT01379326 |
2011/374 |
ConWorm |
December 2011 |
December 2012 |
December 2012 |
June 23, 2011 |
December 5, 2014 |
|
- Fundacion Huesped
Buenos Aires, Argentina - Commonwealth Scientific and Industrial Research Organisation
Brisbane, Australia - Queensland Institute for Medical Research, University of Queensland
Herston QLD, Australia - (and 6 more...)
|
|
| 75 |
NCT02968355 |
Recruiting |
Clinical Evaluation of the FilmArray® Global Fever (GF) Panel |
|
- Other: Observational study
|
Observational
|
|
- BioFire Defense LLC
- United States Department of Defense
- National Institute of Allergy and Infectious Diseases (NIAID)
|
Industry / U.S. Fed / NIH |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Clinical sensitivity and specificity of the FilmArray Global Fever (GF) Panel
|
1500 |
All |
Child, Adult, Older Adult |
NCT02968355 |
SDY-017266
HHSN272201600002C
W911QY-13-D-0080 |
|
March 26, 2018 |
December 2019 |
March 2020 |
November 18, 2016 |
February 6, 2019 |
|
- Washington University
Saint Louis, Missouri, United States - Naval Medical Research Unit Two
Phnom Penh, Cambodia - United States Army Medical Research Directorate Georgia
Tbilisi, Georgia - (and 7 more...)
|
|
| 76 |
NCT00403260 |
Completed |
Pyronaridine Artesunate (3:1) Versus Mefloquine Artesunate in P Falciparum Malaria Patients |
|
- Drug: Pyronaridine artesunate
- Drug: Mefloquine plus artesunate
|
Interventional
|
Phase 3 |
- Medicines for Malaria Venture
- Shin Poong Pharmaceuticals
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- PCR-corrected adequate clinical and parasitological response (ACPR) on Day 28
- Treatment success or failures will be classified according to WHO Guidelines 2005
- Incidence and severity of adverse events and of clinically significant laboratory results, ECG, vital signs or physical examination abnormalities
- (and 6 more...)
|
1269 |
All |
3 Years to 60 Years (Child, Adult) |
NCT00403260 |
SP-C-004-06 |
|
January 2007 |
October 2008 |
December 2008 |
November 23, 2006 |
January 22, 2009 |
|
- RAOTAP2/Centre Muraz
Bobo Dioulasso, Houet Province, Burkina Faso - Pailin Referral Hospital
Pailin, Pailin Province, Cambodia - Institut Pasteur
Abidjan, Côte D'Ivoire - (and 6 more...)
|
|
| 77 |
NCT00909051 |
Completed |
GlucoVIP - Diabetes Treatment by Glucobay® With a Special Therapeutic View to Chosen Patient Groups |
|
- Drug: Acarbose (Glucobay, BAYG5421)
|
Observational
|
|
|
Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Data collection on patients weight and waist circumference, fasting blood glucose, postprandial blood glucose (2h), HbA1C; exploratory analysis according to patient groups (concomitant cardiovascular disease groups, BMI)
|
15729 |
All |
18 Years and older (Adult, Older Adult) |
NCT00909051 |
14284
GB0701 |
|
March 2009 |
December 2010 |
December 2010 |
May 27, 2009 |
January 19, 2012 |
|
- Many Locations, Algeria
- Many Locations, Bosnia and Herzegovina
- Many Locations, Cambodia
- (and 13 more...)
|
|
| 78 |
NCT01600963 |
Withdrawn |
A Study to Evaluate the Efficacy and Safety of TMC207 in Patients With Pulmonary Infection With Multi-drug Resistant Mycobacterium Tuberculosis |
- Multi-drug Resistant Tuberculosis
|
- Drug: Arm A Double-blind Phase: TMC207
- Drug: Arm B Double-blind Phase: Placebo
- Drug: Treatment Failure During Double-blind Phase: TMC207
- Drug: Treatment Failure During Follow-up Phase: TMC207
|
Interventional
|
Phase 3 |
- Janssen Infectious Diseases BVBA
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Care Provider, Investigator)
- Primary Purpose: Treatment
|
- Number of patients with favorable treatment outcome at Week 60
- Number of patients with confirmed culture conversion at Week 84
- Number of patients with confirmed culture conversion at Week 60 or at time of trial discontinuation
- (and 24 more...)
|
0 |
All |
18 Years and older (Adult, Older Adult) |
NCT01600963 |
CR100807
TMC207-TIDP13-C210
2011-000653-23
U1111-1135-7013 |
|
March 2014 |
July 2016 |
November 2022 |
May 17, 2012 |
December 2, 2015 |
|
- Porto Alegre, Brazil
- Rio De Janeiro, Brazil
- Sao Paulo, Brazil
- (and 41 more...)
|
|
| 79 |
NCT01376167 |
Completed
Has Results |
Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax Relapse |
|
- Drug: Chloroquine 600mg
- Drug: Chloroquine 300mg
- Drug: Tafenoquine 50mg
- (and 8 more...)
|
Interventional
|
Phase 2 |
- GlaxoSmithKline
- Medicines for Malaria Venture
|
Industry / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Number of Participants With Recurrence-free Efficacy at 6 Months Post Dose
- Number of Participants With Recurrence-free Efficacy at 4 Months Post Dose
- Time to Recurrence of P Vivax Malaria
- (and 21 more...)
|
851 |
All |
16 Years and older (Child, Adult, Older Adult) |
NCT01376167 |
112582
TAF112582 |
|
April 24, 2014 |
November 18, 2016 |
November 18, 2016 |
June 20, 2011 |
April 23, 2018 |
April 23, 2018 |
- GSK Investigational Site
Bandarban, Bangladesh - GSK Investigational Site
Manaus, Amazonas, Brazil - GSK Investigational Site
Porto Velho, Rondônia, Brazil - (and 11 more...)
|
|
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