| 1 |
NCT03499197 |
Recruiting
New |
Heart TIMING - Heart Transplantation IMagING |
- Heart Transplant Failure and Rejection
- Magnetic Resonance Imaging
|
- Diagnostic Test: cardiac magnetic resonance imaging
|
Observational |
|
- Semmelweis University Heart and Vascular Center
- National Research, Development and Innovation Fund of Hungary, Project no. NVKP_16-1-2016-0017
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Coronary allograft vasculopathy
- Coronary allograft rejection
|
100 |
All |
18 Years and older (Adult, Senior) |
NCT03499197 |
Heart TIMING 001 |
|
January 15, 2018 |
January 15, 2021 |
January 15, 2026 |
April 17, 2018 |
April 17, 2018 |
|
- Heart and Vascular Center, Semmelweis University
Budapest, Hungary
|
| 2 |
NCT03488498 |
Recruiting
New |
Weight Bath Traction in Chronic Low Back Pain |
|
|
Observational |
|
- Polyclinic of the Hospitaller Brothers of St. John of God, Budapest
|
Other |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- prove the hypothesis that weight bath traction has favorable effect. of LBP using the change in the clinical parameters.
- Secondary objective was to evaluate whether it also leads to the improvement in the quality of life.
- Secondary objective was to evaluate whether it also leads to the improvement in the movements of the lumbal spine.
|
300 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT03488498 |
21396-3/2017/EKU |
|
May 10, 2017 |
December 31, 2019 |
December 31, 2020 |
April 5, 2018 |
April 10, 2018 |
|
- Polyclinic of the Hospitaller Brothers of St. John of God,
Budapest, Árpád Fejedelem Útja 7, Hungary
|
| 3 |
NCT03448705 |
Recruiting |
Safety of 4Fluart Intradermal Suspension for Injection (Influenza Vaccine, Whole-virion, Inactivated, Adjuvanted) in Adult Subjects |
|
- Biological: 4Fluart ID suspension for injection study drug 1 µg/0.1 ml, influenza vaccine (whole virion, inactivated, adjuvanted)
- Biological: 4Fluart ID suspension for injection study drug 2 µg/0.1 ml, influenza vaccine (whole virion, inactivated, adjuvanted)
- Biological: 3Fluart suspension for injection, influenza vaccine (whole virion, inactivated, adjuvanted)
|
Interventional |
Phase 1 |
- Fluart Innovative Vaccine Ltd, Hungary
- AMMY Ltd.
- PRENET-ING Ltd.
- (and 4 more...)
|
Industry / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Prevention
|
- Percentage of subjects reporting local and systemic adverse events following vaccination with either the study drugs and comparator drug
- Percentage of subjects having adverse events based on the physical examination as part of the clinical investigation following vaccination with either the study drugs and comparator drug
- Percentage of subjects having adverse events based on the vital signs as part of the clinical investigation following vaccination with either the study drugs and comparator drug
- (and 6 more...)
|
36 |
All |
18 Years to 59 Years (Adult) |
NCT03448705 |
4Fluart-H-21 |
|
January 31, 2018 |
April 11, 2018 |
April 11, 2018 |
February 28, 2018 |
February 28, 2018 |
|
- Drug Research Center
Balatonfüred, Veszprém, Hungary
|
| 4 |
NCT03438825 |
Recruiting |
PRediction of Early PostoperAtive Right vEntricular Failure in Mitral Valve Replacement/Repair Patients |
- Right Heart Failure
- Right Ventricular Dysfunction
- Right Ventricular Failure
- Mitral Valve Disease
|
- Procedure: Mitral valve replacement/repair
|
Observational |
|
- Semmelweis University Heart and Vascular Center
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- right ventricular failure
|
100 |
All |
18 Years and older (Adult, Senior) |
NCT03438825 |
PREPARE-MVR1.0 |
PREPARE-MVR |
October 2016 |
October 2019 |
October 2019 |
February 20, 2018 |
February 20, 2018 |
|
- Semmelweis University Heart and Vascular Center
Budapest, Hungary
|
| 5 |
NCT03436459 |
Completed |
Effects of Extracorporeal Shock Wave Therapy and Low Level Laser Therapy in Myofascial Pain Syndrome |
|
- Device: Extracorporeal Shock Wave Therapy
- Device: Low Level Laser Therapy
|
Interventional |
Not Applicable |
- Petz Aladar County Teaching Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- change in severity of pain at rest
- change in severity of pressure pain
- change in function (percentage of disability)
- change in quality of life
|
60 |
All |
18 Years and older (Adult, Senior) |
NCT03436459 |
PetzAladarCTH |
|
February 2016 |
February 2017 |
September 2017 |
February 16, 2018 |
February 20, 2018 |
|
- Petz Aladár County Teaching Hospital
Győr, Hungary
|
| 6 |
NCT03427762 |
Active, not recruiting |
Compare the Effects of Agility and Cycling Exercise Training on Mobility and Balance in PD and Healthy Old Adults |
- Healthy
- Movement Disorders
- Parkinson Disease
- Condition
|
|
Interventional |
Not Applicable |
- Somogy Megyei Kaposi Mór Teaching Hospital
- University of Groningen
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Postural instability
- quality of life
- balance test
- (and 2 more...)
|
3 |
All |
55 Years to 80 Years (Adult, Senior) |
NCT03427762 |
IKEB009/2017 |
|
February 3, 2018 |
April 15, 2018 |
May 10, 2018 |
February 9, 2018 |
February 12, 2018 |
|
- József Tollár
Kaposvár, Somogy, Hungary
|
| 7 |
NCT03424538 |
Enrolling by invitation |
The Effect of Neurorehabilitation Therapy on Postural Control, Mobility and Quality of Life in Multiple Sclerosis Patients |
- Multiple Sclerosis, Chronic Progressive
- Multiple Sclerosis, Primary Progressive
|
- Other: Neurorehabilitation
- Other: Physiotherapy
|
Interventional |
Not Applicable |
- Somogy Megyei Kaposi Mór Teaching Hospital
- University Medical Center Groningen
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- Postural instability
- quality of life
- balance test
- (and 2 more...)
|
2 |
All |
35 Years to 60 Years (Adult) |
NCT03424538 |
IKEB008/2017 |
|
February 5, 2018 |
April 16, 2018 |
June 10, 2018 |
February 7, 2018 |
April 17, 2018 |
|
- Somogy Megyei Kaposi Mór Teaching Hospital
Kaposvár, Somogy, Hungary
|
| 8 |
NCT03410576 |
Completed |
Perioperative Time Course of MMP-9 and Its Inhibitor During Carotid Artery Stenting and Carotid Endarterectomy |
- Carotid Stenosis
- Ischemia Reperfusion Injury
|
- Procedure: Carotid artery stenting
- Procedure: Carotid endarterectomy
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Plasma MMP-9 concentrations
- Plasma TIMP-1 concentrations
- MMP-9/TIMP-1 ratio
|
25 |
All |
18 Years and older (Adult, Senior) |
NCT03410576 |
5016 |
|
October 1, 2013 |
November 30, 2015 |
November 30, 2015 |
January 25, 2018 |
January 25, 2018 |
|
- Department of Anaesthesiology and Intensive Therapy, Medical School, University of Pécs
Pécs, Baranya, Hungary
|
| 9 |
NCT03390036 |
Enrolling by invitation |
Study of Cingal™ for the Relief of Knee Osteoarthritis Compared to Triamcinolone Hexacetonide at 39 Weeks Follow up |
|
- Drug: Cingal
- Device: Monovisc
- Drug: Triamcinolone Hexacetonide
|
Interventional |
Phase 3 |
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Treatment
|
- OMERACT-OARSI Responder Rate
|
576 |
All |
40 Years to 75 Years (Adult, Senior) |
NCT03390036 |
Cingal 17-02 |
Cingal17-02 |
December 7, 2017 |
July 2018 |
July 2018 |
January 4, 2018 |
January 4, 2018 |
|
- Health Center of Downtown-Lipotvaros, Orthopedic Outpatient Clinic (Belvárosi-Lipótvárosi Egészségügyi Szolgálat Ortopeadia)
Budapest, Hungary
|
| 10 |
NCT03385642 |
Completed |
Follow-Up Study Evaluating the Long Term Outcome of ChondroMimetic in the Treatment of Osteochondral Defects in the Knee |
|
|
Observational |
|
|
Industry |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Change from 0MCM0107 baseline in Modified Cincinnati Rating System
- KOOS (Knee injury and Osteoarthritis Outcome Score
- Cartilage repair tissue quantity and quality using 3D quantitative MRI analysis
- (and 2 more...)
|
15 |
All |
Child, Adult, Senior |
NCT03385642 |
0MCM0107-2 |
|
May 29, 2017 |
February 22, 2018 |
February 22, 2018 |
December 28, 2017 |
April 17, 2018 |
|
- Uzsoki Hospital
Budapest, Hungary
|
| 11 |
NCT03377075 |
Active, not recruiting |
Study of the Choroidal and Retinal Thickness in Relation to Axial Length. |
|
- Device: AL measurement
- Device: OCT
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Relation of choroidal thickness to axial length
- Relation of retinal thickness to axial length
- Influence of age on results
- Influence of gender on results
|
65 |
All |
18 Years to 29 Years (Adult) |
NCT03377075 |
CHORAL-1249 |
CHORAL |
February 6, 2017 |
August 31, 2017 |
March 31, 2018 |
December 19, 2017 |
December 20, 2017 |
|
- Semmelweis University, Department of Ophthalmology
Budapest, Hungary
|
| 12 |
NCT03364465 |
Active, not recruiting |
Lung Protective One-lung Ventilation With Fix and Variable Tidal Volume |
- Hypoxemia
- Pulmonary Sepsis
- ARDS, Human
- Pneumonia
|
- Other: change of ventilatory settings
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Prevention
|
- intraoperative oxygenation
- postoperative pulmonary complications
- postoperative extra-pulmonary complications
- (and 2 more...)
|
140 |
All |
18 Years and older (Adult, Senior) |
NCT03364465 |
DE RKEB/IKEB 4737-2017 |
|
February 1, 2017 |
April 1, 2018 |
April 1, 2018 |
December 6, 2017 |
December 7, 2017 |
|
- University of Debrecen, Department of Anesthesiology and Intensive Care
Debrecen, Hungary
|
| 13 |
NCT03357146 |
Active, not recruiting |
Optical Coherence Tomography Angiography Examinations in Chronic Retinal Artery Occlusion |
|
- Device: Optical coherence tomography angiography
|
Observational |
|
|
Other |
- Observational Model: Cohort
- Time Perspective: Cross-Sectional
|
- Capillary density in relation to healthy subjects
- Correlation of capillary density and retinal thickness
|
50 |
All |
18 Years to 99 Years (Adult, Senior) |
NCT03357146 |
RAO-OCTA-1253 |
RAO-OCTA |
January 9, 2017 |
May 31, 2018 |
July 31, 2018 |
November 29, 2017 |
February 5, 2018 |
|
- Semmelweis University, Department of Ophthalmology
Budapest, Hungary
|
| 14 |
NCT03288051 |
Completed |
Effects of Intraoperative, Goal-directed Crystalloid vs. Colloid Fluid Resuscitation on Free Flaps |
|
- Other: Fluid management
- Drug: Norepinephrine
- Drug: Dobutamine
|
Interventional |
Not Applicable |
- Szeged University
- Department of Oral and Maxillofacial Surgery, University of Szeged
- Institute of Surgical Research, University of Szeged
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Changes of Pulse pressure variation during the operation and the post-operative 24 hours
- Assesment of free falp microcirculation by laser dopler flowmetry method.
- Total need of Norepinephrine and Dobutamine during surgery and the post-operative 24 hours.
- (and 5 more...)
|
30 |
All |
18 Years and older (Adult, Senior) |
NCT03288051 |
Free Flap Microcirculation |
|
February 1, 2014 |
February 20, 2017 |
February 20, 2017 |
September 19, 2017 |
September 19, 2017 |
|
- Department of Anaesthesiology and Intensive Therapy
Szeged, Csongrád, Hungary
|
| 15 |
NCT03271008 |
Recruiting |
Comparison of the Vividtrac™ and Other Videolaryngoscopes in Clinical Practice |
|
- Device: Direct laryngoscopy
- Device: Vividtrac videolaryngoscope
- Device: KingVision videolaryngoscope
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Outcomes Assessor)
- Primary Purpose: Supportive Care
|
- Intubation time
- Laryngoscopy time
- Percentage of glottic opening (POGO) score
- (and 2 more...)
|
150 |
All |
18 Years and older (Adult, Senior) |
NCT03271008 |
6328 |
|
January 1, 2017 |
July 1, 2018 |
July 1, 2018 |
September 1, 2017 |
September 1, 2017 |
|
- University of Pécs, Dept. of Anaesthesia and Intensive Care
Pécs, Baranya county, Hungary
|
| 16 |
NCT03242694 |
Recruiting |
Left Atrial Function Analysis for Patients With Persistent Atrial Fibrillation Undergoing Pulmonary Vein Isolation |
- Persistent Atrial Fibrillation
- Catheter Ablation
|
- Diagnostic Test: LA pressure, voltage map, strain, scar-map, blood sampling
- Procedure: pulmonary vein isolation
|
Observational |
|
- Semmelweis University Heart and Vascular Center
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- one-year success of pulmonary vein isolation
- acute unsuccessful pulmonary vein isolation
- usage of antiarrhythmic drugs after the three-month blanking period
- (and 4 more...)
|
100 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT03242694 |
LAMPP 1.0 |
LAMPP |
August 1, 2017 |
December 31, 2019 |
December 31, 2019 |
August 8, 2017 |
August 8, 2017 |
|
- Heart and Vascular Center of Semmelweis University
Budapest, Hungary
|
| 17 |
NCT03234725 |
Recruiting |
Analysis of New Endoscopic Features and Variable Stiffness in Colonoscopy: Prospective Randomised Trial |
- Colorectal Adenoma
- Colorectal Adenomatous Polyp
|
|
Observational |
|
- Bács-Kiskun County Teaching Hospital
- Endo-Kapszula Privat Medical Center
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- diagnostic value of the computer algorithm
- Number of detected serrated polyps
- Number of detected polyps
- (and 10 more...)
|
1000 |
All |
18 Years to 99 Years (Adult, Senior) |
NCT03234725 |
Deep001 |
ELUFIBLI |
October 1, 2016 |
September 30, 2018 |
September 30, 2022 |
July 31, 2017 |
August 4, 2017 |
|
- Bács Kiskun County and Teaching Hospital
Kecskemét, Nyiri street 38, Hungary
|
| 18 |
NCT03233958 |
Recruiting |
The Psychosocial Effects of Systemic / Family Constellation |
- Mild to Moderate Psychopathological Symptoms
|
- Behavioral: Systemic / family constellation
|
Observational |
|
- Károli Gáspár University of the Reformed Church in Hungary
- University of Toronto
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- Change in scores on the Brief Symptom Inventory
- Change in answers to ad hoc items developed for qualitative analysis
- Change in scores on the Experience in Personal Social Systems Questionnaire
- (and 5 more...)
|
200 |
All |
18 Years and older (Adult, Senior) |
NCT03233958 |
325/2017/P |
|
July 1, 2017 |
July 1, 2018 |
December 1, 2018 |
July 31, 2017 |
July 31, 2017 |
|
- Károli Gáspár University of the Reformed Church in Hungary
Budapest, Hungary
|
| 19 |
NCT03193268 |
Enrolling by invitation |
Effects of Intensity-matched Agility and Cycling Exercise Training on PD Patients' Clinical Symptoms, Posture, and Mobility |
- Parkinson Disease
- Balance
- Rehabilitation
- Motor Function
|
- Other: Single-blind RTC of PD patients
- Other: cycling
|
Interventional |
Not Applicable |
- Somogy Megyei Kaposi Mór Teaching Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
- Quality of life
- Borg test
- PDQ-39
- SPPB test (gait, balance, leg stregth)
|
2 |
All |
55 Years to 85 Years (Adult, Senior) |
NCT03193268 |
IKEB0014/2015 |
|
October 15, 2017 |
November 21, 2017 |
November 21, 2017 |
June 20, 2017 |
October 4, 2017 |
|
- Somogy Megyei Kaposi Mór Teaching Hospital
Kaposvár, Somogy, Hungary
|
| 20 |
NCT03189680 |
Enrolling by invitation |
Agility Training in Parkinson's Disease |
|
|
Interventional |
Not Applicable |
- Somogy Megyei Kaposi Mór Teaching Hospital
- University Medical Center Groningen
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Investigator)
- Primary Purpose: Treatment
|
|
3 |
All |
55 Years to 85 Years (Adult, Senior) |
NCT03189680 |
IKEB0012/2015 |
|
May 11, 2015 |
May 31, 2017 |
June 30, 2017 |
June 16, 2017 |
June 20, 2017 |
|
- Somogy Megyei Kaposi Mór Teaching Hospital
Kaposvár, Somogy, Hungary
|
| 21 |
NCT03145441 |
Recruiting |
Intraoperative Use of Extracorporeal Cytokine Adsorption During Orthotopic Heart Transplantation |
- Cardiac Transplantation
- Cardiopulmonary Bypass
|
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- The incidence of early rejection
- Cytokine and complement levels
- Inflammatory reaction
- (and 5 more...)
|
60 |
All |
18 Years and older (Adult, Senior) |
NCT03145441 |
SU-AITK/VM-2017/1 |
|
April 9, 2018 |
March 31, 2019 |
December 31, 2019 |
May 9, 2017 |
April 17, 2018 |
|
- Semmelweis University
Budapest, Hungary
|
| 22 |
NCT03136614 |
Recruiting |
Prognostic Value of the Arteriograph in the Surgical Theatre and at the Intensive Care Unit |
|
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Screening
|
- Number and degree of hypotensive episodes predicted by preoperative values of pulse wave velocity.
- Correlation between systemic vascular resistance and aortic augmentation index
- Identity of cardiac output given by the PiCCO monitor and cardiac output given by the Arteriograph
|
30 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT03136614 |
Arteriograph-2016 |
|
June 2016 |
December 2017 |
December 2017 |
May 2, 2017 |
August 30, 2017 |
|
- Department of Anaesthesiology and Intensive Therapy
Szeged, Csongrád, Hungary
|
| 23 |
NCT03070548 |
Completed |
A Study of Talazoparib in Patients With Advanced Solid Tumors |
|
|
Interventional |
Phase 1 |
|
Industry |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Excretion of 14C radioactivity in urine and feces measured as time course of excretion
- The recovery of 14C radioactivity measured as a percentage of the administered dose.
- Cmax of talazoparib
- (and 7 more...)
|
6 |
All |
18 Years and older (Adult, Senior) |
NCT03070548 |
MDV3800-03
C3441003
2016-001394-33 |
|
September 27, 2016 |
June 1, 2017 |
June 30, 2017 |
March 3, 2017 |
April 23, 2018 |
|
- PRA Magyarorszag Kft, Fazis I-es Klinikai Farmakologiai Vizsgalohely
Budapest, Hungary
|
| 24 |
NCT03044418 |
Active, not recruiting |
Anesthesia With Endotracheal Laser Tube |
- Anesthesia
- Anesthesia Morbidity
|
- Other: application of ET laser tube in propofol anesthesia
|
Interventional |
Not Applicable |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- Side effects of anesthesia during endotracheal laser surgery
|
30 |
All |
Child, Adult, Senior |
NCT03044418 |
6419 |
|
January 1, 2017 |
March 31, 2017 |
April 30, 2017 |
February 7, 2017 |
February 7, 2017 |
|
- PTE Department of ENT
Pecs, Hungary
|
| 25 |
NCT03032211 |
Withdrawn |
Optimal Balance Alfapump® System Feasibility Study |
|
|
Interventional |
Phase 1 |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Occurrence of adverse events (AEs) and serious adverse events (SAEs)
|
0 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT03032211 |
2016-CHF-003 |
OPTIMALBALANCE |
December 31, 2017 |
December 31, 2020 |
December 31, 2020 |
January 26, 2017 |
January 26, 2017 |
|
- Military Hospital - State Health Centre
Budapest, Hungary
|
| 26 |
NCT03025737 |
Recruiting |
Semmelweis Sport Study |
|
|
Observational |
|
- Semmelweis University Heart and Vascular Center
- National Research, Development and Innovation Office (NKFIH) of Hungary (K 120277).
|
Other |
- Observational Model: Case-Control
- Time Perspective: Prospective
|
- The primary analysis will be an investigation regarding the athletic adaptation using CMR
- The primary analysis will be an investigation regarding the athletic adaptation using cardiopulmonary exercise testing
- The primary analysis will be an investigation regarding the athletic adaptation using resting ECG
- The primary analysis will be an investigation regarding the athletic adaptation using 24-Hour Holter ECG
|
150 |
All |
12 Years and older (Child, Adult, Senior) |
NCT03025737 |
Semmelweis Sport |
|
January 2017 |
January 2018 |
January 2020 |
January 19, 2017 |
January 19, 2017 |
|
- Heart and Vascular Center, Semmelweis University
Budapest, Hungary
|
| 27 |
NCT02986100 |
Active, not recruiting |
Absorption, Metabolism, and Excretion Following a Single Oral Dose of [14C]-Rucaparib |
|
- Drug: C-14 labeled Rucaparib
- Drug: Rucaparib
|
Interventional |
Phase 1 |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Other
|
- Pharmacokinetics of 14C-labeled rucaparib (radioactivity in whole blood and plasma): tmax
- Pharmacokinetics of 14C-labeled rucaparib(Radioactivity in whole blood and plasma): Cmax
- Pharmacokinetics of 14C-labeled rucaparib(Radioactivity in whole blood and plasma): t1/2
- (and 12 more...)
|
6 |
All |
18 Years and older (Adult, Senior) |
NCT02986100 |
CO-338-045
2015-004394-32 |
AME |
November 2016 |
December 2017 |
June 2018 |
December 8, 2016 |
February 2, 2018 |
|
- PRA Magyarország Kft.
Budapest, Rottenbiller Utca 13, Hungary
|
| 28 |
NCT02981186 |
Completed |
Comparison of Visual Outcomes After Implantation of the POD AY GF F (PhysIOL) and the POD AY 26P F (PhysIOL) |
|
- Device: IOL implantation experimental
- Device: IOL implantation comparator
|
Interventional |
Not Applicable |
|
Industry |
- Allocation: Randomized
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Visual Acuity at far, near and intermediate distance
|
25 |
All |
50 Years and older (Adult, Senior) |
NCT02981186 |
PHY1603 |
|
November 2, 2016 |
September 25, 2017 |
September 25, 2017 |
December 5, 2016 |
December 21, 2017 |
|
- Semmelweis University - Department of Ophthalmology
Budapest, Hungary
|
| 29 |
NCT02975024 |
Completed |
Blood Flow Analysis of the Human Mucosa After Vestibuloplasty Procedures |
|
- Device: laser speckle contrast imaging of the oral mucosa
- Device: wound fluid measurement
- Device: quantitative determination of VEGF
|
Observational |
|
- Semmelweis University
- Hungarian Scientific Research Fund
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- Postoperative blood flow changes of the oral mucosa
- Wound fluid volume measurement
- Evaluation of the periodontal parameters at teeth at the surgical site: a composite outcome measure consisting of multiple measures.
- Quantitative determination of Vascular Endothelial Growth Factor (VEGF) of the wound fluid
|
8 |
All |
18 Years to 45 Years (Adult) |
NCT02975024 |
3/2013 |
|
November 2016 |
December 2017 |
December 2017 |
November 29, 2016 |
April 18, 2018 |
|
- Janos Vag
Budapest, Hungary
|
| 30 |
NCT02947568 |
Recruiting |
Genetical Background of Non-alcoholic Fatty Liver Disease (NAFLD) in Diabetes Mellitus and in Chronic Kidney Disease |
- Non-alcoholic Fatty Liver Disease
- Chronic Kidney Disease
- Diabetes Mellitus
|
- Other: non-interventional study
|
Observational |
|
- University of Pecs
- Teaching Hospital Markusovszky, Szombathely
- Fresenius Medical Care North America
|
Other / Industry |
- Observational Model: Case-Only
- Time Perspective: Cross-Sectional
|
- Association of NFS (NAFLD fibrosis score) and HSI (hepatic steatosis index) with underlying conditions
- Association of genetical factors with NFS and HSI
- Association of hepatic steatosis with renal function
- (and 7 more...)
|
600 |
All |
18 Years to 90 Years (Adult, Senior) |
NCT02947568 |
Pecs_NAFLD_01 |
NAFLDDMCKD |
March 2016 |
December 2018 |
December 2019 |
October 28, 2016 |
January 9, 2018 |
|
- 2nd Department of Medicine and Nephrological Center
Pécs, Baranya, Hungary
|
| 31 |
NCT02947555 |
Recruiting |
Cardiovascular Risk Assesment in Diabetic Patients Via Lens Autofluorecscence Detection |
- Diabetic Patients With/Without Atherosclerotic Diseases
|
- Other: Non interventional
|
Observational |
|
- Dr. Gergő Molnár
- Bajcsy-Zsilinszky Kórház
- Petz Aladar County Teaching Hospital
- (and 4 more...)
|
Other |
- Observational Model: Case-Control
- Time Perspective: Cross-Sectional
|
- Association of lens autofluorescence with atherosclerotic vascular events
- Association of lens autofluorescence with the perscene of diabetes
- Association of lens autofluorescence with renal function
- (and 4 more...)
|
420 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT02947555 |
PTEBEL 01/2015 |
CRADILA |
April 2016 |
April 2018 |
December 2018 |
October 28, 2016 |
August 29, 2017 |
|
- 2nd Department of Medicine and Nephrological Center
Pécs, Baranya, Hungary
|
| 32 |
NCT02935803 |
Recruiting |
A Study on the Anti-incontinent Effectiveness of the mTVM Method in POPQ Stage II-III Patients |
- Uterine Prolapse
- Urinary Stress Incontinence
- Side Effects
|
- Procedure: Trans-vaginal Mesh operation
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Double (Participant, Investigator)
- Primary Purpose: Treatment
|
- Efficacy of the mTVM on genuine stress incontinence.
- Telorability of the mTVM method
- Improvement in sexual life
- (and 2 more...)
|
76 |
Female |
45 Years to 75 Years (Adult, Senior) |
NCT02935803 |
TVM/mTVM 55/2016 |
TVMvsmTVM |
July 2016 |
June 2017 |
June 2020 |
October 18, 2016 |
October 18, 2016 |
|
- Univ. of Szeged. Dep. of Obstetrics and Gynaecology
Szeged, Hungary
|
| 33 |
NCT02920749 |
Completed
Has Results |
Study of Anaesthesia Costs and Recovery Profiles |
|
- Drug: Sevoflurane group A
- Drug: Sevoflurane group B
- Drug: Propofol group C
- Drug: Propofol group D
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Treatment
|
- Drug Consumption
- Costs of Anaesthesia
|
120 |
All |
18 Years to 65 Years (Adult) |
NCT02920749 |
316-2336/KK15 |
SACRP |
September 2014 |
October 2016 |
October 2016 |
September 30, 2016 |
February 6, 2018 |
December 6, 2016 |
- Tímea Bocskai
Pecs, Ifjusag Street 13., Hungary
|
| 34 |
NCT02893657 |
Recruiting |
The Role and Dynamics of Liver Dysfunction in Patients Undergoing Cardiac Surgery |
- Cardiac Surgery
- Hepatic Impairment
- Heart Failure
|
|
Observational |
|
- Semmelweis University Heart and Vascular Center
- Semmelweis University
|
Other |
- Observational Model: Cohort
- Time Perspective: Prospective
|
- The composite of in-hospital death of any cause
- Length of hospital stay
- Length of ICU stay
- (and 6 more...)
|
150 |
All |
18 Years and older (Adult, Senior) |
NCT02893657 |
SE AITK VSZÉK LIVER |
|
December 1, 2017 |
September 2018 |
September 2019 |
September 8, 2016 |
April 25, 2018 |
|
- Heart and Vascular Center, Semmelweis University
Budapest, Hungary
|
| 35 |
NCT02835456 |
Completed |
Does Micropattern on Urinary Catheter Surface Reduce Urinary Tract Infections? |
- Catheter Associated Urinary Tract Infections
|
- Device: Sharklet Catheter insertion
- Device: Silicone Foley Catheter insertion
|
Interventional |
Phase 1 |
- Jahn Ferenc South Pest Teaching Hospital
- Cook Group Incorporated
|
Other / Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Prevention
|
- Catheter scrapings examined for colonization/biofilm burden and compared to the urine screen collected from the participant (cfu/mL)
- Number of symptomatic Urinary tract infections (UTIs) determined by urine culture.
- Incidence of bacteremia
- (and 5 more...)
|
50 |
All |
18 Years and older (Adult, Senior) |
NCT02835456 |
RCSFC028514 |
SHARKLET |
August 2016 |
November 2016 |
December 2016 |
July 18, 2016 |
January 4, 2017 |
|
- Jahn Ferenc South Pest Teaching Hospital
Budapest, Hungary
|
| 36 |
NCT02828930 |
Completed |
A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies) |
|
- Drug: Idasanutlin
- Drug: Placebo
- Drug: [13C]-radiolabeled Idasanutlin
- Drug: [14C]-radiolabeled Idasanutlin
|
Interventional |
Phase 1 |
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Time to Reach Maximum Observed Plasma Concentration (Tmax) of Unlabeled Idasanutlin
- Maximum Observed Plasma Concentration (Cmax) of Unlabeled Idasanutlin
- Area Under the Plasma Concentration Time-Curve From Time Zero to Extrapolated Infinite Time (AUC [0-inf]) of Unlabeled Idasanutlin
- (and 38 more...)
|
8 |
All |
18 Years and older (Adult, Senior) |
NCT02828930 |
NP29910
RG7388
2015-002532-40 |
|
September 8, 2016 |
June 19, 2017 |
June 19, 2017 |
July 12, 2016 |
December 18, 2017 |
|
- Magyar Honvedseg Egeszsegugyi Kozpont
Budapest, Hungary
|
| 37 |
NCT02828722 |
Not yet recruiting |
Proof of Concept Trial to Confirm That the Recovery of Patients Treated in the Intensive Care Unit Requiring Mechanical Ventilation is Beneficially Affected by the Environmental Simulation of Daytime and Night Time Alternation as Well as by the Nutrition Protocol Corresponding to the Daily Rhythm |
- Critical Illness
- Mechanical Ventilation
|
- Other: Controlled light and noise
- Other: Controlled nutrition
|
Interventional |
Not Applicable |
- Achros Health Technologies Corporation
|
Industry |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Change of the Multiple Organ Dysfunction Score value (delta MODS) from baseline to the end of the study treatment
- Change of the MODS value (delta MODS) between worst and last score during the study treatment
- Number of participants with gastric retention
- Number of participants with delirium
|
45 |
All |
18 Years and older (Adult, Senior) |
NCT02828722 |
ACHROS CRC-003 |
|
November 2016 |
April 2017 |
June 2017 |
July 12, 2016 |
July 12, 2016 |
|
- University of Szeged Faculty of Medicine, Department of Anaesthesiology and Intensive Therapy
Szeged, Hungary
|
| 38 |
NCT02826200 |
Recruiting |
Rule Out Transcatheter Aortic Valve Thrombosis With Post Implantation Computed Tomography (RETORIC) |
- Prosthetic Cardiac Valve Thrombosis
- Cerebrovascular Accident
- Prosthetic Valve Malfunction
|
- Drug: Acenocoumarol
- Other: Standard of care
|
Interventional |
Phase 4 |
- Semmelweis University Heart and Vascular Center
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Outcomes Assessor)
- Primary Purpose: Prevention
|
- Reduced leaflet motion and/or valve thrombosis
- Presence of ischemic brain lesions
|
200 |
All |
18 Years to 100 Years (Adult, Senior) |
NCT02826200 |
The RETORIC study |
RETORIC |
July 2016 |
July 2018 |
January 2019 |
July 7, 2016 |
January 18, 2017 |
|
- Heart and Vascular Center, Semmelweis University
Budapest, Hungary
|
| 39 |
NCT02804555 |
Completed |
Effects of Intraoperative Oxygen Therapy on Oxygenation of Newborns Born Via Elective Cesarian Section |
- Obstetrical Complication of Anesthesia
|
|
Interventional |
Not Applicable |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Single (Participant)
- Primary Purpose: Supportive Care
|
- Hyperoxia Newborns
- Maternal hyperoxia
- Alterations in newborns' enzyme functions due to maternal hyperoxia
|
107 |
All |
Child, Adult, Senior |
NCT02804555 |
Maternal hyperoxia |
|
June 2013 |
June 2016 |
November 30, 2016 |
June 17, 2016 |
April 27, 2017 |
|
- Department of Anaesthesiology and Intensive Therapy
Szeged, Csongrád, Hungary
|
| 40 |
NCT02759094 |
Recruiting |
Evaluation of Safety and Effectiveness of the RefluxStop Device in the Management of GERD |
|
- Device: Treatment with RefluxStop
|
Interventional |
Not Applicable |
- Implantica CE & Production Ltd
|
Industry |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Assessment of incidence of serious adverse device effects (SADEs) and procedure-related serious adverse events (SAEs)
- Assessment of percent reduction from baseline of GERD symptoms based on the GERD-HRQL score (questions 1-10) measured after the procedure
- Assessment of incidence of adverse device effects (ADEs) and procedure-related adverse events (AEs)
- (and 7 more...)
|
50 |
All |
18 Years to 75 Years (Adult, Senior) |
NCT02759094 |
RXI 001 |
|
December 2016 |
July 2017 |
February 2018 |
May 3, 2016 |
June 12, 2017 |
|
- Semmelweis University
Budapest, Hungary
|
| 41 |
NCT02706028 |
Completed |
Effects of Underwater Ultrasound Therapy on Hand Function and Quality of Life in Patients With Rheumatoid Arthritis |
|
- Device: underwater ultrasound
- Device: sham underwater ultrasound
|
Interventional |
Not Applicable |
- Petz Aladar County Teaching Hospital
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Triple (Participant, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- change in erythrocyte sedimentation rate
- change in C-reactive protein
- change in disease activity
- (and 8 more...)
|
50 |
All |
18 Years and older (Adult, Senior) |
NCT02706028 |
PetzACTH |
|
February 2013 |
September 2014 |
November 2014 |
March 11, 2016 |
March 11, 2016 |
|
- Petz Aladár County Teaching Hospital
Győr, Válassza ki a megyét, Hungary
|
| 42 |
NCT02700854 |
Recruiting |
Hypoxic-Ischemic Encephalopathy Therapy Optimization in Neonates for Better Neuroprotection With Inhalative CO2 |
- Hypoxic-Ischaemic Encephalopathy
- Perinatal Asphyxia
- Hypocapnia
|
- Other: 5% carbon-dioxide inhalation
|
Interventional |
Phase 1 |
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Percentage of time spent in the desired pCO2 range of 40-60 mmHg (temp. corrected) during CO2 inhalation.
- Number of seizures, either detected clinically or by amplitude integrated EEG monitoring
- Time until the end point of metabolic acidosis (BE > -5 mmol/L)
- (and 6 more...)
|
10 |
All |
up to 6 Hours (Child) |
NCT02700854 |
1Ped-AsphHENRIC001 |
HENRIC |
February 2016 |
September 2017 |
February 2020 |
March 7, 2016 |
March 17, 2017 |
|
- Semmelweis University, 1st Department of Pediatrics
Budapest, Hungary
|
| 43 |
NCT02700828 |
Active, not recruiting |
Hydrocortisone Treatment In Systemic Low Blood Pressure During Hypothermia in Asphyxiated Newborns |
- Hypoxic-Ischemic Encephalopathy
- Asphyxia
|
- Drug: Hydrocortisone
- Drug: Placebo
|
Interventional |
Phase 2
Phase 3 |
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Treatment
|
- Compare mean arterial blood pressure (MAP) change in the patients receiving hydrocortisone vs placebo
- Frequency of initially low serum cortisol in hypotensive asphyxiated newborns undergoing therapeutic hypothermia
- Length of dopamine treatment in the patients receiving hydrocortisone vs placebo
- (and 4 more...)
|
32 |
All |
up to 72 Hours (Child) |
NCT02700828 |
1Ped-AsphCort 001 |
CORTISoL |
February 2016 |
November 2017 |
February 2020 |
March 7, 2016 |
April 18, 2018 |
|
- Semmelweis University, 1st Department of Paediatrics
Budapest, Pest, Hungary
|
| 44 |
NCT02691130 |
Completed |
Assess the Safety and Immunogenicity of M-001 as A Standalone Influenza Vaccine and as A H5N1 Vaccine Primer in Adults |
|
- Biological: Multimeric 001 (M-001)
- Biological: H5N1 influenza vaccine
- Biological: Saline
|
Interventional |
Phase 2 |
- BiondVax Pharmaceuticals ltd.
- Seventh Framework Programme
|
Industry / Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
- Primary Purpose: Prevention
|
- For each vaccine group the incidence rate of subjects with solicited AE(s) with 95% confidence interval
- For each vaccine group the percentage of subjects with SAE(s) with 95% confidence interval
- For each vaccine group the influenza-specific cellular immune responses evaluated by multi-parametric FACS analysis
- For each vaccine group the antibody responses to the H5 vaccine strain evaluated by hemaglutination inhibition (HI) assay
|
224 |
All |
18 Years to 60 Years (Adult) |
NCT02691130 |
BVX-007 |
|
November 2015 |
October 2016 |
January 2017 |
February 25, 2016 |
February 9, 2018 |
|
- St Istvan St laszlo Hospital
Budapest, Hungary
|
| 45 |
NCT02686866 |
Unknown † |
Body Composition Measurements in Chronic Heart Failure |
- Cachexia
- Sarcopenia
- Body Composition
|
- Device: bioelectrical impedance analysis (Bodystat, Quadscan 4000)
- Device: dual-energy X-ray absorptiometry (Hologic, Delphi QDR)
- Device: hand grip strength
|
Interventional |
Phase 4 |
- Hungarian Institute of Cardiology
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Compare total body water (TBW) measured with BIA and DXA.
- Compare fat mass (FM) measured with BIA and DXA.
- Compare fat-free mass (FFM) measured with BIA and DXA.
- (and 3 more...)
|
35 |
All |
18 Years and older (Adult, Senior) |
NCT02686866 |
101568/2015/OTIG |
|
January 2016 |
June 2016 |
June 2016 |
February 22, 2016 |
February 22, 2016 |
|
- Hungarian Institute of Cardiology
Budapest, Hungary
|
| 46 |
NCT02662439 |
Suspended |
Bioimpedance Analysis in Chronic Heart Failure |
|
- Device: Body Composition Monitor (BCM)
|
Interventional |
Not Applicable |
- Peter Studinger
- Semmelweis University
|
Other |
- Allocation: Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Diagnostic
|
- Re-hospitalization rate
- All cause mortality
|
240 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02662439 |
HF-BCM-15-1 |
|
February 2016 |
December 2018 |
|
January 25, 2016 |
June 1, 2017 |
|
- First Department of Medicine, Semmelweis University
Budapest, Hungary
|
| 47 |
NCT02660697 |
Completed |
3D Radiographic Evaluation of a Novel Implant Site Development Technique |
- Tooth Extraction Status Nos
- Edentulous Alveolar Ridge
|
- Procedure: Extraction site development
|
Interventional |
Phase 4 |
|
Other |
- Allocation: Non-Randomized
- Intervention Model: Parallel Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- Orovestibular socket dimension
- Minimal orovestibular socket dimension feasible for implant placement
- Vertical socket dimension
- Socket area
|
43 |
All |
18 Years to 80 Years (Adult, Senior) |
NCT02660697 |
XSD-Semmelweis-Perio |
|
December 2007 |
December 2014 |
December 2014 |
January 21, 2016 |
January 26, 2016 |
|
- Semmelweis University Department of Periodontology
Budapest, Hungary
|
| 48 |
NCT02659878 |
Recruiting |
Takotsubo Cardiomyopathy in Patients Suffering From Acute Non-traumatic Subarachnoid Hemorrhage |
- Takotsubo Cardiomyopathy
- Subarachnoid Hemorrhage
|
- Procedure: bleeding, intraventricular and/ or intracerebral hemorrhage.
|
Observational |
|
|
Other |
- Observational Model: Case-Only
- Time Perspective: Prospective
|
- ECG abnormalities:Corrected QT Interval (QTc), T wave, ST segment, arrhythmia
- urine metanephrine, normetanephrine levels
- Enzyme level associated with myocardial tissue necrosis
- (and 2 more...)
|
150 |
All |
18 Years and older (Adult, Senior) |
NCT02659878 |
HBR/052/00436-2/2015
DE RKEB/IKEB:4317-2015 |
|
February 2015 |
February 2018 |
August 2018 |
January 21, 2016 |
March 9, 2017 |
|
- UNIVERSITY OF DEBRECEN FACULTY OF MEDICINE Department of Anesthesiology and Intensive Care
Debrecen, Hajdú-Bihar, Hungary
|
| 49 |
NCT02656524 |
Completed |
Stivarga Real Life Evidence in Hungary |
|
- Drug: Regorafenib (Stivarga, BAY73-4506)
|
Observational |
|
|
Industry |
- Observational Model: Cohort
- Time Perspective: Retrospective
|
- Length of treatment for each treatment episode
- Progression Free Survival (PFS)
- Overall Survival (OS)
- (and 2 more...)
|
400 |
All |
Child, Adult, Senior |
NCT02656524 |
18686 |
|
July 1, 2016 |
February 15, 2017 |
February 15, 2017 |
January 15, 2016 |
February 12, 2018 |
|
|
| 50 |
NCT02650388 |
Recruiting |
Frailty and Cognitive Function Assessment of TAVI Patients |
- Quality of Life
- Aortic Valve Stenosis
- Heart Valve Disease
|
- Behavioral: Cognitive fuction, quality of life
|
Interventional |
Phase 4 |
- Hungarian Institute of Cardiology
- Semmelweis University
|
Other |
- Intervention Model: Single Group Assignment
- Masking: None (Open Label)
- Primary Purpose: Treatment
|
- To correlate HFS with mortality at 30 days and 1-year
- Find correlation and differences between HFS and QoL
- Find correlation and differences between HFS and eyeball testing
- Find correlation and differences between HFS and cognitive outcomes.
|
100 |
All |
Child, Adult, Senior |
NCT02650388 |
56174-1/2015/EKU(0470/15) |
|
November 2015 |
October 2017 |
October 2018 |
January 8, 2016 |
January 8, 2016 |
|
- Hungarian Institute of Cardiology
Budapest, Hungary
|
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