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The National Library of Medicine (NLM) has launched an effort to modernize to deliver an improved user experience on an updated platform that will accommodate growth and enhance efficiency. This page will be updated as information becomes available related to the Modernization effort.


NLM Board of Regents Public Service Working Group on Modernization

  • The NLM Board of Regents was established to serve as the advisory body to the Secretary, HHS; Assistant Secretary for Health; Director, NIH; and the Director, NLM, on all important aspects of policy regarding the Library and is the final review body for NLM's extramural grant program. The NLM Board of Regents Public Service Working Group on modernization was established September 2019 and relevant meeting materials can be found on the NLM Board of Regents webpage.
  • Working Group Member Bios: Descriptions of the members of the Public Service Working Group on Modernization. (PDF; October, 2021).

Request for Information (RFI)

  • NLM: Summary of Responses to the RFI (PDF; April 28, 2020): This report provides a high-level summary of the responses received for each question posed in the RFI. It also describes the main themes of the suggestions for modernizing Note that NLM did not correct any of the comments or address or comment on their contents. These preliminary analyses will be complemented by additional, in-depth, quantitative and qualitative analyses of the feedback received. NLM will use the input from the RFI, as well as from additional stakeholder engagement, user interviews, and the public meeting on April 30, 2020, to inform its roadmap for modernizing
  • NLM: Public Comments Received in Response to Request for Information (RFI): Modernization (PDF; April 28, 2020): This document consolidates the 268 responses received in response to the RFI without change, including name and affiliation of commenter. The full text of the comments and attachments are listed in the order in which they were received.
  • NLM: Request for Information (RFI): Modernization (December 30, 2019) accepted comments between December 30, 2019 and March 14, 2020.

Beta Release Updates Beta

  • May 9, 2022: Beta has new features, improvements, and fixes as of April 27, 2022. Please see the Release Notes Page to learn more.
  • March 8, 2022: Beta has new features and key improvements such as additional fields on the study record, more prominent publications, study documents when available, and a Release Notes Page for future updates.
  • December 8, 2021: The first release of the Beta website has launched. It includes a responsive site design that better supports mobile-device users and adds information presented in plain language. This release focuses on basic features, with more features to be added over time, based on user input.

PRS Beta

  • May 9, 2022: Updates in PRS Beta, including improvements to functionality of the Record List and additions of helpful tips to the About PRS Beta help document, are now available in the PRS Test System and will be available in the PRS in late May 2022. See the Release Notes Page in PRS Beta under "About" to learn more.
  • January 27, 2022: PRS Beta is now available in the PRS Test system and will be available in the PRS on February 3, 2022. This release consists of new workflow and portfolio management features such as a customizable display and multiple download options to help data submitters save time. A pre-recorded demonstration of this release is also available.


  • Webinar: Modernization Update and Beta Website Demonstration (40:29): This webinar provides an update on the modernization effort and a demonstration of the beta website. Presented by Anna M. Fine, PharmD, MS, Acting Director, and Christina Robinson, MA, Beta Website Product Owner,, NLM. (December 10, 2021)
  • Webinar: Modernization Beta Preview (30:29): This webinar provides an update on modernization efforts and information on the anticipated launch of beta Presented by Rebecca Williams, PharmD, MPH, Acting Director,, NLM. (October 07, 2021)
  • Webinar: Modernization Update (1:02:02): This webinar describes the progress of the modernization effort and what's next. Presented by Rebecca Williams, PharmD, MPH, Acting Director,, NLM. (February 18, 2021)
  • Webinar: Learn About Modernization and How to Provide Input (30:35): This webinar describes the modernization efforts, the Request for Information (RFI), and ways to share your feedback. Presented by Rebecca Williams, PharmD, MPH, Acting Director,, NLM. (January 22, 2020)
  • April 30, 2020 Public Meeting: NLM hosted a virtual public meeting to discuss the topics of interest identified in the Request for Information (RFI) on Modernization and provide opportunities for virtual interaction and clarification of key topics. Presentations recorded from the initial session and two subsequent panels, as described in the meeting agenda (PDF; April 28, 2020), are provided below with running times and PDF handouts for each. A transcript of the entire meeting (PDF; May 28, 2020) is also available.
    • Introduction and Overview Session (55:21)

      Introduction and Overview Session Slides (PDF)


      Summarizes and its modernization effort, NLM's activities in response to the COVID-19 outbreak, and introduces members of the Public Service Working Group on Modernization of the NLM Board of Regents; Provides an overview of the modernization RFI and the most common themes from the 268 responses to the RFI questions. (May 28, 2020)

    • Information Submission Panel (50:57)

      Information Submission Panel slides (PDF)


      Summarizes major themes from RFI comments addressing ways to improve information submission using the Protocol Registration and Results System (PRS) (Topic 2 in RFI) and features presentations from three panelists who highlight diverse perspectives on information submission. (May 28, 2020)

    • Website Functionality Panel (1:06:07)

      Website Functionality Panel slides (PDF)


      Summarizes key trends in RFI responses on the functionality of the website (Topic 1 in RFI) and provides case studies from four panelists on different ways in which the website can be used. (May 28, 2020)

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This page last reviewed in May 2022