Neurotrack Test Validation Protocol
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|ClinicalTrials.gov Identifier: NCT02608021|
Recruitment Status : Completed
First Posted : November 18, 2015
Last Update Posted : December 20, 2019
|Condition or disease|
|Mild Cognitive Impairment|
The Neurotrack test has the potential to dramatically alter the current methods used for detecting cognitive deficits. Patients and research subjects could be screened for medial temporal lobe (MTL) impairment using inexpensive, widely available, safe, and non-invasive technology.
Subjects will be elderly individuals who are participating in ongoing research at the NYU Alzheimer's Disease Center (ADC) and who have received the standard ADC clinical evaluation within the past year, including a medical-neurological evaluation, neuro-psychological assessment and structural neuroimaging (MRI). As part of the current study, all subjects will receive both the Neurotrack Visual Paired-Comparison (VPC) Task and MRI scans. The current protocol strictly for a research study and there will be no "standard care" provided. Participants will be asked to come in for two separate sessions. The first session will involve screening to confirm eligibility and administration of the cognitive testing procedures, while the second session will involve the MRI protocol.
|Study Type :||Observational|
|Actual Enrollment :||81 participants|
|Official Title:||Neurotrack Test Validation Protocol|
|Actual Study Start Date :||October 1, 2015|
|Actual Primary Completion Date :||October 2018|
|Actual Study Completion Date :||October 17, 2018|
|Amnestic mild cognitive impairment|
- Presence of eye fixation assessed by a point of gaze continually remaining within 1 degree of visual angle for a period of 100 milliseconds or more. [ Time Frame: 2 months ]Eye fixation is defined as a point of gaze continually remaining within 1 degree of visual angle for a period of 100 milliseconds or more. Investigators will analyze the fixations that occur within 2 designated areas of interest (AOIs): the area of the novel image and the area of the familiar image.
- Eye tracking data - Total looking time [ Time Frame: 2 months ]Total looking time (i.e. the total sum of the duration for all fixations)
- Eye tracking data - Total number of fixations [ Time Frame: 2 months ]Total number of fixations (i.e. the total number of fixations that met the ≥100 ms criterion)
- Eye tracking data - Percentage looking time [ Time Frame: 2 months ]Percentage looking time on novel image
- Correlation of MRI data with VPC task score [ Time Frame: 2 months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02608021
|United States, New York|
|NYU Langone Medical Center|
|New York, New York, United States, 10016|
|Principal Investigator:||Steven H Ferris||NYU Langone Medical Center|