Study of Megakaryocytes From Patients With Abnormal Platelet Vesicles
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ClinicalTrials.gov Identifier: NCT00086476 |
Recruitment Status :
Completed
First Posted : July 2, 2004
Last Update Posted : July 2, 2017
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Condition or disease |
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Blood Coagulation Disorders |
Study Type : | Observational |
Actual Enrollment : | 3 participants |
Official Title: | Investigations of Megakaryocytes From Patients With Abnormal Platelet Vesicles |
Study Start Date : | June 29, 2004 |
Study Completion Date : | June 13, 2011 |


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Ages Eligible for Study: | 2 Years to 80 Years (Child, Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
- INCLUSION CRITERIA:
This protocol will include children and adults with a clinical diagnosis of GPS, HPS, isolated delta-SPD, combined alpha delta-SPD, Griscelli disease, Chediak Higashi syndrome, Wiskott Aldrich syndrome or Thrombocytopenia absent radius syndrome. Patients whose platelets exhibit abnormal intracellular vesicle morphology will also be eligible.
EXCLUSION CRITERIA:
Patients younger than 2 years and older than 80 years will be excluded. Patients with severe thrombocytopenia (fewer than 20 times 10(12) platelets/L) will be excluded.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00086476
United States, Maryland | |
National Institutes of Health Clinical Center, 9000 Rockville Pike | |
Bethesda, Maryland, United States, 20892 |
ClinicalTrials.gov Identifier: | NCT00086476 |
Other Study ID Numbers: |
040226 04-HG-0226 |
First Posted: | July 2, 2004 Key Record Dates |
Last Update Posted: | July 2, 2017 |
Last Verified: | June 13, 2011 |
Gray Platelet Syndrome Hermansky-Pudlak Syndrome Storage Pool Deficiency Organelle Formation Megakaryocyte Development Megakaryocytes Platelets Dense Granules Alpha Granules Lysosome-related Organelles |
GPS HPS Griscelli Disease Chediak Higashi Syndrome Wiskott Aldrich Syndrome Platelet Congenital Bleeding Disorders SAC Vesicle |
Hemostatic Disorders Blood Coagulation Disorders Hematologic Diseases |
Vascular Diseases Cardiovascular Diseases Hemorrhagic Disorders |