|
Home
Search
Study Topics
Glossary
|
![]() |
![]() |
|
![]() |
|
![]() |
|
![]() |
![]() |
![]() |
|
![]() |
![]() |
||||||||||||||||||||||||||||||||||||
| Sponsored by: |
National Institute of Mental Health (NIMH) |
|---|---|
| Information provided by: | National Institute of Mental Health (NIMH) |
| ClinicalTrials.gov Identifier: | NCT00763581 |
Purpose
This study will attempt to increase understanding of why bipolar disorder patients do or do not take their medications by conducting in-depth interviews with them.
| Condition |
|---|
|
Bipolar Disorder |
| Study Type: | Observational |
| Study Design: | Case-Only, Cross-Sectional |
| Official Title: | Personal Adherence Evaluation of Individuals Receiving Treatment for Bipolar Disorder (PAE in BD) |
| Enrollment: | 20 |
| Study Start Date: | April 2008 |
| Study Completion Date: | January 2009 |
| Primary Completion Date: | November 2008 (Final data collection date for primary outcome measure) |
Disruptive manic and depressive episodes prevent bipolar disorder (BPD) sufferers from living healthy, functional lives. Relapse rates for BPD are high, between 70% and 90%, with approximately half of those relapses occurring in the first 2 years after remission. High rates of relapse and no substantial improvements in illness outcomes for many patients despite advances in drug treatment may be related to a common problem: medication nonadherence. Nine in 10 individuals with BPD have seriously considered medication withdrawal, and one third of individuals with BDP do not take 30% or more of their prescribed medications. The researchers in this study will identify BPD patients who do not take their medications as prescribed and conduct interviews with them. By obtaining an understanding of subjective reasons for medication nonadherence, this study will pave the way for better interventions to ensure BDP patients take the medications that will help them.
Participation in this study will consist of a single visit, lasting between 1.5 and 3 hours. All participants will have a history of medication nonadherence. Participants will be asked to fill out questionnaires and undergo a structured interview with a researcher. The interview will be audio recorded. The questionnaires and interview will assess BPD symptoms, attitudes toward medications, and to what extent patients are taking their medications. Researchers will also measure the number of pills used in participants' prescriptions by counting how many pills are left in each prescription bottle.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Twenty adults (10 men and 10 women) receiving standard outpatient mental health treatment at Connections, a community mental health clinic (CMHC).
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations
More Information
| Responsible Party: | Case Western Reserve University ( Martha Sajatovic, MD ) |
| Study ID Numbers: | R34 MH078967-01, R34 MH078967, DAHBR 96-BHA |
| Study First Received: | September 19, 2008 |
| Last Updated: | February 5, 2009 |
| ClinicalTrials.gov Identifier: | NCT00763581 History of Changes |
| Health Authority: | United States: Federal Government |
|
Patient Non-Adherence Patient Non-Compliance Patient Nonadherence Patient Noncompliance |
Patient Refusal of Treatment Treatment Refusal Refusal of Treatment |
|
Disulfiram Affective Disorders, Psychotic Mental Disorders |
Bipolar Disorder Mood Disorders Psychotic Disorders |
|
Affective Disorders, Psychotic Pathologic Processes Disease |
Mental Disorders Bipolar Disorder Mood Disorders |