Contingency Management for Smoking in Substance Abusers - Full Text View

Sponsor:	University of Connecticut Health Center
Collaborator:	National Institute on Drug Abuse (NIDA)
Information provided by (Responsible Party):	University of Connecticut Health Center
ClinicalTrials.gov Identifier:	NCT00683033

Purpose

Patients (N=102) who meet diagnostic criteria for alcohol, cocaine, marijuana, or opiate abuse or dependence will meet with research staff on two days for quit preparation sessions (2 per day). These sessions include testing a breath sample for evidence of smoking twice each day (separated by at least 5 hours), counseling based on Public Health Service (PHS) guidelines for quitting smoking during the second session each day, and setting a quit date. After these sessions, participants will be randomly assigned to one of two 4-week conditions: (a) standard care or (b) standard care plus prize CM for smoking abstinence with the opportunity to win prizes for submitting samples that meet smoking abstinence criteria (e.g., CO ≤ 6ppm; cotinine ≤ 30ng/mL). Nicotine withdrawal and related measures will be assessed throughout the intervention. Follow-up data will be collected through 6-months post-quit date.

Condition	Intervention	Phase
Cigarette Smoking	Behavioral: Contingency Management Behavioral: Brief smoking cessation counseling	Phase II

Study Type:	Interventional
Study Design:	Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Treatment
Official Title:	Contingency Management for Smoking in Substance Abusers

Resource links provided by NLM:

MedlinePlus related topics: Quitting Smoking Smoking

U.S. FDA Resources

Further study details as provided by University of Connecticut Health Center:

Primary Outcome Measures:

Cigarette smoking abstinence. [ Time Frame: Daily through the 4-week intervention and at follow-up interviews 1, 2, 3, and 6 months following the quit date. ] [ Designated as safety issue: No ]

Enrollment:	51
Study Start Date:	May 2008
Study Completion Date:	October 2010
Primary Completion Date:	October 2010 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
Active Comparator: A Brief counseling based on public health service guidelines.	Behavioral: Brief smoking cessation counseling For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking. Expired carbon monoxide tests are conducted twice daily and urinary cotinine tests are conducted once each week.
Experimental: B Brief counseling based on public health service guidelines for quitting smoking plus prize-based contingency management	Behavioral: Contingency Management For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking is delivered. Expired carbon monoxide (CO) tests are conducted twice daily and urinary cotinine tests are conducted once each week. Participants earn the opportunity to win prizes for submitting samples that meet smoking abstinence criteria (e.g., CO ≤ 6ppm; cotinine ≤ 30ng/mL). Behavioral: Brief smoking cessation counseling For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking. Expired carbon monoxide tests are conducted twice daily and urinary cotinine tests are conducted once each week.

Arms

Assigned Interventions

Active Comparator: A

Brief counseling based on public health service guidelines.

Behavioral: Brief smoking cessation counseling

For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking. Expired carbon monoxide tests are conducted twice daily and urinary cotinine tests are conducted once each week.

Experimental: B

Brief counseling based on public health service guidelines for quitting smoking plus prize-based contingency management

Behavioral: Contingency Management

For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking is delivered. Expired carbon monoxide (CO) tests are conducted twice daily and urinary cotinine tests are conducted once each week. Participants earn the opportunity to win prizes for submitting samples that meet smoking abstinence criteria (e.g., CO ≤ 6ppm; cotinine ≤ 30ng/mL).

Behavioral: Brief smoking cessation counseling

For 4 weeks starting on the quit date, daily brief (about 5 minutes) counseling based on public health service guidelines for quitting smoking. Expired carbon monoxide tests are conducted twice daily and urinary cotinine tests are conducted once each week.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

current alcohol, cocaine, marijuana, or opiate abuse or dependence
smoke ≥ 10 cigarettes per day
expired CO > 8 ppm
self-reported interest in quitting smoking,
≥ 18 years old
willing to provide names, addresses and phone numbers of individuals to assist in locating the participant for follow-up evaluations,
English speaking

Exclusion Criteria:

currently receiving behavioral therapy or pharmacotherapy for smoking plan to use pharmacotherapy in this quit attempt
serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, suicide risk)
cognitive impairment
in recovery for pathological gambling

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00683033

Locations

United States, Connecticut
University of Connecticut Health Center
Farmington, Connecticut, United States, 06030

Sponsors and Collaborators

University of Connecticut Health Center

National Institute on Drug Abuse (NIDA)

Investigators

Principal Investigator:

Sheila M Alessi, Ph.D.

University of Connecticut Health Center

More Information

No publications provided

Responsible Party:	University of Connecticut Health Center
ClinicalTrials.gov Identifier:	NCT00683033 History of Changes
Other Study ID Numbers:	08-081-2, R21DA021836-01A2
Study First Received:	May 14, 2008
Last Updated:	November 17, 2011
Health Authority:	United States: Institutional Review Board

Keywords provided by University of Connecticut Health Center:

Contingency Management
Cigarette Smoking Cessation
Substance Abusers

Additional relevant MeSH terms:

Smoking
Habits

ClinicalTrials.gov processed this record on February 09, 2012