Environmental Pollutants and the Risk of Soft Tissue Sarcoma: A Pilot Study

This study has been completed.

First Received on January 25, 2008. Last Updated on January 19, 2011 History of Changes

Sponsor:	Memorial Sloan-Kettering Cancer Center
Information provided by:	Memorial Sloan-Kettering Cancer Center
ClinicalTrials.gov Identifier:	NCT00611078

Purpose

The purpose of this study is to assess the feasibility of conducting a large hospital based case control study of the role of dioxins and dioxinlike polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs).

Condition
Soft Tissue Sarcoma

Study Type:	Observational
Study Design:	Observational Model: Case Control Time Perspective: Prospective
Official Title:	Environmental Pollutants and the Risk of Soft Tissue Sarcoma: A Pilot Study

Resource links provided by NLM:

MedlinePlus related topics: Cancer Soft Tissue Sarcoma

U.S. FDA Resources

Further study details as provided by Memorial Sloan-Kettering Cancer Center:

Primary Outcome Measures:

enrollment of 60 participants [ Time Frame: Conclusion of the study ] [ Designated as safety issue: No ]

Biospecimen Retention: Samples With DNA

blood, adipose tissue

Enrollment:	56
Study Start Date:	September 2004
Study Completion Date:	January 2011
Primary Completion Date:	January 2011 (Final data collection date for primary outcome measure)

Eligibility

Ages Eligible for Study:	18 Years to 79 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

Patients with Soft Tissue Sarcoma at Memorial Sloan Kettering Cancer Center.

Criteria

Inclusion Criteria:

Patients with Soft tissue sarcoma at MSKCC are eligible for this study if they meet the following criteria:
Between 18 and 79 years of age
were diagnosed within the previous 6 months with primary soft tissue sarcoma of one of the following histologic subtypes: liposarcoma, leiomyoscaroma, MFH, or synovial sarcoma
are enrolled in protocol 02-060 ("Novel Biochemical and Molecularr Determinants for Soft Tissue Sarcoma"; PI, Dr. Samuel Singer)
controls will be eligibile for this study if they meet the following criteria
are b/w 18-79 years of age
have no prior history of cancer (other than non melanoma skin cancer)

Exclusion Criteria:

Individuals will be excluded if they
are unable to sign informed consent for medical or other reasons
do not speak english

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00611078

Locations

United States, New York
Memorial Sloan-Kettering Cancer Center
New York, New York, United States, 10021

Sponsors and Collaborators

Memorial Sloan-Kettering Cancer Center

Investigators

Principal Investigator:

Lawrence Engel, Ph.D.

Memorial Sloan-Kettering Cancer Center

More Information

No publications provided

Responsible Party:	Engel, Lawrence Stuart, PhD, Memorial Sloan-Kettering Cancer Center
ClinicalTrials.gov Identifier:	NCT00611078 History of Changes
Other Study ID Numbers:	04-088
Study First Received:	January 25, 2008
Last Updated:	January 19, 2011
Health Authority:	United States: Institutional Review Board

Keywords provided by Memorial Sloan-Kettering Cancer Center:

Soft Tissue Sarcoma
environment
pollutants
04-088

Additional relevant MeSH terms:

Sarcoma
Neoplasms, Connective and Soft Tissue
Neoplasms by Histologic Type
Neoplasms

ClinicalTrials.gov processed this record on February 09, 2012