AIDS and Cancer Specimen Bank (ACSB) - Full Text View

Sponsor:	Memorial Sloan-Kettering Cancer Center
Collaborators:	National Cancer Institute (NCI) George Washington University University of Hawaii University of California, San Francisco Kaiser Permanente
Information provided by:	Memorial Sloan-Kettering Cancer Center
ClinicalTrials.gov Identifier:	NCT00587912

Purpose

The purpose of this study is to obtain clinical specimens from pathologists and physicians involved in the diagnosis and care of patients with AIDS and non-AIDS associated malignancies.

The National Cancer Institute has set up a Bank for tissues and biological fluids from HIVpositive and HIV-negative individuals in order to have specimens available for scientists studying malignancies associated with HIV disease.

Condition
Kaposi's Sarcoma AIDS Related Kaposi's Sarcoma Classical Non-Hodgkin's Lymphoma HEMATOPOIETIC SYSTEM Cancer AIDS

Study Type:	Observational
Study Design:	Observational Model: Case-Only Time Perspective: Prospective
Official Title:	AIDS and Cancer Specimen Bank (ACSB)

Resource links provided by NLM:

Genetics Home Reference related topics: complement factor I deficiency

MedlinePlus related topics: Cancer HIV/AIDS Kaposi's Sarcoma Lymphoma Soft Tissue Sarcoma

U.S. FDA Resources

Further study details as provided by Memorial Sloan-Kettering Cancer Center:

Primary Outcome Measures:

Identify and improve access to tumor tissue, biological specimens, and associated clinical outcome data that could be utilized for research by the research community at-large on the pathogenesis of HIV and non-HIV associated malignancies. [ Time Frame: 3 years ] [ Designated as safety issue: No ]

Biospecimen Retention: Samples With DNA

Blood, urine, other bodily fluids (eg, pleural fluid), and tumor tissue obtained from patients.

Enrollment:	65
Study Start Date:	June 1997
Study Completion Date:	April 2011
Primary Completion Date:	April 2011 (Final data collection date for primary outcome measure)

Detailed Description:

The overall goal of the AIDS and Cancer Specimen Bank is to obtain clinical specimens from pathologists and physicians involved in the diagnosis and care of patients with AIDS and non- AIDS associated malignancies. These specimens will be banked and linked to a clinical data set so that experimental results obtained by analysis of specific specimens can be linked to relevant clinical data. Contents of the ACSB will be made available to researchers through an application to the National Cancer Institute. Strict patient confidentiality protection guidelines are in place for all specimens in the ACSB. The objective of this protocol is to obtain clinical specimens from potential participants in clinical trials conducted by the AIDS Malignancies Consortium, and from other patients with and without HIV infection, who have AIDS-Associated malignancies.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

The Source of specimens will include patients screened for participation on protocols conducted by the AIDS Malignancy Consortium, as well as other patients with HIV infection and cancer who are not eligible for participation in AMC trials, and patients without HIV who have malignancies associated with HIV or with immunosuppression.

Criteria

Inclusion Criteria:

Patient > 18 years of age
Suspected or confirmed AIDS-Associated malignancy with or without HIV infection
Will obtain fresh tissue and/or biological fluids
Patient signed the correct version of the informed consent

Exclusion Criteria:

N/A

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00587912

Locations

United States, New York
Memorial Sloan-Kettering Cancer Center
New York, New York, United States, 10065

Sponsors and Collaborators

Memorial Sloan-Kettering Cancer Center

National Cancer Institute (NCI)

George Washington University

University of Hawaii

University of California, San Francisco

Kaiser Permanente

Investigators

Principal Investigator:

David Straus, MD

Memorial Sloan-Kettering Cancer Center

More Information

Additional Information:

Memorial Sloan-Kettering web site This link exits the ClinicalTrials.gov site

No publications provided

Responsible Party:	David Straus, MD, Memorial Sloan-Kettering Cancer Center
ClinicalTrials.gov Identifier:	NCT00587912 History of Changes
Other Study ID Numbers:	97-043
Study First Received:	December 24, 2007
Last Updated:	April 20, 2011
Health Authority:	United States: Institutional Review Board

Keywords provided by Memorial Sloan-Kettering Cancer Center:

Kaposi's Sarcoma AIDS Related
Kaposi's Sarcoma Classical
Non-Hodgkin's Lymphoma

HEMATOPOIETIC SYSTEM
Cancer
AIDS

Additional relevant MeSH terms:

Acquired Immunodeficiency Syndrome
HIV Infections
Lymphoma
Lymphoma, Non-Hodgkin
Sarcoma, Kaposi
AIDS-Related Opportunistic Infections
Sarcoma
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Slow Virus Diseases

Immunologic Deficiency Syndromes
Immune System Diseases
Neoplasms by Histologic Type
Neoplasms
Lymphoproliferative Disorders
Lymphatic Diseases
Immunoproliferative Disorders
Herpesviridae Infections
DNA Virus Infections
Neoplasms, Connective and Soft Tissue
Neoplasms, Vascular Tissue
Opportunistic Infections
Infection
Parasitic Diseases

ClinicalTrials.gov processed this record on February 09, 2012