Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients

This study has been completed.

First Received on August 7, 2007. No Changes Posted

Sponsor:	Baqiyatallah Medical Sciences University
Information provided by:	Baqiyatallah Medical Sciences University
ClinicalTrials.gov Identifier:	NCT00512811

Purpose

to assess the efficacy of inhaled furosemide in mustard gas exposed patients with acute respiratory failure

Condition	Intervention	Phase
Bronchiolitis	Drug: furosemide	Phase III

Study Type:	Interventional
Study Design:	Allocation: Randomized Intervention Model: Crossover Assignment Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor) Primary Purpose: Supportive Care
Official Title:	Furosemide Inhalation in Dyspnea of Mustard Gas Exposed Patients: a Double-Blind Randomized Study

Resource links provided by NLM:

MedlinePlus related topics: Breathing Problems Gas

Drug Information available for: Mechlorethamine Furosemide Mechlorethamine hydrochloride Mustard gas

U.S. FDA Resources

Further study details as provided by Baqiyatallah Medical Sciences University:

Primary Outcome Measures:

effect of furosemid inhalation on dyspnea

Eligibility

Ages Eligible for Study:	32 Years to 83 Years
Genders Eligible for Study:	Male

Criteria

Inclusion Criteria:

Patients with a history of exposure to sulfur mustard with a complaint of dyspnea

Exclusion Criteria:

A contraindication for furosemide use;
An accompanying disease in which other drugs effective for dyspnea were used

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00512811

Locations

Iran, Islamic Republic of
RCCI
Tehran, Iran, Islamic Republic of

Sponsors and Collaborators

Baqiyatallah Medical Sciences University

Investigators

Study Chair:

Mostafa Ghanei, MD

Research Center of Chemical Injuries, Baqiyatallah Medical Science University, Tehran, Iran

More Information

No publications provided

ClinicalTrials.gov Identifier:	NCT00512811 History of Changes
Other Study ID Numbers:	121a25
Study First Received:	August 7, 2007
Last Updated:	August 7, 2007
Health Authority:	Iran: Ethics Committee

Keywords provided by Baqiyatallah Medical Sciences University:

furosemide
inhalation
dyspnea
spirometry

mustard gas
bronchiolitis
sulfur mustard

Additional relevant MeSH terms:

Respiratory Aspiration
Bronchiolitis
Dyspnea
Respiration Disorders
Respiratory Tract Diseases
Signs and Symptoms, Respiratory
Signs and Symptoms
Bronchitis
Bronchial Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Tract Infections

Furosemide
Mustard Gas
Sodium Potassium Chloride Symporter Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Diuretics
Natriuretic Agents
Physiological Effects of Drugs
Cardiovascular Agents
Therapeutic Uses
Dermatologic Agents

ClinicalTrials.gov processed this record on February 09, 2012