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| Sponsor: | Institut de Recherches Cliniques de Montreal |
|---|---|
| Information provided by: | Institut de Recherches Cliniques de Montreal |
| ClinicalTrials.gov Identifier: | NCT00208221 |
Purpose
The purpose of this study is to determine if a dose of ramipril combined with a normal dose of telmisartan 80 mg will be more effective than ramipril 20 mg in reducing microalbuminuria in hypertensive patients with diabetes.
| Condition | Intervention | Phase |
|---|---|---|
|
Hypertension Type 2 Diabetes Albuminuria |
Drug: ramipril Drug: ramipril-telmisartan |
Phase III |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Treatment |
| Official Title: | Comparison of a Higher Dose of Ramipril to the Addition of Telmisartan 80 mg+Ramipril 10 mg in Patients With Hypertension and Diabetes |
| Estimated Enrollment: | 50 |
| Study Start Date: | August 2006 |
| Study Completion Date: | June 2007 |
The purpose of this study is to determine the effects of ramipril 10 mg and telmisartan 80 mg versus ramipril 20 mg in patients with diabetes type II, hypertension and microalbuminuria (Urinary-albuminuria creatinine ratio of 2.0 to 25 mg/mmol) on
Eligibility| Ages Eligible for Study: | 18 Years to 80 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Canada, Quebec | |
| Institut de Recherches Cliniques de Montreal | |
| Montreal, Quebec, Canada, J4X 1J3 | |
| Principal Investigator: | Pierre Larochelle, MD PhD FRCPC | Institut de Recherches Cliniques de Montreal |
More Information
| ClinicalTrials.gov Identifier: | NCT00208221 History of Changes |
| Other Study ID Numbers: | RD 0507/17259 |
| Study First Received: | September 13, 2005 |
| Last Updated: | November 7, 2007 |
| Health Authority: | Canada: Health Canada |
|
Hypertension Diabetes Microalbuminuria Blood pressure |
|
Albuminuria Diabetes Mellitus Diabetes Mellitus, Type 2 Hypertension Proteinuria Urination Disorders Urologic Diseases Urological Manifestations Signs and Symptoms Glucose Metabolism Disorders Metabolic Diseases Endocrine System Diseases Vascular Diseases |
Cardiovascular Diseases Ramipril Telmisartan Angiotensin-Converting Enzyme Inhibitors Protease Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action Pharmacologic Actions Antihypertensive Agents Cardiovascular Agents Therapeutic Uses Angiotensin II Type 1 Receptor Blockers Angiotensin Receptor Antagonists |