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| Sponsor: | West Penn Allegheny Health System |
|---|---|
| Collaborator: |
Aventis Pharmaceuticals |
| Information provided by: | West Penn Allegheny Health System |
| ClinicalTrials.gov Identifier: | NCT00189449 |
Purpose
Seasonal/perennial allergic rhinitis (SAR/PAR) is a common childhood illness. One of the leading therapies for the treatment of SAR/PAR is intranasally inhaled corticosteroids (ICS). One of the major long-term safety concerns is whether ICS interferes with normal growth in allergic rhinitis children. Recent evidence suggests that nasal ICS may cause decreased growth. However, the effect of nasal ICS on long-term growth and the attainment of final adult height is unknown. Another potential systemic adverse effect of ICS use is suppression of the hypothalamic-pituitary-adrenal axis function. The primary hypothesis of this study is that triamcinolone acetonide aqueous nasal spray (TAA) will have no effect on measured adult height in relation to target adult height in children with allergic rhinitis.
| Study Type: | Observational |
| Official Title: | Effects of Long-Term Treatment With Nasally Inhaled Triamcinolone Acetonide in Children With Allergic Rhinitis |
Eligibility| Ages Eligible for Study: | 6 Years to 13 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| United States, Pennsylvania | |
| Allegheny General Hospital | |
| Pittsburgh, Pennsylvania, United States, 15212 | |
| Principal Investigator: | David Skoner, MD | West Penn Allegheny Health System |
More Information
| ClinicalTrials.gov Identifier: | NCT00189449 History of Changes |
| Other Study ID Numbers: | IST Nasacort AQ NAS.US1.631, RC - 3421 |
| Study First Received: | September 12, 2005 |
| Last Updated: | April 30, 2008 |
| Health Authority: | United States: Institutional Review Board |
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Allergic Rhinitis Allergy Growth |
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Hypersensitivity Rhinitis Immune System Diseases Nose Diseases Respiratory Tract Diseases Respiratory Tract Infections Otorhinolaryngologic Diseases Triamcinolone hexacetonide Triamcinolone Acetonide Triamcinolone Triamcinolone diacetate |
Anti-Inflammatory Agents Therapeutic Uses Pharmacologic Actions Glucocorticoids Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Physiological Effects of Drugs Immunosuppressive Agents Immunologic Factors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action |