High Intensity Light Therapy in Alzheimer's Disease

This study has been completed.

First Received on July 31, 2003. Last Updated on July 24, 2006 History of Changes

Sponsor:	National Center for Complementary and Alternative Medicine (NCCAM)
Information provided by:	National Center for Complementary and Alternative Medicine (NCCAM)
ClinicalTrials.gov Identifier:	NCT00065689

Purpose

The purpose of this study is to determine whether bright light improves the sleep, mood, and behavior of persons with Alzheimer's disease and related dementias (AD) who live in long-term care settings and, if so, to determine the best timing for the light therapy. The light levels being used in the study have been shown to improve depression in persons with seasonal affective disorder (SAD) and to relieve sleep problems in persons with jet lag and other body rhythm disturbances. Because persons with AD often will not remain still in front of a fluorescent panel, this project has involved renovations in the study units that provide for even, regulated, high-intensity light in all public areas of the study settings.

Condition	Intervention	Phase
Alzheimer's Disease Dementia	Device: high-intensity light therapy	Phase III

Study Type:	Interventional
Study Design:	Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Crossover Assignment Masking: Single Blind Primary Purpose: Treatment
Official Title:	High Intensity Light Therapy in Alzheimer's Disease

Resource links provided by NLM:

Genetics Home Reference related topics: Alzheimer disease

MedlinePlus related topics: Alzheimer's Disease Dementia Depression

U.S. FDA Resources

Further study details as provided by National Center for Complementary and Alternative Medicine (NCCAM):

Estimated Enrollment:	107
Study Start Date:	March 2003
Estimated Study Completion Date:	September 2005

Detailed Description:

See Brief Summary

Eligibility

Ages Eligible for Study:	55 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion criteria:

Diagnosis of dementia
Residence on study units

Exclusion criteria:

Bipolar disorder
Severe retinal (eye) disease

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00065689

Locations

United States, North Carolina
John Umstead Hospital
Butner, North Carolina, United States, 27514

Sponsors and Collaborators

National Center for Complementary and Alternative Medicine (NCCAM)

Investigators

Principal Investigator:

Philip D. Sloane, MD, MPH

More Information

No publications provided

ClinicalTrials.gov Identifier:	NCT00065689 History of Changes
Other Study ID Numbers:	R01 AT000212-01A1, SloaneP
Study First Received:	July 31, 2003
Last Updated:	July 24, 2006
Health Authority:	United States: Federal Government

Keywords provided by National Center for Complementary and Alternative Medicine (NCCAM):

Alzheimer's disease
light therapy
long-term care

depression
sleep
agitation

Additional relevant MeSH terms:

Alzheimer Disease
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases

Tauopathies
Neurodegenerative Diseases
Delirium, Dementia, Amnestic, Cognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on February 09, 2012