DISEASE CHARACTERISTICS:

• Histologically confirmed endometrial papillary carcinoma (uterine papillary serous carcinoma)

  • Progressive or recurrent
• Bidimensionally measurable disease

• Platinum refractory disease, defined by one of the following:

  • Progression during platinum-based chemotherapy
  • Stable disease for at least 4 courses of platinum-based chemotherapy
  • Recurrence within 4 months of platinum-based chemotherapy
• No brain involvement or leptomeningeal disease

PATIENT CHARACTERISTICS:

Age:

• 75 and under

Performance status:

• WHO 0-2

Life expectancy:

• Not specified

Hematopoietic:

• Neutrophil count at least 1,500/mm3
• Platelet count at least 100,000/mm3

Hepatic:

• Bilirubin no greater than 50 umol/L

Renal:

• BUN no greater than 8.0 mmol/L
• Creatinine no greater than 120 umol/L
• Creatinine clearance at least 60 mL/min

Other:

• Not pregnant
• Fertile patients must use effective contraception
• HIV negative
• No other prior or concurrent malignancy except basal cell carcinoma of the skin
• No active bacterial infection (e.g., urinary tract infection)
• No uncontrolled or potentially active site of infection (e.g., fistula or abscess)
• No psychological, familial, sociological, or geographical condition that would preclude study

PRIOR CONCURRENT THERAPY:

Biologic therapy:

• Not specified

Chemotherapy:

• See Disease Characteristics
• At least 4 weeks since prior chemotherapy
• At least 1 prior platinum containing regimen
• At least 50 mg/m2 per course for a maximum of 28 days for cisplatin
• At least 5 times AUC for a maximum of 4 weeks per course for carboplatin
• Prior non-taxane-containing chemotherapy allowed

Endocrine therapy:

• At least 4 weeks since prior hormonal therapy

Radiotherapy:

• At least 4 weeks since prior radiotherapy
• At least 3 months since prior radiotherapy to target lesion
• Concurrent radiotherapy allowed for bone pain provided evaluable lesions are outside of irradiation field)

Surgery:

• Prior surgical management of lymph nodes allowed