Depot Disulfiram for AIDS and ARC

This study has been completed.

First Received on November 2, 1999. Last Updated on June 23, 2005 History of Changes

Sponsor:	St. Vincent's Medical Center
Information provided by:	NIH AIDS Clinical Trials Information Service
ClinicalTrials.gov Identifier:	NCT00002065

Purpose

To assess the safety and efficacy of depot disulfiram as a new treatment for AIDS and AIDS related complex.

Condition	Intervention
HIV Infections	Drug: Disulfiram

Study Type:	Interventional
Study Design:	Masking: Open Label Primary Purpose: Treatment
Official Title:	Depot Disulfiram for AIDS and ARC

Resource links provided by NLM:

Genetics Home Reference related topics: complement factor I deficiency

MedlinePlus related topics: HIV/AIDS

Drug Information available for: Disulfiram

U.S. FDA Resources

Further study details as provided by NIH AIDS Clinical Trials Information Service:

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria

Patients must have a positive diagnosis of AIDS or AIDS related complex (ARC) according to the CDC criteria.

Also patient must be:
Able to understand the study.
Strongly motivated to participate in the study, and willing to comply with all the conditions specified in the informed consent forms.
Ambulatory and able to maintain an independent life outside the hospital.
Free of clinically significant organic disease affecting neurologic, hepatic, renal, and clinical status.

Patients must be free of clinically significant organic disease affecting neurologic, hepatic, renal, and clinical status.

History of alcohol abuse.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00002065

Locations

United States, New York
Saint Vincent's Med Ctr
Staten Island, New York, United States, 10310

Sponsors and Collaborators

St. Vincent's Medical Center

More Information

No publications provided

ClinicalTrials.gov Identifier:	NCT00002065 History of Changes
Other Study ID Numbers:	024A
Study First Received:	November 2, 1999
Last Updated:	June 23, 2005
Health Authority:	United States: Food and Drug Administration

Keywords provided by NIH AIDS Clinical Trials Information Service:

Delayed-Action Preparations
Disulfiram
Acquired Immunodeficiency Syndrome
AIDS-Related Complex

Additional relevant MeSH terms:

HIV Infections
Acquired Immunodeficiency Syndrome
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes

Immune System Diseases
Slow Virus Diseases
Disulfiram
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Pharmacologic Actions
Alcohol Deterrents
Central Nervous System Agents
Therapeutic Uses

ClinicalTrials.gov processed this record on February 12, 2012