Assessment of a B-Mode Ultrasound Technique for the Measurement of Carotid Artery Intima-Media Thickness

This study has been completed.

First Received on November 3, 1999. Last Updated on March 3, 2008 History of Changes

Sponsor:	National Institute of Allergy and Infectious Diseases (NIAID)
Information provided by:	National Institutes of Health Clinical Center (CC)
ClinicalTrials.gov Identifier:	NCT00001904

Purpose

This minimal risk protocol is designed to assess the reproducibility of B-mode ultrasound measurements of carotid intima media thickness (IMT) when the scans are performed in CC Radiology and read using a computerized edge reader. Up to 20 volunteers will have two ultrasounds performed within a 6-month period. IMT thickness is used as a surrogate marker for atherosclerosis and may be of value in clinical trials.

Condition
Atherosclerosis Myocardial Infarction

Study Type:	Observational
Official Title:	Assessment of a B-Mode Ultrasound Technique for the Measurement of Carotid Artery Intima-Media Thickness

Resource links provided by NLM:

MedlinePlus related topics: Atherosclerosis Heart Attack Ultrasound

U.S. FDA Resources

Further study details as provided by National Institutes of Health Clinical Center (CC):

Estimated Enrollment:	50
Study Start Date:	April 1999
Estimated Study Completion Date:	September 2000

Detailed Description:

This minimal risk protocol is designed to assess the reproducibility of B-mode ultrasound measurements of carotid intima-media thickness (IMT) when the scans are performed in CC Radiology and read using a computerized edge reader. Up to 50 volunteers will have two ultrasounds performed within a 6-month period. IMT thickness is used as a surrogate marker for atherosclerosis and may be of value in clinical trials.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Adult (age 18 or older).

Desire to participate in the study; willing and able to provide informed consent.

No history of stroke or carotid disease.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00001904

Locations

United States, Maryland
National Institute of Allergy and Infectious Diseases (NIAID)
Bethesda, Maryland, United States, 20892

Sponsors and Collaborators

National Institute of Allergy and Infectious Diseases (NIAID)

More Information

Publications:

Tan GH, Gharib H. Thyroid incidentalomas: management approaches to nonpalpable nodules discovered incidentally on thyroid imaging. Ann Intern Med. 1997 Feb 1;126(3):226-31. Review.

Mercuri M. Noninvasive imaging protocols to detect and monitor carotid atherosclerosis progression. Am J Hypertens. 1994 Jul;7(7 Pt 2):23S-29S. Review.

ClinicalTrials.gov Identifier:	NCT00001904 History of Changes
Other Study ID Numbers:	990085, 99-I-0085
Study First Received:	November 3, 1999
Last Updated:	March 3, 2008
Health Authority:	United States: Federal Government

Keywords provided by National Institutes of Health Clinical Center (CC):

Atherosclerosis
Cardiovascular Disease
Computerized Edge Reader
Myocardial Infarction
Risk Factor

Additional relevant MeSH terms:

Atherosclerosis
Infarction
Myocardial Infarction
Arteriosclerosis
Arterial Occlusive Diseases
Vascular Diseases

Cardiovascular Diseases
Ischemia
Pathologic Processes
Necrosis
Myocardial Ischemia
Heart Diseases

ClinicalTrials.gov processed this record on February 12, 2012