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Found 164 studies with search of: Diffuse Sclerosis
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Rank Status Study
1 Unknown † High Dose Cyclophosphamide for Treatment of Scleroderma
Condition: Scleroderma
Intervention: Drug: High Dose Cyclophosphamide
2 Completed Efficacy and Safety of Imatinib in Scleroderma
Conditions: Scleroderma, Localized;   Scleroderma, Systemic
Intervention: Drug: imatinib mesylate
3 Recruiting Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic Sclerosis
Conditions: Systemic Sclerosis;   Scleroderma
Intervention: Drug: Ambrisentan with an anti-fibrotic agent to assess benefit on skin.
4 Recruiting Neuropsychiatric Scleroderma Study: Systematic Evaluation of Neuropsychiatric Involvement in Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention: Other: Magnetic resonance Imaging
5 Recruiting Comparison of Therapeutic Regimens for Scleroderma Interstitial Lung Disease (The Scleroderma Lung Study II)
Conditions: Scleroderma;   Interstitial Lung Disease
Interventions: Drug: Mycophenolate mofetil;   Drug: Cyclophosphamide;   Drug: Placebo
6 Active, not recruiting Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine
Conditions: Systemic Sclerosis;   Scleroderma
Interventions: Drug: treprostinil diethanolamine;   Drug: placebo
7 Completed Sleep Disturbances and Pulmonary Artery/Aorta Diameter in Scleroderma Patient
Conditions: Scleroderma;   Pulmonary Hypertension
Intervention:
8 Completed A Study to Evaluate the Safety and Efficacy of Abatacept in Patients With Diffuse Systemic Sclerosis (Scleroderma)
Conditions: Scleroderma, Diffuse;   Scleroderma, Systemic
Intervention: Drug: Abatacept
9 Recruiting Fludarabine Phosphate and Total-Body Irradiation Followed By Donor Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Severe Systemic Sclerosis
Condition: Systemic Sclerosis
Interventions: Drug: fludarabine phosphate;   Drug: mycophenolate mofetil;   Drug: tacrolimus;   Radiation: total-body irradiation;   Procedure: peripheral blood stem cell transplantation;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation;   Procedure: quality-of-life assessment;   Other: laboratory biomarker analysis;   Other: flow cytometry;   Procedure: biopsy;   Procedure: allogeneic bone marrow transplantation
10 Unknown † High Dose Intravenous N-Acetylcysteine Versus Iloprost for Early, Rapidly Progressive Diffuse Systemic Sclerosis
Condition: Scleroderma, Diffuse
Intervention: Drug: N-acetylcysteine (NAC)
11 Completed Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis
Conditions: Systemic Scleroderma;   Skin Fibrosis;   Hand Functionality
Intervention: Drug: Bosentan (Tracleer)
12 Active, not recruiting AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis
Condition: Systemic Sclerosis
Interventions: Drug: Hyperimmune caprine serum;   Drug: Albumin
13 Suspended Effect of Bosentan in Scleroderma Renal Crisis
Condition: Scleroderma Renal Crisis
Intervention: Drug: Bosentan
14 Terminated Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients
Conditions: Scleroderma;   Systemic Sclerosis
Interventions: Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: Thymoglobulin;   Procedure: Leukapheresis;   Procedure: Self bone marrow transplant
15 Unknown † Genesis of Scleroderma: Role of Environmental Factors in 100 Patients With Scleroderma and 300 Controls
Condition: Scleroderma
Intervention:
16 Completed Pharmacokinetics of Oral Treprostinil in Patients With Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention: Drug: treprostinil diethanolamine
17 Active, not recruiting Imatinib Mesylate (Gleevec) in the Treatment of Systemic Sclerosis
Condition: Systemic Sclerosis
Intervention: Drug: Imatinib Mesylate
18 Active, not recruiting Scleroderma: Cyclophosphamide or Transplantation (SCOT)
Conditions: Scleroderma, Systemic;   Sclerosis;   Autoimmune Disease
Interventions: Procedure: Autologous stem cell transplantation and High-dose immunosuppressive therapy (HDIT);   Drug: Cyclosphosphamide;   Drug: Equine antithymocyte globulin;   Drug: Methylprednisolone;   Drug: Growth colony stimulating factor (G-CSF);   Radiation: Total body irradiation (TBI)
19 Completed Pulmonary Involvement in Scleroderma: A Clinical Study of the Safety and Efficacy of Mycophenolate Mofetil in Scleroderma Patients With Lung Involvement
Condition: Scleroderma, Systemic
Intervention: Drug: mycophenolate mofetil
20 Recruiting Autologous Stem Cell Systemic Sclerosis Immune Suppression Trial
Condition: Scleroderma
Interventions: Procedure: Rituximab sandwich regiment followed by SCT;   Procedure: cyclophosphamide regiment followed by SCT

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