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Found 16 studies with search of: Open Studies | "Poxviridae Infections"
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Rank Status Study
1 Recruiting Safety Study of Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma
Condition: Carcinoma, Colorectal
Intervention: Drug: Recombinant Vaccinia GM-CSF; RAC VAC GM-CSF (JX-594)
2 Recruiting Safety Surveillance Study of ACAM2000® Vaccinia Vaccine
Condition: Smallpox
Intervention:
3 Recruiting Safety of and Immune Response to a DNA HIV Vaccine Boosted With a Modified Vaccinia HIV Vaccine and Protein HIV Vaccine in Healthy Adults
Conditions: HIV Seronegativity;   HIV Preventive Vaccine
Interventions: Biological: MVA-C + gp140/MF59;   Biological: DNA-C2 + MVA-C;   Biological: DNA-C2 + MVA-C + gp140/MF59
4 Not yet recruiting A Study to Evaluate Immunogenicity and Safety of Three Consecutive Production Lots of IMVAMUNE® (MVA-BN®) Smallpox Vaccine in Healthy, Vaccinia-naïve Subjects
Condition: Smallpox
Interventions: Biological: IMVAMUNE;   Other: Placebo
5 Recruiting Recombinant Vaccinia Virus Administered Intravenously Followed by Intratumoral Boosts in Patients With Metastatic, Refractory Colorectal Carcinoma
Conditions: Colorectal Carcinoma;   CRC
Interventions: Biological: JX-594;   Drug: Irinotecan
6 Unknown † Safety and Efficacy of CJ-50300 in Healthy Volunteers
Condition: Smallpox
Intervention: Biological: smallpox vaccine CJ-50300
7 Recruiting A Study of Recombinant Vaccinia Virus Prior to Sorafenib to Treat Unresectable Primary Hepatocellular Carcinoma
Condition: Carcinoma, Hepatocellular
Intervention: Drug: JX-594 followed by sorafenib
8 Recruiting A Phase 2b Study of Modified Vaccinia Virus to Treat Advanced Liver Cancer
Conditions: Hepatocellular Carinoma;   Liver Cancer;   HCC
Interventions: Biological: JX-594 recombinant vaccina GM-CSF;   Other: Best Supportive Care
9 Not yet recruiting A Study of GL-ONC1, an Oncolytic Vaccinia Virus, in Patients With Advanced Peritoneal Carcinomatosis
Condition: Peritoneal Carcinomatosis
Intervention: Biological: GL-ONC1
10 Recruiting Immune Responses to Smallpox Vaccination
Condition: Smallpox Vaccine
Intervention:
11 Recruiting Safety Study of Modified Vaccinia Virus to Cancer
Conditions: Melanoma;   Breast Cancer;   Head and Neck Squamous Cell Cancer;   Hepatocellular Cancer;   Colorectal Cancer;   Pancreatic Adenocarcinoma
Intervention: Biological: Vaccinia virus (vvDD-CDSR)
12 Recruiting Safety Surveillance Cohort Study of Vaccinia Vaccine (ACAM2000®)
Condition: Smallpox
Intervention:
13 Recruiting A Multicenter, Open-label Study of CMX001 Treatment of Serious Diseases or Conditions Caused by dsDNA Viruses
Conditions: Male or Female Patients With a Serious or Immediately Life-threatening;   Disease or Condition Caused by CMV, ADV, HSV, VAVC, VARV or;   Monkeypox Viruses(s) Who Have a Life Expectancy of ≥ 2 Weeks and for;   Whom no Comparable or Satisfactory Alternative Therapy is Available
Intervention: Drug: CMX001
14 Recruiting Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients
Conditions: Neuroblastoma;   Rhabdomyosarcoma;   Lymphoma;   Wilm's Tumor;   Ewing's Sarcoma
Intervention: Drug: Recombinant Vaccinia GM-CSF; RAC VAC GM-CSF (JX-594)
15 Recruiting Efficacy and Tolerance of Potassium Hydroxide (10% and 15%) in Molluscum Contagiosum
Condition: Molluscum Contagiosum
Interventions: Drug: Hydroxide Potassium;   Drug: Placebo
16 Recruiting A Phase 3 Efficacy Study of a Recombinant Vaccinia Virus Vaccine to Treat Metastatic Prostate Cancer
Condition: Prostate Cancer Metastatic
Interventions: Biological: PROSTVAC-V/F-TRICOM + GM-CSF;   Biological: PROSTVAC-V/F-TRICOM + GM-CSF placebo;   Biological: Placebo

† Indicates status has not been verified in more than two years
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