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Found 46 studies with search of: Lipase
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Rank Status Study
1 Terminated Dose-ranging Study to Evaluate Efficacy of SLV339 in Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis
Condition: Pancreatic Exocrine Insufficiency Due to Chronic Pancreatitis
Interventions: Drug: Placebo;   Drug: Recombinant Microbial Lipase SLV339
2 Not yet recruiting Children With Lysosomal Acid Lipase Deficiency Who Previously Received Treatment With SBC-102
Conditions: Lysosomal Acid Lipase Deficiency;   Wolman Disease
Intervention: Drug: SBC-102
3 Recruiting Trial in Children With Growth Failure Due to Early Onset Lysosomal Acid Lipase (LAL) Deficiency/Wolman Disease
Conditions: Lysosomal Acid Lipase Deficiency;   Wolman Disease
Intervention: Drug: SBC-102
4 Active, not recruiting Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X]
Condition: Familial Lipoprotein Lipase Deficiency
Interventions: Genetic: Alipogene Tiparvovec (AMT-011), Human LPL [S447X];   Drug: Mycophenolate mofetil;   Drug: cyclosporine
5 Recruiting Enzyme Suppletion in Exocrine Pancreatic Dysfunction
Conditions: Chronic Pancreatitis;   Exocrine Pancreatic Insufficiency
Intervention: Drug: Panzytrat 25.000 FIP-E units of Lipase
6 Recruiting An Observational Study of Patients With Lysosomal Acid Lipase Deficiency/Cholesteryl Ester Storage Disease Phenotype
Conditions: Cholesterol Ester Storage Disease(CESD);   Lysosomal Acid Lipase Deficiency
Intervention:
7 Completed Safety, Tolerability and Pharmacokinetics of SBC-102 in Adult Patients With Lysosomal Acid Lipase Deficiency
Conditions: Cholesterol Ester Storage Disease(CESD);   Lysosomal Acid Lipase Deficiency
Intervention: Drug: SBC-102
8 Enrolling by invitation Extension Study to Evaluate the Long-Term Safety, Tolerability, and Efficacy of SBC-102 in Adult Subjects With Lysosomal Acid Lipase Deficiency
Conditions: Cholesterol Ester Storage Disease(CESD);   Lysosomal Acid Lipase Deficiency
Intervention: Drug: SBC-102
9 Recruiting Lipoprotein Lipase Expression in Chronic Lymphocytic Leukemia
Condition: Chronic Lymphocytic Leukemia
Intervention:
10 Recruiting A Retrospective Natural History Study of Patients With Lysosomal Acid Lipase Deficiency/Wolman Phenotype
Conditions: Lysosomal Acid Lipase Deficiency;   Wolman Disease
Intervention:
11 Completed Efficacy and Safety of Human Lipoprotein Lipase (LPL)[S447X] Expressed by an Adeno-Associated Viral Vector in LPL-deficient Subjects
Condition: Familial Lipoprotein Lipase Deficiency
Interventions: Genetic: Alipogene Tiparvovec (AMT-011), Human LPL [S447X];   Drug: mycophenolate mofetil;   Drug: cyclosporine;   Drug: methylprednisolone
12 Not yet recruiting Effect of Dietary Components on Gastrointestinal Side Effects Induced by Orlistat, a Lipase Inhibitor
Condition: Obesity
Interventions: Dietary Supplement: Control;   Dietary Supplement: Capolac;   Dietary Supplement: Flax fiber;   Dietary Supplement: Capolac+Flax fiber
13 Recruiting Comparison of rhBSSL With Placebo When Added to Infant Formula or Pasteurized Breast Milk During 4 Weeks of Treatment in Preterm Infants
Condition: Prevention of Growth Restriction
Intervention: Drug: rhBSSL (recombinant human bile-salt-stimulated lipase)
14 Completed A Study of the Enzyme Activity and Safety of Pancrelipase in Patients With Severe Exocrine Pancreatic Insufficiency (EPI)
Conditions: Exocrine Pancreatic Insufficiency;   Pancreatitis, Chronic;   Steatorrhea;   Pancreatitis
Interventions: Dietary Supplement: Ensure Plus;   Drug: Pancrelipase in combination with Ensure Plus
15 Completed Randomized Double-Blind Placebo Crossover Study to Evaluate Safety/Efficacy of Two Doses in CP Patients With EPI
Conditions: Chronic Pancreatitis;   Exocrine Pancreatic Insufficiency
Interventions: Drug: Placebo;   Drug: EUR-1008 high dose;   Drug: EUR-1008 low dose
16 Completed Study of Fat Malabsorption by Lipiblock Versus Xenical
Condition: Obesity
Intervention: Drug: Orlistat
17 Completed Study of Pancreatic Enzyme Product in Pediatric Patients With Cystic Fibrosis and Exocrine Pancreatic Insufficiency
Conditions: Cystic Fibrosis;   Exocrine Pancreatic Insufficiency
Intervention: Drug: EUR-1008, ZENPEP
18 Completed Growth Factor/Insulin-like Growth Factor (GH/IGF)-1 Axis in Obese Subjects in Treatment With Orlistat
Condition: Obesity
Interventions: Drug: Orlistat;   Other: normo-caloric diet
19 Recruiting The Influence Of GIP (Glucose-Dependent Insulinotropic Polypeptide) Infusion On Human Adipose Tissue: An In Vivo Study
Condition: Adipose Tissue
Intervention: Other: GIP (glucose dependent insulinotropic peptide) infusion
20 Withdrawn Open Label Safety Study of DCI-1020 in Pediatric Cystic Fibrosis (CF) Patients
Conditions: Digestive System Diseases;   Pancreatic Disease;   Cystic Fibrosis;   Exocrine Pancreatic Insufficiency
Intervention: Drug: DCI 1020

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