Trial record 3 of 4 for:    Miriam Mintzer

Cognitive Stimulation in Adolescents

This study is currently recruiting participants. (see Contacts and Locations)
Verified November 2013 by Johns Hopkins University
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Miriam Mintzer, Johns Hopkins University
ClinicalTrials.gov Identifier:
NCT01948674
First received: September 17, 2013
Last updated: November 21, 2013
Last verified: November 2013
  Purpose

The purpose of this study is to see if computer tasks that challenge the brain (cognitively stimulating tasks) can improve memory and other types of thinking in adolescents and young adults who are being treated for substance use problems. The study will compare the effects of different versions of the computer tasks.


Condition Intervention Phase
Substance Use Disorders
Behavioral: Computerized tasks
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Factorial Assignment
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Cognitive Training in Adolescents During Treatment for Substance Use Disorders

Resource links provided by NLM:


Further study details as provided by Johns Hopkins University:

Primary Outcome Measures:
  • working memory (change from baseline) [ Time Frame: expected within 2 weeks after intervention ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • timeline follow back (change from baseline) [ Time Frame: expected within 2 weeks after intervention ] [ Designated as safety issue: No ]
  • delay discounting (change from baseline) [ Time Frame: expected within 2 weeks after intervention ] [ Designated as safety issue: No ]
  • Stroop (change from baseline) [ Time Frame: expected within 2 weeks after intervention ] [ Designated as safety issue: No ]
  • reading comprehension (change from baseline) [ Time Frame: expected within 2 weeks after intervention ] [ Designated as safety issue: No ]
  • emotion regulation (change from baseline) [ Time Frame: expected within 2 weeks after intervention ] [ Designated as safety issue: No ]
  • Go-No Go (change from baseline) [ Time Frame: expected within 2 weeks after intervention ] [ Designated as safety issue: No ]
  • Global Appraisal of Individual Needs (change from baseline) [ Time Frame: expected within 2 weeks after intervention ] [ Designated as safety issue: No ]

Estimated Enrollment: 90
Study Start Date: October 2013
Estimated Primary Completion Date: July 2016 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: computerized tasks- adaptive Behavioral: Computerized tasks
The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks.
Active Comparator: computerized tasks - nonadaptive Behavioral: Computerized tasks
The study will compare the effects of different methods of computerized mental stimulation. The intervention involves 25 sessions involving computerized cognitive tasks.

  Eligibility

Ages Eligible for Study:   14 Years to 21 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • age 14-21
  • Diagnosis of substance use disorder (SUD) by DSM-IV criteria with marijuana as primary substance of abuse
  • eligible for intensive outpatient treatment

Exclusion Criteria:

  • Untreated psychiatric disorder that might make participation hazardous
  • Any condition associated with severe cognitive impairment
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01948674

Contacts
Contact: Cara DiClemente, BA 410 550-1683 cdiclem3@jhmi.edu

Locations
United States, Maryland
Mountain Manor Treatment Center Recruiting
Baltimore, Maryland, United States, 21229
Sponsors and Collaborators
Johns Hopkins University
Investigators
Principal Investigator: Miriam Z Mintzer, PhD Johns Hopkins University
  More Information

No publications provided

Responsible Party: Miriam Mintzer, Associate Professor, Johns Hopkins University
ClinicalTrials.gov Identifier: NCT01948674     History of Changes
Other Study ID Numbers: NA_00080023, R21DA034942
Study First Received: September 17, 2013
Last Updated: November 21, 2013
Health Authority: United States: Federal Government
United States: Institutional Review Board

Additional relevant MeSH terms:
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders

ClinicalTrials.gov processed this record on August 26, 2014