Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) Metabolism During Acute Hyperglycemia

This study is ongoing, but not recruiting participants.

Sponsor:

Information provided by (Responsible Party):

University of Aarhus

ClinicalTrials.gov Identifier:

NCT01178957

First received: April 21, 2010

Last updated: November 1, 2012

Last verified: November 2012

History of Changes

Purpose

The purpose of this study is to estimate the acute effect of hyperglycemia on Very-Low-Density-Lipoprotein-triglyceride(VLDL-TG) secretion.

Condition	Intervention
Type 1 Diabetes	Other: Hyperglycemia

Study Type:	Observational
Study Design:	Observational Model: Cohort Time Perspective: Prospective
Official Title:	Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) Metabolism During Acute Hyperglycemia

Resource links provided by NLM:

Genetics Home Reference related topics: type 1 diabetes

MedlinePlus related topics: Diabetes Diabetes Type 1 Hyperglycemia

U.S. FDA Resources

Further study details as provided by University of Aarhus:

Primary Outcome Measures:

Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) secretion [ Time Frame: 8 hours ] [ Designated as safety issue: No ]
Very-Low-Density-Lipoprotein-Triglyceride(VLDL-TG) kinetics over a single study day

Biospecimen Retention: Samples With DNA

Blood Samples

Estimated Enrollment:	8
Study Start Date:	April 2012
Estimated Study Completion Date:	April 2013
Estimated Primary Completion Date:	April 2013 (Final data collection date for primary outcome measure)

Groups/Cohorts	Assigned Interventions
Type 1 diabetes	Other: Hyperglycemia Hyperglycemia with a blood glucose of 15 mmol/L

Eligibility

Ages Eligible for Study:	18 Years to 50 Years
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Type 1 diabetics

Criteria

Inclusion Criteria:

Type 1 diabetes
Age 18-50 years

Exclusion Criteria:

Smoking
Alcohol abuse
Use of medications (except insulin in diabetics)

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT01178957

Locations

Denmark
Department of Endocrinology MEA, Aarhus Hospital
Aarhus C, Denmark, 8000

Sponsors and Collaborators

University of Aarhus

More Information

No publications provided

Responsible Party:	University of Aarhus
ClinicalTrials.gov Identifier:	NCT01178957 History of Changes
Other Study ID Numbers:	ES-0004
Study First Received:	April 21, 2010
Last Updated:	November 1, 2012
Health Authority:	Denmark: Danish Dataprotection Agency

Keywords provided by University of Aarhus:

Type 1 diabetes
Very-Low-Density-Lipoprotein(VLDL)
Hyperglycemia

Additional relevant MeSH terms:

Diabetes Mellitus
Diabetes Mellitus, Type 1
Hyperglycemia
Glucose Metabolism Disorders

Metabolic Diseases
Endocrine System Diseases
Autoimmune Diseases
Immune System Diseases

ClinicalTrials.gov processed this record on May 23, 2013

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