Radiation Therapy With or Without Chemotherapy in Patients With Stage I or Stage II Cervical Cancer Who Previously Underwent Surgery

This study is currently recruiting participants.
Verified March 2014 by Gynecologic Oncology Group
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Gynecologic Oncology Group
ClinicalTrials.gov Identifier:
NCT01101451
First received: April 9, 2010
Last updated: March 7, 2014
Last verified: March 2014
  Purpose

This randomized phase III trial is studying giving radiation therapy together with chemotherapy to see how well it works compared to radiation therapy alone in treating patients with stage I or stage II cervical cancer who previously underwent surgery. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving radiation therapy together with chemotherapy is more effective than radiation therapy alone in treating patients with cervical cancer.


Condition Intervention Phase
Cervical Adenocarcinoma
Cervical Adenosquamous Cell Carcinoma
Cervical Squamous Cell Carcinoma
Stage IA Cervical Cancer
Stage IB Cervical Cancer
Stage IIA Cervical Cancer
Radiation: external beam radiation therapy
Radiation: intensity-modulated radiation therapy
Drug: cisplatin
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Randomized Phase III Clinical Trial of Adjuvant Radiation Versus Chemoradiation in Intermediate Risk, Stage I/IIA Cervical Cancer Treated With Initial Radical Hysterectomy and Pelvic Lymphadenectomy

Resource links provided by NLM:


Further study details as provided by Gynecologic Oncology Group:

Primary Outcome Measures:
  • Recurrence-free survival [ Time Frame: From protocol registration to date of first documented recurrence, death or date of last contact, assessed up to 5 years ] [ Designated as safety issue: No ]
    Estimated according to the method of Kaplan and Meier and compared using the one sided log-rank test.


Secondary Outcome Measures:
  • Overall survival [ Time Frame: From entry into the study to death; or for living patients, the date of last contact regardless of whether or not this contact is on a subsequent protocol, assessed up to 5 years ] [ Designated as safety issue: No ]
    Estimated according to the method of Kaplan and Meier and compared using the one sided log-rank test.

  • Local control [ Time Frame: Up to 5 years ] [ Designated as safety issue: No ]
    Assessed with Exact Logistic Regression adjusted known prognostic factors.

  • Adverse events graded according to the active version of CTCAE [ Time Frame: Up to 5 years ] [ Designated as safety issue: Yes ]
    Compared between arms using Fishers' exact test.

  • Quality of life, assessed using the FACT-C, neuro-toxicity questions, additional toxicity questions, and pain questions [ Time Frame: Up to 36 weeks ] [ Designated as safety issue: No ]

Estimated Enrollment: 480
Study Start Date: April 2010
Estimated Primary Completion Date: December 2020 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Arm I (EBRT, IMRT)
Patients undergo pelvic EBRT or IMRT once daily, 5 days a week, for 5½ weeks.
Radiation: external beam radiation therapy
Undergo radiotherapy
Other Name: EBRT
Radiation: intensity-modulated radiation therapy
Undergo radiotherapy
Other Name: IMRT
Experimental: Arm II (cisplatin, EBRT, IMRT)
Patients receive cisplatin IV over 1-2 hours on day 1 and undergo radiotherapy as in arm I. Treatment with cisplatin repeats every 7 days for up to 6 weeks in the absence of disease progression or unacceptable toxicity.
Radiation: external beam radiation therapy
Undergo radiotherapy
Other Name: EBRT
Radiation: intensity-modulated radiation therapy
Undergo radiotherapy
Other Name: IMRT
Drug: cisplatin
Given IV
Other Names:
  • CACP
  • CDDP
  • CPDD
  • DDP

Detailed Description:

PRIMARY OBJECTIVES:

I. To determine if post-operative adjuvant chemoradiotherapy (CRT) can significantly improve recurrence-free survival (RFS) when compared to radiation therapy (RT) alone in patients with intermediate-risk factors stage I-IIA cervical cancer after treatment with radical hysterectomy.

SECONDARY OBJECTIVES:

I. To compare the overall survival (OS) of patients treated with these regimens.

II. To assess differences in incidence and severity of regimen-attributed adverse events in these patients.

III. To provide assessment of patient risk vs benefit (positive study only). IV. To determine whether post-operative adjuvant CRT improves the health-related quality-of-life compared to RT alone.

V. To compare toxicity profiles with particular focus on treatment-related genitourinary, gastrointestinal, neurological, pain, and sexual adverse events in these patients.

TERTIARY OBJECTIVES:

I. To bank archival tumor tissue for research studies, including studies that evaluate the association between biomarkers, RFS, OS, and clinical-surgical-pathologic characteristics in patients treated with these regimens.

II. To bank DNA from whole blood for research studies, including studies that evaluate associations between single nucleotide polymorphisms (SNPs), and measures of clinical outcome, including RFS, OS, and adverse events in patients treated with these regimens.

OUTLINE: This is a multicenter study. Patients are stratified according to capillary-lymphovascular space involvement (positive vs negative), stromal invasion (deep vs middle vs superficial), radiotherapy modality (external-beam radiation therapy [EBRT] vs intensity-modulated radiation therapy [IMRT]), and cooperative group (KGOG vs GOG). Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients undergo pelvic EBRT or IMRT 5 days a week for 5.5 weeks.

ARM II: Patients receive cisplatin IV over 1-2 hours on day 1 and undergo radiotherapy as in arm I. Treatment with cisplatin repeats every 7 days for up to 6 weeks in the absence of disease progression or unacceptable toxicity.

Patients complete questionnaires on smoking history, Functional Assessment of Cancer Therapy (FACT-G, Version 4), FACT-Neurotoxicity subscale, and the Brief Pain Inventory (BPI) at baseline and periodically during study.

Tumor tissue and blood samples may be collected and banked for future biomarker and other analysis.

After completion of study therapy, patients are followed up every 3 months for 2 years, and then every 6 months for 3 years.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Pathologically confirmed primary cervical cancer comprising one of the following cell types:

    • Squamous cell carcinoma
    • Adenosquamous carcinoma
    • Adenocarcinoma
  • Stage I-IIA disease
  • Initially treated with a standard radical hysterectomy with pelvic lymphadenectomy
  • Patients with depth of stromal invasion and lymphovascular space involvement to be pathologically confirmed must meet the following criteria:

    • Positive capillary-lymphovascular space involvement and one of the following:

      • Deep third penetration
      • Middle third penetration, clinical tumor ≥ 2 cm
      • Superficial third penetration, clinical tumor ≥ 5 cm
    • Negative capillary-lymphatic space involvement

      • Middle or deep third penetration, clinical tumor ≥ 4 cm
  • No patients with tumor in the parametria, pelvic lymph nodes, or any other extra-uterine site or with positive surgical margins
  • GOG performance status 0-2
  • ANC ≥ 1,500/mm³
  • Platelet count ≥ 100,000/mm³
  • Creatinine normal OR creatinine clearance ≥ 60 mL/min
  • Bilirubin ≤ 1.5 times upper limit of normal (ULN)
  • Alkaline phosphate ≤ 3 times ULN
  • SGOT ≤ 3 times ULN
  • No septicemia or severe infection
  • No intestinal obstruction or gastrointestinal bleeding
  • No post-operative fistula
  • No circumstances that do not permit completion of the study or the required study follow-up
  • No renal abnormalities requiring modification of radiation field (e.g., pelvic kidney or renal transplant)
  • No prior malignancy within the past 5 years except nonmelanoma skin cancer
  • No concurrent brachytherapy boost
  • At least 3 weeks but ≤ 8 weeks since surgery
  • No prior radiotherapy or chemotherapy for cancer of the cervix
  • No prior cancer treatment that contraindicates this protocol therapy
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01101451

  Hide Study Locations
Locations
United States, Arizona
Saint Joseph's Hospital and Medical Center Recruiting
Phoenix, Arizona, United States, 85013
Contact: John H. Farley    877-602-4111      
Principal Investigator: John H. Farley         
United States, California
Roy and Patricia Disney Family Cancer Center Withdrawn
Burbank, California, United States, 91505
Providence Saint Joseph Medical Center/Disney Family Cancer Center Recruiting
Burbank, California, United States, 91505
Contact: Richard L. Friedman    818-847-3220      
Principal Investigator: Richard L. Friedman         
John Muir Medical Center-Concord Campus Recruiting
Concord, California, United States, 94520
Contact: Babak Edraki    925-674-2580      
Principal Investigator: Babak Edraki         
Los Angeles County-USC Medical Center Withdrawn
Los Angeles, California, United States, 90033
Cedars-Sinai Medical Center Recruiting
Los Angeles, California, United States, 90048
Contact: Bobbie J. Rimel    310-423-8965    info@ccadmin.wustl.edu   
Principal Investigator: Bobbie J. Rimel         
University of Southern California Withdrawn
Los Angeles, California, United States, 90033
Memorial Medical Center Recruiting
Modesto, California, United States, 95355
Contact: Jorge A. Garcia-Young    209-572-7116      
Principal Investigator: Jorge A. Garcia-Young         
Palo Alto Medical Foundation-Gynecologic Oncology Recruiting
Mountain View, California, United States, 94040
Contact: Albert L. Pisani    650-934-7000      
Principal Investigator: Albert L. Pisani         
Pomona Valley Hospital Medical Center Recruiting
Pomona, California, United States, 91767
Contact: Alberto A. Mendivil    949-642-5165      
Principal Investigator: Alberto A. Mendivil         
Olive View-University of California Los Angeles Medical Center Recruiting
Sylmar, California, United States, 91342
Contact: Christine H. Holschneider    888-798-0719      
Principal Investigator: Christine H. Holschneider         
John Muir Medical Center Recruiting
Walnut Creek, California, United States, 94598
Contact: Babak Edraki    925-674-2580      
Principal Investigator: Babak Edraki         
United States, Colorado
The Medical Center of Aurora Recruiting
Aurora, Colorado, United States, 80012
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Boulder Community Hospital Recruiting
Boulder, Colorado, United States, 80301
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Penrose-Saint Francis Healthcare Recruiting
Colorado Springs, Colorado, United States, 80907
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Porter Adventist Hospital Recruiting
Denver, Colorado, United States, 80210
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Colorado Cancer Research Program CCOP Recruiting
Denver, Colorado, United States, 80224-2522
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Exempla Saint Joseph Hospital Recruiting
Denver, Colorado, United States, 80218
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Rose Medical Center Recruiting
Denver, Colorado, United States, 80220
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Presbyterian - Saint Lukes Medical Center - Health One Recruiting
Denver, Colorado, United States, 80218
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Swedish Medical Center Recruiting
Englewood, Colorado, United States, 80113
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
North Colorado Medical Center Recruiting
Greeley, Colorado, United States, 80631
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Saint Anthony Hospital Recruiting
Lakewood, Colorado, United States, 80228
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Littleton Adventist Hospital Recruiting
Littleton, Colorado, United States, 80122
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Sky Ridge Medical Center Recruiting
Lone Tree, Colorado, United States, 80124
Contact: Eduardo R. Pajon    888-336-8262      
Principal Investigator: Eduardo R. Pajon         
Longmont United Hospital Recruiting
Longmont, Colorado, United States, 80501
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
McKee Medical Center Recruiting
Loveland, Colorado, United States, 80539
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Parker Adventist Hospital Recruiting
Parker, Colorado, United States, 80138
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Saint Mary Corwin Medical Center Recruiting
Pueblo, Colorado, United States, 81004
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
Exempla Lutheran Medical Center Recruiting
Wheat Ridge, Colorado, United States, 80033
Contact: Keren Sturtz    888-785-6789      
Principal Investigator: Keren Sturtz         
United States, Connecticut
Saint Francis Hospital and Medical Center Recruiting
Hartford, Connecticut, United States, 06105
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Hartford Hospital Recruiting
Hartford, Connecticut, United States, 06102
Contact: James S. Hoffman    860-224-5660      
Principal Investigator: James S. Hoffman         
The Hospital of Central Connecticut Recruiting
New Britain, Connecticut, United States, 06050
Contact: James S. Hoffman    860-224-5660      
Principal Investigator: James S. Hoffman         
United States, District of Columbia
Sibley Memorial Hospital Recruiting
Washington, District of Columbia, United States, 20016
Contact: Mildred R. Chernofsky    202-243-2373      
Principal Investigator: Mildred R. Chernofsky         
United States, Florida
University of Miami Miller School of Medicine-Sylvester Cancer Center Recruiting
Miami, Florida, United States, 33136
Contact: Joseph A. Lucci    866-574-5124    Sylvester@emergingmed.com   
Principal Investigator: Joseph A. Lucci         
Florida Hospital Recruiting
Orlando, Florida, United States, 32803
Contact: James E. Kendrick    407-303-5623      
Principal Investigator: James E. Kendrick         
United States, Georgia
Piedmont Hospital Recruiting
Atlanta, Georgia, United States, 30309
Contact: Adam W. Nowlan    404-425-7943    phri@piedmont.org   
Principal Investigator: Adam W. Nowlan         
Emory University/Winship Cancer Institute Recruiting
Atlanta, Georgia, United States, 30322
Contact: Namita Khanna    404-778-1868      
Principal Investigator: Namita Khanna         
Northside Hospital Recruiting
Atlanta, Georgia, United States, 30342
Contact: Guilherme Henrique C. Cantuaria    404-303-3355    clinicaltrials@northside.com   
Principal Investigator: Guilherme Henrique C. Cantuaria         
Saint Joseph's Hospital of Atlanta Recruiting
Atlanta, Georgia, United States, 30342
Contact: Thomas E. Seay    404-303-3355      
Principal Investigator: Thomas E. Seay         
John B Amos Cancer Center Recruiting
Columbus, Georgia, United States, 31904
Contact: Gregory P. Sfakianos    706-660-6404      
Principal Investigator: Gregory P. Sfakianos         
Dekalb Medical Center Recruiting
Decatur, Georgia, United States, 30033
Contact: Thomas E. Seay    404-303-3355      
Principal Investigator: Thomas E. Seay         
Northeast Georgia Medical Center Recruiting
Gainesville, Georgia, United States, 30501
Contact: Andrew E. Green    770-219-8800    cancerpatient.navigator@nghs.com   
Principal Investigator: Andrew E. Green         
Wellstar Kennestone Hospital Recruiting
Marietta, Georgia, United States, 30060
Contact: Thomas E. Seay    404-303-3355      
Principal Investigator: Thomas E. Seay         
Southern Regional Medical Center Recruiting
Riverdale, Georgia, United States, 30274
Contact: Thomas E. Seay    404-303-3355      
Principal Investigator: Thomas E. Seay         
Memorial Health University Medical Center Recruiting
Savannah, Georgia, United States, 31403
Contact: James J. Burke    912-350-8568      
Principal Investigator: James J. Burke         
Saint Joseph's-Candler Health System Recruiting
Savannah, Georgia, United States, 31405
Contact: William E. Richards    800-622-6877    uchealthnews@uc.edu   
Principal Investigator: William E. Richards         
United States, Hawaii
Hawaii Minority Based CCOP Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Michael E. Carney    808-983-6090      
Principal Investigator: Michael E. Carney         
Queen's Medical Center Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Michael E. Carney    808-983-6090      
Principal Investigator: Michael E. Carney         
University of Hawaii Recruiting
Honolulu, Hawaii, United States, 96813
Contact: Michael E. Carney    808-983-6090      
Principal Investigator: Michael E. Carney         
United States, Idaho
Saint Alphonsus Regional Medical Center Recruiting
Boise, Idaho, United States, 83706
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
United States, Illinois
Saint Anthony's Health Terminated
Alton, Illinois, United States, 62002
University of Illinois Recruiting
Chicago, Illinois, United States, 60612
Contact: Rajul Kothari    312-355-3046      
Principal Investigator: Rajul Kothari         
Sudarshan K Sharma MD Limted-Gynecologic Oncology Active, not recruiting
Hinsdale, Illinois, United States, 60521
Loyola University Medical Center Recruiting
Maywood, Illinois, United States, 60153
Contact: Ronald K. Potkul    708-226-4357      
Principal Investigator: Ronald K. Potkul         
Good Samaritan Regional Health Center Recruiting
Mount Vernon, Illinois, United States, 62864
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
United States, Indiana
Radiation Oncology Associates PC Recruiting
Fort Wayne, Indiana, United States, 46804
Contact: Brian K. Chang    260-373-8888    parkviewresearch@parkview.com   
Principal Investigator: Brian K. Chang         
Parkview Hospital Recruiting
Fort Wayne, Indiana, United States, 46805
Contact: Brian K. Chang    260-373-8888    parkviewresearch@parkview.com   
Principal Investigator: Brian K. Chang         
Indiana University Medical Center Recruiting
Indianapolis, Indiana, United States, 46202
Contact: Jeanne M. Schilder    317-274-2552      
Principal Investigator: Jeanne M. Schilder         
Saint Vincent Oncology Center Terminated
Indianapolis, Indiana, United States, 46260
United States, Iowa
McFarland Clinic PC-William R Bliss Cancer Center Recruiting
Ames, Iowa, United States, 50010
Contact: Joseph J. Merchant    515-239-2621      
Principal Investigator: Joseph J. Merchant         
Medical Oncology and Hematology Associates-West Des Moines Recruiting
Clive, Iowa, United States, 50325
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Mercy Cancer Center-West Lakes Recruiting
Clive, Iowa, United States, 50325
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Iowa Oncology Research Association CCOP Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Iowa Lutheran Hospital Recruiting
Des Moines, Iowa, United States, 50316
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Medical Oncology and Hematology Associates-Laurel Recruiting
Des Moines, Iowa, United States, 50314
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Iowa Methodist Medical Center Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Medical Oncology and Hematology Associates-Des Moines Recruiting
Des Moines, Iowa, United States, 50309
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Mercy Medical Center - Des Moines Recruiting
Des Moines, Iowa, United States, 50314
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
University of Iowa Hospitals and Clinics Recruiting
Iowa City, Iowa, United States, 52242
Contact: David P. Bender    800-237-1225      
Principal Investigator: David P. Bender         
Mercy Medical Center-Sioux City Active, not recruiting
Sioux City, Iowa, United States, 51104
Saint Luke's Regional Medical Center Active, not recruiting
Sioux City, Iowa, United States, 51104
Siouxland Hematology Oncology Associates Active, not recruiting
Sioux City, Iowa, United States, 51101
Mercy Medical Center-West Lakes Recruiting
West Des Moines, Iowa, United States, 50266
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
Methodist West Hospital Recruiting
West Des Moines, Iowa, United States, 50266-7700
Contact: Robert J. Behrens    888-244-6061    sherrijr@iora.org   
Principal Investigator: Robert J. Behrens         
United States, Kansas
University of Kansas Medical Center Active, not recruiting
Kansas City, Kansas, United States, 66160
United States, Kentucky
University of Kentucky Recruiting
Lexington, Kentucky, United States, 40536
Contact: Frederick R. Ueland    859-257-3379      
Principal Investigator: Frederick R. Ueland         
Pikeville Medical Center Active, not recruiting
Pikeville, Kentucky, United States, 41501
United States, Louisiana
Mary Bird Perkins Cancer Center Recruiting
Baton Rouge, Louisiana, United States, 70809
Contact: Robert W. Veith    504-568-3410    aconne1@lsuhsc.edu   
Principal Investigator: Robert W. Veith         
Woman's Hospital Recruiting
Baton Rouge, Louisiana, United States, 70817
Contact: Giles Fort    225-215-1353    clinicalreserach@marybird.com   
Principal Investigator: Giles Fort         
Louisiana State University Health Science Center Recruiting
New Orleans, Louisiana, United States, 70112
Contact: Robert W. Veith    504-568-3410    aconne1@lsuhsc.edu   
Principal Investigator: Robert W. Veith         
United States, Maine
Maine Medical Center-Bramhall Campus Recruiting
Portland, Maine, United States, 04102
Contact: Ian J. Bristol    207-396-8090    wrighd@mmc.org   
Principal Investigator: Ian J. Bristol         
Maine Medical Center- Scarborough Campus Recruiting
Scarborough, Maine, United States, 04074
Contact: Ian J. Bristol    207-396-8090    wrighd@mmc.org   
Principal Investigator: Ian J. Bristol         
United States, Maryland
Greater Baltimore Medical Center Recruiting
Baltimore, Maryland, United States, 21204
Contact: Paul Celano    443-849-3706      
Principal Investigator: Paul Celano         
Walter Reed National Military Medical Center Recruiting
Bethesda, Maryland, United States, 20889-5600
Contact: Michael P. Stany    301-319-2100      
Principal Investigator: Michael P. Stany         
Holy Cross Hospital Recruiting
Silver Spring, Maryland, United States, 20910
Contact: Sheela D. Modin    310-754-7552      
Principal Investigator: Sheela D. Modin         
United States, Michigan
Saint Joseph Mercy Hospital Recruiting
Ann Arbor, Michigan, United States, 48106-0995
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Michigan Cancer Research Consortium Community Clinical Oncology Program Recruiting
Ann Arbor, Michigan, United States, 48106
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Oakwood Hospital Recruiting
Dearborn, Michigan, United States, 48124
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Saint John Hospital and Medical Center Recruiting
Detroit, Michigan, United States, 48236
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Wayne State University-Karmanos Cancer Institute Recruiting
Detroit, Michigan, United States, 48201
Contact: Robert T. Morris    313-576-9363      
Principal Investigator: Robert T. Morris         
Genesys Hurley Cancer Institute Recruiting
Flint, Michigan, United States, 48503
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Hurley Medical Center Recruiting
Flint, Michigan, United States, 48502
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Genesys Regional Medical Center Terminated
Grand Blanc, Michigan, United States, 48439
Allegiance Health Recruiting
Jackson, Michigan, United States, 49201
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Borgess Medical Center Recruiting
Kalamazoo, Michigan, United States, 49001
Contact: Raymond S. Lord    269-373-7458      
Principal Investigator: Raymond S. Lord         
Bronson Methodist Hospital Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Raymond S. Lord    269-373-7458      
Principal Investigator: Raymond S. Lord         
West Michigan Cancer Center Recruiting
Kalamazoo, Michigan, United States, 49007
Contact: Raymond S. Lord    269-373-7458      
Principal Investigator: Raymond S. Lord         
Sparrow Hospital Recruiting
Lansing, Michigan, United States, 48912
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Saint Mary Mercy Hospital Recruiting
Livonia, Michigan, United States, 48154
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Saint Joseph Mercy Oakland Recruiting
Pontiac, Michigan, United States, 48341-2985
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Saint Joseph Mercy Port Huron Recruiting
Port Huron, Michigan, United States, 48060
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Saint Mary's of Michigan Recruiting
Saginaw, Michigan, United States, 48601
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
Providence Hospital Recruiting
Southfield, Michigan, United States, 48075
Contact: Vinay K. Malviya    248-849-5337    jaswinder.grewal@stjohn.org   
Principal Investigator: Vinay K. Malviya         
Saint John Macomb-Oakland Hospital Recruiting
Warren, Michigan, United States, 48093
Contact: Philip J. Stella    734-712-3456      
Principal Investigator: Philip J. Stella         
United States, Minnesota
Fairview Ridges Hospital Recruiting
Burnsville, Minnesota, United States, 55337
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Mercy Hospital Recruiting
Coon Rapids, Minnesota, United States, 55433
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Fairview-Southdale Hospital Recruiting
Edina, Minnesota, United States, 55435
Contact: Patrick J. Flynn    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Patrick J. Flynn         
Unity Hospital Recruiting
Fridley, Minnesota, United States, 55432
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Hutchinson Area Health Care Recruiting
Hutchinson, Minnesota, United States, 55350
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Minnesota Oncology Hematology PA-Maplewood Recruiting
Maplewood, Minnesota, United States, 55109
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Saint John's Hospital - Healtheast Recruiting
Maplewood, Minnesota, United States, 55109
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Hennepin County Medical Center Recruiting
Minneapolis, Minnesota, United States, 55415
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Abbott-Northwestern Hospital Recruiting
Minneapolis, Minnesota, United States, 55407
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
New Ulm Medical Center Recruiting
New Ulm, Minnesota, United States, 56073
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
North Memorial Medical Health Center Recruiting
Robbinsdale, Minnesota, United States, 55422
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Mayo Clinic Recruiting
Rochester, Minnesota, United States, 55905
Contact: Harry J. Long    507-538-7623      
Principal Investigator: Harry J. Long         
Metro-Minnesota CCOP Recruiting
Saint Louis Park, Minnesota, United States, 55416
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Park Nicollet Clinic - Saint Louis Park Recruiting
Saint Louis Park, Minnesota, United States, 55416
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Regions Hospital Recruiting
Saint Paul, Minnesota, United States, 55101
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
United Hospital Recruiting
Saint Paul, Minnesota, United States, 55102
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Saint Francis Regional Medical Center Recruiting
Shakopee, Minnesota, United States, 55379
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Lakeview Hospital Recruiting
Stillwater, Minnesota, United States, 55082
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Ridgeview Medical Center Recruiting
Waconia, Minnesota, United States, 55387
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Rice Memorial Hospital Recruiting
Willmar, Minnesota, United States, 56201
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Minnesota Oncology and Hematology PA-Woodbury Recruiting
Woodbury, Minnesota, United States, 55125
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
United States, Mississippi
University of Mississippi Medical Center Recruiting
Jackson, Mississippi, United States, 39216
Contact: James T. Thigpen    601-815-6700      
Principal Investigator: James T. Thigpen         
Singing River Hospital Recruiting
Pascagoula, Mississippi, United States, 39581
Contact: James E. Clarkson    228-809-5292      
Principal Investigator: James E. Clarkson         
United States, Missouri
Southeast Cancer Center Recruiting
Cape Girardeau, Missouri, United States, 63703
Contact: Alan P. Lyss    800-392-0936      
Principal Investigator: Alan P. Lyss         
Saint Francis Medical Center Recruiting
Cape Girardeau, Missouri, United States, 63703
Contact: Bethany G. Sleckman    913-948-5588      
Principal Investigator: Bethany G. Sleckman         
University of Missouri - Ellis Fischel Recruiting
Columbia, Missouri, United States, 65212
Contact: Mark I. Hunter    573-882-7440      
Principal Investigator: Mark I. Hunter         
Capital Region Medical Center-Goldschmidt Cancer Center Recruiting
Jefferson City, Missouri, United States, 65109
Contact: Alan P. Lyss    800-392-0936      
Principal Investigator: Alan P. Lyss         
Mercy Hospital-Joplin Recruiting
Joplin, Missouri, United States, 64804
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Freeman Health System Recruiting
Joplin, Missouri, United States, 64804
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Phelps County Regional Medical Center Recruiting
Rolla, Missouri, United States, 65401
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Saint John's Clinic-Rolla-Cancer and Hematology Recruiting
Rolla, Missouri, United States, 65401
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Saint John's Mercy Medical Center Recruiting
Saint Louis, Missouri, United States, 63141
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Saint Louis-Cape Girardeau CCOP Terminated
Saint Louis, Missouri, United States, 63141
Missouri Baptist Medical Center Recruiting
Saint Louis, Missouri, United States, 63131
Contact: Alan P. Lyss    800-392-0936      
Principal Investigator: Alan P. Lyss         
Mercy Hospital Springfield Recruiting
Springfield, Missouri, United States, 65804
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
Ozark Health Ventures LLC dba Cancer Research for The Ozarks Springfield Active, not recruiting
Springfield, Missouri, United States, 65802
CoxHealth South Hospital Recruiting
Springfield, Missouri, United States, 65807
Contact: Jay W. Carlson    888-244-6061    sherrijr@iora.org   
Principal Investigator: Jay W. Carlson         
United States, Nebraska
Nebraska Methodist Hospital Recruiting
Omaha, Nebraska, United States, 68114
Contact: Peter C. Morris    402-354-7939    kathryn.bartz@nmhs.org   
Principal Investigator: Peter C. Morris         
United States, Nevada
Women's Cancer Center of Nevada Recruiting
Las Vegas, Nevada, United States, 89169
Contact: Nicola M. Spirtos    702-851-4672      
Principal Investigator: Nicola M. Spirtos         
Center of Hope at Renown Medical Center Recruiting
Reno, Nevada, United States, 89502
Contact: Peter C. Lim    866-513-8227      
Principal Investigator: Peter C. Lim         
Renown Regional Medical Center Recruiting
Reno, Nevada, United States, 89502
Contact: Peter C. Lim    866-513-8227      
Principal Investigator: Peter C. Lim         
United States, New Hampshire
Dartmouth Hitchcock Medical Center Recruiting
Lebanon, New Hampshire, United States, 03756
Contact: Leslie R. DeMars    800-639-6918    cancer.research.nurse@dartmouth.edu   
Principal Investigator: Leslie R. DeMars         
United States, New Jersey
Monmouth Medical Center Recruiting
Long Branch, New Jersey, United States, 07740
Contact: Mitchell F. Weiss    732-923-7689      
Principal Investigator: Mitchell F. Weiss         
Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County Recruiting
Mount Holly, New Jersey, United States, 08060
Contact: Randolph B. Deger    888-847-8823      
Principal Investigator: Randolph B. Deger         
UMDNJ - New Jersey Medical School Recruiting
Newark, New Jersey, United States, 07103
Contact: Bernadette M. Cracchiolo    732-235-8675      
Principal Investigator: Bernadette M. Cracchiolo         
The Women's Institute for Gynecologic Cancer and Special Pelvic Surgery Withdrawn
Phillipsburg, New Jersey, United States, 08865
Valley Hospital Terminated
Ridgewood, New Jersey, United States, 07450
Community Medical Center Recruiting
Toms River, New Jersey, United States, 08755
Contact: David J. D'Ambrosio    732-818-3882      
Principal Investigator: David J. D'Ambrosio         
Inspira Medical Center Vineland Recruiting
Vineland, New Jersey, United States, 08360
Contact: Ramakrishna R. Sudhindra    856-641-7933      
Principal Investigator: Ramakrishna R. Sudhindra         
Virtua West Jersey Hospital Voorhees Recruiting
Voorhees, New Jersey, United States, 08043
Contact: Randolph B. Deger    888-847-8823      
Principal Investigator: Randolph B. Deger         
United States, New Mexico
University of New Mexico Cancer Center Recruiting
Albuquerque, New Mexico, United States, 87106
Contact: Teresa L. Rutledge    505-272-6972      
Principal Investigator: Teresa L. Rutledge         
Southwest Gynecologic Oncology Associates Inc Recruiting
Albuquerque, New Mexico, United States, 87106
Contact: Teresa L. Rutledge    505-272-6972      
Principal Investigator: Teresa L. Rutledge         
Memorial Medical Center - Las Cruces Recruiting
Las Cruces, New Mexico, United States, 88011
Contact: Carolyn Y. Muller    505-272-6972      
Principal Investigator: Carolyn Y. Muller         
United States, New York
Women's Cancer Care Associates LLC Recruiting
Albany, New York, United States, 12208
Contact: Thomas P. Morrissey    518-458-1390      
Principal Investigator: Thomas P. Morrissey         
Montefiore Medical Center-Weiler Division Active, not recruiting
Bronx, New York, United States, 10461
State University of New York Downstate Medical Center Recruiting
Brooklyn, New York, United States, 11203
Contact: Ovadia Abulafia    718-270-8216    sima.terebelo@downstate.edu   
Principal Investigator: Ovadia Abulafia         
Memorial Sloan-Kettering Cancer Center Recruiting
New York, New York, United States, 10065
Contact: Mario M. Leitao    212-639-7202      
Principal Investigator: Mario M. Leitao         
Beth Israel Medical Center Recruiting
New York, New York, United States, 10003
Contact: Manjeet Chadha    212-844-6286      
Principal Investigator: Manjeet Chadha         
Saint Luke's Roosevelt Hospital Center - Saint Luke's Division Recruiting
New York, New York, United States, 10025
Contact: Manjeet Chadha    212-844-6286      
Principal Investigator: Manjeet Chadha         
Stony Brook University Medical Center Recruiting
Stony Brook, New York, United States, 11794
Contact: Michael L. Pearl    800-862-2215      
Principal Investigator: Michael L. Pearl         
United States, North Carolina
Randolph Hospital Active, not recruiting
Asheboro, North Carolina, United States, 27203
University of North Carolina Recruiting
Chapel Hill, North Carolina, United States, 27599
Contact: Linda Van Le    877-668-0683    cancerclinicaltrials@med.unc.edu   
Principal Investigator: Linda Van Le         
Carolinas Medical Center Active, not recruiting
Charlotte, North Carolina, United States, 28203
Wayne Memorial Hospital Recruiting
Goldsboro, North Carolina, United States, 27534
Contact: James N. Atkins    919-580-0000      
Principal Investigator: James N. Atkins         
Cone Health Cancer Center Active, not recruiting
Greensboro, North Carolina, United States, 27403
Annie Penn Memorial Hospital Active, not recruiting
Reidsville, North Carolina, United States, 27320
Wake Forest University Health Sciences Recruiting
Winston-Salem, North Carolina, United States, 27157
Contact: Samuel S. Lentz    336-713-6771      
Principal Investigator: Samuel S. Lentz         
United States, North Dakota
Sanford Bismarck Medical Center Withdrawn
Bismarck, North Dakota, United States, 58501
Mid Dakota Clinic Terminated
Bismarck, North Dakota, United States, 58501
Saint Alexius Medical Center Terminated
Bismarck, North Dakota, United States, 58501
Bismarck Cancer Center Recruiting
Bismarck, North Dakota, United States, 58501
Contact: Edward J. Wos    701-323-5760    tfischer@mohs.org   
Principal Investigator: Edward J. Wos         
United States, Ohio
Summa Akron City Hospital/Cooper Cancer Center Recruiting
Akron, Ohio, United States, 44304
Contact: Vivian E. von Gruenigen    330-375-6101      
Principal Investigator: Vivian E. von Gruenigen         
Akron General Medical Center Withdrawn
Akron, Ohio, United States, 44307
Adena Regional Medical Center Recruiting
Chillicothe, Ohio, United States, 45601
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
University of Cincinnati Recruiting
Cincinnati, Ohio, United States, 45267
Contact: Eric L. Eisenhauer    513-558-4553    uchealthnews@uc.edu   
Principal Investigator: Eric L. Eisenhauer         
Cleveland Clinic Cancer Center/Fairview Hospital Recruiting
Cleveland, Ohio, United States, 44111
Contact: Peter G. Rose    866-223-8100      
Principal Investigator: Peter G. Rose         
Cleveland Clinic Foundation Recruiting
Cleveland, Ohio, United States, 44195
Contact: Peter G. Rose    866-223-8100      
Principal Investigator: Peter G. Rose         
Case Western Reserve University Active, not recruiting
Cleveland, Ohio, United States, 44106
Riverside Methodist Hospital Recruiting
Columbus, Ohio, United States, 43214
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
Grant Medical Center Recruiting
Columbus, Ohio, United States, 43215
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
Doctors Hospital Recruiting
Columbus, Ohio, United States, 43228
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
Columbus CCOP Recruiting
Columbus, Ohio, United States, 43215
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
The Mark H Zangmeister Center Recruiting
Columbus, Ohio, United States, 43219
Contact: John P. Kuebler    502-361-8496      
Principal Investigator: John P. Kuebler         
Mount Carmel Health Center West Recruiting
Columbus, Ohio, United States, 43222
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
Grady Memorial Hospital Recruiting
Delaware, Ohio, United States, 43015
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
Kettering Medical Center Recruiting
Kettering, Ohio, United States, 45429
Contact: Thomas J. Reid    937-298-3399    uchealthnews@uc.edu   
Principal Investigator: Thomas J. Reid         
Marietta Memorial Hospital Recruiting
Marietta, Ohio, United States, 45750
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
Hillcrest Hospital Cancer Center Recruiting
Mayfield Heights, Ohio, United States, 44124
Contact: Peter G. Rose    866-223-8100      
Principal Investigator: Peter G. Rose         
Lake University Ireland Cancer Center Active, not recruiting
Mentor, Ohio, United States, 44060
Licking Memorial Hospital Recruiting
Newark, Ohio, United States, 43055
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
Southern Ohio Medical Center Recruiting
Portsmouth, Ohio, United States, 45662
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
Springfield Regional Medical Center Recruiting
Springfield, Ohio, United States, 45505
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
Saint Ann's Hospital Recruiting
Westerville, Ohio, United States, 43081
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
Genesis HealthCare System Recruiting
Zanesville, Ohio, United States, 43701
Contact: John P. Kuebler    800-446-5532      
Principal Investigator: John P. Kuebler         
United States, Oklahoma
University of Oklahoma Health Sciences Center Recruiting
Oklahoma City, Oklahoma, United States, 73104
Contact: Robert S. Mannel    405-271-4272    julie-traylor@ouhsc.edu   
Principal Investigator: Robert S. Mannel         
Tulsa Cancer Institute Recruiting
Tulsa, Oklahoma, United States, 74146
Contact: Robert S. Mannel    405-271-4272    julie-traylor@ouhsc.edu   
Principal Investigator: Robert S. Mannel         
United States, Oregon
Compass Oncology Rose Quarter Terminated
Portland, Oregon, United States, 97227
Legacy Good Samaritan Hospital and Medical Center Recruiting
Portland, Oregon, United States, 97210
Contact: William E. Winter    503-280-1223      
Principal Investigator: William E. Winter         
United States, Pennsylvania
Abington Memorial Hospital Recruiting
Abington, Pennsylvania, United States, 19001
Contact: Parviz Hanjani    215-481-2402      
Principal Investigator: Parviz Hanjani         
Saint Luke's University Hospital-Bethlehem Campus Recruiting
Bethlehem, Pennsylvania, United States, 18015
Contact: Nicholas P. Taylor    610-954-3582    infolink@slhn.org   
Principal Investigator: Nicholas P. Taylor         
Geisinger Medical Center Recruiting
Danville, Pennsylvania, United States, 17822-2001
Contact: James R. Bosscher    570-271-5251    ehicks@sprg.mercy.net   
Principal Investigator: James R. Bosscher         
Fox Chase Cancer Center Recruiting
Philadelphia, Pennsylvania, United States, 19111-2497
Contact: Penny R. Anderson    215-728-4790      
Principal Investigator: Penny R. Anderson         
Temple University Hospital Recruiting
Philadelphia, Pennsylvania, United States, 19140
Contact: Enrique Hernandez    215-728-2983      
Principal Investigator: Enrique Hernandez         
Geisinger Wyoming Valley Recruiting
Wilkes-Barre, Pennsylvania, United States, 18711
Contact: James R. Bosscher    570-271-5251    ehicks@sprg.mercy.net   
Principal Investigator: James R. Bosscher         
United States, Rhode Island
Women and Infants Hospital Recruiting
Providence, Rhode Island, United States, 02905
Contact: Carolyn K. McCourt    401-274-1122      
Principal Investigator: Carolyn K. McCourt         
United States, South Dakota
Black Hills Obstetrics and Gynecology Recruiting
Rapid City, South Dakota, United States, 57701
Contact: Helen L. Frederickson    605-343-9224      
Principal Investigator: Helen L. Frederickson         
Avera Cancer Institute Recruiting
Sioux Falls, South Dakota, United States, 57105
Contact: Luis A. Rojas-Espaillat    800-657-4377    Jan.Healy@avera.org   
Principal Investigator: Luis A. Rojas-Espaillat         
United States, Tennessee
University of Tennessee - Knoxville Recruiting
Knoxville, Tennessee, United States, 37920
Contact: Larry C. Kilgore    865-544-9773      
Principal Investigator: Larry C. Kilgore         
United States, Texas
University of Texas Southwestern Medical Center Recruiting
Dallas, Texas, United States, 75390
Contact: David S. Miller    214-648-7097      
Principal Investigator: David S. Miller         
University of Texas Medical Branch at Galveston Recruiting
Galveston, Texas, United States, 77555-0565
Contact: Lyuba Levine    409-772-1950    clinical.research@utmb.edu   
Principal Investigator: Lyuba Levine         
M D Anderson Cancer Center Active, not recruiting
Houston, Texas, United States, 77030
Methodist Hospital Recruiting
Houston, Texas, United States, 77030
Contact: Aparna A. Kamat    713-790-2700      
Principal Investigator: Aparna A. Kamat         
United States, Utah
Sandra L Maxwell Cancer Center Recruiting
Cedar City, Utah, United States, 84720
Contact: Jeffrey E. Lee    713-792-3245      
Principal Investigator: Jeffrey E. Lee         
Intermountain Medical Center Recruiting
Murray, Utah, United States, 84157
Contact: Jeffrey E. Lee    713-792-3245      
Principal Investigator: Jeffrey E. Lee         
McKay-Dee Hospital Center Recruiting
Ogden, Utah, United States, 84403
Contact: Jeffrey E. Lee    713-792-3245      
Principal Investigator: Jeffrey E. Lee         
Utah Valley Regional Medical Center Recruiting
Provo, Utah, United States, 84604-3337
Contact: Jeffrey E. Lee    713-792-3245      
Principal Investigator: Jeffrey E. Lee         
Dixie Medical Center Regional Cancer Center Recruiting
Saint George, Utah, United States, 84770
Contact: Jeffrey E. Lee    713-792-3245      
Principal Investigator: Jeffrey E. Lee         
Huntsman Cancer Institute/University of Utah Recruiting
Salt Lake City, Utah, United States, 84112
Contact: Matthew M. Poppe    801-581-4477    clinical.trials@hci.utah.edu   
Principal Investigator: Matthew M. Poppe         
Utah Cancer Specialists-Salt Lake City Recruiting
Salt Lake City, Utah, United States, 84106
Contact: Jeffrey E. Lee    713-792-3245      
Principal Investigator: Jeffrey E. Lee         
LDS Hospital Recruiting
Salt Lake City, Utah, United States, 84143
Contact: Jeffrey E. Lee    713-792-3245      
Principal Investigator: Jeffrey E. Lee         
United States, Virginia
Naval Medical Center - Portsmouth Active, not recruiting
Portsmouth, Virginia, United States, 23708-2197
Virginia Commonwealth University Recruiting
Richmond, Virginia, United States, 23298
Contact: Weldon E. Chafe    804-628-1939      
Principal Investigator: Weldon E. Chafe         
United States, Washington
PeaceHealth Medical Group PC Recruiting
Bellingham, Washington, United States, 98226
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Harrison Medical Center Recruiting
Bremerton, Washington, United States, 98310
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Harrison HealthPartners Hematology and Oncology-Bremerton Recruiting
Bremerton, Washington, United States, 98310
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Providence Regional Cancer Partnership Recruiting
Everett, Washington, United States, 98201
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Skagit Valley Hospital Regional Cancer Care Center Recruiting
Mount Vernon, Washington, United States, 98273
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Harrison HealthPartners Hematology and Oncology-Poulsbo Recruiting
Poulsbo, Washington, United States, 98370
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Group Health Cooperative-Seattle Recruiting
Seattle, Washington, United States, 98112
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Swedish Medical Center-First Hill Recruiting
Seattle, Washington, United States, 98122-4307
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Fred Hutchinson Cancer Research Center Recruiting
Seattle, Washington, United States, 98109
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Pacific Gynecology Specialists Recruiting
Seattle, Washington, United States, 98104
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Northwest Hospital Recruiting
Seattle, Washington, United States, 98133
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
University of Washington Medical Center Recruiting
Seattle, Washington, United States, 98195
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Seattle Cancer Care Alliance Recruiting
Seattle, Washington, United States, 98109
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Olympic Medical Cancer Care Center Recruiting
Sequim, Washington, United States, 98384
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Rockwood Cancer Treatment Center-Downtown Recruiting
Spokane, Washington, United States, 99204
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Cancer Care Northwest - Spokane South Recruiting
Spokane, Washington, United States, 99202
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Tacoma General Hospital Terminated
Tacoma, Washington, United States, 98405
Saint Joseph Medical Center Recruiting
Tacoma, Washington, United States, 98405
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Providence Saint Mary Regional Cancer Center Recruiting
Walla Walla, Washington, United States, 99362
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
Wenatchee Valley Medical Center Recruiting
Wenatchee, Washington, United States, 98801
Contact: Benjamin E. Greer    206-616-8289      
Principal Investigator: Benjamin E. Greer         
United States, Wisconsin
Aurora Cancer Care-Grafton Recruiting
Grafton, Wisconsin, United States, 53024
Contact: Peter R. Johnson    800-252-2990      
Principal Investigator: Peter R. Johnson         
Aurora BayCare Medical Center Recruiting
Green Bay, Wisconsin, United States, 54311-6519
Contact: Peter R. Johnson    800-252-2990      
Principal Investigator: Peter R. Johnson         
Gundersen Lutheran Recruiting
La Crosse, Wisconsin, United States, 54601
Contact: Kurt Oettel    608-775-2385    cancerctr@gundluth.org   
Principal Investigator: Kurt Oettel         
University of Wisconsin Hospital and Clinics Recruiting
Madison, Wisconsin, United States, 53792
Contact: David M. Kushner    877-405-6866      
Principal Investigator: David M. Kushner         
Vince Lombardi Cancer Clinic-Marinette Recruiting
Marinette, Wisconsin, United States, 54143
Contact: Peter R. Johnson    800-252-2990      
Principal Investigator: Peter R. Johnson         
Aurora Saint Luke's Medical Center Recruiting
Milwaukee, Wisconsin, United States, 53215
Contact: Peter R. Johnson    800-252-2990      
Principal Investigator: Peter R. Johnson         
Aurora Sinai Medical Center Recruiting
Milwaukee, Wisconsin, United States, 53233
Contact: Peter R. Johnson    800-252-2990      
Principal Investigator: Peter R. Johnson         
Froedtert and the Medical College of Wisconsin Recruiting
Milwaukee, Wisconsin, United States, 53226
Contact: William H. Bradley    414-805-4380      
Principal Investigator: William H. Bradley         
Cancer Center of Western Wisconsin Recruiting
New Richmond, Wisconsin, United States, 54017
Contact: Matthew P. Boente    952-993-1517    MMCCOP@parknicollet.com   
Principal Investigator: Matthew P. Boente         
Vince Lombardi Cancer Clinic - Oshkosh Recruiting
Oshkosh, Wisconsin, United States, 54904
Contact: Peter R. Johnson    800-252-2990      
Principal Investigator: Peter R. Johnson         
Vince Lombardi Cancer Clinic-Sheboygan Recruiting
Sheboygan, Wisconsin, United States, 53081
Contact: Peter R. Johnson    800-252-2990      
Principal Investigator: Peter R. Johnson         
Aurora Medical Center in Summit Recruiting
Summit, Wisconsin, United States, 53066
Contact: Peter R. Johnson    800-252-2990      
Principal Investigator: Peter R. Johnson         
Vince Lombardi Cancer Clinic Recruiting
Two Rivers, Wisconsin, United States, 54241
Contact: Peter R. Johnson    800-252-2990      
Principal Investigator: Peter R. Johnson         
Aurora Women's Pavilion of Aurora West Allis Medical Center Recruiting
West Allis, Wisconsin, United States, 53227
Contact: Peter R. Johnson    800-252-2990      
Principal Investigator: Peter R. Johnson         
Japan
Tohoku University School of Medicine Recruiting
Sendai, Aoba-ku, Japan, 980-8574
Contact: Nobuo Yaegashi       med-som@bureau.tohoku.ac.jp   
Principal Investigator: Nobuo Yaegashi         
Kure National Hospital Recruiting
Kure, Hiroshima, Japan, 737
Contact: Hiroko Nakamura    (0823) 22-3111      
Principal Investigator: Hiroko Nakamura         
Iwate Medical University School of Medicine Recruiting
Morioka, Iwate, Japan, 020-8505
Contact: Toru Sugiyama    019-651-5111      
Principal Investigator: Toru Sugiyama         
Niigata University Medical and Dental Hospital Active, not recruiting
Niigata City, Niigata, Japan, 951-8520
Shizuoka Cancer Center Recruiting
Shizuoka City, Suntou, Japan, 411-8777
Contact: Hiroshi Fuji    888-823-5923    ctsucontact@westat.com   
Principal Investigator: Hiroshi Fuji         
Kagoshima City Hospital Recruiting
Kagoshima City, Kagoshima, Japan, 892-8580
Contact: Masayuki Hatae    011 81 099 224 2101      
Principal Investigator: Masayuki Hatae         
Shikoku Cancer Center Recruiting
Matsuyama, Japan, 791-0280
Contact: Takayoshi Nogawa    089-999-1172      
Principal Investigator: Takayoshi Nogawa         
Kinki University Recruiting
Osaka, Osaka, Japan, 589 8511
Contact: Masaki Mandai    072-366-0221      
Principal Investigator: Masaki Mandai         
Korea, Republic of
Keimyung University-Dongsan Medical Center Recruiting
Jung-Ku, Daegu, Korea, Republic of, 700-712
Contact: Chi-Heum Cho       ho@dsmc.or.kr   
Principal Investigator: Chi-Heum Cho         
National Cancer Center-Korea Recruiting
Goyang-si, Gyeonggi-do, Korea, Republic of, 410-769
Contact: Sang Y. Park    011-82-760-2384      
Principal Investigator: Sang Y. Park         
Inha University Active, not recruiting
Jung-gu, Incheon, Korea, Republic of, 400-711
Catholic University of Korea-Seoul Saint Mary's Hospital Active, not recruiting
Seoul, Korea, Korea, Republic of, 137-040
Samsung Medical Center Recruiting
Seoul, Korea, Korea, Republic of, 135-710
Contact: Duk-Soo Bae    011-82-1599-3114      
Principal Investigator: Duk-Soo Bae         
Seoul National University Bundang Hospital Recruiting
Seongnam City, Kyeonggi-do, Korea, Republic of, 463-707
Contact: Kidong Kim    011-82-02-9702-114      
Principal Investigator: Kidong Kim         
Asan Medical Center Recruiting
Seoul, Korea, Republic of, 138-736
Contact: Young-Tak Kim    irbksh@amc.seoul.kr    irbksh@amc.seoul.kr   
Principal Investigator: Young-Tak Kim         
Seoul National University Hospital Recruiting
Seoul, Korea, Republic of, 110-744
Contact: Jae W. Kim    011-82-760-2384      
Principal Investigator: Jae W. Kim         
Gangnam Severance Hospital Recruiting
Seoul, Korea, Republic of, 135-720
Contact: Jae-Hoon Kim       clinical.trial@bms.com   
Principal Investigator: Jae-Hoon Kim         
Korea Cancer Center Hospital Recruiting
Seoul, Korea, Republic of, 139-706
Contact: Beob-Jong Kim    011-82-02-9702-114      
Principal Investigator: Beob-Jong Kim         
Ajou University Hospital Active, not recruiting
Suwon, Korea, Republic of, 443-721
Sponsors and Collaborators
Gynecologic Oncology Group
Investigators
Principal Investigator: Sang Ryu Gynecologic Oncology Group
  More Information

No publications provided

Responsible Party: Gynecologic Oncology Group
ClinicalTrials.gov Identifier: NCT01101451     History of Changes
Other Study ID Numbers: GOG-0263, NCI-2011-02037, GOG-0263, CDR0000670125, GOG-0263, GOG-0263, U10CA027469
Study First Received: April 9, 2010
Last Updated: March 7, 2014
Health Authority: United States: Food and Drug Administration

Additional relevant MeSH terms:
Adenocarcinoma
Carcinoma
Carcinoma, Squamous Cell
Uterine Cervical Neoplasms
Carcinoma, Adenosquamous
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms
Neoplasms, Squamous Cell
Uterine Neoplasms
Genital Neoplasms, Female
Urogenital Neoplasms
Neoplasms by Site
Uterine Cervical Diseases
Uterine Diseases
Genital Diseases, Female
Neoplasms, Complex and Mixed
Cisplatin
Antineoplastic Agents
Therapeutic Uses
Pharmacologic Actions
Radiation-Sensitizing Agents
Physiological Effects of Drugs

ClinicalTrials.gov processed this record on April 22, 2014