Reduction of Abdominal Obesity and Insulin Resistance in Women

This study has been completed.

First Received on April 21, 2008. Last Updated on April 22, 2008 History of Changes

Sponsor:	Queen's University
Collaborator:	Canadian Institutes of Health Research (CIHR)
Information provided by:	Queen's University
ClinicalTrials.gov Identifier:	NCT00664495

Purpose

The purpose of the study was to assess the effects of equivalent diet- or exercise-induced weight loss and related insulin resistance in abdominally obese women.

Condition	Intervention
Obesity	Behavioral: Diet Weight Loss Behavioral: Exercise Weight Loss Behavioral: Exercise Without Weight Loss

Study Type:	Interventional
Study Design:	Allocation: Randomized Intervention Model: Parallel Assignment Primary Purpose: Treatment
Official Title:	Reduction of Abdominal Obesity and Insulin Resistance in Women

Resource links provided by NLM:

MedlinePlus related topics: Diabetes Medicines Exercise and Physical Fitness Obesity Weight Control

Drug Information available for: Insulin Insulin beef

U.S. FDA Resources

Further study details as provided by Queen's University:

Primary Outcome Measures:

Abdominal Obesity [ Time Frame: 4 months ] [ Designated as safety issue: No ]
Insulin Resistance [ Time Frame: 4 Months ] [ Designated as safety issue: No ]

Study Start Date:	April 1999
Study Completion Date:	December 2003
Primary Completion Date:	December 2003 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
No Intervention: C Control
Active Comparator: DWL Diet Weight Loss	Behavioral: Diet Weight Loss
Active Comparator: EWL Exercise Weight Loss	Behavioral: Exercise Weight Loss
Active Comparator: EWS Exercise Without Weight Loss	Behavioral: Exercise Without Weight Loss

Eligibility

Ages Eligible for Study:	20 Years to 50 Years
Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Premenopausal women

Exclusion Criteria:

Smokers and diabetics

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00664495

Locations

Canada, Ontario
Queen's University
Kingston, Ontario, Canada, K7L 3N6

Sponsors and Collaborators

Queen's University

Canadian Institutes of Health Research (CIHR)

Investigators

Principal Investigator:

Robert Ross, PhD

Queen's University

More Information

Publications:

Ross R, Janssen I, Dawson J, Kungl AM, Kuk JL, Wong SL, Nguyen-Duy TB, Lee S, Kilpatrick K, Hudson R. Exercise-induced reduction in obesity and insulin resistance in women: a randomized controlled trial. Obes Res. 2004 May;12(5):789-98.

Responsible Party:	Queen's University
ClinicalTrials.gov Identifier:	NCT00664495 History of Changes
Other Study ID Numbers:	Ross 1999
Study First Received:	April 21, 2008
Last Updated:	April 22, 2008
Health Authority:	Canada: Canadian Institutes of Health Research

Keywords provided by Queen's University:

Obesity, exercise, diet, insulin resistance

Additional relevant MeSH terms:

Insulin Resistance
Obesity
Obesity, Abdominal
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases
Overnutrition
Nutrition Disorders

Overweight
Body Weight
Signs and Symptoms
Insulin
Hypoglycemic Agents
Physiological Effects of Drugs
Pharmacologic Actions

ClinicalTrials.gov processed this record on February 12, 2012