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| Sponsor: | Lehigh Valley Hospital |
|---|---|
| Information provided by: | Lehigh Valley Hospital |
| ClinicalTrials.gov Identifier: | NCT00641797 |
Purpose
Benign Paroxysmal Positional Vertigo (BPPV) is a common complaint of emergency department patients. The importance of early diagnosis and treatment can lead to a much improved quality of life for patients afflicted by this ailment. It is the purpose of this study to evaluate and examine two methods of treatment. Patients will be randomized to receive the more common conventional medication therapy versus the canalith repositioning technique. All patients enrolled into this study are emergency department patients who have been diagnosed with BPPV via a positive Dix-Hallpike Maneuver. The hypothesis of this study is that vestibular rehabilitation will allow for resolution of symptoms without the use of conventional medication therapy in the acute management of BPPV in the emergency department patient.
| Condition | Intervention |
|---|---|
|
Benign Paroxysmal Positional Vertigo |
Drug: Meclizine Other: Epley Maneuver Drug: Lorazepam Drug: Diphenhydramine Drug: Oldansetron |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Single Blind (Caregiver) Primary Purpose: Treatment |
| Official Title: | A Randomized Trial to Evaluate Resolution of Symptoms Using Vestibular Rehab Versus Conventional Therapy in Patients Presenting to the Emergency Department (ED) With Diagnosis of Benign Paroxysmal Positional Vertigo (BPPV) |
| Estimated Enrollment: | 30 |
| Study Start Date: | November 2006 |
| Estimated Study Completion Date: | December 2011 |
| Estimated Primary Completion Date: | October 2008 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Active Comparator: 1
Patients who received conventional medication therapy.
|
Drug: Meclizine
Other Name: Ativert
Drug: Lorazepam
Other Name: Valium
Drug: Diphenhydramine
Other Name: Benedryl
Drug: Oldansetron
Other Name: Zofran
|
|
Experimental: 2
Patients who receive vestibular rehabilitation
|
Other: Epley Maneuver
Patient has vestibular rehabilitation utilizing the Epley Maneuver.
Other Name: Canalith Repositioning Technique
|
Show Detailed Description
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| United States, Pennsylvania | |
| Lehigh Valley Hospital | |
| Allentown, Pennsylvania, United States, 18103 | |
| Principal Investigator: | David B. Burmeister, DO | Lehigh Valley Hospital |
More Information
| Responsible Party: | David B. Burmeister DO, FACEP, LVH |
| ClinicalTrials.gov Identifier: | NCT00641797 History of Changes |
| Other Study ID Numbers: | 2-2006123IRB# |
| Study First Received: | February 13, 2008 |
| Last Updated: | March 21, 2008 |
| Health Authority: | United States: Institutional Review Board |
|
Canalith Repositioning Technique Vertigo |
|
Emergencies Vertigo Dizziness Disease Attributes Pathologic Processes Vestibular Diseases Labyrinth Diseases Ear Diseases Otorhinolaryngologic Diseases Neurologic Manifestations Nervous System Diseases Signs and Symptoms Sensation Disorders Diphenhydramine Meclizine |
Lorazepam Promethazine Antiemetics Autonomic Agents Peripheral Nervous System Agents Physiological Effects of Drugs Pharmacologic Actions Central Nervous System Agents Therapeutic Uses Gastrointestinal Agents Histamine H1 Antagonists Histamine Antagonists Histamine Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action |