Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Non-Carrier)

This study has been completed.
Sponsor:
Collaborator:
Pfizer
Information provided by (Responsible Party):
JANSSEN Alzheimer Immunotherapy Research & Development, LLC
ClinicalTrials.gov Identifier:
NCT00574132
First received: December 10, 2007
Last updated: October 30, 2013
Last verified: October 2013
  Purpose

This is a multicenter, double-blind, placebo controlled, randomized, outpatient multiple dose study in male and female patients ages 50 to less than 89 years with mild to moderate AD. Approximately 230 study sites in the US and Canada and up to 35 sites outside of North America will be involved. Patients will be randomized to receive either bapineuzumab or placebo. Each patient's participation will last approximately 1.5 years.

Bapineuzumab is a humanized monoclonal antibody, which binds to and clears beta amyloid peptide, and is designed to provide antibodies to beta amyloid directly to the patient.


Condition Intervention Phase
Alzheimer's Disease
Drug: Bapineuzumab 0.5 mg/kg
Drug: Placebo Control
Drug: Bapineuzumab 1.0 m/kg
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy and Safety Trial of Bapineuzumab (AAB-001, ELN115727) In Patients With Mild to Moderate Alzheimer's Disease Who Are Apolipoprotein E4 Non- Carriers.

Resource links provided by NLM:


Further study details as provided by JANSSEN Alzheimer Immunotherapy Research & Development, LLC:

Primary Outcome Measures:
  • Cognitive and Functional [ Time Frame: 18 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Cognitive and Global [ Time Frame: 18 months ] [ Designated as safety issue: No ]
  • Imaging and biochemical biomarkers of disease status [ Time Frame: 18 months ] [ Designated as safety issue: No ]

Enrollment: 1331
Study Start Date: December 2007
Study Completion Date: June 2012
Primary Completion Date: June 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Bapineuzumab 0.5 mg/kg
infusion every 13 weeks for a total of 6 infusions
Drug: Bapineuzumab 0.5 mg/kg
infusion every 13 weeks for a total of 6 infusions
Other Name: AAB-001
Placebo Comparator: Placebo Control
infusion every 13 weeks for a total of 6 infusions.
Drug: Placebo Control
given by infusion every 13 weeks for a total of 6 infusions.
Experimental: Bapineuzumab 1.0 m/kg
infusion every 13 weeks for a total of 6 infusions.
Drug: Bapineuzumab 1.0 m/kg
infusion every 13 weeks for a total of 6 infusions
Other Name: AAB-001

  Eligibility

Ages Eligible for Study:   50 Years to 88 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Diagnosis of probable AD
  • Age from 50 to less than 89
  • Mini-Mental Status Exam score of 16-26 inclusive
  • Brain magnetic resonance imaging (MRI) scan consistent with the diagnosis of AD
  • Stable doses of medications (cholinesterase inhibitors and memantine allowed)
  • Caregiver able to attend all clinic visits with patient

Exclusion Criteria:

  • Significant neurological disease other than AD
  • Major psychiatric disorder
  • Significant systemic illness
  • History of stroke or seizure, autoimmune disease, myocardial infarction within the last 2 years
  • Smoking greater than 20 cigarettes per day
  • Anticonvulsants, anti-Parkinson's, anticoagulant, or narcotic medications
  • Prior treatment experimental immunotherapeutics or vaccines for AD
  • Women of childbearing potential
  • Presence of pacemakers, CSF shunts, or foreign metal objects in the eyes, skin or body
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00574132

  Hide Study Locations
Locations
United States, Alabama
University of Alabama Hospital (UAB)
Birmingham, Alabama, United States, 35205
United States, Arizona
Dedicated Clinical Research, Inc.
Goodyear, Arizona, United States, 85395
Banner Alzheimer's Institute
Phoenix, Arizona, United States, 85006
HOPE Research Institute, LLC
Phoenix, Arizona, United States, 85050
Banner Research Institute
Sun City, Arizona, United States, 85351
University of Arizona College of Medicine, Health Science Center
Tucson, Arizona, United States, 85724-5023
Northwest Neurospecialists, PLLC
Tucson, Arizona, United States, 85741
United States, Arkansas
Clinical Trials Inc.
Little Rock, Arkansas, United States, 72205
United States, California
East Bay Physicians Medical Group
Berkeley, California, United States, 94705
AVI Clinical Research
Carson, California, United States, 90746
ATP Clinical Research, Inc
Costa Mesa, California, United States, 92626
Pharmacology Research Institute
Encino, California, United States, 91316
Margolin Brain Institute
Fresno, California, United States, 93720
Neurology Center of North Orange County
Fullerton, California, United States, 92835
Integrated Medical and Behavioral Associates
Glendale, California, United States, 91204
Sun Valley Behavioral Medical Center
Imperial, California, United States, 92251
Coordinated Clinical Research
La Jolla, California, United States, 92037
University of California San Diego/Shela Marcos Alzheimer's Disease Research Center
La Jolla, California, United States, 92037
Senior Clinical Trials
Laguna Hills, California, United States, 92653
Collaborative Neuroscience Network
Long Beach, California, United States, 90806
Pharmacology Research Institute
Los Alamitos, California, United States, 90720
Vintage Institute for Clinical Research, Inc
Los Angeles, California, United States, 90035
UCLA Department of Neurology
Los Angeles, California, United States, 90095
Synergy Research
National City, California, United States, 91950
Pharmacology Research Institute
Newport Beach, California, United States, 92660
The Neurology Center
Oceanside, California, United States, 92056
University of California, Irvine Medical Center
Orange, California, United States, 92868
Neuro-Therapeutics Inc.
Pasadena, California, United States, 91105
The Southwest Institute for Clinical Research, Inc.
Rancho Mirage, California, United States, 92270
University of California, Davis, Alzheimer's Disease Center
Sacramento, California, United States, 95817
Sutter Neuroscience Medical Group
Sacramento, California, United States, 95816
Artemis Institute for Clinical Research
San Diego, California, United States, 92123
Sharp Mesa Vista Hospital
San Diego, California, United States, 92123
University of California, San Francisco
San Francisco, California, United States, 94117
San Francisco Clinical Research Center
San Francisco, California, United States, 94109
Neuropsychiatric Research Center of Orange County
Santa Ana, California, United States, 92701
Neurological Research Institute
Santa Monica, California, United States, 90404
Schuster Medical Research Institute
Sherman Oaks, California, United States, 91403
Diablo Clinical Research, Inc
Walnut Creek, California, United States, 94598
United States, Colorado
Alpine Clinical Research Center
Boulder, Colorado, United States, 80304
Mile High Research Center
Denver, Colorado, United States, 80218
Advanced Neurosciences Research, LLC
Fort Collins, Colorado, United States, 80528
United States, Connecticut
Associated Neurologists, PC
Danbury, Connecticut, United States, 06810
Associated Neurologists of Southern CT, P.C.
Fairfield, Connecticut, United States, 06824
Yale University School of Medicine, Alzheimer's Disease Research Unit
New Haven, Connecticut, United States, 06510
Institute for Neurodegenerative Disorders
New Haven, Connecticut, United States, 06510
Research Center for Clinical Studies, Inc
Norwalk, Connecticut, United States, 06851
Chase Medical Research, LLC
Waterbury, Connecticut, United States, 06708
United States, Delaware
Christiana Care Health Services
Newark, Delaware, United States, 19713
United States, District of Columbia
Georgetown University Medical Center
Washington, District of Columbia, United States, 20057
United States, Florida
JEM Research, LLC
Atlantis, Florida, United States, 33462
Bradenton Research Center, Inc
Bradenton, Florida, United States, 34205
Quantum Laboratories, Inc.
Deerfield Beach, Florida, United States, 33064
Brain Matters Research, Inc.
Delray Beach, Florida, United States, 33445
Neurologic Consultants, P.A.
Fort Lauderdale, Florida, United States, 33308
Clinical Physiology Associates, Inc.
Fort Myers, Florida, United States, 33916
Emerald Coast Mood & Memory, PA.
Fort Walton Beach, Florida, United States, 32547
Neuropsychiatric Research Center of Southwest Florida
Ft. Myers, Florida, United States, 33912
MD Clinical
Hallandale Beach, Florida, United States, 33009
Sunrise Clinical Research, Inc.
Hollywood, Florida, United States, 33021
Mayo Clinic College of Medicine
Jacksonville, Florida, United States, 32224
Neurology Associates
Maitland, Florida, United States, 32751
Melbourne International Medicine Associates, MIMA
Melbourne, Florida, United States, 32901
Miami Jewish Health Systems
Miami, Florida, United States, 33137
Pharmax Research Clinic, LLC
Miami, Florida, United States, 33126
Allied Clinical Trials, Inc.
Miami, Florida, United States, 33156
Renstar Medical Research
Ocala, Florida, United States, 34471
Medical Research Group of Central Florida
Orange City, Florida, United States, 32763
Compass Research, LLC
Orlando, Florida, United States, 32806
Palm Beach Neurological Center/Advanced Research Consultants
Palm Beach Gardens, Florida, United States, 33418
Broward Research Group, Inc.
Pembroke Pines, Florida, United States, 33026
Neurostudies, Inc
Port Charlotte, Florida, United States, 33952
Roskamp Institute
Sarasota, Florida, United States, 34243
Miami Research Associates
South Miami, Florida, United States, 33143
Suncoast Neuroscience Associates, Inc.
St Petersburg, Florida, United States, 33713
Meridien Research
St. Petersburg, Florida, United States, 33709
Johnnie B. Byrd Sr. Alzheimer's Center and Research Institute
Tampa, Florida, United States, 33613
University of South Florida Suncoast Alzheimer's and Gerontology Center
Tampa, Florida, United States, 33613
Stedman Clinical Trials
Tampa, Florida, United States, 33613
Axiom Clinical Research of Florida
Tampa, Florida, United States, 33609
Premiere Research Institute
West Palm Beach, Florida, United States, 33407
United States, Georgia
Emory University/School of Medicine
Atlanta, Georgia, United States, 30322
NeuroTrials Research, Inc.
Atlanta, Georgia, United States, 30342
MS Center of Atlanta
Atlanta, Georgia, United States, 30327
Medical Research and Health Education Foundation, Inc.
Columbus, Georgia, United States, 31909
Dekalb Neurology Associates
Decatur, Georgia, United States, 30033
Gwinnett Medical Center
Lawrenceville, Georgia, United States, 30045
United States, Illinois
Northwestern University Feinberg School of Medicine
Chicago, Illinois, United States, 60611
University of Chicago Medical Center
Chicago, Illinois, United States, 60637
Alexian Brothers Neurosciences Institute
Elk Grove Village, Illinois, United States, 60007
Methodist Medical Center of Illinois
Peoria, Illinois, United States, 61602
Southern Illinois University, School of Medicine
Springfield, Illinois, United States, 62794-9643
United States, Indiana
Elkhart Clinic, LLC
Elkhart, Indiana, United States, 46514
Fort Wayne Neurological Center
Fort Wayne, Indiana, United States, 46805
Indiana University School of Medicine
Indianapolis, Indiana, United States, 46202
United States, Kansas
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160
Kansas Multi-Specialist Group
Kansas City, Kansas, United States, 66112
Mid America Neuroscience Institute
Lenexa, Kansas, United States, 66214
United States, Kentucky
Associates in Neurology, PSC
Lexington, Kentucky, United States, 40513
University of Kentucky
Lexington, Kentucky, United States, 40536
Four Rivers Clinical Research
Paducah, Kentucky, United States, 42003
United States, Louisiana
Lake Charles Clinical Trials
Lake Charles, Louisiana, United States, 70629
Louisiana Research Associates, Inc.
New Orleans, Louisiana, United States, 70114
J. Gary Booker, MD, APMC
Shreveport, Louisiana, United States, 71104
Louisana State University Health Sciences Center
Shreveport, Louisiana, United States, 70112
United States, Maine
Maine Medical Partners Neurology
Scarborough, Maine, United States, 04074
United States, Maryland
University of Maryland
Baltimore, Maryland, United States, 21201
Johns Hopkins School of Medicine
Baltimore, Maryland, United States, 21224
CBH Health, LLC
Rockville, Maryland, United States, 20850
United States, Massachusetts
McLean Hospital
Belmont, Massachusetts, United States, 02478
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Boston University School of Medicine
Boston, Massachusetts, United States, 02118
ActivMed Practices and Research, Inc
Haverhill, Massachusetts, United States, 01830
Neurocare, Inc.
Newton, Massachusetts, United States, 02459
Neuroscience Research of the Berkshires
Pittsfield, Massachusetts, United States, 01201
Donald S. Marks, MD, P.C.
Plymouth, Massachusetts, United States, 02360
Memory Wellness Clinic
Springfield, Massachusetts, United States, 01104
Springfield Neurology Associates
Springfield, Massachusetts, United States, 01104
Coastal Research Associates, Inc.
Weymouth, Massachusetts, United States, 02190
United States, Michigan
University of Michigan
Ann Arbor, Michigan, United States, 48105
Henry Ford Hospital
Detroit, Michigan, United States, 48202
Michigan State University
East Lansing, Michigan, United States, 48824
Saint Mary's Health Care
Grand Rapids, Michigan, United States, 49503
Borgess Medical Center/Borgess Research Institute
Kalamazoo, Michigan, United States, 49048
United States, Minnesota
Mayo Clinic
Rochester, Minnesota, United States, 55905
United States, Mississippi
Precise Research Centers
Flowood, Mississippi, United States, 39232
Hattiesburg Clinic
Hattiesburg, Mississippi, United States, 39401
United States, Missouri
Saint Luke's Hospital, Mid America Brain and Stroke Institute
Kansas City, Missouri, United States, 64111
The Center for Pharmaceutical Research
Kansas City, Missouri, United States, 64114
St. Louis University School of Medicine
St. Louis, Missouri, United States, 63104
Washington University School of Medicine
St. Louis, Missouri, United States, 63108
United States, Montana
Deaconess Billings Clinical Research Center
Billings, Montana, United States, 59101
Advanced Neurology Specialists
Great Falls, Montana, United States, 59405
United States, Nebraska
University of Nebraska Medical Center
Omaha, Nebraska, United States, 68198
United States, Nevada
Cleveland Clinic Lou Ruvo Center for Brain Health
Las Vegas, Nevada, United States, 89106
United States, New Hampshire
Coastal Neurology, PA
Dover, New Hampshire, United States, 03820
Dartmouth Hitchcock Medical Center, Dept of Neurology
Lebanon, New Hampshire, United States, 03756
United States, New Jersey
Comprehensive Clinical Research
Berlin, New Jersey, United States, 08009
The Memory Enhancement Center of America, Inc.
Eatontown, New Jersey, United States, 07724
Alzheimer's Research Corporation (ARC)
Manchester, New Jersey, United States, 08759
The NeuroCognitive Institute
Mount Arlington, New Jersey, United States, 07856
Princeton Medical Institute
Princeton, New Jersey, United States, 08540
University of Medicine and Dentistry of New Jersey
Stratford, New Jersey, United States, 08084
Shore Neurology, P.A.
Toms River, New Jersey, United States, 08755
United States, New Mexico
University of New Mexico, Health Sciences Center
Albuquerque, New Mexico, United States, 87131
Albuquerque Neuroscience, Inc.
Albuquerque, New Mexico, United States, 87109
United States, New York
Upstate Clinical Research, LLC
Albany, New York, United States, 12205
Neurological Associates of Albany, P.C.
Albany, New York, United States, 12208
Neuroscience Research Center at Albany Medical Center
Albany, New York, United States, 12208
Social Psychiatry Research Institute
Brooklyn, New York, United States, 11235
Five Towns Neuroscience Research
Cedarhurst, New York, United States, 11516
Advanced Bio-Behavioral Sciences
Elmsford, New York, United States, 10523
Empire Neurology, PC
Latham, New York, United States, 12110
Neurological Care of CNY
Liverpool, New York, United States, 13088
Parker Jewish Institute for Health Care & Rehabilitation
New Hyde Park, New York, United States, 11040
NYU School of Medicine/Psychiatry
New York, New York, United States, 10016
Columbia University/Medical Center
New York, New York, United States, 10032
Mt. Sinai School of Medicine
New York, New York, United States, 10029
Dent Neurologic Institute
New York, New York, United States, 14226
Nathan S. Kline Institute for Psychiatric Research
Orangeburg, New York, United States, 10962
University of Rochester Medical Center @ Monroe Community Hospital
Rochester, New York, United States, 14620
United States, North Carolina
Duke University Medical Center
Durham, North Carolina, United States, 27710
Clinical Trials of America, Inc
Hickory, North Carolina, United States, 28601
New Hope Clinical Research
Hickory, North Carolina, United States, 28601
Raleigh Neurology Associates
Raleigh, North Carolina, United States, 27607
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States, 27157
United States, Ohio
Rakesh Ranjan, M.D. & Associates, Inc.
Beachwood, Ohio, United States, 44125
NeuroCare Center, Inc
Canton, Ohio, United States, 44718
Neuro-Behavioral Clinical Research, Inc
Canton, Ohio, United States, 44718
University Memory and Aging Center University Hospitals of Cleveland/Case Medical Center
Cleveland, Ohio, United States, 44120
Ohio State University
Columbus, Ohio, United States, 43210
Neurology Specialists, Inc.
Dayton, Ohio, United States, 45417
Neurology and Neuroscience Center of Ohio
Toledo, Ohio, United States, 43623
United States, Oklahoma
Lynn Health Science Institute
Oklahoma City, Oklahoma, United States, 73112
Red River Medical Research Center, LLC
Oklahoma City, Oklahoma, United States, 73112
United States, Oregon
Providence Medical Group-Medford Neurology
Medford, Oregon, United States, 97504
Oregon Health & Sciences University
Portland, Oregon, United States, 97239
Summit Research Group, Inc.
Portland, Oregon, United States, 97210
Providence Health Service System, AD Center, Brain Institute
Portland, Oregon, United States, 97225
United States, Pennsylvania
Abington Neurological Associates, Ltd
Abington, Pennsylvania, United States, 19001
Lehigh Valley Health Network
Allentown, Pennsylvania, United States, 18103
The Clinical Trial Center, LLC
Jenkintown, Pennsylvania, United States, 19046
Penn Memory Center
Philadelphia, Pennsylvania, United States, 19104
Jefferson Hospital for Neuroscience
Philadelphia, Pennsylvania, United States, 19107
Drexel University College of Medicine
Philadelphia, Pennsylvania, United States, 19102
Clinical Trials Research Services, LLC
Pittsburg, Pennsylvania, United States, 15206
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
United States, Rhode Island
Rhode Island Mood and Memory Research Institute
East Providence, Rhode Island, United States, 02914
Rhode Island Hospital
Providence, Rhode Island, United States, 02903
Butler Hospital
Providence, Rhode Island, United States, 02906
United States, South Carolina
Medical University of South Carolina
N. Charleston, South Carolina, United States, 29406
United States, South Dakota
Avera Research Institute
Sioux Falls, South Dakota, United States, 57105
United States, Tennessee
Neurology Clinic, PC
Cordova, Tennessee, United States, 38018
Psychiatric Consultants, PC
Franklin, Tennessee, United States, 37067
East Tennessee State University
Johnson City, Tennessee, United States, 37614-1707
Volunteer Research Group
Knoxville, Tennessee, United States, 37920
United States, Texas
Senior Adults Specialty Research (SASR)
Austin, Texas, United States, 78757
University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, United States, 75390
Texas Neurology, PA
Dallas, Texas, United States, 75214
InSite Clinical Research
DeSoto, Texas, United States, 75115
University of North Texas/Health Sciences Center-Fort Worth
Fort Worth, Texas, United States, 76106
Baylor College of Medicine
Houston, Texas, United States, 77030
Claghorn-Lesem Research Clinic, Ltd.
Houston, Texas, United States, 77008
Integra Clinical Research, LLC
San Antonio, Texas, United States, 78231
Innovative Clinical Trials
San Antonio, Texas, United States, 78229
Grayline Clinical Drug Trials, Inc
Wichita Falls, Texas, United States, 76309
United States, Utah
University of Utah, Dept of Neurology
Salt Lake City, Utah, United States, 84108
Wasatch Clinical Research
Salt Lake City, Utah, United States, 84107
United States, Vermont
The Memory Clinic
Bennington, Vermont, United States, 05201
Fletcher Allen Health Care
Burlington, Vermont, United States, 05401
United States, Virginia
Innovative Clinical Research Center
Alexandria, Virginia, United States, 22304
University of Virginia
Charlottesville, Virginia, United States, 22903
Alliance Research Group, LLC
Richmond, Virginia, United States, 23230
United States, Washington
University of Washington Veterans Affairs
Seattle, Washington, United States, 98108
Pacific Medical Centers
Seattle, Washington, United States, 98144
Wenatchee Valley Medical Center
Wenatchee, Washington, United States, 98801
United States, Wisconsin
University of Wisconson Medical School of Medicine and Public Health
Madison, Wisconsin, United States, 53705
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Independent Pyschiatric Consultants
Waukesha, Wisconsin, United States, 53188
Austria
Medizinische Universität Graz
Graz, Styria, Austria, 8036
Medizinische Universität Wien
Wien, Vienna, Austria, 1090
Canada, Alberta
University of Calgary, Foothills Medical Centre
Calgary, Alberta, Canada, T2N 4Z6
Canada, British Columbia
Medical Arts Health Research Group
Kamloops, British Columbia, Canada, V2C 1K7
Medical Arts Health Research Group
Kelowna, British Columbia, Canada, V1Y 3G8
Medical Arts Health Research Group
Penticton, British Columbia, Canada, V2A 5C8
University of British Columbia (UBC) Hospital
Vancouver, British Columbia, Canada, V5Z 3T7
Canada, Ontario
Hotel Dieu Hospital/Queens University Memorial Clinics
Kingston, Ontario, Canada, K7L 5G2
Saint Joseph's Health Care London, Saint Joseph's Hospital
London, Ontario, Canada, N6A 4V2
Parkwood Hospital
London, Ontario, Canada, N6C 5J1
Bruyere Continuing Care
Ottawa, Ontario, Canada, K1N 5C8
Kawartha Regional Memory Clinic
Peterborough, Ontario, Canada, K9H 2P4
Neurology Research Inch./Toronto Memory Program
Toronto, Ontario, Canada, M3B 2S7
Toronto Centre for Memory and Aging
Toronto, Ontario, Canada, M6M 3Z5
Ontario Shores Centre for Mental Health Scienes
Whitby, Ontario, Canada, L1N 5S9
Canada, Quebec
Neuro Rive-Sud Memory Clinic
Greenfield Park, Quebec, Canada, J4V 2J2
Hopital Maisonneuve-Rosemont, Comite d' ethique de la recherche
Montreal, Quebec, Canada, H1T 2M4
Jewish General Hospital
Montréal, Quebec, Canada, H3T 1E2
Diex Research Sherbrooke Inc.
Sherbrooke, Quebec, Canada, JIH 1Z1
Douglas Mental Health University Institute
Verdun, Quebec, Canada, H4H 1R3
Germany
Universitätsklinik Tübingen
Tübingen, Baden-wuerttemberg, Germany, 72076
Universitätsklinik Ulm
Ulm, Baden-wuerttemberg, Germany, 89081
Universitätsklinik Freiburg
Freiburg, Baden-Württemberg, Germany, 79106
Universitätsklinikum Ulm
Günzburg, Bayern, Germany, 89312
Ludwig-Maximilians-Universität München
München, Bayern, Germany, 80336
Klinikum Rechts der Isar der Technischen Universität München
München, Bayern, Germany, 81675
Universitätsklinikum Regensburg
Regensburg, Byern, Germany, 93053
Saint Josefs Hospital
Bochum, Nordrhein-westfalen, Germany, 44791
Universitätsklinikum des Saarlandes
Homburg/Saar, Saarland, Germany, 66421
AFL Arzneimittelforschung Leipzig GmbH
Leipzig, Sachen, Germany, 04107
ABX-CRO advanced pharmaceutical services Forschungsgesellschaft GmbH
Dresden, Saschen, Germany, 01307
UKE Hamburg
Hamburg, Germany, 20246
Sponsors and Collaborators
JANSSEN Alzheimer Immunotherapy Research & Development, LLC
Pfizer
  More Information

No publications provided by JANSSEN Alzheimer Immunotherapy Research & Development, LLC

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: JANSSEN Alzheimer Immunotherapy Research & Development, LLC
ClinicalTrials.gov Identifier: NCT00574132     History of Changes
Other Study ID Numbers: ELN115727-301
Study First Received: December 10, 2007
Last Updated: October 30, 2013
Health Authority: United States: Food and Drug Administration
Canada: Health Canada
Austria: Austrian Agency for Health and Food Safety (AGES)
Germany: Paul-Ehrlich-Institut (PEI)

Additional relevant MeSH terms:
Alzheimer Disease
Brain Diseases
Central Nervous System Diseases
Delirium, Dementia, Amnestic, Cognitive Disorders
Dementia
Mental Disorders
Nervous System Diseases
Neurodegenerative Diseases
Tauopathies

ClinicalTrials.gov processed this record on October 22, 2014