Cardiovascular Risk Assessment in Patients Treated With Caduet (RIGHT)

This study has been completed.
Sponsor:
Information provided by:
Pfizer
ClinicalTrials.gov Identifier:
NCT00297973
First received: February 27, 2006
Last updated: March 27, 2009
Last verified: April 2008
  Purpose

Compare the reduction in Framingham's predicted 10-year risk of a coronary event (6) in patients with hypertension and at least three other cardiovascular risk factors (including diabetic patients) seen in private practice and randomized to either Caduet or usual care.


Condition Intervention Phase
Hypertension
Procedure: Blood pressure measurements
Procedure: Blood samples
Phase 4

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Official Title: Cardiovascular Risk Assessment In Patients With Hypertension And At Least Three Other Risk Factors, Treated With Caduet Compared To Usual Care: The Right Study

Resource links provided by NLM:


Further study details as provided by Pfizer:

Primary Outcome Measures:
  • % reduction in Framingham's predicted 10-year risk of a coronary event between V1 and V3 in the Caduet group compared to the usual care group (6) (including diabetic patients)

Secondary Outcome Measures:
  • 1. % patients changing risk category between V1 and V3 2. % reduction in Framingham's predicted 10-year risk of a coronary event (8) excluding diabetic patients 3. Clinical and biological safety during treatment period

Enrollment: 1442
Study Start Date: February 2006
Study Completion Date: April 2007
  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • 1.Male or female, 18 years of age or over, 2.Patient with hypertension and at least three other CV risk factors, 3.Hypertension, treated or not, but not at the currently recommended goals (140/90 mmHg for most patients, 130/80 mmHg for patients with diabetes or nephropathy). In case of treated hypertension, patients should be on their current treatment for at least 4 weeks before randomisation,

Exclusion Criteria:

  • 1. Patient with a history of coronary heart disease, 2.Patients with a history of familial hypercholesterolemia, 3.Patient with malignant HTN, 4.Non-essential hypertension, 5.Known hypersensitivity to dihydropyridines, 6.Patients already receiving a dihydropyridine, 7.Known hypersensitivity to HMG-CoA-reductase inhibitors, 8.Patients currently receiving or who has received a HMG-CoA-reductase within the 3 months prior to selection, 9.Patients currently receiving or who has received a fibric acid, resins, ezetimibe, nicotinic acid and all other drug which is known to affect lipid levels, within 6 weeks prior to selection,
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00297973

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Locations
France
Pfizer Investigational Site
Abbeville, France, 80100
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Aire Sur La Lys, France, 62120
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Aix Les Bains, France, 73100
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Alencon, France, 61000
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Allaire, France, 56350
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Amboise, France, 37400
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Amiens, France, 80080
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Amiens, France, 80000
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Amiens Cedex 3, France, 80094
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Andrezieux Boutheon, France, 42160
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Angers, France, 49000
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Annecy, France, 74000
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Annecy Le Vieux, France, 74940
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Annemasse, France, 74100
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Anzin, France, 59410
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Appoigny, France, 89380
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Apt, France, 84400
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Argenteuil, France, 95100
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Arles, France, 13200
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Arneke, France, 59285
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Arpajon, France, 91290
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Arsac, France, 33460
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Aubagne, France, 13400
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Auchel, France, 62260
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Audresselles, France, 62164
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Autrans, France, 38880
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Balma, France, 31130
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Bastia, France, 20200
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Bayonne, France, 64100
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Beaucaire, France, 30300
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Beaumont Les Valence, France, 26760
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Beaurains, France, 62217
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Beausoleil, France, 06240
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Belley, France, 01300
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Belpech, France, 11420
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Benquet, France, 40280
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Berck, France, 62600
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Bersee, France, 59235
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Bethune, France, 62400
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Beziers, France, 34500
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Biarritz, France, 64200
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Blasimon, France, 33540
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Blois, France, 41000
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Boen, France, 42130
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Boersch, France, 67530
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Bondues, France, 59910
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Bondy, France, 93140
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Bordeaux, France, 33200
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Bordeaux, France, 33000
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Bourg St. Andeol, France, 07700
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Bourges, France, 18000
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Brehan, France, 56580
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Brest, France, 29200
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Brignoud, France, 38190
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Bruay La Buissiere, France, 62700
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Cabestany, France, 66330
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Caen, France, 14000
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Cagnes Sur Mer, France, 06800
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Cannes, France, 06400
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Cannes La Bocca, France, 06150
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Carnon Plage, France, 34280
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Castelnau Le Fez, France, 34170
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Castelsarrasin, France, 82100
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Castres, France, 81100
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Caylus, France, 82160
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Cergy, France, 95000
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Cestas, France, 33610
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Champagne Au Mont D'Or, France, 69410
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Chanceaux Sur Choisille, France, 37390
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Charleville Mezieres, France, 08000
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Chartres, France, 28000
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Chatou, France, 78400
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Chelles, France, 77500
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Chenove, France, 21300
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Chilly Mazarin, France, 91380
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Clairac, France, 47320
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Clary, France, 59225
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Clermont Ferrand, France, 63100
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Collioure, France, 66190
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Colombier Fontaine, France, 25260
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Colomiers, France, 31770
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Condat Sur Vienne, France, 87920
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Courthezon, France, 84350
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Craponne, France, 69290
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Crecy La Chapelle, France, 77580
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Crest, France, 26400
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Creteil, France, 94000
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Crotenay, France, 39300
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Cuise La Motte, France, 60350
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Denain, France, 59220
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Dijon, France, 21000
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Dugny Sur Meuse, France, 55100
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Dunkerque, France, 59140
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Echirolles, France, 38130
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Eckbolsheim, France, 67201
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Eckwersheim, France, 67550
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Epernay, France, 51200
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Epinal, France, 88000
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Epinay Sur Seine, France, 93800
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Etampes, France, 91150
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Etang Sur Arroux, France, 71190
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Evreux, France, 27000
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Falaise, France, 14700
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Fayence, France, 83440
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Fenioux, France, 79160
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Ferney Voltaire, France, 01210
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Fontaine, France, 38600
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Fontaine Les Dijon, France, 21121
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Fontainebleau, France, 77300
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Fontenay Sous Bois, France, 94120
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Fontes, France, 34320
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Fos Sur Mer, France, 13270
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Franconville, France, 95130
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Fumay, France, 08170
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Gaillefontaine, France, 76870
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Gambsheim, France, 67760
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Gap, France, 05000
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Gonesse, France, 95500
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Gonneville La Mallet, France, 76280
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Gradignan, France, 33170
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Grand Couronne, France, 76530
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Greasque, France, 13850
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Grendelbruch, France, 67190
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Grenoble, France, 38100
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Guise, France, 02120
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Haguenau, France, 67500
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Harnes, France, 62440
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Hasparren, France, 64240
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Hostens, France, 33125
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Ivry Sur Seine, France, 94200
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L'Isle Sur La Sorgue, France, 84800
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La Ciotat, France, 13600
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La Creche, France, 79260
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La Fere, France, 02800
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La Francheville, France, 08000
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La Grande Motte, France, 34280
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La Grande Paroisse, France, 77130
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LA Rochelle, France, 17000
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La Trinite Sur Mer, France, 56470
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Labastidette, France, 31600
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Lamagistere, France, 82360
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Lamarque, France, 33460
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Langon, France, 33210
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Lattes, France, 34970
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Laval, France, 53000
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Lavernose Lacasse, France, 31410
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Laxou, France, 54520
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Le Bourget, France, 93350
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Le Cannet, France, 06110
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Le Havre, France, 76620
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Le Havre, France, 76610
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Le Havre, France, 76600
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Lembeye, France, 64350
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Les Issambres, France, 83380
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Les Sables D'Olonne, France, 85100
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Lesquin, France, 59810
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Liancourt, France, 60140
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Ligny En Barrois, France, 55500
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Lille, France, 59000
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Lille, France, 59800
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Limoges, France, 87000
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Lorient, France, 56100
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Lourdes, France, 65100
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Lucheux, France, 80600
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Luxeuil Les Bains, France, 70300
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Lyon, France, 69008
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Lyon, France, 69009
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Mandelieu La Napoule, France, 06210
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Marcq En Baroeul, France, 59700
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Marseille, France, 13012
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Marseille, France, 13002
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Martigues, France, 13500
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Meaux Beauval, France, 77100
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Meaux-Beauval, France, 77100
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Mennecy, France, 91540
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Mensignac, France, 24350
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Merlimont, France, 62155
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Metz, France, 57000
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Mirabel Et Blacons, France, 26400
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Miramas, France, 13140
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Miramas Cedex, France, 13141
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Miramont De Guyenne, France, 47800
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Mittersheim, France, 57930
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Mommenheim, France, 67670
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Mons En Baroeul, France, 59370
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Montauroux, France, 83440
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Montbeliard, France, 25200
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Monteux, France, 84170
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Montpellier, France, 34000
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Montpellier, France, 34070
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Montreuil, France, 93100
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Montrevel En Bresse, France, 01340
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Moreuil, France, 80110
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Morlaix, France, 29600
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Mourenx, France, 64150
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Muespach, France, 68640
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Mulhouse, France, 68200
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Mulhouse, France, 68100
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Mundolsheim, France, 67450
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Nancy, France, 54000
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Nantes, France, 44200
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Nantes, France, 44100
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Nantes, France, 44000
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Neris Les Bains, France, 03310
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Nevers, France, 58000
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Nice, France, 06300
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Nice, France, 06 000
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Nice, France, 06200
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Nice, France, 06000
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Niort, France, 79000
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Nogent Sur Marne, France, 94130
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Noisiel, France, 77186
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Noyon, France, 60400
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Oberhausbergen, France, 67205
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Obernai, France, 67210
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Objat, France, 19130
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Orange, France, 84100
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Orchamps, France, 39700
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Orry La Ville, France, 60560
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Osses, France, 64780
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Pacy Sur Eure, France, 27210
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Palau Del Vidre, France, 66690
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Paris, France, 75019
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Paris, France, 75009
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Paris, France, 75013
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Paris, France, 75012
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Paris, France, 75015
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Paris, France, 75017
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Paris, France, 75018
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Paris, France, 75014
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Paris, France, 75116
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Paris, France, 75020
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Parthenay, France, 79200
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Perpignan, France, 66100
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Pessac, France, 33600
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Petit Couronne, France, 76650
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Pfulgriesheim, France, 67370
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Phalempin, France, 59133
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Pont A Mousson, France, 54700
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Portet Sur Garonne, France, 31120
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Porto Vecchio, France, 20137
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Poussan, France, 34560
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Pradines, France, 46090
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Precy Sur Oise, France, 60460
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Quimperle, France, 29300
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Rebais, France, 77510
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Reims, France, 51100
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Remiremont, France, 88200
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Rennes, France, 35200
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Rigney, France, 25640
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Rodez Cedex, France, 12001
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Rognac, France, 13340
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Rohrwiller, France, 67410
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Romans Sur Isere, France, 26100
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Roncq, France, 59223
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Roquevaire, France, 13360
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Roubaix, France, 59100
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Roubaix Cedex 1, France, 59071
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Rozay En Brie, France, 77540
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Saint Martin D'Oney, France, 40090
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Saint-etienne, France, 42000
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Salles, France, 33770
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Salon De Provence, France, 13300
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Sanary Sur Mer, France, 83110
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Sarlat La Caneda, France, 24200
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Sartrouville, France, 78500
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Schweighouse Sur Moder, France, 67590
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Selestat, France, 67600
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Semur En Auxois, France, 21140
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Sete, France, 34200
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Sevrier, France, 74320
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Soissons, France, 02200
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Solgne, France, 57420
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St. Agreve, France, 07320
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St. Avold, France, 57500
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St. Brieuc Cedex 1, France, 22015
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St. Denis, France, 93200
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St. Die Des Vosges, France, 88100
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St. Erme Outre Et Ramecourt, France, 02820
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St. Etienne, France, 42100
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St. Fons, France, 69190
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St. Germain Au Mont D'Or, France, 69650
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St. Germain De Marencennes, France, 17700
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St. Girons, France, 09200
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St. Jean De Braye, France, 45800
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St. Jean De Luz, France, 64500
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St. Jean De Maurienne, France, 73300
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St. Joachim, France, 44720
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St. Leu D'Esserent, France, 60340
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St. Leu La Foret, France, 95320
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St. Martin Du Bois, France, 49500
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St. Morillon, France, 33650
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St. Ouen, France, 93400
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St. Ouen L'Aumone, France, 95310
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St. Rambert D'Albon, France, 26140
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St. Raphael, France, 83700
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St. Remy De Provence, France, 13210
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St. Saulve, France, 59880
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St. Sebastien Sur Loire, France, 44230
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St. Sulpice, France, 81370
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St. Tropez, France, 83990
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St. Yrieix La Perche, France, 87500
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Ste. Maxime, France, 83120
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Ste. Suzanne, France, 53270
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Strasbourg, France, 67200
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Strasbourg, France, 67000
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Suresnes, France, 92150
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Targon, France, 33760
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Tergnier, France, 02700
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Thiant, France, 59224
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Thierville Sur Meuse, France, 55840
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Thiviers, France, 24800
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Thones, France, 74230
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Toul, France, 54200
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Toulon, France, 83000
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Toulon, France, 83200
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Toulouse, France, 31500
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Toulouse, France, 31100
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Toulouse, France, 31200
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Toulouse, France, 31400
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Toulouse, France, 31000
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Tours, France, 37000
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Trie Sur Baise, France, 65220
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Vabres L'Abbaye, France, 12400
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Vacqueyras, France, 84190
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Vagney, France, 88120
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Valenciennes, France, 59300
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Valognes, France, 50700
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Valreas, France, 84600
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Vals Les Bains, France, 07600
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Vandoeuvre Les Nancy, France, 54500
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Vannes, France, 56000
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Varces Allieres Et Risset, France, 38760
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Vatan, France, 36150
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Velines, France, 24230
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Velizy Villacoublay, France, 78140
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Vence, France, 06140
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Venissieux, France, 69200
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Vernet, France, 31810
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Viane, France, 81530
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Villard Bonnot, France, 38190
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Villefranche de Rouergue, France, 12200
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Villefranche Sur Mer, France, 06230
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Villefranche Sur Saone, France, 69400
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Villeneuve Les Maguelone, France, 34750
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Villeparisis, France, 77270
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Villers St. Paul, France, 60870
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Villette D'Anthon, France, 38280
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Viry Chatillon, France, 91170
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Vitrolles, France, 13127
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Vix, France, 85770
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Wambrechies, France, 59118
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Wasselonne, France, 67310
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Wattignies, France, 59139
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Wattrelos, France, 59150
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Witry Les Reims, France, 51420
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Yffiniac, France, 22120
Sponsors and Collaborators
Pfizer
Investigators
Study Director: Pfizer CT.gov Call Center Pfizer
  More Information

Additional Information:
No publications provided

ClinicalTrials.gov Identifier: NCT00297973     History of Changes
Other Study ID Numbers: A3841038
Study First Received: February 27, 2006
Last Updated: March 27, 2009
Health Authority: France: HAS - French Health Agency

Additional relevant MeSH terms:
Hypertension
Vascular Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on September 18, 2014