Carboplatin and Paclitaxel With or Without Bevacizumab in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Primary Peritoneal Cancer, or Fallopian Tube Cancer

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:
NCT00262847
First received: December 6, 2005
Last updated: June 18, 2014
Last verified: June 2014
  Purpose

This randomized phase III trial is studying carboplatin, paclitaxel, and bevacizumab to see how well they work compared to carboplatin, paclitaxel, and placebo in treating patients with stage III or stage IV ovarian epithelial, primary peritoneal cancer, or fallopian tube cancer. Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. It is not yet known whether carboplatin, paclitaxel, and bevacizumab are more effective than carboplatin, paclitaxel, and placebo in treating ovarian epithelial or primary peritoneal cancer , or fallopian tube cancer.


Condition Intervention Phase
Brenner Tumor
Fallopian Tube Cancer
Ovarian Clear Cell Cystadenocarcinoma
Ovarian Endometrioid Adenocarcinoma
Ovarian Mixed Epithelial Carcinoma
Ovarian Mucinous Cystadenocarcinoma
Ovarian Serous Cystadenocarcinoma
Ovarian Undifferentiated Adenocarcinoma
Primary Peritoneal Cavity Cancer
Stage III Ovarian Epithelial Cancer
Stage IV Ovarian Epithelial Cancer
Other: hydrocortisone/placebo
Drug: paclitaxel
Drug: carboplatin
Biological: bevacizumab
Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Treatment
Official Title: A Phase III Trial of Carboplatin and Paclitaxel Plus Placebo Versus Carboplatin and Paclitaxel Plus Concurrent Bevacizumab (NSC # 704865) Followed by Placebo, Versus Carboplatin and Paclitaxel Plus Concurrent and Extended Bevacizumab, in Women With Newly Diagnosed, Previously Untreated, Suboptimal Advanced Stage Epithelial Ovarian, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Resource links provided by NLM:


Further study details as provided by National Cancer Institute (NCI):

Primary Outcome Measures:
  • Progression-free Survival [ Time Frame: From study entry until first disease progression, death or date of last contact, up to 6 years ] [ Designated as safety issue: No ]
    Median progression-free survival (PFS). Onset of progression could be based on radiographic (RECIST) criteria or rising CA-125 (GCIG criteria).


Secondary Outcome Measures:
  • Overall Survival [ Time Frame: From study entry to death or last contact, up to 6 years ] [ Designated as safety issue: No ]
    Median overall survival (OS)

  • Frequency and Severity of Adverse Events Assessed by Common Terminology Criteria for Adverse Events Version 3.0 [ Time Frame: Up to 5 years ] [ Designated as safety issue: Yes ]
  • Impact on Quality of Life Measured by the Functional Assessment of Cancer Therapy-Ovary Trial Outcome Index (FACT-O TOI) [ Time Frame: At baseline, 9, 18, 36, 60, and 84 weeks ] [ Designated as safety issue: No ]
    Estimated least squares means from a mixed module of Quality of Life (QOL) scores at each assessment point, adjusted for baseline score and patient's age. Note: The range of possible scores of the FACT-O TOI is 0 - 104 for all treatment groups and at all visits. A higher score indicates better QOL. Baseline mean scores are raw means.


Enrollment: 1873
Study Start Date: September 2005
Primary Completion Date: November 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Arm I (placebo, paclitaxel, carboplatin)
Patients receive paclitaxel IV over 3 hours and carboplatin IV over 30 minutes on day 1. Beginning in course 2, patients also receive placebo IV over 30-90 minutes on day 1. Treatment repeats every 21 days for 6 courses. Beginning in course 7, patients receive placebo alone IV over 30-90 minutes on day 1. Treatment with placebo repeats every 21 days for up to 22 courses in the absence of disease progression or unacceptable toxicity.
Other: hydrocortisone/placebo
Given IV
Drug: paclitaxel
Given IV
Other Names:
  • Anzatax
  • Asotax
  • TAX
  • Taxol
Drug: carboplatin
Given IV
Other Names:
  • Carboplat
  • CBDCA
  • JM-8
  • Paraplat
  • Paraplatin
Experimental: Arm II (placebo, paclitaxel, carboplatin, bevacizumab)
Patients receive paclitaxel and carboplatin as in arm I. Beginning in course 2, patients also receive bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 21 days for 6 courses. Beginning in course 7, patients receive placebo alone IV over 30-90 minutes on day 1. Treatment with placebo repeats every 21 days for up to 22 courses in the absence of disease progression or unacceptable toxicity.
Other: hydrocortisone/placebo
Given IV
Drug: paclitaxel
Given IV
Other Names:
  • Anzatax
  • Asotax
  • TAX
  • Taxol
Drug: carboplatin
Given IV
Other Names:
  • Carboplat
  • CBDCA
  • JM-8
  • Paraplat
  • Paraplatin
Biological: bevacizumab
Given IV
Other Names:
  • anti-VEGF humanized monoclonal antibody
  • anti-VEGF monoclonal antibody
  • Avastin
  • rhuMAb VEGF
Experimental: Arm III (paclitaxel, carboplatin, bevacizumab)
Patients receive paclitaxel and carboplatin as in arm I. Beginning in course 2, patients also receive bevacizumab IV over 30-90 minutes on day 1. Treatment repeats every 21 days for 6 courses. Beginning in course 7, patients receive bevacizumab alone IV over 30-90 minutes on day 1. Treatment with bevacizumab repeats every 21 days for up to 22 courses in the absence of disease progression or unacceptable toxicity.
Drug: paclitaxel
Given IV
Other Names:
  • Anzatax
  • Asotax
  • TAX
  • Taxol
Drug: carboplatin
Given IV
Other Names:
  • Carboplat
  • CBDCA
  • JM-8
  • Paraplat
  • Paraplatin
Biological: bevacizumab
Given IV
Other Names:
  • anti-VEGF humanized monoclonal antibody
  • anti-VEGF monoclonal antibody
  • Avastin
  • rhuMAb VEGF

  Show Detailed Description

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Histologically confirmed ovarian epithelial, primary peritoneal*, or fallopian tube cancer

    • Stage III with any gross (macroscopic or palpable) residual disease OR stage IV disease
  • The following histologic epithelial cell types are allowed provided the histologic features of the tumor are compatible with a primary müllerian epithelial adenocarcinoma:

    • Serous adenocarcinoma
    • Endometrioid adenocarcinoma
    • Mucinous adenocarcinoma
    • Undifferentiated carcinoma
    • Clear cell adenocarcinoma
    • Mixed epithelial carcinoma
    • Transitional cell carcinoma
    • Malignant Brenner tumor
    • Adenocarcinoma not otherwise specified
  • No borderline ovarian epithelial tumor (formerly "tumors of low malignant potential")

    • Prior diagnosis of a borderline tumor that was surgically resected and an unrelated, new, invasive ovarian epithelial or primary peritoneal cancer that subsequently develops is allowed provided there was no prior chemotherapy for any ovarian tumor
  • No recurrent invasive ovarian epithelial cancer treated with surgery only (e.g., stage IA or IB low-grade epithelial ovarian or fallopian tube cancer)
  • No synchronous primary endometrial cancer or prior primary endometrial cancer unless all of the following criteria are met:

    • Stage ≤ IB
    • Superficial myometrial invasion without vascular or lymphatic invasion
    • No poorly differentiated subtypes (i.e., papillary serous, clear cell, or other FIGO grade 3 lesions)
  • Must have undergone surgery for ovarian epithelial, primary peritoneal, or fallopian tube cancer in the past 1-12 weeks AND have tissue available for histologic evaluation

    • Patients with stage III disease in which the largest maximal diameter of any residual tumor implant a the completion of initial surgery is ≤ 1 cm will be defined as "optimal" (all others will be defined as "suboptimal")
  • Measurable or nonmeasurable disease
  • No tumor involving active major vessels
  • No prior or concurrent CNS disease, including primary brain tumor or brain metastases
  • Performance status - GOG 0-2
  • Absolute neutrophil count ≥ 1,500/mm^3 without induction or support by granulocyte colony stimulating factors
  • Platelet count ≥ 100,000/mm^3
  • No active bleeding
  • No known bleeding disorder or coagulopathy
  • Bilirubin ≤ 1.5 times upper limit of normal (ULN)
  • SGOT ≤ 2.5 times ULN
  • Alkaline phosphatase ≤ 2.5 times ULN
  • INR ≤ 1.5 (2-3 with stable-dose therapeutic warfarin for management of venous thrombosis including pulmonary thromboembolus)
  • PTT < 1.2 times ULN
  • No acute hepatitis
  • Creatinine ≤ 1.5 times ULN
  • Urine protein:creatinine ratio < 1.0
  • Urine protein < 1 g/24-hr urine collection
  • No New York Heart Association class II-IV congestive heart failure
  • No myocardial infarction or unstable angina within the past 6 months
  • No uncontrolled hypertension (i.e., blood pressure > 150/90 mm Hg)
  • No serious cardiac arrhythmia requiring medication except for patients with asymptomatic atrial fibrillation with a controlled ventricular rate
  • No other clinically significant cardiovascular disease
  • No clinically significant peripheral vascular disease ≥ grade 2
  • No history of cerebral vascular accident, transient ischemic attack, or subarachnoid hemorrhage within the past 6 months
  • Not pregnant or nursing
  • Negative pregnancy test
  • Fertile patients must use effective contraception during and for 6 months after completion of study treatment
  • No neuropathy (sensory and motor) > grade 1
  • No known hypersensitivity to Chinese hamster ovary cell products or recombinant human or humanized antibodies
  • No other malignancy within the past 5 years except nonmelanoma skin cancer
  • No active infection that requires parenteral antibiotics
  • No serious nonhealing wound, ulcer, or bone fracture
  • No history of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess within the past 28 days

    • Granulating incisions healing by secondary intention with no evidence of fascial dehiscence or infection are allowed
  • No other pathological condition that would confer a high risk of bleeding
  • No uncontrolled seizures
  • No significant traumatic injury within the past 4 weeks
  • No clinical symptoms or signs of gastrointestinal obstruction that require parenteral hydration and/or nutrition
  • No other medical history or condition that, in the opinion of the investigator, would preclude study participation
  • No prior targeted therapy for ovarian epithelial or peritoneal primary cancer, including, but not limited to, any of the following:

    • Vaccines
    • Antibodies
    • Tyrosine kinase inhibitors
  • No prior bevacizumab
  • No other prior antivascular endothelial growth factors (VEGF)
  • No other concurrent biologic therapy
  • No other concurrent cytotoxic or anticancer therapy
  • No prior chemotherapy for abdominal or pelvic tumor including neoadjuvant chemotherapy for their ovarian or primary peritoneal cancer
  • More than 3 years since prior adjuvant chemotherapy for localized breast cancer AND patient remains free of recurrent or metastatic disease
  • No other concurrent chemotherapy
  • Ovarian estrogen with or without progestin replacement therapy as indicated at the lowest effective dose(s) for control of menopausal symptoms at any time allowed

    • No progestins for management of anorexia while on study-directed therapy or prior to disease progression
  • No prior hormonal therapy for ovarian, peritoneal primary, or fallopian tube cancer
  • No concurrent hormonal therapy
  • More than 3 years since prior radiotherapy for localized cancer of the breast, head and neck, or skin AND patient remains free of recurrent or metastatic disease
  • No prior radiotherapy to the abdominal cavity or pelvis
  • No concurrent radiotherapy
  • No concurrent amifostine or other protective reagents
  • At least 4 weeks since prior major surgical procedure or open biopsy
  • At least 1 week since prior core biopsy
  • No concurrent major surgery including abdominal surgery (laparotomy or laparoscopy) prior to disease progression (e.g., colostomy or enterostomy reversal, interval or secondary cytoreductive surgery, or second look surgery
  • No prior cancer therapy that would preclude study treatment
  • No concurrent consolidation or maintenance therapy
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00262847

  Hide Study Locations
Locations
United States, Alabama
Northeast Alabama Regional Medical Center
Anniston, Alabama, United States, 36202
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
Clearview Cancer Institute
Huntsville, Alabama, United States, 35805
Mobile Infirmary Medical Center
Mobile, Alabama, United States, 36607
United States, Arizona
Banner Thunderbird Medical Center
Glandale, Arizona, United States, 85306
Banner Baywood Medical Center
Mesa, Arizona, United States, 85206
Banner Desert Medical Center
Mesa, Arizona, United States, 85202
Western Regional CCOP
Phoenix, Arizona, United States, 85006
Banner Good Samaritan Medical Center
Phoenix, Arizona, United States, 85006
Mayo Clinic in Arizona
Scottsdale, Arizona, United States, 85259
United States, Arkansas
Highlands Oncology Group PA - Fayetteville
Fayetteville, Arkansas, United States, 72703
Washington Regional Medical Center - Fayetteville
Fayetteville, Arkansas, United States, 72703
Saint Edward Mercy Medical Center
Ft. Smith, Arkansas, United States, 72903
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States, 72205
United States, California
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California, United States, 91505
Valley Medical Oncology Consultants-Castro Valley
Castro Valley, California, United States, 94546
Eden Hospital Medical Center
Castro Valley, California, United States, 94546
East Bay Radiation Oncology Center
Castro Valley, California, United States, 94546
John Muir Medical Center-Concord Campus
Concord, California, United States, 94520
Northbay Cancer Center
Fairfield, California, United States, 94533
Valley Medical Oncology Consultants-Fremont
Fremont, California, United States, 94538
Kaiser Permanente, Fremont
Fremont, California, United States, 94538
Cancer Care Associates of Fresno Medical Group Inc
Fresno, California, United States, 93720
Saint Jude Medical Center
Fullerton, California, United States, 92835
Kaiser Permanente, Hayward
Hayward, California, United States, 94545
Loma Linda University Medical Center
Loma Linda, California, United States, 92354
Long Beach Memorial Medical Center-Todd Cancer Institute
Long Beach, California, United States, 90806
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, United States, 90027
Kaiser Permanente Medical Care Program - Los Angeles Medical Center &amp; Sunset Hospital
Los Angeles, California, United States, 90027
Jonsson Comprehensive Cancer Center
Los Angeles, California, United States, 90095
Contra Costa Regional Medical Center
Martinez, California, United States, 94553-3156
El Camino Hospital
Mountain View, California, United States, 94040
Bay Area Tumor Institute CCOP
Oakland, California, United States, 94609
Highland General Hospital
Oakland, California, United States, 94602
Tom K Lee Inc
Oakland, California, United States, 94609
Bay Area Breast Surgeons Inc
Oakland, California, United States, 94609
Kaiser Permanente-Oakland
Oakland, California, United States, 94611
Alta Bates Summit Medical Center - Summit Campus
Oakland, California, United States, 94609
Larry G Strieff MD Medical Corporation
Oakland, California, United States, 94609
University of California Medical Center At Irvine-Orange Campus
Orange, California, United States, 92868
Valley Medical Oncology Consultants
Pleasanton, California, United States, 94588
Valley Care Health System - Pleasanton
Pleasanton, California, United States, 94588
Kaiser Permanente-Redwood City
Redwood City, California, United States, 94063
Kaiser Permanente-Richmond
Richmond, California, United States, 94801
Kaiser Permanente-Roseville
Roseville, California, United States, 95661
Kaiser Permanente-South Sacramento
Sacramento, California, United States, 95823
Kaiser Permanente - Sacramento
Sacramento, California, United States, 95825
University of California at Davis Cancer Center
Sacramento, California, United States, 95817
Kaiser Permanente
San Diego, California, United States, 92120
UCSF-Mount Zion
San Francisco, California, United States, 94115
Kaiser Permanente-San Francisco
San Francisco, California, United States, 94115
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, United States, 95119
Doctors Medical Center- JC Robinson Regional Cancer Center
San Pablo, California, United States, 94806
Kaiser Permanente-San Rafael
San Rafael, California, United States, 94903
Santa Barbara Hematology Oncology Group Inc-Santa Barbara
Santa Barbara, California, United States, 93105
Cancer Center of Santa Barbara
Santa Barbara, California, United States, 93105
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, United States, 95051
Kaiser Permanente-Santa Rosa
Santa Rosa, California, United States, 95403
Kaiser Permanente-South San Francisco
South San Francisco, California, United States, 94080
Stanford University Hospitals and Clinics
Stanford, California, United States, 94305
Kaiser Permanente-Stockton
Stockton, California, United States, 95210
Kaiser Permanente-Vallejo
Vallejo, California, United States, 94589
Kaiser Permanente-Walnut Creek
Walnut Creek, California, United States, 94596
John Muir Medical Center
Walnut Creek, California, United States, 94598
United States, Colorado
Colorado Gynecologic Oncology Group
Aurora, Colorado, United States, 80010
The Medical Center of Aurora
Aurora, Colorado, United States, 80012
Boulder Community Hospital
Boulder, Colorado, United States, 80301
Memorial Hospital Colorado Springs
Colorado Springs, Colorado, United States, 80909
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado, United States, 80907
Colorado Cancer Research Program CCOP
Denver, Colorado, United States, 80224-2522
Exempla Saint Joseph Hospital
Denver, Colorado, United States, 80218
Porter Adventist Hospital
Denver, Colorado, United States, 80210
Rose Medical Center
Denver, Colorado, United States, 80220
Presbyterian - Saint Lukes Medical Center - Health One
Denver, Colorado, United States, 80218
Rocky Mountain Gynecologic Oncology PC
Englewood, Colorado, United States, 80110
Swedish Medical Center
Englewood, Colorado, United States, 80113
Front Range Cancer Specialists
Fort Collins, Colorado, United States, 80528
Poudre Valley Hospital
Fort Collins, Colorado, United States, 80524
Saint Mary's Hospital and Regional Medical Center
Grand Junction, Colorado, United States, 81502
North Colorado Medical Center
Greeley, Colorado, United States, 80631
Saint Anthony Hospital
Lakewood, Colorado, United States, 80228
Sky Ridge Medical Center
Lone Tree, Colorado, United States, 80124
Longmont United Hospital
Longmont, Colorado, United States, 80501
McKee Medical Center
Loveland, Colorado, United States, 80539
Saint Mary Corwin Medical Center
Pueblo, Colorado, United States, 81004
North Suburban Medical Center
Thornton, Colorado, United States, 80229
Exempla Lutheran Medical Center
Wheat Ridge, Colorado, United States, 80033
United States, Connecticut
Hartford Hospital
Hartford, Connecticut, United States, 06102
Saint Francis Hospital and Medical Center
Hartford, Connecticut, United States, 06105
Manchester Memorial Hospital
Manchester, Connecticut, United States, 06040
The Hospital of Central Connecticut
New Britain, Connecticut, United States, 06050
Yale University
New Haven, Connecticut, United States, 06520
Norwalk Hospital
Norwalk, Connecticut, United States, 06856
Stamford Hospital/Bennett Cancer Center
Stamford, Connecticut, United States, 06904
United States, Delaware
Beebe Medical Center
Lewes, Delaware, United States, 19958
Christiana Care Health System-Christiana Hospital
Newark, Delaware, United States, 19718
Christiana Gynecologic Oncology LLC
Newark, Delaware, United States, 19713
United States, District of Columbia
Washington Hospital Center
Washington, District of Columbia, United States, 20010
United States, Florida
Morton Plant Hospital
Clearwater, Florida, United States, 33756
Holy Cross Hospital
Fort Lauderdale, Florida, United States, 33308
Florida Gynecologic Oncology
Fort Myers, Florida, United States, 33905
Lee Memorial Health System
Fort Myers, Florida, United States, 33901
Saint Vincent's Medical Center
Jacksonville, Florida, United States, 32204
Mayo Clinic in Florida
Jacksonville, Florida, United States, 32224-9980
Jupiter Medical Center
Jupiter, Florida, United States, 33458
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, United States, 33136
Mount Sinai Medical Center CCOP
Miami Beach, Florida, United States, 33140
Florida Hospital
Orlando, Florida, United States, 32803
UF Cancer Center at Orlando Health
Orlando, Florida, United States, 32806
Bayfront Outpatient Health Clinic
Saint Petersburg, Florida, United States, 33701
Sarasota Memorial Hospital
Sarasota, Florida, United States, 34239
Florida Cancer Specialists-West Palm Beach
West Palm Beach, Florida, United States, 33401
United States, Georgia
Phoebe Putney Memorial Hospital
Albany, Georgia, United States, 31701
Emory University/Winship Cancer Institute
Atlanta, Georgia, United States, 30322
Grady Health System
Atlanta, Georgia, United States, 30303
Georgia Regents University
Augusta, Georgia, United States, 30912
Northeast Georgia Medical Center
Gainesville, Georgia, United States, 30501
Central Georgia Gynecologic Oncology
Macon, Georgia, United States, 31201
Memorial Health University Medical Center
Savannah, Georgia, United States, 31403
United States, Hawaii
Pali Momi Medical Center
Aiea, Hawaii, United States, 96701
Hawaii Minority Based CCOP
Honolulu, Hawaii, United States, 96813
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, United States, 96826
Oncare Hawaii Inc-Kuakini
Honolulu, Hawaii, United States, 96817
Tripler Army Medical Center
Honolulu, Hawaii, United States, 96859
Queen's Medical Center
Honolulu, Hawaii, United States, 96813
University of Hawaii
Honolulu, Hawaii, United States, 96813
The Cancer Center of Hawaii-Liliha
Honolulu, Hawaii, United States, 96817
Oncare Hawaii Inc-POB II
Honolulu, Hawaii, United States, 96813
Straub Clinic and Hospital
Honolulu, Hawaii, United States, 96813
Pacific Cancer Institute of Maui
Wailuku, Hawaii, United States, 96793
Maui Memorial Medical Center
Wailuku, Hawaii, United States, 96793
United States, Idaho
Saint Luke's Mountain States Tumor Institute
Boise, Idaho, United States, 83712
United States, Illinois
Saint Anthony's Health
Alton, Illinois, United States, 62002
Northwest Community Hospital
Arlington Heights, Illinois, United States, 60005
Rush - Copley Medical Center
Aurora, Illinois, United States, 60504
Saint Joseph Medical Center
Bloomington, Illinois, United States, 61701
Graham Hospital Association
Canton, Illinois, United States, 61520
Memorial Hospital
Carthage, Illinois, United States, 62321
Mount Sinai Hospital Medical Center
Chicago, Illinois, United States, 60608
Resurrection Healthcare
Chicago, Illinois, United States, 60631
Rush University Medical Center
Chicago, Illinois, United States, 60612
Northwestern University
Chicago, Illinois, United States, 60611
Swedish Covenant Hospital
Chicago, Illinois, United States, 60625
University of Illinois
Chicago, Illinois, United States, 60612
University of Chicago
Chicago, Illinois, United States, 60637
Weiss Memorial Hospital
Chicago, Illinois, United States, 60640
Decatur Memorial Hospital
Decatur, Illinois, United States, 62526
Elmhurst Memorial Hospital
Elmhurst, Illinois, United States, 60126
Eureka Hospital
Eureka, Illinois, United States, 61530
NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois, United States, 60201
Saint Francis Hospital
Evanston, Illinois, United States, 60202
Galesburg Cottage Hospital
Galesburg, Illinois, United States, 61401
Illinois CancerCare Galesburg
Galesburg, Illinois, United States, 61401
Ingalls Memorial Hospital
Harvey, Illinois, United States, 60426
Mason District Hospital
Havana, Illinois, United States, 62644
Hopedale Medical Complex - Hospital
Hopedale, Illinois, United States, 61747
Joliet Oncology-Hematology Associates Limited
Joliet, Illinois, United States, 60435
Kewanee Hospital
Kewanee, Illinois, United States, 61443
Mcdonough District Hospital
Macomb, Illinois, United States, 61455
Loyola University Medical Center
Maywood, Illinois, United States, 60153
Stoffel, Thomas J MD (UIA Investigator)
Moline, Illinois, United States, 61265
Sharis, Christine M MD (UIA Investigator)
Moline, Illinois, United States, 61265
Porubcin, Michael MD (UIA Investigator)
Moline, Illinois, United States, 61265
Garneau, Stewart C MD (UIA Investigator)
Moline, Illinois, United States, 61265
Good Samaritan Regional Health Center
Mount Vernon, Illinois, United States, 62864
Bromenn Regional Medical Center
Normal, Illinois, United States, 61761
Community Cancer Center Foundation
Normal, Illinois, United States, 61761
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, United States, 61350
Ottawa Regional Hospital and Healthcare Center
Ottawa, Illinois, United States, 61350
Chicago Gynecologic Oncology SC
Palatine, Illinois, United States, 60067
Advocate Lutheran General Hospital.
Park Ridge, Illinois, United States, 60068
Pekin Hospital
Pekin, Illinois, United States, 61554
Pekin Cancer Treatment Center
Pekin, Illinois, United States, 61554
OSF Saint Francis Medical Center
Peoria, Illinois, United States, 61637
Proctor Hospital
Peoria, Illinois, United States, 61614
Illinois CancerCare-Peoria
Peoria, Illinois, United States, 61615
Illinois Oncology Research Association CCOP
Peoria, Illinois, United States, 61615
Methodist Medical Center of Illinois
Peoria, Illinois, United States, 61603
Illinois Valley Hospital
Peru, Illinois, United States, 61354
Perry Memorial Hospital
Princeton, Illinois, United States, 61356
Saint Anthony Medical Center
Rockford, Illinois, United States, 61108
Saint Margaret's Hospital
Spring Valley, Illinois, United States, 61362
Memorial Medical Center
Springfield, Illinois, United States, 62781-0001
Carle Cancer Center
Urbana, Illinois, United States, 61801
Carle Clinic-Urbana Main
Urbana, Illinois, United States, 61801
United States, Indiana
Saint Francis Hospital and Health Centers
Beech Grove, Indiana, United States, 46107
Elkhart General Hospital
Elkhart, Indiana, United States, 46515
Fort Wayne Medical Oncology and Hematology Inc-Parkview
Fort Wayne, Indiana, United States, 46845
Saint Vincent Hospital and Health Services
Indianapolis, Indiana, United States, 46260
Indiana University Medical Center
Indianapolis, Indiana, United States, 46202
Community Howard Regional Health
Kokomo, Indiana, United States, 46904
IU Health La Porte Hospital
La Porte, Indiana, United States, 46350
Franciscan Saint Anthony Health-Michigan City
Michigan City, Indiana, United States, 46360
Saint Joseph Regional Medical Center-Mishawaka
Mishawaka, Indiana, United States, 46545-1470
The Community Hospital
Munster, Indiana, United States, 46321
Reid Hospital and Health Care Services
Richmond, Indiana, United States, 47374
Memorial Hospital of South Bend
South Bend, Indiana, United States, 46601
South Bend Clinic
South Bend, Indiana, United States, 46617
Northern Indiana Cancer Research Consortium
South Bend, Indiana, United States, 46628
United States, Iowa
McFarland Clinic PC-William R Bliss Cancer Center
Ames, Iowa, United States, 50010
Constantinou, Costas L MD (UIA Investigator)
Bettendorf, Iowa, United States, 52722
Oncology Associates at Mercy Medical Center
Cedar Rapids, Iowa, United States, 52403
Mercy Hospital
Cedar Rapids, Iowa, United States, 52403
Cedar Rapids Oncology Association
Cedar Rapids, Iowa, United States, 52403
Medical Oncology and Hematology Associates-West Des Moines
Clive, Iowa, United States, 50325
Genesis Medical Center - East Campus
Davenport, Iowa, United States, 52803
Genesis Medical Center - West Campus
Davenport, Iowa, United States, 52804
Iowa Oncology Research Association CCOP
Des Moines, Iowa, United States, 50309
Iowa Lutheran Hospital
Des Moines, Iowa, United States, 50316
Medical Oncology and Hematology Associates-Des Moines
Des Moines, Iowa, United States, 50309
Mercy Capitol
Des Moines, Iowa, United States, 50307
Iowa Methodist Medical Center
Des Moines, Iowa, United States, 50309
Medical Oncology and Hematology Associates-Laurel
Des Moines, Iowa, United States, 50314
Mercy Medical Center - Des Moines
Des Moines, Iowa, United States, 50314
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States, 52242
Mercy Medical Center-Sioux City
Sioux City, Iowa, United States, 51104
Saint Luke's Regional Medical Center
Sioux City, Iowa, United States, 51104
Siouxland Hematology Oncology Associates
Sioux City, Iowa, United States, 51101
Siouxland Regional Cancer Center
Sioux City, Iowa, United States, 51101-1733
Cedar Valley Medical Specialists
Waterloo, Iowa, United States, 50701
Covenant Medical Center
Waterloo, Iowa, United States, 50702
United States, Kansas
Cancer Center of Kansas - Chanute
Chanute, Kansas, United States, 66720
Cancer Center of Kansas - Dodge City
Dodge City, Kansas, United States, 67801
Cancer Center of Kansas - El Dorado
El Dorado, Kansas, United States, 67042
Cancer Center of Kansas-Independence
Independence, Kansas, United States, 67301
Providence Medical Center
Kansas City, Kansas, United States, 66112
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160
Cancer Center of Kansas-Kingman
Kingman, Kansas, United States, 67068
Lawrence Memorial Hospital
Lawrence, Kansas, United States, 66044
Cancer Center of Kansas - Newton
Newton, Kansas, United States, 67114
Menorah Medical Center
Overland Park, Kansas, United States, 66209
Radiation Oncology Practice Corporation Southwest
Overland Park, Kansas, United States, 66210
Cancer Center of Kansas - Parsons
Parsons, Kansas, United States, 67357
Cancer Center of Kansas - Pratt
Pratt, Kansas, United States, 67124
Cancer Center of Kansas - Salina
Salina, Kansas, United States, 67401
Shawnee Mission Medical Center
Shawnee Mission, Kansas, United States, 66204
Stormont-Vail Regional Health Center
Topeka, Kansas, United States, 66604
Saint Francis Hospital and Medical Center - Topeka
Topeka, Kansas, United States, 66606
Cancer Center of Kansas - Wellington
Wellington, Kansas, United States, 67152
Cancer Center of Kansas - Main Office
Wichita, Kansas, United States, 67214
Associates In Womens Health
Wichita, Kansas, United States, 67208
Wichita CCOP
Wichita, Kansas, United States, 67214
Via Christi Regional Medical Center
Wichita, Kansas, United States, 67214
Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita, Kansas, United States, 67208
Cancer Center of Kansas - Winfield
Winfield, Kansas, United States, 67156
United States, Kentucky
University of Kentucky
Lexington, Kentucky, United States, 40536
The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky, United States, 40202
Norton Health Care Pavilion - Downtown
Louisville, Kentucky, United States, 40202
United States, Louisiana
Tulane University Health Sciences Center
New Orleans, Louisiana, United States, 70112
Christus Schumpert Saint Mary's Place
Shreveport, Louisiana, United States, 71101
United States, Maine
Eastern Maine Medical Center
Bangor, Maine, United States, 04401
Maine Medical Center-Bramhall Campus
Portland, Maine, United States, 04102
United States, Maryland
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, United States, 21287
Greater Baltimore Medical Center
Baltimore, Maryland, United States, 21204
Franklin Square Hospital Center
Baltimore, Maryland, United States, 21237
The Memorial Hospital at Easton
Easton, Maryland, United States, 21601
Memorial Hospital at Easton - Shore Regional Cancer Center
Easton, Maryland, United States, 21601
Union Hospital of Cecil County
Elkton MD, Maryland, United States, 21921
Associates in Oncology Hematology PC -Kensington
Kensington, Maryland, United States, 20895
Kaiser Permanente - Largo Medical Center
Largo, Maryland, United States, 20774
Kaiser Permanente - Towson Medical Center
Lutherville, Maryland, United States, 21093
Kaiser Permanente - Shady Grove Medical Center
Rockville, Maryland, United States, 20850
Associates In Oncology Hematology PC-Rockville
Rockville, Maryland, United States, 20850
Holy Cross Hospital
Silver Spring, Maryland, United States, 20910
United States, Massachusetts
Berkshire Hematology Oncology PC
Pittsfield, Massachusetts, United States, 01201
Baystate Medical Center
Springfield, Massachusetts, United States, 01199
Commonwealth Hematology Oncology PC-Worcester
Worcester, Massachusetts, United States, 01605
University of Massachusetts Medical School
Worcester, Massachusetts, United States, 01655
United States, Michigan
Bixby Medical Center
Adrian, Michigan, United States, 49221
Hickman Cancer Center
Adrian, Michigan, United States, 49221
Saint Joseph Mercy Hospital
Ann Arbor, Michigan, United States, 48106-0995
Michigan Cancer Research Consortium Community Clinical Oncology Program
Ann Arbor, Michigan, United States, 48106
University of Michigan
Ann Arbor, Michigan, United States, 48109
Bronson Battle Creek
Battle Creek, Michigan, United States, 49017
Spectrum Health Big Rapids Hospital
Big Rapids, Michigan, United States, 49307
Oakwood Hospital
Dearborn, Michigan, United States, 48124
Wayne State University/Karmanos Cancer Institute
Detroit, Michigan, United States, 48201
Saint John Hospital and Medical Center
Detroit, Michigan, United States, 48236
Green Bay Oncology - Escanaba
Escanaba, Michigan, United States, 49431
Hurley Medical Center
Flint, Michigan, United States, 48502
Genesys Regional Medical Center-West Flint Campus
Flint, Michigan, United States, 48532
Gynecologic Oncology of West Michigan PLLC
Grand Rapids, Michigan, United States, 49546
Spectrum Health at Butterworth Campus
Grand Rapids, Michigan, United States, 49503
Grand Rapids Clinical Oncology Program
Grand Rapids, Michigan, United States, 49503
Mercy Health Saint Mary's
Grand Rapids, Michigan, United States, 49503
Spectrum Health-Blodgett Campus
Grand Rapids, Michigan, United States, 49506
Holland Community Hospital
Holland, Michigan, United States, 49423
Green Bay Oncology - Iron Mountain
Iron Mountain, Michigan, United States, 49801
Allegiance Health
Jackson, Michigan, United States, 49201
West Michigan Cancer Center
Kalamazoo, Michigan, United States, 49007
Bronson Methodist Hospital
Kalamazoo, Michigan, United States, 49007
Borgess Medical Center
Kalamazoo, Michigan, United States, 49001
Sparrow Hospital
Lansing, Michigan, United States, 48912
Saint Mary Mercy Hospital
Livonia, Michigan, United States, 48154
Mercy Memorial Hospital
Monroe, Michigan, United States, 48162
Community Cancer Center of Monroe
Monroe, Michigan, United States, 48162
Mercy Health Mercy Campus
Muskegon, Michigan, United States, 49444
Mercy Health Partners-Hackley Campus
Muskegon, Michigan, United States, 49442
Northern Michigan Regional Hospital
Petoskey, Michigan, United States, 49770
Saint Joseph Mercy Oakland
Pontiac, Michigan, United States, 48341-2985
Saint Joseph Mercy Port Huron
Port Huron, Michigan, United States, 48060
William Beaumont Hospital-Royal Oak
Royal Oak, Michigan, United States, 48073
Saint Mary's of Michigan
Saginaw, Michigan, United States, 48601
Providence Hospital
Southfield, Michigan, United States, 48075
Lakeland Hospital
St. Joseph, Michigan, United States, 49085
Munson Medical Center
Traverse City, Michigan, United States, 49684
Saint John Macomb-Oakland Hospital
Warren, Michigan, United States, 48093
Metro Health Hospital
Wyoming, Michigan, United States, 49519
United States, Minnesota
Fairview Ridges Hospital
Burnsville, Minnesota, United States, 55337
Mercy Hospital
Coon Rapids, Minnesota, United States, 55433
Essentia Health Saint Mary's Medical Center
Duluth, Minnesota, United States, 55805
Essentia Health Duluth Clinic CCOP
Duluth, Minnesota, United States, 55805
Miller-Dwan Hospital
Duluth, Minnesota, United States, 55805
Fairview-Southdale Hospital
Edina, Minnesota, United States, 55435
Unity Hospital
Fridley, Minnesota, United States, 55432
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, United States, 55109
Abbott-Northwestern Hospital
Minneapolis, Minnesota, United States, 55407
University of Minnesota Medical Center-Fairview
Minneapolis, Minnesota, United States, 55455
Hubert H Humphrey Cancer Center
Robbinsdale, Minnesota, United States, 55422
North Memorial Medical Health Center
Robbinsdale, Minnesota, United States, 55422
Mayo Clinic
Rochester, Minnesota, United States, 55905
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, United States, 55416
Metro-Minnesota CCOP
Saint Louis Park, Minnesota, United States, 55416
United Hospital
Saint Paul, Minnesota, United States, 55102
Saint Francis Regional Medical Center
Shakopee, Minnesota, United States, 55379
Ridgeview Medical Center
Waconia, Minnesota, United States, 55387
Minnesota Oncology and Hematology PA-Woodbury
Woodbury, Minnesota, United States, 55125
United States, Mississippi
Saint Dominic-Jackson Memorial Hospital
Jackson, Mississippi, United States, 39216
Singing River Hospital
Pascagoula, Mississippi, United States, 39581
United States, Missouri
Southeast Missouri Hospital
Cape Girardeau, Missouri, United States, 63701
Saint Francis Medical Center
Cape Girardeau, Missouri, United States, 63703
University of Missouri - Ellis Fischel
Columbia, Missouri, United States, 65212
Centerpoint Medical Center LLC
Independence, Missouri, United States, 64057
Capital Regional Medical Center
Jefferson City, Missouri, United States, 65101
Saint Luke's Hospital of Kansas City
Kansas City, Missouri, United States, 64111
North Kansas City Hospital
Kansas City, Missouri, United States, 64116
Radiation Oncology Practice Corporation - North
Kansas City, Missouri, United States, 64154
Radiation Oncology Practice Corporation South
Kansas City, Missouri, United States, 64114
Research Medical Center
Kansas City, Missouri, United States, 64132
Saint Luke's Cancer Institute
Kansas City, Missouri, United States, 64111
Truman Medical Center
Kansas City, Missouri, United States, 64108
Saint Joseph Health Center
Kansas City, Missouri, United States, 64114
Liberty Hospital
Liberty, Missouri, United States, 64068
Heartland Regional Medical Center
Saint Joseph, Missouri, United States, 64506
Center for Cancer Care and Research
Saint Louis, Missouri, United States, 63141
Saint Louis Cancer and Breast Institute-South City
Saint Louis, Missouri, United States, 63109
Saint Louis University Hospital
Saint Louis, Missouri, United States, 63110
Saint John's Mercy Medical Center
Saint Louis, Missouri, United States, 63141
Missouri Baptist Medical Center
Saint Louis, Missouri, United States, 63131
Saint Louis-Cape Girardeau CCOP
Saint Louis, Missouri, United States, 63141
Washington University School of Medicine
Saint Louis, Missouri, United States, 63110
Mercy Hospital Springfield
Springfield, Missouri, United States, 65804
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield
Springfield, Missouri, United States, 65804
CoxHealth South Hospital
Springfield, Missouri, United States, 65807
United States, Montana
Deaconess Medical Center
Billings, Montana, United States, 59107
Hematology-Oncology Centers of the Northern Rockies PC
Billings, Montana, United States, 59102
Billings Clinic
Billings, Montana, United States, 59107-7000
Montana Cancer Consortium CCOP
Billings, Montana, United States, 59101
Saint Vincent Healthcare
Billings, Montana, United States, 59101
Northern Rockies Radiation Oncology Center
Billings, Montana, United States, 59101
Bozeman Deaconess Hospital
Bozeman, Montana, United States, 59715
Bozeman Deaconess Cancer Center
Bozeman, Montana, United States, 59715
Saint James Community Hospital and Cancer Treatment Center
Butte, Montana, United States, 59701
Great Falls Clinic
Great Falls, Montana, United States, 59405
Big Sky Oncology
Great Falls, Montana, United States, 59405
Benefis Healthcare- Sletten Cancer Institute
Great Falls, Montana, United States, 59405
Berdeaux, Donald MD (UIA Investigator)
Great Falls, Montana, United States, 59405
Northern Montana Hospital
Havre, Montana, United States, 59501
Saint Peter's Community Hospital
Helena, Montana, United States, 59601
Kalispell Regional Medical Center
Kalispell, Montana, United States, 59901
Glacier Oncology PLLC
Kalispell, Montana, United States, 59901
Kalispell Medical Oncology
Kalispell, Montana, United States, 59901
Montana Cancer Specialists
Missoula, Montana, United States, 59802
Saint Patrick Hospital - Community Hospital
Missoula, Montana, United States, 59802
Community Medical Hospital
Missoula, Montana, United States, 59801
Guardian Oncology and Center for Wellness
Missoula, Montana, United States, 59804
United States, Nebraska
Nebraska Cancer Research Center
Lincoln, Nebraska, United States, 68510
Alegent Health Immanuel Medical Center
Omaha, Nebraska, United States, 68122
Creighton University Medical Center
Omaha, Nebraska, United States, 68131
Nebraska Methodist Hospital
Omaha, Nebraska, United States, 68114
Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska, United States, 68124
Missouri Valley Cancer Consortium CCOP
Omaha, Nebraska, United States, 68106
University of Nebraska Medical Center
Omaha, Nebraska, United States, 68198
United States, Nevada
Center of Hope at Renown Medical Center
Reno, Nevada, United States, 89502
Renown Regional Medical Center
Reno, Nevada, United States, 89502
Saint Mary's Regional Medical Center
Reno, Nevada, United States, 89503
United States, New Hampshire
Exeter Hospital
Exeter, New Hampshire, United States, 03833
Cheshire Medical Center-Dartmouth-Hitchcock Keene
Keene, New Hampshire, United States, 03431
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756
Frisbie Hospital
Rochester, New Hampshire, United States, 03867
United States, New Jersey
Ocean Medical Center
Brick, New Jersey, United States, 08724
Cooper Hospital University Medical Center
Camden, New Jersey, United States, 08103
Northern New Jersey CCOP
Hackensack, New Jersey, United States, 07601
Hackensack University Medical CCOP
Hackensack, New Jersey, United States, 07601
Hackensack University Medical Center
Hackensack, New Jersey, United States, 07601
Monmouth Medical Center
Long Branch, New Jersey, United States, 07740
Morristown Memorial Hospital
Morristown, New Jersey, United States, 07962
Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County
Mount Holly, New Jersey, United States, 08060
Jersey Shore Medical Center
Neptune, New Jersey, United States, 07753
UMDNJ - New Jersey Medical School
Newark, New Jersey, United States, 07103
Riverview Medical Center/Booker Cancer Center
Red Bank, New Jersey, United States, 07701
Overlook Hospital
Summit, New Jersey, United States, 07902
Community Medical Center
Toms River, New Jersey, United States, 08755
Virtua West Jersey Hospital Voorhees
Voorhees, New Jersey, United States, 08043
United States, New Mexico
Southwest Gynecologic Oncology Associates Inc
Albuquerque, New Mexico, United States, 87106
University of New Mexico Cancer Center
Albuquerque, New Mexico, United States, 87106
United States, New York
Women's Cancer Care Associates LLC
Albany, New York, United States, 12208
Island Gynecologic Oncology
Brightwaters, New York, United States, 11718
State University of New York Downstate Medical Center
Brooklyn, New York, United States, 11203
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Queens Hospital Center
Jamaica, New York, United States, 11432
North Shore University Hospital
Manhasset, New York, United States, 11030
Orange Regional Medical Center
Middletown, New York, United States, 10940
North Shore-LIJ Health System/Center for Advanced Medicine
New Hyde Park, New York, United States, 11040
Long Island Jewish Medical Center
New Hyde Park, New York, United States, 11040
Mount Sinai Medical Center
New York, New York, United States, 10029
New York University Langone Medical Center
New York, New York, United States, 10016
Columbia University Medical Center
New York, New York, United States, 10032
Memorial Sloan-Kettering Cancer Center
New York, New York, United States, 10065
Stony Brook University Medical Center
Stony Brook, New York, United States, 11794
Saint Joseph's Hospital Health Center
Syracuse, New York, United States, 13203
State University of New York Upstate Medical University
Syracuse, New York, United States, 13210
Good Samaritan Hospital Medical Center
West Islip, New York, United States, 11795
United States, North Carolina
Randolph Hospital
Asheboro, North Carolina, United States, 27203
Hope Women's Cancer Centers-Asheville
Asheville, North Carolina, United States, 28816
Cone Health Alamance Regional Medical Center
Burlington, North Carolina, United States, 27216
University of North Carolina
Chapel Hill, North Carolina, United States, 27599
Carolinas Medical Center
Charlotte, North Carolina, United States, 28203
Novant Health Presbyterian Medical Center
Charlotte, North Carolina, United States, 28204
Duke University Medical Center
Durham, North Carolina, United States, 27710
Wayne Radiation Oncology
Goldsboro, North Carolina, United States, 27534
Wayne Memorial Hospital
Goldsboro, North Carolina, United States, 27534
Cone Health Cancer Center
Greensboro, North Carolina, United States, 27403
Gynecologic Oncology Network
Greenville, North Carolina, United States, 27834
Kinston Medical Specialists PA
Kinston, North Carolina, United States, 28501
FirstHealth of the Carolinas-Moore Regional Hosiptal
Pinehurst, North Carolina, United States, 28374
Annie Penn Memorial Hospital
Reidsville, North Carolina, United States, 27320
Rutherford Hospital
Rutherfordton, North Carolina, United States, 28139
New Hanover Regional Medical Center
Wilmington, North Carolina, United States, 28401
Wilson Medical Center
Wilson, North Carolina, United States, 27893
Novant Health Oncology Specialists
Winston-Salem, North Carolina, United States, 27103
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States, 27157
United States, North Dakota
Sanford Bismarck Medical Center
Bismarck, North Dakota, United States, 58501
Bismarck Cancer Center
Bismarck, North Dakota, United States, 58501
Mid Dakota Clinic
Bismarck, North Dakota, United States, 58501
Saint Alexius Medical Center
Bismarck, North Dakota, United States, 58501
Altru Cancer Center
Grand Forks, North Dakota, United States, 58201
United States, Ohio
Akron General Medical Center
Akron, Ohio, United States, 44307
Summa Akron City Hospital/Cooper Cancer Center
Akron, Ohio, United States, 44304
Toledo Clinic Cancer Centers-Bowling Green
Bowling Green, Ohio, United States, 43402
Aultman Health Foundation
Canton, Ohio, United States, 44710
University of Cincinnati
Cincinnati, Ohio, United States, 45267
Case Western Reserve University
Cleveland, Ohio, United States, 44106
Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland, Ohio, United States, 44111
Cleveland Clinic Foundation
Cleveland, Ohio, United States, 44195
MetroHealth Medical Center
Cleveland, Ohio, United States, 44109
North Coast Cancer Care-Clyde
Clyde, Ohio, United States, 43410
Riverside Methodist Hospital
Columbus, Ohio, United States, 43214
Mount Carmel Health Center West
Columbus, Ohio, United States, 43222
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center
Columbus, Ohio, United States, 43210
Dayton CCOP
Dayton, Ohio, United States, 45420
Good Samaritan Hospital - Dayton
Dayton, Ohio, United States, 45406
Grandview Hospital
Dayton, Ohio, United States, 45405
Veteran Affairs Medical Center
Dayton, Ohio, United States, 45428
Samaritan North Health Center
Dayton, Ohio, United States, 45415
Hematology Oncology Center Incorporated
Elyria, Ohio, United States, 44035
Blanchard Valley Hospital
Findlay, Ohio, United States, 45840
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio, United States, 45005-1066
Fremont Memorial Hospital
Fremont, Ohio, United States, 43420
Wayne Hospital
Greenville, Ohio, United States, 45331
Kettering Medical Center
Kettering, Ohio, United States, 45429
Lima Memorial Hospital
Lima, Ohio, United States, 45804
Toledo Clinic Cancer Centers-Maumee
Maumee, Ohio, United States, 43537
Saint Luke's Hospital
Maumee, Ohio, United States, 43537
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Maumee, Ohio, United States, 43537
Hillcrest Hospital Cancer Center
Mayfield Heights, Ohio, United States, 44124
Lake University Ireland Cancer Center
Mentor, Ohio, United States, 44060
Toledo Clinic Cancer Centers-Oregon
Oregon, Ohio, United States, 43616
Saint Charles Hospital
Oregon, Ohio, United States, 43616
North Coast Cancer Care
Sandusky, Ohio, United States, 44870
Firelands Regional Medical Center
Sandusky, Ohio, United States, 44870
Flower Hospital
Sylvania, Ohio, United States, 43560
Mercy Hospital of Tiffin
Tiffin, Ohio, United States, 44883
Toledo Community Hospital Oncology Program CCOP
Toledo, Ohio, United States, 43617
Mercy Saint Anne Hospital
Toledo, Ohio, United States, 43623
Toledo Clinic Cancer Centers-Toledo
Toledo, Ohio, United States, 43623
The Toledo Hospital/Toledo Children's Hospital
Toledo, Ohio, United States, 43606
Saint Vincent Mercy Medical Center
Toledo, Ohio, United States, 43608
University of Toledo
Toledo, Ohio, United States, 43614
Upper Valley Medical Center
Troy, Ohio, United States, 45373
Fulton County Health Center
Wauseon, Ohio, United States, 43567
Clinton Memorial Hospital
Wilmington, Ohio, United States, 45177
Greene Memorial Hospital
Xenia, Ohio, United States, 45385
United States, Oklahoma
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States, 73104
Tulsa Cancer Institute
Tulsa, Oklahoma, United States, 74146
Cancer Care Associates-Midtown
Tulsa, Oklahoma, United States, 74104
United States, Oregon
Bay Area Hospital
Coos Bay, Oregon, United States, 97420
Compass Oncology Rose Quarter
Portland, Oregon, United States, 97227
Kaiser Permanente
Portland, Oregon, United States, 97227
Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon, United States, 97210
Oregon Health and Science University
Portland, Oregon, United States, 97239
United States, Pennsylvania
Abington Memorial Hospital
Abington, Pennsylvania, United States, 19001
Lehigh Valley Hospital
Allentown, Pennsylvania, United States, 18105
Bryn Mawr Hospital
Bryn Mawr, Pennsylvania, United States, 19010
Ephrata Cancer Center
Ephrata, Pennsylvania, United States, 17522
Penn State Milton S Hershey Medical Center
Hershey, Pennsylvania, United States, 17033-0850
Lancaster General Hospital
Lancaster, Pennsylvania, United States, 17604
Riddle Hospital
Media, Pennsylvania, United States, 19063
Paoli Memorial Hospital
Paoli, Pennsylvania, United States, 19301
University of Pennsylvania/Abramson Cancer Center
Philadelphia, Pennsylvania, United States, 19104
Fox Chase Cancer Center
Philadelphia, Pennsylvania, United States, 19111
Chestnut Hill Health System
Philadelphia, Pennsylvania, United States, 19118
Pennsylvania Hospital
Philadelphia, Pennsylvania, United States, 19107
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States, 19107
Western Pennsylvania Hospital
Pittsburgh, Pennsylvania, United States, 15224-1791
Magee-Womens Hospital of UPMC
Pittsburgh, Pennsylvania, United States, 15213
Mercy Hospital
Scranton, Pennsylvania, United States, 18501
Hematology and Oncology Associates of North East Pennsylvania
Scranton, Pennsylvania, United States, 18508
Scranton Hematology Oncology
Scranton, Pennsylvania, United States, 18510
Reading Hospital
West Reading, Pennsylvania, United States, 19611
Mainline Health CCOP
Wynnewood, Pennsylvania, United States, 19096
Lankenau Hospital
Wynnewood, Pennsylvania, United States, 19096
WellSpan Health-York Cancer Center
York, Pennsylvania, United States, 17403
WellSpan Health-York Hospital
York, Pennsylvania, United States, 17405
United States, Rhode Island
Women and Infants Hospital
Providence, Rhode Island, United States, 02905
United States, South Carolina
AnMed Health Hospital
Anderson, South Carolina, United States, 29621
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Greenville Health System Cancer Institute/Greenville CCOP
Greenville, South Carolina, United States, 29615
Upstate Carolina CCOP
Spartanburg, South Carolina, United States, 29303
United States, South Dakota
Black Hills Obstetrics and Gynecology
Rapid City, South Dakota, United States, 57701
Sanford Cancer Center-Oncology Clinic
Sioux Falls, South Dakota, United States, 57104
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, United States, 57117-5134
United States, Tennessee
Chattanooga Gynecological Oncology
Chattanooga, Tennessee, United States, 37403
Chattanooga's Program in Women's Oncology
Chattanooga, Tennessee, United States, 37403
East Tennessee State University
Johnson City, Tennessee, United States, 37614-0054
Knoxville Gynecologic Cancer Specialists PC
Knoxville, Tennessee, United States, 37920
University of Tennesee Health Science Center
Memphis, Tennessee, United States, 38103
Meharry Medical College
Nashville, Tennessee, United States, 37208-3599
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, United States, 37232
United States, Texas
The Don and Sybil Harrington Cancer Center
Amarillo, Texas, United States, 79106
Brooke Army Medical Center
Fort Sam Houston, Texas, United States, 78234
University of Texas Medical Branch at Galveston
Galveston, Texas, United States, 77555-0565
M D Anderson Cancer Center
Houston, Texas, United States, 77030
Texas Tech University Health Sciences Center
Lubbock, Texas, United States, 79430
Scott and White Memorial Hospital
Temple, Texas, United States, 76508
United States, Utah
American Fork Hospital
American Fork, Utah, United States, 84003
Sandra L Maxwell Cancer Center
Cedar City, Utah, United States, 84720
Logan Regional Hospital
Logan, Utah, United States, 84321
Intermountain Medical Center
Murray, Utah, United States, 84157
Cottonwood Hospital Medical Center
Murray, Utah, United States, 84107
McKay-Dee Hospital Center
Ogden, Utah, United States, 84403
Utah Valley Regional Medical Center
Provo, Utah, United States, 84604-3337
Dixie Medical Center Regional Cancer Center
Saint George, Utah, United States, 84770
LDS Hospital
Salt Lake City, Utah, United States, 84143
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, United States, 84112
Utah Cancer Specialists-Salt Lake City
Salt Lake City, Utah, United States, 84106
Intermountain Health Care
Salt Lake City, Utah, United States, 84103
United States, Vermont
Fletcher Allen Health Care-Medical Center
Burlington, Vermont, United States, 05401
United States, Virginia
Northern Virginia Pelvic Surgery Associates
Annandale, Virginia, United States, 22003
University of Virginia
Charlottesville, Virginia, United States, 22908
Danville Regional Medical Center
Danville, Virginia, United States, 24541
Kaiser Permanente - Fair Oaks Medical Center
Fairfax, Virginia, United States, 22033
Fredericksburg Oncology Inc
Fredericksburg, Virginia, United States, 22401
Rappahannock General Hospital
Kilmarnock, Virginia, United States, 22482
Bon Secours Mary Immaculate Hospital
Newport News, Virginia, United States, 23602
Virginia Oncology Associates - Lake Wright
Norfolk, Virginia, United States, 23502
Virginia Commonwealth University
Richmond, Virginia, United States, 23298
Carilion Clinic Gynecological Oncology
Roanoke, Virginia, United States, 24016
United States, Washington
Auburn Regional Medical Center
Auburn, Washington, United States, 98001
Providence Centralia Hospital
Centralia, Washington, United States, 98531
Saint Francis Hospital
Federal Way, Washington, United States, 98003
Capital Medical Center
Olympia, Washington, United States, 98507
Providence - Saint Peter Hospital
Olympia, Washington, United States, 98506-5166
Good Samaritan Community Hospital
Puyallup, Washington, United States, 98372
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
Seattle, Washington, United States, 98109
University of Washington Medical Center
Seattle, Washington, United States, 98195
Virginia Mason CCOP
Seattle, Washington, United States, 98101
Multicare Health System
Tacoma, Washington, United States, 98415
Allenmore Hospital
Tacoma, Washington, United States, 98405
Northwest CCOP
Tacoma, Washington, United States, 98405
Northwest Medical Specialties PLLC
Tacoma, Washington, United States, 98405
Saint Joseph Medical Center
Tacoma, Washington, United States, 98405
Tacoma General Hospital
Tacoma, Washington, United States, 98405
Saint Clare Hospital
Tacoma, Washington, United States, 98499
Madigan Army Medical Center
Tacoma, Washington, United States, 98431
United States, Wisconsin
Marshfield Clinic-Chippewa Center
Chippewa Falls, Wisconsin, United States, 54729
Marshfield Clinic Cancer Center at Sacred Heart
Eau Claire, Wisconsin, United States, 54701
Sacred Heart Hospital
Eau Claire, Wisconsin, United States, 54701
Saint Vincent Hospital
Green Bay, Wisconsin, United States, 54301
Saint Mary's Hospital
Green Bay, Wisconsin, United States, 54303
Green Bay Oncology at Saint Vincent Hospital
Green Bay, Wisconsin, United States, 54301-3526
Aurora BayCare Medical Center
Green Bay, Wisconsin, United States, 54311-6519
Green Bay Oncology Limited at Saint Mary's Hospital
Green Bay, Wisconsin, United States, 54303
Dean Hematology and Oncology Clinic
Madison, Wisconsin, United States, 53717
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States, 53792
Holy Family Memorial Hospital
Manitowoc, Wisconsin, United States, 54221
Bay Area Medical Center
Marinette, Wisconsin, United States, 54143
Saint Joseph's Hospital
Marshfield, Wisconsin, United States, 54449
Marshfield Clinic
Marshfield, Wisconsin, United States, 54449
Froedtert and the Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Medical Consultants Limited
Milwaukee, Wisconsin, United States, 53215
Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin, United States, 54548
Oconomowoc Memorial Hospital-ProHealth Care Inc
Oconomowoc, Wisconsin, United States, 53066-3896
Green Bay Oncology - Oconto Falls
Oconto Falls, Wisconsin, United States, 54154
Marshfield Clinic at James Beck Cancer Center
Rhinelander, Wisconsin, United States, 54501
Marshfield Clinic-Rice Lake Center
Rice Lake, Wisconsin, United States, 54868
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin, United States, 53081
Vince Lombardi Cancer Clinic - Slinger
Slinger, Wisconsin, United States, 53086
Saint Michael's Hospital
Stevens Point, Wisconsin, United States, 54481
Green Bay Oncology - Sturgeon Bay
Sturgeon Bay, Wisconsin, United States, 54235
Waukesha Memorial Hospital - ProHealth Care
Waukesha, Wisconsin, United States, 53188
Aurora West Allis Medical Center
West Allis, Wisconsin, United States, 53227
Marshfield Clinic - Weston Center
Weston, Wisconsin, United States, 54476
Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids, Wisconsin, United States, 54494
United States, Wyoming
Welch Cancer Center
Sheridan, Wyoming, United States, 82801
Canada, Ontario
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada, M4N 3M5
Japan
Tohoku University School of Medicine
Sendai, Aoba-ku, Japan, 980-8574
Kure National Hospital
Kure, Hiroshima, Japan, 737
Iwate Medical University School of Medicine
Morioka, Iwate, Japan, 020-8505
Keio University
Shinjuku-ku, Tokyo, Japan, 160-8582
Kagoshima City Hospital
Kagoshima City, Kagoshima, Japan, 892-8580
National Hospital Organization-Kobe Medical Center
Kobe, Japan, 654-0155
Shikoku Cancer Center
Matsuyama, Japan, 791-0280
Saitama Medical University International Medical Center
Saitama, Japan, 350-1298
National Cancer Center Hospital
Tokyo, Japan, 104 0045
Tottori University
Tottori, Japan, 680-8550
Korea, Republic of
Samsung Medical Center
Seoul, Korea, Korea, Republic of, 135-710
Asan Medical Center
Seoul, Korea, Republic of, 138-736
Yongdong Severence Hospital
Seoul, Korea, Republic of, 135-720
Korea Cancer Center Hospital
Seoul, Korea, Republic of, 139-706
Seoul National University Hospital
Seoul, Korea, Republic of, 110-744
Ajou University Hospital
Suwon, Korea, Republic of, 443-721
Kangnam Sacred Heart Hospital
Youngdungpo-gu, Korea, Republic of, 150-071
Sponsors and Collaborators
Investigators
Principal Investigator: Robert Burger Gynecologic Oncology Group
  More Information

No publications provided by National Cancer Institute (NCI)

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: National Cancer Institute (NCI)
ClinicalTrials.gov Identifier: NCT00262847     History of Changes
Other Study ID Numbers: NCI-2009-00590, NCI-2009-00590, CDR0000455114, GOG-0218, GOG-0218, U10CA027469
Study First Received: December 6, 2005
Results First Received: July 9, 2013
Last Updated: June 18, 2014
Health Authority: United States: Food and Drug Administration

Additional relevant MeSH terms:
Peritoneal Neoplasms
Fallopian Tube Neoplasms
Adenocarcinoma
Neoplasms, Glandular and Epithelial
Ovarian Neoplasms
Cystadenocarcinoma
Carcinoma
Carcinoma, Endometrioid
Cystadenocarcinoma, Serous
Cystadenocarcinoma, Mucinous
Brenner Tumor
Abdominal Neoplasms
Neoplasms by Site
Neoplasms
Digestive System Neoplasms
Digestive System Diseases
Peritoneal Diseases
Genital Neoplasms, Female
Urogenital Neoplasms
Fallopian Tube Diseases
Adnexal Diseases
Genital Diseases, Female
Neoplasms by Histologic Type
Endocrine Gland Neoplasms
Ovarian Diseases
Endocrine System Diseases
Gonadal Disorders
Neoplasms, Cystic, Mucinous, and Serous
Endometrial Neoplasms
Uterine Neoplasms

ClinicalTrials.gov processed this record on September 16, 2014