Carotid Atherosclerotic Plaque Study

The recruitment status of this study is unknown because the information has not been verified recently.

Verified January 2010 by University of Wisconsin, Madison. Recruitment status was Recruiting

First Received on September 13, 2005. Last Updated on January 12, 2010 History of Changes

Sponsor:	University of Wisconsin, Madison
Information provided by:	University of Wisconsin, Madison
ClinicalTrials.gov Identifier:	NCT00214006

Purpose

First, to establish a comparison of the pathophysiology of carotid atherosclerosis and the genetic and environmental variables that cause those plaques to become symptomatic. Second, to differentiate between vulnerable plaque and other types of plaque using ultrasound elastography, MRI data, trans-cranial doppler along with RF analysis of back-scattered ultrasonic echoes.

Condition
Atherosclerosis

Study Type:	Observational
Study Design:	Observational Model: Case-Only Time Perspective: Prospective
Official Title:	Carotid Atherosclerotic Plaque Study

Resource links provided by NLM:

MedlinePlus related topics: Atherosclerosis

U.S. FDA Resources

Further study details as provided by University of Wisconsin, Madison:

Estimated Enrollment:	200
Study Start Date:	November 2001
Estimated Study Completion Date:	December 2010

Detailed Description:

This is a multi-investigator study based on the pathophysiology of carotid atherosclerosis and the variables that cause certain plaques to become symptomatic.Patients enrolled in this study will be those patients undergoing a carotid endarterectomy. This will include both symptomatic and asymptomatic patients, and there are a variety of atherosclerotic risk factors representing this patient population.Patients may or may not have had strokes or transient ischemic attacks (TIAs).Pre-operatively patients will be reviewed for their medical history and atherosclerotic risk factors. Plaque removed during routine carotid endarterectomy will be examined for study purposes.

Eligibility

Ages Eligible for Study:	18 Years to 80 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Patients undergoing carotid endarectomy

Criteria

Inclusion Criteria:

Male and Female patients aged 18-80 presenting for carotid endarterectomy

Exclusion Criteria:

Patients not felt suitable for carotid endarterectomy and those with impaired decision-making capacity

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00214006

Contacts

Contact: Pam Winne

pkw@clinicaltrials.wisc.edu

Locations

United States, Wisconsin
University of Wisconsin	Recruiting
Madison, Wisconsin, United States, 53792
Contact: Pam Winne pkw@clinicaltrials.wisc.edu

Sponsors and Collaborators

University of Wisconsin, Madison

Investigators

Principal Investigator:

Robert J. Dempsey, MD

University of Wisconsin, Madison

More Information

No publications provided

Responsible Party:	Robert J. Dempsey, MD, University of Wisconsin
ClinicalTrials.gov Identifier:	NCT00214006 History of Changes
Other Study ID Numbers:	2008-0053
Study First Received:	September 13, 2005
Last Updated:	January 12, 2010
Health Authority:	United States: Institutional Review Board

Additional relevant MeSH terms:

Atherosclerosis
Plaque, Atherosclerotic
Arteriosclerosis
Arterial Occlusive Diseases

Vascular Diseases
Cardiovascular Diseases
Pathological Conditions, Anatomical

ClinicalTrials.gov processed this record on February 12, 2012