Disease Modifying Genes in Severe Asthma
Gene and protein bank to study disease modifying and susceptibility genes and proteins in urban patients with asthma.
|Study Design:||Observational Model: Case Control|
|Official Title:||Disease Modifying Genes in Severe Asthma|
- To recruit and characterize a cohort of subjects with asthma who reside in a high pollution, high asthma risk neighborhood [ Time Frame: five yeARS ] [ Designated as safety issue: Yes ]
Biospecimen Retention: Samples With DNA
The total amount of blood drawn is approximately 5 tablespoons (75 ml). The blood sample will be processed to isolate "genetic material" (mainly DNA, RNA and protein). This genetic material will be used to try to identify the "genetic factors" or genes that a person inherits that make him or her more likely to develop asthma. The blood is used to test for allergies to weeds, trees, insects and molds (RAST) and a complete blood count.
|Study Start Date:||April 2002|
|Estimated Primary Completion Date:||January 2014 (Final data collection date for primary outcome measure)|
|United States, New York|
|NYU School of Medicine|
|New York, New York, United States, 10016|
|Principal Investigator:||Joan Reibman, MD||NYU School of Medicine|