Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

The recruitment status of this study is unknown because the information has not been verified recently.

Verified September 2005 by University Hospital, Limoges. Recruitment status was Recruiting

First Received on September 14, 2005. Last Updated on March 10, 2006 History of Changes

Sponsor:	University Hospital, Limoges
Information provided by:	University Hospital, Limoges
ClinicalTrials.gov Identifier:	NCT00199628

Purpose

Problems of compatibility between a mother and her child are frequent. The most well-known case can be illustrated by the fetomaternal blood group incompatibility (rhesus factor) which can induce severe anemia of the fetus.

The investigators recently proved that incompatibility between mother and child can concern an organ leading to a tissular alloimmunization. For example, neonatal membranous glomerulonephritis (a kidney disease) can result from this mechanism.

The purpose of this network is to detect and study neonatal diseases induced by tissular fetomaternal alloimmunization. The detection of these diseases will be performed by the mother's serum analysis.

Condition
Glomerulonephritis, Membranous Neonatal Diseases and Abnormalities Hemochromatosis

Study Type:	Observational
Study Design:	Observational Model: Defined Population Time Perspective: Longitudinal Time Perspective: Prospective
Official Title:	Research Network for Neonatal Diseases Induced by Tissular Fetomaternal Alloimmunization

Resource links provided by NLM:

Genetics Home Reference related topics: hemochromatosis

MedlinePlus related topics: Common Infant and Newborn Problems Hemochromatosis Uncommon Infant and Newborn Problems

U.S. FDA Resources

Further study details as provided by University Hospital, Limoges:

Estimated Enrollment:	100
Study Start Date:	September 2005

Eligibility

Genders Eligible for Study:	Female
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Mothers having a child suffering from:

Neonatal membranous glomerulonephritis
Unexplained neonatal tubular defect
Unexplained thrombotic microangiopathy
Neonatal hemochromatosis

Exclusion Criteria:

Any cause explaining the child's disease

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00199628

Contacts

Contact: Vincent Guigonis, MD

+33(0)555 056 358

vincent.guigonis@chu-limoges.fr

Locations

France
Limoges University Hospital	Recruiting
Limoges, France, 87042
Contact: Vincent Guigonis, MD +33(0) 555 056 358 vincent.guigonis@chu-limoges.fr
Principal Investigator: Vincent Guigonis, MD

Sponsors and Collaborators

University Hospital, Limoges

Investigators

Principal Investigator:

Vincent Guigonis, MD

Department of Pediatrics, Limoges University Hospital

More Information

No publications provided

ClinicalTrials.gov Identifier:	NCT00199628 History of Changes
Other Study ID Numbers:	I05001
Study First Received:	September 14, 2005
Last Updated:	March 10, 2006
Health Authority:	France: Ministry of Health

Keywords provided by University Hospital, Limoges:

fetomaternal tissular alloimmunization
Mothers having a child suffering from:
neonatal membranous glomerulonephritis

unexplained neonatal tubular defect
unexplained thrombotic microangiopathy
neonatal hemochromatosis

Additional relevant MeSH terms:

Congenital Abnormalities
Glomerulonephritis
Glomerulonephritis, Membranous
Hemochromatosis
Infant, Newborn, Diseases
Nephritis
Kidney Diseases
Urologic Diseases

Autoimmune Diseases
Immune System Diseases
Metal Metabolism, Inborn Errors
Metabolism, Inborn Errors
Genetic Diseases, Inborn
Iron Overload
Iron Metabolism Disorders
Metabolic Diseases

ClinicalTrials.gov processed this record on February 12, 2012