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Symptomatic, Biomechanical and Radiographic Outcomes in Knee Osteoarthritis Following Gastric Bypass Surgery

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2005 by University Hospitals of Cleveland.
Recruitment status was  Active, not recruiting
Sponsor:
Collaborator:
Elizabeth Severance Prentiss Foundation
Information provided by:
University Hospitals of Cleveland
ClinicalTrials.gov Identifier:
NCT00194051
First received: September 13, 2005
Last updated: October 5, 2006
Last verified: September 2005
History of Changes
  Purpose

Weight is a risk factor for knee osteoarthritis

Knee osteoarthritis is associated with abnormal gait biomechanics

Gait biomechanics are evaluated in gastric bypass patients before and after losing 100 pounds.


Condition Intervention
Obesity
Osteoarthritis
 Procedure: gastric bypass surgery

Study Type: Observational
Study Design: Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Symptomatic, Biomechanical and Radiographic Outcomes in Knee Osteoarthritis Following Gastric Bypass Surgery

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University Hospitals of Cleveland:

Estimated Enrollment: 35
Study Start Date: February 2003
Estimated Study Completion Date: May 2006
Detailed Description:

Weight is a major risk factor for development of knee osteoarthritis, but not hip or ankle arthritis. One possible mechanism for this is the generation of abnormal gait biomechanics secondary to obesity that are conducive to the development of knee osteoarthritis.

We evaluate gait biomechanics, knee symptoms and knee radiographs in 35 obese patients before and after gastric bypass surgery to determine the effect of significant weight loss on gait biomechanics, knee symptoms and knee radiographs.

  Eligibility

Ages Eligible for Study:   35 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

Undergoing gastric bypass surgery At least 35 years old

-

Exclusion Criteria:

Inability to walk unassisted Pain affecting gait in any lower extremity joint

-

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00194051

Locations
United States, Ohio
University Hospitals of Cleveland
Cleveland, Ohio, United States, 44106
Sponsors and Collaborators
University Hospitals of Cleveland
Elizabeth Severance Prentiss Foundation
Investigators
Principal Investigator: Michele M Hooper, MD, MS University Hospitals of Cleveland
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00194051     History of Changes
Other Study ID Numbers: 02-03-10
Study First Received: September 13, 2005
Last Updated: October 5, 2006
Health Authority: United States: Institutional Review Board

Keywords provided by University Hospitals of Cleveland:
obesity
gait biomechanics
knee osteoarthritis

Additional relevant MeSH terms:
Obesity
Osteoarthritis
Osteoarthritis, Knee
Overnutrition
Nutrition Disorders
Overweight
 Body Weight
Signs and Symptoms
Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases

ClinicalTrials.gov processed this record on May 22, 2013