Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer
This study is ongoing, but not recruiting participants.
Sponsor:
Radiation Therapy Oncology Group
Collaborator:
Information provided by:
National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:
NCT00063882
First received: July 8, 2003
Last updated: August 3, 2012
Last verified: February 2012
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Purpose
RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Interstitial brachytherapy uses radioactive material placed directly into or near a tumor to kill tumor cells. Combining interstitial brachytherapy with external-beam radiation therapy may kill more tumor cells. It is not yet known whether interstitial brachytherapy is more effective with or without external-beam radiation therapy in treating prostate cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of interstitial brachytherapy with or without external-beam radiation therapy in treating patients who have prostate cancer.
| Condition | Intervention | Phase |
|---|---|---|
|
Prostate Cancer |
Radiation: iodine I 125 Radiation: palladium Pd 103 Radiation: radiation therapy |
Phase 3 |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Primary Purpose: Treatment |
| Official Title: | A Phase III Study Comparing Combined External Beam Radiation and Transperineal Interstitial Permanent Brachytherapy With Brachytherapy Alone for Selected Patients With Intermediate Risk Prostatic Carcinoma |
Resource links provided by NLM:
Further study details as provided by National Cancer Institute (NCI):
Primary Outcome Measures:
- Freedom from progression [ Designated as safety issue: No ]
Secondary Outcome Measures:
- Biochemical (i.e., prostate-specific antigen) failure for at least 5 years [ Designated as safety issue: No ]
- Biochemical failure by the Phoenix definition [ Designated as safety issue: No ]
- Disease-specific survival [ Designated as safety issue: No ]
- Local progression [ Designated as safety issue: No ]
- Distant metastases [ Designated as safety issue: No ]
- Overall survival [ Designated as safety issue: No ]
- Incidence of "acute" toxicities [ Designated as safety issue: Yes ]
- Time to "late" 3+ toxicities [ Designated as safety issue: Yes ]
- Health-related quality of life as measured by EPIC, EQ5D, and AUA-SI from baseline to 4 months (early) and then at 2 years (late) after initiation of therapy [ Designated as safety issue: No ]
- Feasibility of collecting Medicare data in a large RTOG prostate cancer clinical trial for cost effectiveness and cost utility analysis of combined treatment with interstitial brachytherapy and external beam radiotherapy [ Designated as safety issue: No ]
| Estimated Enrollment: | 586 |
| Study Start Date: | June 2003 |
| Estimated Primary Completion Date: | January 2017 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Experimental: Arm I
Patients undergo external beam radiotherapy 5 days a week for 5 weeks. Within 2-4 weeks of radiotherapy, patients undergo interstitial brachytherapy with iodine I 125 or palladium Pd 103 seeds.
|
Radiation: iodine I 125
Given as interstitial seeds
Radiation: palladium Pd 103
Given as interstitial seeds
Radiation: radiation therapy
Given as external beam radiation therapy over 5 weeks
|
|
Active Comparator: Arm II
Patients undergo interstitial brachytherapy only, as in arm I.
|
Radiation: iodine I 125
Given as interstitial seeds
Radiation: palladium Pd 103
Given as interstitial seeds
|
Detailed Description:
OBJECTIVES:
- Compare the 5-year freedom from progression in patients with intermediate-risk prostate cancer treated with interstitial brachytherapy with or without external beam radiotherapy (EBRT).
- Compare biochemical (i.e., prostate-specific antigen) failure, biochemical failure by the Phoenix definition, disease-specific survival, local progression, and distant metastases in patients treated with these regimens.
- Compare morbidity and quality of life of patients treated with these regimens.
- Determine the feasibility of collecting Medicare data in a large RTOG prostate cancer clinical trial for cost effectiveness and cost utility analysis of combined treatment with interstitial brachytherapy and EBRT.
- Prospectively collect diagnostic biopsy samples from these patients for future biomarker analyses.
OUTLINE: This is a randomized, multicenter study. Patients are stratified according to disease stage (T1c vs T2a or T2b), Gleason score (≤ 6 vs 7), prostate-specific antigen (< 10 ng/mL vs 10-20 ng/mL), and prior neoadjuvant hormonal therapy (yes vs no). Patients are randomized to 1 of 2 treatment arms.
- Arm I: Patients undergo external beam radiotherapy 5 days a week for 5 weeks. Within 2-4 weeks of radiotherapy, patients undergo interstitial brachytherapy with iodine I 125 or palladium Pd 103 seeds.
- Arm II: Patients undergo interstitial brachytherapy only, as in arm I. Quality of life is assessed at baseline, at 4, 12, and 24 months, and then annually for 3 years.
After completion of study treatment, patients are followed at 3-5 weeks, at 4, 6, 9, and 12 months, every 6 months for 4 years, and then annually thereafter.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Male |
| Accepts Healthy Volunteers: | No |
Criteria
DISEASE CHARACTERISTICS:
Histologically confirmed adenocarcinoma of the prostate
- T1c-T2b, N0, M0
Intermediate-risk disease, as defined by 1 of the following:
- Gleason score < 7 AND prostate-specific antigen (PSA) 10-20 ng/mL
- Gleason score 7 AND PSA < 10 ng/mL
- No evidence of distant metastases
- Prostate volume ≤ 60 cc by transrectal ultrasonography
- American Urological Association voiding symptom score no greater than 15 (alpha blockers allowed)
PATIENT CHARACTERISTICS:
Age
- 18 and over
Performance status
- Zubrod 0-1
Life expectancy
- Not specified
Hematopoietic
- Not specified
Hepatic
- Not specified
Renal
- Not specified
Other
- Patients must use effective contraception
- No other malignancy within the past 5 years except basal cell or squamous cell skin cancer or carcinoma in situ at any other site
- No major medical or psychiatric illness that would preclude study therapy
- No hip prosthesis
PRIOR CONCURRENT THERAPY:
Biologic therapy
- Not specified
Chemotherapy
- No prior chemotherapy
Endocrine therapy
Prior neoadjuvant hormonal therapy allowed provided the following are true:
- Therapy was initiated within 2-6 months of study enrollment
- Therapy was no more than 6 months in duration
- Use of 5-alpha reductase inhibitors (e.g., finasteride) is discontinued before registration
- No concurrent hormonal therapy
Radiotherapy
- No prior pelvic radiotherapy
Surgery
- No prior radical surgery for prostate cancer
- No prior transurethral resection of the prostate
- No prior cryosurgery
Other
- No prior transurethral needle ablation of the prostate
- No prior transurethral microwave thermotherapy of the prostate
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00063882
Hide Study Locations
Hide Study LocationsLocations
| United States, Arizona | |
| Arizona Oncology Services Foundation | |
| Phoenix, Arizona, United States, 85013 | |
| United States, California | |
| Auburn Radiation Oncology | |
| Auburn, California, United States, 95603 | |
| Alta Bates Summit Comprehensive Cancer Center | |
| Berkeley, California, United States, 94704 | |
| Peninsula Medical Center | |
| Burlingame, California, United States, 94010 | |
| Radiation Oncology Centers - Cameron Park | |
| Cameron Park, California, United States, 95682 | |
| Mercy Cancer Center at Mercy San Juan Medical Center | |
| Carmichael, California, United States, 95608 | |
| Valley Medical Oncology Consultants - Castro Valley | |
| Castro Valley, California, United States, 94546 | |
| East Bay Radiation Oncology Center | |
| Castro Valley, California, United States, 94546 | |
| Valley Medical Oncology | |
| Fremont, California, United States, 94538 | |
| California Cancer Center - Woodward Park Office | |
| Fresno, California, United States, 93720 | |
| Kaiser Permanente Medical Center - Hayward | |
| Hayward, California, United States, 94545 | |
| Contra Costa Regional Medical Center | |
| Martinez, California, United States, 94553-3156 | |
| El Camino Hospital Cancer Center | |
| Mountain View, California, United States, 94040 | |
| Sutter Health - Western Division Cancer Research Group | |
| Novato, California, United States, 94945 | |
| Kaiser Permanente Medical Center - Oakland | |
| Oakland, California, United States, 94611 | |
| Larry G Strieff MD Medical Corporation | |
| Oakland, California, United States, 94609 | |
| Kaiser Permanente - Division of Research - Oakland | |
| Oakland, California, United States, 94611 | |
| Bay Area Breast Surgeons, Incorporated | |
| Oakland, California, United States, 94609 | |
| Alta Bates Summit Medical Center - Summit Campus | |
| Oakland, California, United States, 94609 | |
| Tom K Lee, Incorporated | |
| Oakland, California, United States, 94609 | |
| CCOP - Bay Area Tumor Institute | |
| Oakland, California, United States, 94609 | |
| Kaiser Permanente Medical Center - Rancho Cordova | |
| Rancho Cordova, California, United States, 95670 | |
| Kaiser Permanente Medical Center - Redwood City | |
| Redwood City, California, United States, 94063 | |
| Kaiser Permanente Medical Center - Richmond | |
| Richmond, California, United States, 94801 | |
| Rohnert Park Cancer Center | |
| Rohnert Park, California, United States, 94928 | |
| Radiation Oncology Center - Roseville | |
| Roseville, California, United States, 95661 | |
| Kaiser Permanente Medical Center - Roseville | |
| Roseville, California, United States, 95661 | |
| Radiological Associates of Sacramento Medical Group, Incorporated | |
| Sacramento, California, United States, 95815 | |
| Kaiser Permanente Medical Center - Sacramento | |
| Sacramento, California, United States, 95825 | |
| South Sacramento Cancer Center | |
| Sacramento, California, United States, 95823 | |
| Mercy General Hospital | |
| Sacramento, California, United States, 95819 | |
| South Sacramento Kaiser-Permanente Medical Center | |
| Sacramento, California, United States, 95823 | |
| UCSF Helen Diller Family Comprehensive Cancer Center | |
| San Francisco, California, United States, 94115 | |
| California Pacific Medical Center - California Campus | |
| San Francisco, California, United States, 94118 | |
| Kaiser Permanente Medical Center - San Francisco Geary Campus | |
| San Francisco, California, United States, 94115 | |
| Kaiser Permanente Medical Center - Santa Teresa | |
| San Jose, California, United States, 95119 | |
| Kaiser Foundation Hospital - San Rafael | |
| San Rafael, California, United States, 94903 | |
| Kaiser Permanente Medical Center - Santa Clara Kiely Campus | |
| Santa Clara, California, United States, 95051 | |
| Santa Clara, California, United States, 95051 | |
| Kaiser Permanente Medical Center - Santa Rosa | |
| Santa Rosa, California, United States, 95403 | |
| Kaiser Permanente Medical Center - South San Francisco | |
| South San Francisco, California, United States, 94080 | |
| Kaiser Permanente Medical Facility - Stockton | |
| Stockton, California, United States, 95210 | |
| Solano Radiation Oncology Center | |
| Vacaville, California, United States, 95687 | |
| Sutter Solano Medical Center | |
| Vallejo, California, United States, 94589 | |
| Kaiser Permanente Medical Center - Walnut Creek | |
| Walnut Creek, California, United States, 94596 | |
| United States, Connecticut | |
| Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center | |
| Hartford, Connecticut, United States, 06105 | |
| Hospital of Saint Raphael | |
| New Haven, Connecticut, United States, 06511 | |
| United States, Delaware | |
| CCOP - Christiana Care Health Services | |
| Newark, Delaware, United States, 19713 | |
| United States, District of Columbia | |
| Sibley Memorial Hospital | |
| Washington, District of Columbia, United States, 20016 | |
| United States, Florida | |
| Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital | |
| Fort Lauderdale, Florida, United States, 33308 | |
| Ella Milbank Foshay Cancer Center at Jupiter Medical Center | |
| Jupiter, Florida, United States, 33458 | |
| CCOP - Mount Sinai Medical Center | |
| Miami Beach, Florida, United States, 33140 | |
| United States, Georgia | |
| Northeast Georgia Medical Center | |
| Gainesville, Georgia, United States, 30501 | |
| United States, Idaho | |
| Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center | |
| Boise, Idaho, United States, 83706 | |
| United States, Illinois | |
| Cancer Institute at St. John's Hospital | |
| Springfield, Illinois, United States, 62702 | |
| Regional Cancer Center at Memorial Medical Center | |
| Springfield, Illinois, United States, 62781-0001 | |
| United States, Kansas | |
| Menorah Medical Center | |
| Overland Park, Kansas, United States, 66209 | |
| CCOP - Kansas City | |
| Prairie Village, Kansas, United States, 66208 | |
| United States, Maryland | |
| Greenebaum Cancer Center at University of Maryland Medical Center | |
| Baltimore, Maryland, United States, 21201 | |
| St. Agnes Hospital Cancer Center | |
| Baltimore, Maryland, United States, 21229 | |
| United States, Massachusetts | |
| Cape Cod Hospital | |
| Hyannis, Massachusetts, United States, 02601 | |
| Shields Radiation Oncology Center - Mansfield | |
| Mansfield, Massachusetts, United States, 02048 | |
| South Suburban Oncology Center | |
| Quincy, Massachusetts, United States, 02169 | |
| Winchester Hospital Radiation Oncology Center | |
| Winchester, Massachusetts, United States, 01890 | |
| United States, Michigan | |
| Hickman Cancer Center at Bixby Medical Center | |
| Adrian, Michigan, United States, 49221 | |
| CCOP - Michigan Cancer Research Consortium | |
| Ann Arbor, Michigan, United States, 48106 | |
| Saint Joseph Mercy Cancer Center | |
| Ann Arbor, Michigan, United States, 48106-0995 | |
| Oakwood Cancer Center at Oakwood Hospital and Medical Center | |
| Dearborn, Michigan, United States, 48123-2500 | |
| Hurley Medical Center | |
| Flint, Michigan, United States, 48503 | |
| Genesys Hurley Cancer Institute | |
| Flint, Michigan, United States, 48503 | |
| Van Elslander Cancer Center at St. John Hospital and Medical Center | |
| Grosse Pointe Woods, Michigan, United States, 48236 | |
| Foote Memorial Hospital | |
| Jackson, Michigan, United States, 49201 | |
| Sparrow Regional Cancer Center | |
| Lansing, Michigan, United States, 48912-1811 | |
| St. Mary Mercy Hospital | |
| Livonia, Michigan, United States, 48154 | |
| St. Joseph Mercy Oakland | |
| Pontiac, Michigan, United States, 48341-2985 | |
| Mercy Regional Cancer Center at Mercy Hospital | |
| Port Huron, Michigan, United States, 48060 | |
| Seton Cancer Institute at Saint Mary's - Saginaw | |
| Saginaw, Michigan, United States, 48601 | |
| St. John Macomb Hospital | |
| Warren, Michigan, United States, 48093 | |
| United States, Minnesota | |
| Mayo Clinic Cancer Center | |
| Rochester, Minnesota, United States, 55905 | |
| United States, Missouri | |
| St. Joseph Medical Center | |
| Kansas City, Missouri, United States, 64114 | |
| North Kansas City Hospital | |
| Kansas City, Missouri, United States, 64116 | |
| Saint Luke's Cancer Institute at Saint Luke's Hospital | |
| Kansas City, Missouri, United States, 64111 | |
| Parvin Radiation Oncology | |
| Kansas City, Missouri, United States, 64116 | |
| Research Medical Center | |
| Kansas City, Missouri, United States, 64132 | |
| Liberty Hospital | |
| Liberty, Missouri, United States, 64068 | |
| Heartland Regional Medical Center | |
| Saint Joseph, Missouri, United States, 64506 | |
| Saint Joseph Oncology, Incorporated | |
| Saint Joseph, Missouri, United States, 64507 | |
| Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis | |
| Saint Louis, Missouri, United States, 63110 | |
| Barnes-Jewish West County Hospital | |
| Saint Louis, Missouri, United States, 63141 | |
| Siteman Cancer Center at Barnes-Jewish St. Peters Hospital - St. Peters | |
| Saint Peters, Missouri, United States, 63376 | |
| United States, Nevada | |
| CCOP - Nevada Cancer Research Foundation | |
| Las Vegas, Nevada, United States, 89106 | |
| Nevada Cancer Institute | |
| Las Vegas, Nevada, United States, 89135 | |
| Renown Institute for Cancer at Renown Regional Medical Center | |
| Reno, Nevada, United States, 89502 | |
| United States, New Hampshire | |
| Kingsbury Center for Cancer Care at Cheshire Medical Center | |
| Keene, New Hampshire, United States, 03431 | |
| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | |
| Lebanon, New Hampshire, United States, 03756-0002 | |
| United States, New Jersey | |
| Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton | |
| Marlton, New Jersey, United States, 08053 | |
| Fox Chase Virtua Health Cancer Program at Virtua West Jersey | |
| Voorhees, New Jersey, United States, 08043 | |
| United States, New York | |
| New York Methodist Hospital | |
| Brooklyn, New York, United States, 11215 | |
| Roswell Park Cancer Institute | |
| Buffalo, New York, United States, 14263-0001 | |
| Sands Cancer Center | |
| Canandiaqua, New York, United States, 14424 | |
| Beth Israel Medical Center - Petrie Division | |
| New York, New York, United States, 10003-3803 | |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | |
| Rochester, New York, United States, 14642 | |
| Highland Hospital of Rochester | |
| Rochester, New York, United States, 14620 | |
| University Radiation Oncology at Parkridge Hospital | |
| Rochester, New York, United States, 14626 | |
| United States, North Carolina | |
| Blumenthal Cancer Center at Carolinas Medical Center | |
| Charlotte, North Carolina, United States, 28232-2861 | |
| Coleman Radiation Oncology Center at Carter General Hospital | |
| Morehead City, North Carolina, United States, 28557 | |
| CarolinaEast Cancer Care | |
| New Bern, North Carolina, United States, 28560 | |
| South Atlantic Radiation Oncology, LLC | |
| Supply, North Carolina, United States, 28462 | |
| Coastal Carolina Radiation Oncology Center | |
| Wilmington, North Carolina, United States, 28401 | |
| United States, Ohio | |
| Summa Center for Cancer Care at Akron City Hospital | |
| Akron, Ohio, United States, 44309-2090 | |
| Radiation Oncology Center | |
| Alliance, Ohio, United States, 44601 | |
| Barberton Citizens Hospital | |
| Barberton, Ohio, United States, 44203 | |
| Adena Regional Medical Center | |
| Chillicothe, Ohio, United States, 45601 | |
| Doctors Hospital at Ohio Health | |
| Columbus, Ohio, United States, 43228 | |
| Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center | |
| Columbus, Ohio, United States, 43210-1240 | |
| Mount Carmel Health - West Hospital | |
| Columbus, Ohio, United States, 43222 | |
| Riverside Methodist Hospital Cancer Care | |
| Columbus, Ohio, United States, 43214-3998 | |
| CCOP - Columbus | |
| Columbus, Ohio, United States, 43215 | |
| Grant Medical Center Cancer Care | |
| Columbus, Ohio, United States, 43215 | |
| Grady Memorial Hospital | |
| Delaware, Ohio, United States, 43015 | |
| Community Cancer Center | |
| Elyria, Ohio, United States, 44035 | |
| Hematology Oncology Center | |
| Elyria, Ohio, United States, 44035 | |
| Lima Memorial Hospital | |
| Lima, Ohio, United States, 45804 | |
| Strecker Cancer Center at Marietta Memorial Hospital | |
| Marietta, Ohio, United States, 45750 | |
| Northwest Ohio Oncology Center | |
| Maumee, Ohio, United States, 43537-1839 | |
| Licking Memorial Cancer Care Program at Licking Memorial Hospital | |
| Newark, Ohio, United States, 43055 | |
| St. Charles Mercy Hospital | |
| Oregon, Ohio, United States, 43616 | |
| Cancer Care Center, Incorporated | |
| Salem, Ohio, United States, 44460 | |
| North Coast Cancer Care, Incorporated | |
| Sandusky, Ohio, United States, 44870 | |
| Community Hospital of Springfield and Clark County | |
| Springfield, Ohio, United States, 45505 | |
| Flower Hospital Cancer Center | |
| Sylvania, Ohio, United States, 43560 | |
| Mercy Hospital of Tiffin | |
| Tiffin, Ohio, United States, 44883 | |
| Toledo Hospital | |
| Toledo, Ohio, United States, 43606 | |
| Medical University of Ohio Cancer Center | |
| Toledo, Ohio, United States, 43614 | |
| St. Anne Mercy Hospital | |
| Toledo, Ohio, United States, 43623 | |
| CCOP - Toledo Community Hospital | |
| Toledo, Ohio, United States, 43617 | |
| St. Vincent Mercy Medical Center | |
| Toledo, Ohio, United States, 43608 | |
| Toledo Clinic, Incorporated - Main Clinic | |
| Toledo, Ohio, United States, 43623 | |
| Mount Carmel St. Ann's Cancer Center | |
| Westerville, Ohio, United States, 43081 | |
| Cancer Treatment Center | |
| Wooster, Ohio, United States, 44691 | |
| Genesis - Good Samaritan Hospital | |
| Zanesville, Ohio, United States, 43701 | |
| United States, Pennsylvania | |
| Geisinger Cancer Institute at Geisinger Health | |
| Danville, Pennsylvania, United States, 17822-0001 | |
| Fox Chase Cancer Center - Philadelphia | |
| Philadelphia, Pennsylvania, United States, 19111-2497 | |
| McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center | |
| Reading, Pennsylvania, United States, 19612-6052 | |
| Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center | |
| Wilkes-Barre, Pennsylvania, United States, 18711 | |
| York Cancer Center at Apple Hill Medical Center | |
| York, Pennsylvania, United States, 17405 | |
| United States, Texas | |
| M. D. Anderson Cancer Center at University of Texas | |
| Houston, Texas, United States, 77030-4009 | |
| United States, Utah | |
| Sandra L. Maxwell Cancer Center | |
| Cedar City, Utah, United States, 84720 | |
| Logan Regional Hospital | |
| Logan, Utah, United States, 84321 | |
| Jon and Karen Huntsman Cancer Center at Intermountain Medical Center | |
| Murray, Utah, United States, 84157 | |
| Val and Ann Browning Cancer Center at McKay-Dee Hospital Center | |
| Ogden, Utah, United States, 84403 | |
| Utah Valley Regional Medical Center - Provo | |
| Provo, Utah, United States, 84604 | |
| Dixie Regional Medical Center - East Campus | |
| Saint George, Utah, United States, 84770 | |
| Utah Cancer Specialists at UCS Cancer Center | |
| Salt Lake City, Utah, United States, 84106 | |
| LDS Hospital | |
| Salt Lake City, Utah, United States, 84143 | |
| United States, Vermont | |
| Norris Cotton Cancer Center - North | |
| Saint Johnsbury, Vermont, United States, 05819 | |
| United States, Virginia | |
| Fredericksburg Oncology, Incorporated | |
| Fredericksburg, Virginia, United States, 22401 | |
| Veterans Affairs Medical Center - Richmond | |
| Richmond, Virginia, United States, 23249 | |
| United States, Washington | |
| St. Francis Hospital | |
| Federal Way, Washington, United States, 98003 | |
| Good Samaritan Cancer Center | |
| Puyallup, Washington, United States, 98372 | |
| CCOP - Northwest | |
| Tacoma, Washington, United States, 98405 | |
| Franciscan Cancer Center at St. Joseph Medical Center | |
| Tacoma, Washington, United States, 98405-3004 | |
| MultiCare Regional Cancer Center at Tacoma General Hospital | |
| Tacoma, Washington, United States, 98405 | |
| United States, Wisconsin | |
| Columbia Saint Mary's Hospital - Ozaukee | |
| Mequon, Wisconsin, United States, 53097 | |
| Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center | |
| Milwaukee, Wisconsin, United States, 53215 | |
| Columbia-Saint Mary's Cancer Care Center | |
| Milwaukee, Wisconsin, United States, 53211 | |
| All Saints Cancer Center at Wheaton Franciscan Healthcare | |
| Racine, Wisconsin, United States, 53405 | |
| West Allis Memorial Hospital | |
| West Allis, Wisconsin, United States, 53227 | |
| Canada, Alberta | |
| Cross Cancer Institute at University of Alberta | |
| Edmonton, Alberta, Canada, T6G 1Z2 | |
| Canada, Ontario | |
| Princess Margaret Hospital | |
| Toronto, Ontario, Canada, M5G 2M9 | |
Sponsors and Collaborators
Radiation Therapy Oncology Group
Investigators
| Principal Investigator: | Bradley R. Prestidge, MD | Memorial Hermann Southwest Hospital |
More Information
Additional Information:
No publications provided
| Responsible Party: | Walter John Curran, Jr, Radiation Therapy Oncology Group |
| ClinicalTrials.gov Identifier: | NCT00063882 History of Changes |
| Other Study ID Numbers: | CDR0000288823, RTOG-0232, CTSU |
| Study First Received: | July 8, 2003 |
| Last Updated: | August 3, 2012 |
| Health Authority: | United States: Federal Government |
Keywords provided by National Cancer Institute (NCI):
|
stage IIB prostate cancer stage IIA prostate cancer adenocarcinoma of the prostate |
Additional relevant MeSH terms:
|
Prostatic Neoplasms Genital Neoplasms, Male Urogenital Neoplasms Neoplasms by Site Neoplasms Genital Diseases, Male Prostatic Diseases Iodine |
Anti-Infective Agents, Local Anti-Infective Agents Therapeutic Uses Pharmacologic Actions Trace Elements Micronutrients Growth Substances Physiological Effects of Drugs |
ClinicalTrials.gov processed this record on May 19, 2013