Recruitment Details

Key information relevant to the recruitment process for the overall study, such as dates of the recruitment period and locations
7 medical centers enrolled subjects. A total of 29 subjects were enrolled in the study.

Pre-Assignment Details

Significant events and approaches for the overall study following participant enrollment, but prior to group assignment
No text entered.

Reporting Groups

	Description
Inhaled Nitric Oxide	Inhaled Nitric Oxide administered at 80ppm
Nitrogen Gas	Nitrogen Gas (Placebo) administered at 80ppm

Participant Flow:   Overall Study

	Inhaled Nitric Oxide	Nitrogen Gas
STARTED	13	16
COMPLETED	8	14
NOT COMPLETED	5	2
Inclusion / exclusion criteria	5	1
Adverse Event	0	1

Reporting Groups

	Description
Inhaled Nitric Oxide	Inhaled Nitric Oxide administered at 80ppm
Nitrogen Gas	Nitrogen Gas (Placebo) administered at 80ppm

Baseline Measures

	Inhaled Nitric Oxide	Nitrogen Gas	Total
Number of Participants   [units: participants]	13	16	29
Age   [units: participants]
<=18 years	0	0	0
Between 18 and 65 years	13	16	29
>=65 years	0	0	0
Age   [units: years] Mean ± Standard Deviation	62.3  ± 11.71	63.8  ± 12.41	63.1  ± 11.91
Gender   [units: participants]
Female	5	3	8
Male	8	13	21
Region of Enrollment   [units: participants]
United States	13	16	29

1.  Primary:

Mean Percent of Myocardial Infarction Size to the Fraction of Left Ventricular Size   [ Time Frame: 48-72 hours ]

2.  Secondary:

MI Size at 48-72 Hours   [ Time Frame: 48-72 hours ]

3.  Secondary:

MI Size Normalized to Area at Risk   [ Time Frame: 48-72 hours ]

4.  Secondary:

Myocardial Perfusion at Coronary Angiography   [ Time Frame: at completion of PCI ]

5.  Secondary:

Infarct Transmurality   [ Time Frame: 48-72 hours and 4 months ]

6.  Secondary:

Global & Regional LV Function and LV Mass   [ Time Frame: 48-72 hours and 4 months ]

7.  Secondary:

Change in Global LV Function and Mass   [ Time Frame: between 48-72 hours and 4 months ]

8.  Secondary:

MI Size as a Fraction of LV Size   [ Time Frame: 4 months ]

9.  Secondary:

Resolution of ST Segment Elevation Compared With That Observed at Enrollment   [ Time Frame: 4 hours ]

10.  Secondary:

Troponin T Levels and CPK-MB Area Under the Curve   [ Time Frame: 48 hours ]

11.  Secondary:

Change in Adverse Remodeling Parameters Compared With 48-72 Hrs: Changes in LV End-diastolic Vol, End-systolic Vol, End-diastolic Myocardial Wall Thickness in Infarct, Peri-infarct and Remote Areas, and in Sphericity Index at End-diastole and End-systole   [ Time Frame: 4 months ]