Effects of Eplerenone on Left Ventricular Remodelling Following Heart Attack

This study has been completed.

Study NCT00132093 Information provided by NHS Greater Glasgow and Clyde

First Received: August 18, 2005 Last Updated: April 7, 2006 History of Changes

No Study Results Posted on ClinicalTrials.gov for this Study

About Study Results Reporting on ClinicalTrials.gov

Study Status:	This study has been completed.
Estimated Study Completion Date:	No date given
Estimated Primary Completion Date:	No date given

No publications provided by NHS Greater Glasgow and Clyde

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Weir RA, Tsorlalis IK, Steedman T, Dargie HJ, Fraser R, McMurray JJ, Connell JM. Aldosterone and cortisol predict medium-term left ventricular remodelling following myocardial infarction. Eur J Heart Fail. 2011 Dec;13(12):1305-13. Epub 2011 Sep 22.

Weir RA, Clements S, Steedman T, Dargie HJ, McMurray JJ, Squire IB, Ng LL. Plasma TIMP-4 predicts left ventricular remodeling after acute myocardial infarction. J Card Fail. 2011 Jun;17(6):465-71. Epub 2011 Mar 25.

Weir RA, Murphy CA, Petrie CJ, Martin TN, Balmain S, Clements S, Steedman T, Wagner GS, Dargie HJ, McMurray JJ. Microvascular obstruction remains a portent of adverse remodeling in optimally treated patients with left ventricular systolic dysfunction after acute myocardial infarction. Circ Cardiovasc Imaging. 2010 Jul 1;3(4):360-7. Epub 2010 Mar 26.

Weir RA, Miller AM, Murphy GE, Clements S, Steedman T, Connell JM, McInnes IB, Dargie HJ, McMurray JJ. Serum soluble ST2P: a potential novel mediator in left ventricular and infarct remodeling after acute myocardial infarction. J Am Coll Cardiol. 2010 Jan 19;55(3):243-50.

Weir RA, Martin TN, Murphy CA, Petrie CJ, Clements S, Steedman T, Dargie HJ, Wagner GS. Comparison of serial measurements of infarct size and left ventricular ejection fraction by contrast-enhanced cardiac magnetic resonance imaging and electrocardiographic QRS scoring in reperfused anterior ST-elevation myocardial infarction. J Electrocardiol. 2010 May-Jun;43(3):230-6. Epub 2010 Feb 1.

Weir RA, Mark PB, Petrie CJ, Clements S, Steedman T, Ford I, Ng LL, Squire IB, Wagner GS, McMurray JJ, Dargie HJ. Left ventricular remodeling after acute myocardial infarction: does eplerenone have an effect? Am Heart J. 2009 Jun;157(6):1088-96.

Iraqi W, Rossignol P, Angioi M, Fay R, Nuée J, Ketelslegers JM, Vincent J, Pitt B, Zannad F. Extracellular cardiac matrix biomarkers in patients with acute myocardial infarction complicated by left ventricular dysfunction and heart failure: insights from the Eplerenone Post-Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS) study. Circulation. 2009 May 12;119(18):2471-9. Epub 2009 Apr 27.

Weir RA, Chong KS, Dalzell JR, Petrie CJ, Murphy CA, Steedman T, Mark PB, McDonagh TA, Dargie HJ, McMurray JJ. Plasma apelin concentration is depressed following acute myocardial infarction in man. Eur J Heart Fail. 2009 Jun;11(6):551-8. Epub 2009 Apr 6.

Weir RA, Martin TN, Petrie CJ, Murphy A, Clements S, Steedman T, Wagner GS, McMurray JJ, Dargie HJ. Cardiac and extracardiac abnormalities detected by cardiac magnetic resonance in a post-myocardial infarction cohort. Cardiology. 2009;113(1):1-8. Epub 2008 Oct 10.