The Maternal Lifestyle Study (MLS) - No Study Results Posted - ClinicalTrials.gov

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The Maternal Lifestyle Study (MLS)

This study is ongoing, but not recruiting participants.

Study NCT00059540 Information provided by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

First Received: April 28, 2003 Last Updated: January 9, 2011 History of Changes

No Study Results Posted on ClinicalTrials.gov for this Study

About Study Results Reporting on ClinicalTrials.gov

Study Status:	This study is ongoing, but not recruiting participants.
Estimated Study Completion Date:	March 2011
Primary Completion Date:	March 1995 (Final data collection date for primary outcome measure)

Publications:

Bada HS, Das A, Bauer CR, Shankaran S, Lester B, LaGasse L, Hammond J, Wright LL, Higgins R. Impact of prenatal cocaine exposure on child behavior problems through school age. Pediatrics. 2007 Feb;119(2):e348-59.

Bada HS, Bann CM, Bauer CR, Shankaran S, Lester B, Lagasse L, Hammond J, Whitaker T, Das A, Tan S, Higgins R. Preadolescent behavior problems after prenatal cocaine exposure: Relationship between teacher and caretaker ratings (Maternal Lifestyle Study). Neurotoxicol Teratol. 2010 Jun 30; [Epub ahead of print]

Bada HS, Bauer CR, Shankaran S, Lester B, Wright LL, Verter J, Smeriglio VL, Finnegan LP, Maza PL. Central and autonomic nervous systems' signs associated with in utero exposure to cocaine/opiates. Ann N Y Acad Sci. 1998 Jun 21;846:431-4.

Bada HS, Das A, Bauer CR, Shankaran S, Lester BM, Gard CC, Wright LL, Lagasse L, Higgins R. Low birth weight and preterm births: etiologic fraction attributable to prenatal drug exposure. J Perinatol. 2005 Oct;25(10):631-7.

Bada HS, Langer J, Twomey J, Bursi C, Lagasse L, Bauer CR, Shankaran S, Lester BM, Higgins R, Maza PL. Importance of stability of early living arrangements on behavior outcomes of children with and without prenatal drug exposure. J Dev Behav Pediatr. 2008 Jun;29(3):173-82.

Bagner DM, Sheinkopf SJ, Miller-Loncar C, LaGasse LL, Lester BM, Liu J, Bauer CR, Shankaran S, Bada H, Das A. The effect of parenting stress on child behavior problems in high-risk children with prenatal drug exposure. Child Psychiatry Hum Dev. 2009 Mar;40(1):73-84. Epub 2008 Jul 15.

Bauer CR, Langer JC, Shankaran S, Bada HS, Lester B, Wright LL, Krause-Steinrauf H, Smeriglio VL, Finnegan LP, Maza PL, Verter J. Acute neonatal effects of cocaine exposure during pregnancy. Arch Pediatr Adolesc Med. 2005 Sep;159(9):824-34.

ElSohly MA, Stanford DF, Murphy TP, Lester BM, Wright LL, Smeriglio VL, Verter J, Bauer CR, Shankaran S, Bada HS, Walls HC. Immunoassay and GC-MS procedures for the analysis of drugs of abuse in meconium. J Anal Toxicol. 1999 Oct;23(6):436-45.

Gaskins RB, LaGasse LL, Liu J, Shankaran S, Lester BM, Bada HS, Bauer CR, Das A, Higgins RD, Roberts M. Small for gestational age and higher birth weight predict childhood obesity in preterm infants. Am J Perinatol. 2010 Oct;27(9):721-30. Epub 2010 Apr 20.

Gauthier SM, Bauer CR, Messinger DS, Closius JM. The Bayley Scales of Infant Development. II: Where to start? J Dev Behav Pediatr. 1999 Apr;20(2):75-9. Erratum in: J Dev Behav Pediatr 1999 Jun;20(3):197.

LaGasse LL, Van Vorst RF, Brunner SM, Lester BM. Effects of in utero exposure to cocaine and/or opiates on infants' reaching behavior. Ann N Y Acad Sci. 1998 Jun 21;846:405-7. No abstract available.

Sheinkopf SJ, Lagasse LL, Lester BM, Liu J, Seifer R, Bauer CR, Shankaran S, Bada H, Higgins R, DAS A. Prenatal cocaine exposure: cardiorespiratory function and resilience. Ann N Y Acad Sci. 2006 Dec;1094:354-8.

Lester BM. The Maternal Lifestyles Study. Ann N Y Acad Sci. 1998 Jun 21;846:296-305. No abstract available.

Lester BM, Bagner DM, Liu J, LaGasse LL, Seifer R, Bauer CR, Shankaran S, Bada H, Higgins RD, Das A. Infant neurobehavioral dysregulation: behavior problems in children with prenatal substance exposure. Pediatrics. 2009 Nov;124(5):1355-62. Epub 2009 Oct 12.

Lester BM, Lagasse LL, Shankaran S, Bada HS, Bauer CR, Lin R, Das A, Higgins R. Prenatal cocaine exposure related to cortisol stress reactivity in 11-year-old children. J Pediatr. 2010 Aug;157(2):288-295.e1. Epub 2010 Apr 18.

Levine TP, Liu J, Das A, Lester B, Lagasse L, Shankaran S, Bada HS, Bauer CR, Higgins R. Effects of prenatal cocaine exposure on special education in school-aged children. Pediatrics. 2008 Jul;122(1):e83-91. Epub 2008 Jun 9.

Liu J, Bann C, Lester B, Tronick E, Das A, Lagasse L, Bauer C, Shankaran S, Bada H. Neonatal neurobehavior predicts medical and behavioral outcome. Pediatrics. 2010 Jan;125(1):e90-8. Epub 2009 Dec 7.

Maza PL, Wright LL, Bauer CR, Shankaran S, Bada HS, Lester B, Krause-Steinrauf H, Smeriglio VL, Bowler A, Katsikiotis V. Maternal Lifestyles Study (MLS). Caretaking environment and stability of substance-exposed infants at one month corrected age. Ann N Y Acad Sci. 1998 Jun 21;846:358-61. No abstract available.

Miller-Loncar C, Lester BM, Seifer R, Lagasse LL, Bauer CR, Shankaran S, Bada HS, Wright LL, Smeriglio VL, Bigsby R, Liu J. Predictors of motor development in children prenatally exposed to cocaine. Neurotoxicol Teratol. 2005 Mar-Apr;27(2):213-20. Epub 2004 Nov 25.

Salisbury AL, Lester BM, Seifer R, Lagasse L, Bauer CR, Shankaran S, Bada H, Wright L, Liu J, Poole K. Prenatal cocaine use and maternal depression: effects on infant neurobehavior. Neurotoxicol Teratol. 2007 May-Jun;29(3):331-40. Epub 2006 Dec 14. Erratum in: Neurotoxicol Teratol. 2009 Jan-Feb;31(1):69.

Shankaran S, Das A, Bauer CR, Bada H, Lester B, Wright L, Higgins R, Poole K. Fetal origin of childhood disease: intrauterine growth restriction in term infants and risk for hypertension at 6 years of age. Arch Pediatr Adolesc Med. 2006 Sep;160(9):977-81.

Shankaran S, Lester BM, Das A, Bauer CR, Bada HS, Lagasse L, Higgins R. Impact of maternal substance use during pregnancy on childhood outcome. Semin Fetal Neonatal Med. 2007 Apr;12(2):143-50. Epub 2007 Feb 20. Review.

Sheinkopf SJ, Lagasse LL, Lester BM, Liu J, Seifer R, Bauer CR, Shankaran S, Bada H, Das A. Vagal tone as a resilience factor in children with prenatal cocaine exposure. Dev Psychopathol. 2007 Summer;19(3):649-73.

Sheinkopf SJ, Lester BM, LaGasse LL, Seifer R, Bauer CR, Shankaran S, Bada HS, Poole WK, Wright LL. Interactions between maternal characteristics and neonatal behavior in the prediction of parenting stress and perception of infant temperament. J Pediatr Psychol. 2006 Jan-Feb;31(1):27-40. Epub 2005 Apr 12.

Sheinkopf SJ, Lester BM, Sanes JN, Eliassen JC, Hutchison ER, Seifer R, Lagasse LL, Durston S, Casey BJ. Functional MRI and response inhibition in children exposed to cocaine in utero. Preliminary findings. Dev Neurosci. 2009;31(1-2):159-66. Epub 2009 Apr 17.

Stephens BE, Liu J, Lester B, Lagasse L, Shankaran S, Bada H, Bauer C, Das A, Higgins R. Neurobehavioral assessment predicts motor outcome in preterm infants. J Pediatr. 2010 Mar;156(3):366-71. Epub 2009 Nov 1.

Stone KC, High PC, Miller-Loncar CL, Lagasse LL, Lester BM. Longitudinal study of maternal report of sleep problems in children with prenatal exposure to cocaine and other drugs. Behav Sleep Med. 2009;7(4):196-207.

Stone KC, LaGasse LL, Lester BM, Shankaran S, Bada HS, Bauer CR, Hammond JA. Sleep problems in children with prenatal substance exposure: the Maternal Lifestyle study. Arch Pediatr Adolesc Med. 2010 May;164(5):452-6.

Tronick EZ, Olson K, Rosenberg R, Bohne L, Lu J, Lester BM. Normative neurobehavioral performance of healthy infants on the Neonatal Intensive Care Unit Network Neurobehavioral Scale. Pediatrics. 2004 Mar;113(3 Pt 2):676-8.

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