S0126: Gefitinib in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

This study is ongoing, but not recruiting participants.

Study NCT00029003 Information provided by Southwest Oncology Group

First Received: January 4, 2002 Last Updated: July 18, 2011 History of Changes

No Study Results Posted on ClinicalTrials.gov for this Study

About Study Results Reporting on ClinicalTrials.gov

Study Status:	This study is ongoing, but not recruiting participants.
Estimated Study Completion Date:	No date given
Estimated Primary Completion Date:	No date given

Publications:

West H, Chansky K, Franklin WA, et al.: Long-term survival with gefitinib (ZD 1839) therapy for advanced bronchioloalveolar lung cancer (BAC): Southwest Oncology Group (SWOG) study S0126. [Abstract] J Clin Oncol 26 (Suppl 15): A-8047, 2008.

West HL, Franklin WA, McCoy J, Gumerlock PH, Vance R, Lau DH, Chansky K, Crowley JJ, Gandara DR. Gefitinib therapy in advanced bronchioloalveolar carcinoma: Southwest Oncology Group Study S0126. J Clin Oncol. 2006 Apr 20;24(12):1807-13.

Gumerlock PH, Holland WS, Chen H, et al.: Mutational analysis of K-RAS and EGFR implicates K-RAS as a resistance marker in the Southwest Oncology Group (SWOG) trial S0126 of bronchioalveolar carcinoma (BAC) patients (pts) treated with gefitinib. [Abstract] J Clin Oncol 23 (Suppl 16): A-7008, 623s, 2005.

Hirsch FR, Gandara DR, McCoy J, et al.: Increased EGFR gene copy number detected by FISH is associated with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma (BAC) (S0126). [Abstract] J Clin Oncol 23 (Suppl 16): A-7030, 628s, 2005.

Hirsch FR, Varella-Garcia M, McCoy J, West H, Xavier AC, Gumerlock P, Bunn PA Jr, Franklin WA, Crowley J, Gandara DR; Southwest Oncology Group. Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: a Southwest Oncology Group Study. J Clin Oncol. 2005 Oct 1;23(28):6838-45. Epub 2005 Jul 5.

West H, Franklin WA, Gumerlock PH, et al.: Gefitinib (ZD1839) therapy for advanced bronchioloalveolar lung cancer (BAC): Southwest Oncology Group (SWOG) study S0126. [Abstract] J Clin Oncol 22 (Suppl 14): A-7014, 620s, 2004.

West HL, Franklin WA, Gumerlock P, et al.: ZD1839 (Iressa) in advanced bronchioloalveolar carcinoma (BAC): a preliminary report of SWOG S0126. [Abstract] Lung Cancer 41 (Suppl 2): A-O-187, S56, 2003.