Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia

This study has been completed.

Study NCT00022737 Information provided by National Cancer Institute (NCI)

First Received: August 10, 2001 Last Updated: October 15, 2011 History of Changes

No Study Results Posted on ClinicalTrials.gov for this Study

About Study Results Reporting on ClinicalTrials.gov

Study Status:	This study has been completed.
Estimated Study Completion Date:	No date given
Primary Completion Date:	July 2009 (Final data collection date for primary outcome measure)

Publications:

Carroll AJ, Heerema NA, Devidas M, et al.: Secondary chromosomal abnormalities appear to be less prognostic for children with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL) treated with intensified imatinib and chemotherapy: results of the Children's Oncology Group (COG) study AALL0031. [Abstract] Blood 114 (22): A-2606, 2009.

Chang BH, Willis SG, Stork LC, et al.: Mutational analysis of BCR-Abl from subjects with relapsed Ph+ALL treated on the COG protocol AALL0031: A report from the Children's Oncology Group. [Abstract] Blood 114 (22): A-2634, 2009.

Schultz KR, Bowman WP, Aledo A, Slayton WB, Sather H, Devidas M, Wang C, Davies SM, Gaynon PS, Trigg M, Rutledge R, Burden L, Jorstad D, Carroll A, Heerema NA, Winick N, Borowitz MJ, Hunger SP, Carroll WL, Camitta B. Improved Early Event-Free Survival With Imatinib in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Children's Oncology Group Study. J Clin Oncol. 2009 Oct 5; [Epub ahead of print]

Schultz KR, Bowman WP, Slayton W, et al.: Philadelphia chromosome negative (Ph-) very high risk (VHR) acute lymphoblastic leukemia (ALL) in children and adolescents: the impact of intensified chemotherapy on early event free survival (EFS) in Children's Oncology Group (COG) study AALL0031. [Abstract] Blood 112 (11): A-911, 2008.

Schultz KR, Aledo A, Bowman WP, et al.: Minimal toxicity of imatinib mesylate in combination with intensive chemotherapy for Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL) in children: a report of the Childrens Oncology Group (COG) AALL0031 protocol for very high risk ALL. [Abstract] Blood 108 (11): A-283, 2006.