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Study to Investigate the Safety and Efficacy of Lithium in Volunteers With Amyotrophic Lateral Sclerosis (ALS)
This study has been terminated.
( NINDS DSMB recommended trial be terminated for futility after reviewing an interim analysis of 84 subjects. )
Study NCT00818389 Information provided by Massachusetts General Hospital
First Received on January 6, 2009. Last Updated on March 18, 2011
History of Changes
Related Studies can be found by searching for the Conditions, Interventions, and Sponsors found in this study:
Conditions listed in this trial
Amyotrophic Lateral Sclerosis
Additional conditions recognized in this trial
Motor Neuron Disease
Sclerosis
More general conditions related to this trial
Central Nervous System Diseases
Metabolic Diseases
Nervous System Diseases
Neurodegenerative Diseases
Neuromuscular Diseases
Pathologic Processes
Proteostasis Deficiencies
Spinal Cord Diseases
TDP-43 Proteinopathies
Interventions listed in this trial
Lithium Carbonate
Riluzole
placebo
Additional drug interventions recognized in this trial
Lithium
More general drug interventions related to this trial
Anticonvulsants
Antidepressive Agents
Antimanic Agents
Antipsychotic Agents
Central Nervous System Agents
Central Nervous System Depressants
Enzyme Inhibitors
Excitatory Amino Acid Agents
Excitatory Amino Acid Antagonists
Molecular Mechanisms of Pharmacological Action
Neuroprotective Agents
Neurotransmitter Agents
Pharmacologic Actions
Physiological Effects of Drugs
Protective Agents
Psychotropic Drugs
Therapeutic Uses
Tranquilizing Agents
Sponsors listed in this trial
Massachusetts General Hospital
ALS Association
ALS Society of Canada
National Institute of Neurological Disorders and Stroke (NINDS)
University of Toronto
State University of New York - Upstate Medical University
Columbia University
University of Kentucky
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