Non-invasive Pressure-Volume Analysis (NIPVA): Extending Comprehensive Left Ventricular Pump Function Assessment to More Patients and Settings

This study is currently recruiting participants. (see Contacts and Locations)
Verified September 2013 by Imperial College London
Sponsor:
Information provided by (Responsible Party):
Imperial College London
ClinicalTrials.gov Identifier:
NCT01960894
First received: October 9, 2013
Last updated: October 10, 2013
Last verified: September 2013

October 9, 2013
October 10, 2013
September 2013
September 2014   (final data collection date for primary outcome measure)
Reproducibility between non-invasive pressure-volume analysis and how comparable with invasive pressure-volume analysis. [ Time Frame: Immediate ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01960894 on ClinicalTrials.gov Archive Site
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Non-invasive Pressure-Volume Analysis (NIPVA): Extending Comprehensive Left Ventricular Pump Function Assessment to More Patients and Settings
Non-invasive Pressure-Volume Analysis (NIPVA): Extending Comprehensive Left Ventricular Pump Function Assessment to More Patients and Settings

If the heart fails to pump a sufficient amount of blood, it is crucial to know why in order to provide the best treatment. Pressure-volume analysis is the gold standard for evaluating the heart's pumping function. Unfortunately, current techniques are invasive, so most patients will not get this examination. By combining the strengths of echo-Doppler ultrasound, blood pressure monitoring and biomedical computing, the investigators aim to develop a non-invasive method for pressure-volume analysis, extending its applicability to more patients and settings.

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Observational
Observational Model: Case-Only
Time Perspective: Prospective
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Non-Probability Sample

Patients attending cardiology out-patient clinics

Heart Failure
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
60
September 2014
September 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Individuals, male or female, aged 18-80 years.
  • 30 patients awaiting elective diagnostic coronary angiography will be recruited.
  • 30 patients attending cardiology out-patient clinics will be recruited.

Exclusion Criteria:

  • Patients with atrial fibrillation or other dysrhythmias or those unable to fully comply with the protocol will be excluded
Both
18 Years to 80 Years
Yes
United Kingdom
 
NCT01960894
Protocol_NIPVA Study_v1_050613
No
Imperial College London
Imperial College London
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Imperial College London
September 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP