Role of Stress Cardiac MRI in Predicting Adverse Clinical Events in Patients With Known or Suspected Ischemic Heart Disease

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
Raymond Y. Kwong, MD, Brigham and Women's Hospital
ClinicalTrials.gov Identifier:
NCT01821924
First received: March 27, 2013
Last updated: March 29, 2013
Last verified: March 2013

March 27, 2013
March 29, 2013
January 2012
January 2016   (final data collection date for primary outcome measure)
All-cause mortality, MI, heart failure hospitalization or documentation of an LV ejection fraction < 0.40 after index CMR at a follow-up. [ Time Frame: 5 years ] [ Designated as safety issue: No ]
"Myocardial infarction" will be defined as hospital admission for acute coronary syndrome (defined by positive serum troponin level with documented electrocardiographic changes, clinical syndrome, or need for percutaneous or surgical revascularization). "Heart failure hospitalization" will be defined as any hospitalization for signs and symptoms of volume overload or dyspnea requiring diuretic therapy regardless of LV ejection fraction.
Same as current
Complete list of historical versions of study NCT01821924 on ClinicalTrials.gov Archive Site
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Role of Stress Cardiac MRI in Predicting Adverse Clinical Events in Patients With Known or Suspected Ischemic Heart Disease
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The investigators plan to use retrospective data to assess heart function and structure abnormalities through the use of an approved vasodilating agent for stress cardiac MRI tests. The investigators are interested in how these MRI findings relate to long-term prognosis in people who are at risk for cardiac disease.

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Observational
Observational Model: Cohort
Time Perspective: Retrospective
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Non-Probability Sample

Patients above the age of 21 who are clinically referred for stress cardiac MRI.

Coronary Artery Disease
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Shah R, Heydari B, Coelho-Filho O, Murthy VL, Abbasi S, Feng JH, Pencina M, Neilan TG, Meadows JL, Francis S, Blankstein R, Steigner M, di Carli M, Jerosch-Herold M, Kwong RY. Stress cardiac magnetic resonance imaging provides effective cardiac risk reclassification in patients with known or suspected stable coronary artery disease. Circulation. 2013 Aug 6;128(6):605-14. doi: 10.1161/CIRCULATIONAHA.113.001430. Epub 2013 Jun 26.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
400
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January 2016   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Age >/= 21 years old
  • No contraindications for cardiac MRI (by renal function or metallic hazards)
Both
21 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01821924
2011P000643
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Raymond Y. Kwong, MD, Brigham and Women's Hospital
Brigham and Women's Hospital
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Not Provided
Brigham and Women's Hospital
March 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP