Rapid Versus Slow Ingestion of Mixed Meal: Influence on Islet and Incretin Hormone Secretion in Healthy Volunteers

This study is currently recruiting participants.
Verified December 2013 by Lund University
Sponsor:
Information provided by (Responsible Party):
Bo Ahren, Lund University
ClinicalTrials.gov Identifier:
NCT01779622
First received: January 27, 2013
Last updated: December 19, 2013
Last verified: December 2013

January 27, 2013
December 19, 2013
June 2013
January 2014   (final data collection date for primary outcome measure)
Area under the curve for insulin [ Time Frame: 300 min ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01779622 on ClinicalTrials.gov Archive Site
  • Area under the curve for glucose-dependent insuinotropic polypeptide [ Time Frame: 300 min ] [ Designated as safety issue: No ]
  • Area under the curve for glucagon-like peptide-1 [ Time Frame: 300 min ] [ Designated as safety issue: No ]
Same as current
Area under the curve for glucagon [ Time Frame: 300 min ] [ Designated as safety issue: No ]
Same as current
 
Rapid Versus Slow Ingestion of Mixed Meal: Influence on Islet and Incretin Hormone Secretion in Healthy Volunteers
Rapid Versus Slow Ingestion of Mixed Meal: Influence on Islet and Incretin

To test the influence of rapid versus slow ingestion of a mixed meal on insulin and incretin hormone secretion in healthy volunteers

A mixed meal (524 kcal) is ingested rapidly (within 5 min) or slowly (10-15 min) and changes in insulin, glucagon, GIP and GLP-1 levels are followed for subsequent 300 min

Interventional
Not Provided
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
Healthy Volunteers Recruited From the General Population
Other: Mixed meal
Ingestion of mixed meal
Experimental: 1
Healthy volunteers are ingesting a mixed meal either rapidly or slowly
Intervention: Other: Mixed meal
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
24
June 2014
January 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Healthy subjects

Exclusion Criteria:

  • Diabetes Liver disease Kidney disease Thyroid disease
Both
18 Years to 65 Years
Yes
Not Provided
Sweden
 
NCT01779622
17, 2013-000449-38
Yes
Bo Ahren, Lund University
Lund University
Not Provided
Not Provided
Lund University
December 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP