Ischemic Preconditioning in Endurance Athletes

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Maastricht University Medical Center
ClinicalTrials.gov Identifier:
NCT01774461
First received: July 9, 2012
Last updated: March 18, 2014
Last verified: March 2014

July 9, 2012
March 18, 2014
March 2013
September 2013   (final data collection date for primary outcome measure)
Serum concentrations of cardiac troponins [ Time Frame: 6 hours, 2 hourly time intervals ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01774461 on ClinicalTrials.gov Archive Site
Indices of cardiac function measured by echocardiography [ Time Frame: 2 hours post-exercise ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Ischemic Preconditioning in Endurance Athletes
Influence of Remote Ischemic Preconditioning on Cardiac Function After Endurance Exercise

The aim of this study is to investigate the effect of remote ischemic preconditioning on biochemical and functional indices of cardiac function induced by a 30 km run in healthy trained long distance runners.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Basic Science
Exercise
Other: Remote ischemic preconditioning
Blood pressure cuff placed on upper arm and inflated to 200mmHg for 5 minutes then deflated for 5 minutes - this cycle is repeated a total of 4 times.
  • No Intervention: Sham RIC
    Control treatment (sham RIC) will consist of four 5-minute simulated inflations of a blood pressure cuff placed on the upper arm. The inflations will be separated by 5-minute periods when the blood pressure cuff will be deflated.
  • Active Comparator: Remote ischemic conditioning
    Blood pressure cuff placed on upper arm and inflated to 200mmHg for 5 minutes then deflated for 5 minutes - this cycle is repeated a total of 4 times.
    Intervention: Other: Remote ischemic preconditioning
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
29
September 2013
September 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Informed consent
  • Healthy
  • Age between 18 and 65 years
  • Endurance-trained (two or more training sessions per week)

Exclusion Criteria:

  • Not applicable
Both
18 Years to 65 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Netherlands
 
NCT01774461
METC12-2-038
No
Maastricht University Medical Center
Maastricht University Medical Center
Not Provided
Principal Investigator: Marja van Dieijen-Visser, PhD Department of Clinical Chemistry, MUMC, Maastricht, the Netherlands
Maastricht University Medical Center
March 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP