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Dexamethasone and Block Duration in Upper Extremity

This study is currently recruiting participants. (see Contacts and Locations)
Verified March 2014 by University of Chicago
Sponsor:
Information provided by (Responsible Party):
University of Chicago
ClinicalTrials.gov Identifier:
NCT01756573
First received: December 20, 2012
Last updated: March 27, 2014
Last verified: March 2014

December 20, 2012
March 27, 2014
January 2013
December 2014   (final data collection date for primary outcome measure)
analgesia duration [ Time Frame: 72 hrs ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01756573 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Dexamethasone and Block Duration in Upper Extremity
A Study of the Effect of Dexamethasone on Duration of Upper Extremity Blocks With Bupivacaine

Effect of dexamethasone on prolonging upper extremity block is well known. But it not known if the effect comes from its local effect on the nerves or from its general analgesic effect. In this study we will compare the systemic effect to its local effect to find out if there is a difference or not.

Not Provided
Interventional
Phase 4
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Duration of Pain Relief
  • Drug: Dexamthsone
  • Drug: Bupivacaine
  • Active Comparator: Bupivacaine
    Control
    Intervention: Drug: Bupivacaine
  • Experimental: Bupivacaine with Dexamethasone
    Dexamethasone will be mixed with bupivacaine
    Interventions:
    • Drug: Dexamthsone
    • Drug: Bupivacaine
  • Active Comparator: Intravenous Dexamethasone
    Dexamethasone will be given intravenously
    Interventions:
    • Drug: Dexamthsone
    • Drug: Bupivacaine
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
60
December 2014
December 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • age 18-75, no contraindication to regional anesthesia,

Exclusion Criteria:

  • opioid user, chronic pain conditions, peripheral neuropathy
Both
18 Years to 75 Years
No
Contact: Tariq Malik tmalik@dacc.uchicago.edu
United States
 
NCT01756573
IRB12-2192
No
University of Chicago
University of Chicago
Not Provided
Not Provided
University of Chicago
March 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP