Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease

This study is currently recruiting participants. (see Contacts and Locations)
Verified February 2014 by Region Skane
Sponsor:
Information provided by (Responsible Party):
Region Skane
ClinicalTrials.gov Identifier:
NCT01686984
First received: September 13, 2012
Last updated: March 4, 2014
Last verified: February 2014

September 13, 2012
March 4, 2014
September 2012
September 2014   (final data collection date for primary outcome measure)
Carbon dioxide elimination in a ventilator assisted breath. [ Time Frame: 30 minutes ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01686984 on ClinicalTrials.gov Archive Site
Blood CO2 concentration. [ Time Frame: 30 minutes ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease
Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease

The purpose of this study is to investigate how inspiratory flow pattern influences CO2 elimination in people without primary lung disease.

The hypothesis is that a long mean distribution time, caused by a long postinspiratory pause and high end-inspiratory flow, will promote CO2 exchange in the alveoli.

Not Provided
Interventional
Not Provided
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
  • Pulmonary Gas Exchange
  • Carbon Dioxide
Other: Altered breath
Experimental: Altered breath
The group where the investigators alter the inspiratory and expiratory aspects of a ventilated breath.
Intervention: Other: Altered breath
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
10
December 2014
September 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • No known primary lung disease

Exclusion Criteria:

  • Primary lung disease
Both
18 Years and older
No
Contact: Gunnar Malmkvist, Med.Dr +4646-171035 gunnar.malmkvist@skane.se
Sweden
 
NCT01686984
2012/381
No
Region Skane
Region Skane
Not Provided
Principal Investigator: Mikael Bodelsson, Professor Division of Anesthesia, Skane University Hospital, Lund, Sweden
Region Skane
February 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP