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Embryo Kinetics and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2012 by Instituto Valenciano de Infertilidad, IVI VALENCIA.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
Instituto Valenciano de Infertilidad, IVI VALENCIA
ClinicalTrials.gov Identifier:
NCT01678651
First received: August 31, 2012
Last updated: NA
Last verified: August 2012
History: No changes posted

August 31, 2012
August 31, 2012
August 2012
February 2013   (final data collection date for primary outcome measure)
time of cell cleavage [ Time Frame: February 2012 ] [ Designated as safety issue: No ]
Analysis of cell cleavage
Same as current
No Changes Posted
  • Embryo and oocyte morphology [ Time Frame: February 2012 ] [ Designated as safety issue: No ]
    Analysis of all oocytes
  • Outcome rates (implantation, pregnancy and miscarriage rate) [ Time Frame: February 2012 ] [ Designated as safety issue: No ]
    Time requierd to know all the implantation, pregnancy and miscarriage rate
Same as current
Not Provided
Not Provided
 
Embryo Kinetics and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH
Embryo Kinetcis From Embryos Deriving From Egg Donation Cycle With Different Stimulation Protocol: Recombinant FSH vs Human FSH

Different kinetics markers have been proposed to select embryos with higher implantation rates. The effect of external factors on these markers, such as the stimulation protocol should be analyzed. There are two different types of FSH that are commonly used for in vitro fertilization (IVF) in egg donation cycles, recombinant FSH and human FSH. The effect of each kind of hormone on embryo kinetcis is still unknown. The aim of this study is to observe if there is a difference in embryo kinetics and morphology as well as oocyte morphological parameters between the two types of FSH and therefore to analyze if such markers can be used despite of the stimulation protocols chosen.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Primary Purpose: Treatment
Embryo Kinetics
  • Procedure: Stimulation with human FSH
    Human FSH
  • Procedure: Stimulation with recombinant FSH
    Recombinant FSH
  • Active Comparator: Human FSH
    Human FSH
    Intervention: Procedure: Stimulation with human FSH
  • Active Comparator: Recombinant FSH
    Recombinant FSH
    Intervention: Procedure: Stimulation with recombinant FSH
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
80
Not Provided
February 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

•Egg donation cycles with more than 8MII in oocyte retrieval day

Exclusion Criteria:

  • Male factor
  • Uterine malformations
  • genetic alterations
Both
18 Years to 35 Years
Yes
Spain
 
NCT01678651
MAD-NB-08-2012-01
No
Instituto Valenciano de Infertilidad, IVI VALENCIA
Instituto Valenciano de Infertilidad, IVI VALENCIA
Not Provided
Not Provided
Instituto Valenciano de Infertilidad, IVI VALENCIA
August 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP