Neurofeedback as a Treatment Tool for Depression (NFD)

This study is currently recruiting participants.
Verified February 2012 by Cardiff University
Sponsor:
Collaborators:
Medical Research Council
National Institute for Social Care and Health Research
Information provided by (Responsible Party):
David Linden, Cardiff University
ClinicalTrials.gov Identifier:
NCT01544205
First received: February 23, 2012
Last updated: February 28, 2012
Last verified: February 2012

February 23, 2012
February 28, 2012
January 2012
March 2014   (final data collection date for primary outcome measure)
Change in Hamilton Depression Rating Scale (HDRS) score [ Time Frame: Before start trial, after 4 weeks (i.e. 4 sessions), after 2 months (i.e. 5 sessions) and at 5 months (follow-up) ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01544205 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Neurofeedback as a Treatment Tool for Depression
fMRI Based Neurofeedback as a Treatment Method for Depression

The purpose of the study is to investigate whether neurofeedback delivered via functional magnetic resonance imaging signals can be used to train depressed patients to self-regulate emotion networks and whether this improves clinical symptoms.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Unipolar Depression
Other: fMRI-based neurofeedback
5 sessions lasting one hour each
  • Experimental: Emotion network up-regulation
    Intervention: Other: fMRI-based neurofeedback
  • Active Comparator: Place processing network up-regulation
    Intervention: Other: fMRI-based neurofeedback

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
40
Not Provided
March 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • major depressive disorder (MDD) diagnosis
  • stable Selective Serotonin Reuptake Inhibitors (SSRI) dose medication

Exclusion Criteria:

  • Other physical or psychiatric disorders
  • Current substance abuse
  • Current psychotherapy or other specific intervention
  • Exclusion criteria applicable to MRI
Both
18 Years to 65 Years
No
Contact: Isabelle Habes, MD +442920870345 HabesI@cf.ac.uk
Contact: David Linden, Professor +442920687064 LindenD@cf.ac.uk
United Kingdom
 
NCT01544205
SPON927-11, G 1100629, HS/10/25, 11/WA/0106
Not Provided
David Linden, Cardiff University
Cardiff University
  • Medical Research Council
  • National Institute for Social Care and Health Research
Not Provided
Cardiff University
February 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP